Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.2
USERS' SCORE
Good
Based on 8 Reviews
8
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Proprietary Blend Containing 1 billion live cultures† Lactobacillus acidophilus Lactobacillus salivarius Bifidobacterium bifidum Streptococcus thermophilus
175 mg
**
Top Medical Research Studies
9
We investigated the impact of Lactobacillus acidophilus and Bifidobacterium adolescentis on anxiety levels in rats facing acute hypoxia. In our study, 64 male Wistar rats were divided into four groups for comparison. The results showed that rats receiving probiotics exhibited lower oxidative stress and anxiety levels compared to those who did not. Notably, those treated with probiotics went through behavioral tests indicating increased exploratory behavior and decreased anxiety. Overall, our findings suggest that these probiotics offer both antioxidant and anxiety-reducing effects in stressful conditions.
Read More
8
We explored how a novel multi-strain E3 probiotic formula could impact anxiety and other mental health symptoms in a group of 68 individuals with sleep disturbances and mood issues.
Over an 8-week period, participants experienced significant improvements in sleep quality, depressive symptoms, and anxiety levels.
Remarkably, these changes were linked to shifts in their gut microbiome, suggesting that the health of our gut might play a powerful role in our overall mental well-being.
Over an 8-week period, participants experienced significant improvements in sleep quality, depressive symptoms, and anxiety levels.
Remarkably, these changes were linked to shifts in their gut microbiome, suggesting that the health of our gut might play a powerful role in our overall mental well-being.
Read More
7
Probiotics reduced anxiety, depression
This double-blind trial explored how synbiotic and probiotic supplements affect mental health and anemia in hemodialysis patients.
With 75 participants, those receiving synbiotics and probiotics showed a notable decrease in anxiety and depression scores after 12 weeks, compared to a placebo group.
However, there was no meaningful improvement in quality of life reported. Interestingly, the treated group also experienced significant increases in hemoglobin levels, which is beneficial.
With 75 participants, those receiving synbiotics and probiotics showed a notable decrease in anxiety and depression scores after 12 weeks, compared to a placebo group.
However, there was no meaningful improvement in quality of life reported. Interestingly, the treated group also experienced significant increases in hemoglobin levels, which is beneficial.
Read More
Most Useful Reviews
9
Supports anxiety relief
7 people found this helpful
Really amazing! This probiotic product is of high quality with beneficial ingredients. The 150 capsules provide great value. It safeguards the digestive system and supports overall health. It's very effective for constipation and diarrhoea, promotes heart health by lowering blood pressure and harmful cholesterol, and is particularly helpful for stress relief. For those on medication, it can alleviate anxiety and depression. It also benefits skin health and aids in weight loss, best taken first thing in the morning on an empty stomach. Thank you for this excellent product!
Read More
9
Reduces anxiety effectively
Probiotics significantly improve digestion while also lessening depression and anxiety. They aid in balancing female hormones and enhancing fertility, and can improve skin conditions. Furthermore, probiotics help eliminate and prevent urogenital infections.
Read More
9
Direct anxiety addressing
Dude, I’m just taking it for anxiety. Works brilliantly!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.2
- All Researches
9
We investigated the impact of Lactobacillus acidophilus and Bifidobacterium adolescentis on anxiety levels in rats facing acute hypoxia. In our study, 64 male Wistar rats were divided into four groups for comparison. The results showed that rats receiving probiotics exhibited lower oxidative stress and anxiety levels compared to those who did not. Notably, those treated with probiotics went through behavioral tests indicating increased exploratory behavior and decreased anxiety. Overall, our findings suggest that these probiotics offer both antioxidant and anxiety-reducing effects in stressful conditions.
Read More
8
We explored how a novel multi-strain E3 probiotic formula could impact anxiety and other mental health symptoms in a group of 68 individuals with sleep disturbances and mood issues.
Over an 8-week period, participants experienced significant improvements in sleep quality, depressive symptoms, and anxiety levels.
Remarkably, these changes were linked to shifts in their gut microbiome, suggesting that the health of our gut might play a powerful role in our overall mental well-being.
Over an 8-week period, participants experienced significant improvements in sleep quality, depressive symptoms, and anxiety levels.
Remarkably, these changes were linked to shifts in their gut microbiome, suggesting that the health of our gut might play a powerful role in our overall mental well-being.
Read More
7
Probiotics reduced anxiety, depression
This double-blind trial explored how synbiotic and probiotic supplements affect mental health and anemia in hemodialysis patients.
With 75 participants, those receiving synbiotics and probiotics showed a notable decrease in anxiety and depression scores after 12 weeks, compared to a placebo group.
