Vitamins
8
Vitamin D3 reduces early reflux inflammation
Elevated Pro-inflammatory Cytokine Levels in Acute Reflux Esophagitis Are Reduced by 1,25 Dihydroxy Vitamin D3.
Most Relevant Research
We investigated how Vitamin D3 affects inflammation caused by reflux esophagitis—a condition where stomach acid irritates the esophagus. In our study, we used 70 male rats, dividing them into groups to examine the impact of Vitamin D3 at different doses on inflammation levels.
Our findings revealed that the levels of pro-inflammatory cytokines like IL-1β, IL-6, and IL-8 were significantly elevated in cases of acute reflux esophagitis. However, when we treated these rats with Vitamin D3, we observed that the inflammation markers decreased notably in the acute cases, while there wasn’t any significant change in the chronic cases.
Despite some improvements in cytokine levels with Vitamin D3, we noted that the overall morphological damage to the esophagus remained unchanged. Interestingly, while Vitamin D3 did raise serum calcium levels, it didn’t seem to help repair esophageal damage in the longer-term chronic setting.
These results suggest that while Vitamin D3 has the potential to mitigate inflammation in early stages of reflux esophagitis, it does not offer a complete solution regarding the physical damage caused by the condition over time.
Our findings revealed that the levels of pro-inflammatory cytokines like IL-1β, IL-6, and IL-8 were significantly elevated in cases of acute reflux esophagitis. However, when we treated these rats with Vitamin D3, we observed that the inflammation markers decreased notably in the acute cases, while there wasn’t any significant change in the chronic cases.
Despite some improvements in cytokine levels with Vitamin D3, we noted that the overall morphological damage to the esophagus remained unchanged. Interestingly, while Vitamin D3 did raise serum calcium levels, it didn’t seem to help repair esophageal damage in the longer-term chronic setting.
These results suggest that while Vitamin D3 has the potential to mitigate inflammation in early stages of reflux esophagitis, it does not offer a complete solution regarding the physical damage caused by the condition over time.
9.5
No reflux observed
Most Useful Review
This is the only DHA I prescribe to my patients. It's clean, regulated, and vital for foetal brain and eye development in the third trimester. If you want a clever baby who meets milestones easily, buy this product. The small capsules are easy to swallow and cause minimal reflux. It's best taken with food for optimal absorption.
9.5
Reflux improvement
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Changed my life. This product has been one of the best I've taken, aiding my digestion and joint issues. I had torn both my shoulder labrums, and this supplement has helped me recover to about 90%. Previously, I struggled with severe acid reflux, but now I can enjoy coffee without any problems. Excellent product!
9.5
Stomach pain relief
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Amazing! My husband has battled gastric problems for four years. Last week, he woke up coughing from acid reflux, which was the last straw. Thankfully, I found this product. After just one day of use, along with Life Flora probiotics, his stomach pain disappeared, and he hasn't had any indigestion since starting this. It’s a fantastic product that truly saved my husband's stomach!
Papain
9.5
Effective reflux remedy
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Superb remedy! I have suffered from superficial gastritis and reflux for a long time. This is one of the few products that helps me feel normal without unpleasant symptoms. Unlike other antacids, it truly alleviates my discomfort in the esophagus. I always keep it on hand and will continue to order it!
9.5
Alternative for reflux
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This is a great alternative for alleviating reflux and dry mouth instead of unhealthy options. It also contains chlorophyll, which acts as an internal cleanser.
Flax Seed Oil
9.5
No reflux issue
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Excellent! This flax oil is the best for Omega 3. It's vegan and easy to swallow, even though the capsule is large. Unlike cod liver oil, which caused me acidity and reflux, this one is gentle and doesn't lead to nausea. I recommend it to anyone advised by a nutrition consultant.
9.5
No reflux benefits
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I love this product! Unlike other flax oils, I don't experience reflux with this one, indicating better absorption. The quality is good, and I will certainly purchase it again.
Probiotics
9
Probiotic supplement alleviates GERD symptoms
Efficacy of a Food Supplement Containing LA14, Peptides, and a Multivitamin Complex in Improving Gastroesophageal Reflux Disease-Related Outcomes and Quality of Life of Subjects Showing Mild-to-Moderate Gastroesophageal Reflux Disease.
Most Relevant Research
We investigated the impact of a dietary supplement containing lactobacillus acidophilus, bioactive peptides, and vitamins on individuals with mild-to-moderate gastroesophageal reflux disease (GERD). Conducted as a randomized, double-blind, placebo-controlled study, we followed fifty-six adults over 28 days.
Participants reported a significant reduction in heartburn frequency and severity with the active supplement compared to the placebo. They also noted a decreased reliance on over-the-counter medications and improved quality of life. Overall, this supplement appears to bring meaningful relief to those struggling with GERD symptoms.