However, there was no meaningful improvement in quality of life reported. Interestingly, the treated group also experienced significant increases in hemoglobin levels, which is beneficial.
With 75 participants, those receiving synbiotics and probiotics showed a notable decrease in anxiety and depression scores after 12 weeks, compared to a placebo group.
However, there was no meaningful improvement in quality of life reported. Interestingly, the treated group also experienced significant increases in hemoglobin levels, which is beneficial.
Read More
7
Probiotics reduced anxiety symptoms
We examined the role of probiotics, particularly lactobacillus acidophilus, in alleviating anxiety symptoms among patients with generalized anxiety disorder (GAD). In a double-blind, randomized controlled trial involving drug-free participants, we found that those taking probiotics along with sertraline experienced a notable decrease in anxiety compared to those on sertraline alone.
However, the probiotics did not show a significant impact on improving overall quality of life. While there were encouraging results on anxiety scores, the limited effect on quality of life suggests more research is needed to clarify these findings.
However, the probiotics did not show a significant impact on improving overall quality of life. While there were encouraging results on anxiety scores, the limited effect on quality of life suggests more research is needed to clarify these findings.
Read More
7
We examined the effects of Lactobacillus acidophilus on anxiety alongside other symptoms in irritable eye syndrome. In a clinical trial with 40 participants experiencing ocular and anxiety issues, we found that those who received a specially formulated probiotic supplement showed notable improvements in their symptoms compared to a control group.
After 8 weeks, levels of certain immune markers and anxiety symptoms decreased significantly in the treated group, suggesting that targeting inflammation and gut health may provide a new way to tackle anxiety and related disorders.
After 8 weeks, levels of certain immune markers and anxiety symptoms decreased significantly in the treated group, suggesting that targeting inflammation and gut health may provide a new way to tackle anxiety and related disorders.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Supports anxiety relief
7 people found this helpful
Really amazing! This probiotic product is of high quality with beneficial ingredients. The 150 capsules provide great value. It safeguards the digestive system and supports overall health. It's very effective for constipation and diarrhoea, promotes heart health by lowering blood pressure and harmful cholesterol, and is particularly helpful for stress relief. For those on medication, it can alleviate anxiety and depression. It also benefits skin health and aids in weight loss, best taken first thing in the morning on an empty stomach. Thank you for this excellent product!
Read More
9
Reduces anxiety effectively
Probiotics significantly improve digestion while also lessening depression and anxiety. They aid in balancing female hormones and enhancing fertility, and can improve skin conditions. Furthermore, probiotics help eliminate and prevent urogenital infections.
Read More
9
Direct anxiety addressing
Dude, I’m just taking it for anxiety. Works brilliantly!
Read More
7.5
Helps combat anxiety
4 people found this helpful
The quality is excellent and guaranteed; it is a superb nutritional supplement with natural ingredients, including milk whey. It is very beneficial for anxiety, depression, and digestive issues, particularly constipation and flatulence. The quantity offered is right for the price. The packaging is securely closed to preserve the product. While tasteless, it helps maintain prebiotic activity in the intestine.
Read More
7.5
Improves mental health
1 people found this helpful
Good for promoting intestinal health: it restores the microbiome, balances bacteria, and improves constipation. It reduces diarrhoea caused by antibiotics and enhances mental health by alleviating anxiety and depression, while assisting with autism and memory. It also supports heart health by breaking down intestinal bile and lowers cholesterol and blood pressure. Additionally, it helps prevent urinary and vaginal infections and boosts immunity by promoting natural antibody production.
Read More
Frequently Asked Questions
9
Direct anxiety addressing
Dude, I’m just taking it for anxiety. Works brilliantly!
9
Reduces anxiety effectively
Probiotics significantly improve digestion while also lessening depression and anxiety. They aid in balancing female hormones and enhancing fertility, and can improve skin conditions. Furthermore, probiotics help eliminate and prevent urogenital infections.
7.5
Helps combat anxiety
4 people found this helpful
The quality is excellent and guaranteed; it is a superb nutritional supplement with natural ingredients, including milk whey. It is very beneficial for anxiety, depression, and digestive issues, particularly constipation and flatulence. The quantity offered is right for the price. The packaging is securely closed to preserve the product. While tasteless, it helps maintain prebiotic activity in the intestine.
9
Supports anxiety relief
7 people found this helpful
Really amazing! This probiotic product is of high quality with beneficial ingredients. The 150 capsules provide great value. It safeguards the digestive system and supports overall health. It's very effective for constipation and diarrhoea, promotes heart health by lowering blood pressure and harmful cholesterol, and is particularly helpful for stress relief. For those on medication, it can alleviate anxiety and depression. It also benefits skin health and aids in weight loss, best taken first thing in the morning on an empty stomach. Thank you for this excellent product!