Participants reported a significant reduction in heartburn frequency and severity with the active supplement compared to the placebo. They also noted a decreased reliance on over-the-counter medications and improved quality of life. Overall, this supplement appears to bring meaningful relief to those struggling with GERD symptoms.
8.8
IBS improvement
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I'm surprised! I have tried probiotics before and they did nothing. This product is different; my IBS and reflux have noticeably improved in just four weeks. It's not perfect yet, but I'm hopeful for further improvement.
Docosahexaenoic Acid
9.5
Relief from reflux
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Excellent! This plant-based omega 3 doesn't taste of fish, and I feel better using it as fish omega caused me reflux.
9.5
No reflux issues
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This is the best vegan DHA I've tried. It's carrageenan-free, with no unpleasant aftertaste or reflux. The kids tolerate it well.
Slippery Elm
9.5
Pain relief achieved
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Working preparation; relief for my mother’s reflux came quickly. After trying various medications with limited success, she began taking Elm. Within 3-4 days, the stomach pain subsided, and her mucous membranes started to heal. This product is effective for treating thinned gastric mucosa and may help normalise acidity when paired with enzymes.
8.8
GERD pain reduction
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Slippery elm effectively manages GERD and reflux. My husband switched from PPI medication to taking two slippery elm capsules with meals. Although he still experienced pain occasionally, it has significantly reduced to twice a week. We also make a tea from the powder which alleviates pain immediately.
Apple Cider Vinegar
9.5
Alleviates reflux symptoms
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Great acting nutraceutical! An excellent supplement to enhance protein absorption by improving stomach acidity. It's especially beneficial for those with low stomach acid, common in many. It helps regulate blood glucose, lowers triglycerides and LDL, normalises microflora, and reduces oxidative stress. Also effective against reflux and heartburn.
8
Cost-effective relief
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After struggling with reflux and severe indigestion, I started taking apple cider vinegar after meals. This product is cost-effective, and the added magnesium may help my sleep. It's a pill, not a capsule, and has no strong vinegar smell.
Vitamin B12
9
No worsening reflux
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Nice! It tastes alright and seems strong enough while dissolving well without aggravating my reflux. I took this to help elevate my blood platelets, an issue from chemotherapy. I'm impressed with the quality, especially for the price.
8.8
Improved reflux
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Good value for money! Methylcobalamin is a bioavailable form of B12. I have stomach issues with reflux and low stomach acid, which leads to low B12. For me, a combination with Betaine HCL and Pepsin is essential. Stay healthy!
Proprietary Blendmanna Fraxinus Ornus L)
9.5
Improves reflux symptoms
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An excellent supplement for improving digestion. Bitters speed up bile movement, enhance intestinal motility, and promote regular bowel movements, which reduces my reflux. Following a nutritionist's advice, we are pleased with the results.
8.8
Digestive relief
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Really aids digestion. I have digestive issues, and sometimes food feels stuck. My reflux can be unbearable. Grapefruit helps, but this is perfect when I need more relief. I usually feel better within 5-10 minutes. The taste does not bother me.
Coenzyme Q10
9
CoQ10 may improve heart failure symptoms
Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators.
Most Relevant Research
We investigated the role of coenzyme Q10 (CoQ10) as a supplementary treatment for patients suffering from congestive heart failure, particularly focusing on its impact on reflux symptoms. In this study, we enrolled 2,664 patients across 173 centers in Italy, all of whom were already on standard heart failure treatments. Over three months, participants took daily doses of CoQ10 ranging from 50 to 150 mg, with most having 100 mg.
At the end of the three-month period, we recorded various clinical symptoms. Notably, among patients experiencing reflux, 71.81% reported some level of improvement. This suggests that CoQ10 could offer additional benefits when it comes to managing reflux as a symptom of heart failure.
While we observed favorable trends, we also noted that the improvements could not be solely attributed to CoQ10, given that patients continued their standard treatments. The low rate of side effects, with only 1.5% experiencing adverse reactions, adds to the treatment's appeal. Overall, this study indicates that CoQ10 might enhance quality of life for heart failure patients, including those with reflux symptoms.
At the end of the three-month period, we recorded various clinical symptoms. Notably, among patients experiencing reflux, 71.81% reported some level of improvement. This suggests that CoQ10 could offer additional benefits when it comes to managing reflux as a symptom of heart failure.
While we observed favorable trends, we also noted that the improvements could not be solely attributed to CoQ10, given that patients continued their standard treatments. The low rate of side effects, with only 1.5% experiencing adverse reactions, adds to the treatment's appeal. Overall, this study indicates that CoQ10 might enhance quality of life for heart failure patients, including those with reflux symptoms.
Most Useful Review