2
Could worsen anxiety
3 people found this helpful
Probiotics may not be unsuitable for everyone; they caused some anxiety and discomfort in my intestines after taking them.
8
We explored how a novel multi-strain E3 probiotic formula could impact anxiety and other mental health symptoms in a group of 68 individuals with sleep disturbances and mood issues.
Over an 8-week period, participants experienced significant improvements in sleep quality, depressive symptoms, and anxiety levels.
Remarkably, these changes were linked to shifts in their gut microbiome, suggesting that the health of our gut might play a powerful role in our overall mental well-being.
Over an 8-week period, participants experienced significant improvements in sleep quality, depressive symptoms, and anxiety levels.
Remarkably, these changes were linked to shifts in their gut microbiome, suggesting that the health of our gut might play a powerful role in our overall mental well-being.
7
Probiotics reduced anxiety, depression
This double-blind trial explored how synbiotic and probiotic supplements affect mental health and anemia in hemodialysis patients.
With 75 participants, those receiving synbiotics and probiotics showed a notable decrease in anxiety and depression scores after 12 weeks, compared to a placebo group.
However, there was no meaningful improvement in quality of life reported. Interestingly, the treated group also experienced significant increases in hemoglobin levels, which is beneficial.
With 75 participants, those receiving synbiotics and probiotics showed a notable decrease in anxiety and depression scores after 12 weeks, compared to a placebo group.
However, there was no meaningful improvement in quality of life reported. Interestingly, the treated group also experienced significant increases in hemoglobin levels, which is beneficial.
7
Probiotics reduced anxiety symptoms
We examined the role of probiotics, particularly lactobacillus acidophilus, in alleviating anxiety symptoms among patients with generalized anxiety disorder (GAD). In a double-blind, randomized controlled trial involving drug-free participants, we found that those taking probiotics along with sertraline experienced a notable decrease in anxiety compared to those on sertraline alone.
However, the probiotics did not show a significant impact on improving overall quality of life. While there were encouraging results on anxiety scores, the limited effect on quality of life suggests more research is needed to clarify these findings.
However, the probiotics did not show a significant impact on improving overall quality of life. While there were encouraging results on anxiety scores, the limited effect on quality of life suggests more research is needed to clarify these findings.
9
We investigated the impact of Lactobacillus acidophilus and Bifidobacterium adolescentis on anxiety levels in rats facing acute hypoxia. In our study, 64 male Wistar rats were divided into four groups for comparison. The results showed that rats receiving probiotics exhibited lower oxidative stress and anxiety levels compared to those who did not. Notably, those treated with probiotics went through behavioral tests indicating increased exploratory behavior and decreased anxiety. Overall, our findings suggest that these probiotics offer both antioxidant and anxiety-reducing effects in stressful conditions.
5
Probiotics did not significantly affect anxiety
We looked into how combining caloric restriction with probiotics affects anxiety in adult men facing obesity. In a well-structured, double-blind, placebo-controlled study, participants followed a 12-week regimen of caloric restriction while taking a specific blend of probiotics.
While we found that anxiety and depressive symptoms improved within the group taking probiotics, there was no significant difference when compared to those on a placebo. This suggests that further research is necessary to fully understand the relationship between probiotics and anxiety in this context.
While we found that anxiety and depressive symptoms improved within the group taking probiotics, there was no significant difference when compared to those on a placebo. This suggests that further research is necessary to fully understand the relationship between probiotics and anxiety in this context.
References
- Marques CG, Dos Santos Quaresma MVL, França Ferracini CB, Alves Carrilho FB, Nakamoto FP, et al. Effect of caloric restriction with probiotic supplementation on body composition, quality of life, and psychobiological factors of obese men: A randomized, double-blinded placebo-controlled clinical trial. Clin Nutr. 2025;45:234. 10.1016/j.clnu.2024.12.031
- Chan HHY, Siu PLK, Choy CT, Chan UK, Zhou J, et al. Novel Multi-Strain E3 Probiotic Formulation Improved Mental Health Symptoms and Sleep Quality in Hong Kong Chinese. Nutrients. 2023;15. 10.3390/nu15245037
- Haghighat N, Mohammadshahi M, Shayanpour S, Haghighizadeh MH, Rahmdel S, et al. The Effect of Synbiotic and Probiotic Supplementation on Mental Health Parameters in Patients Undergoing Hemodialysis: A Double-blind, Randomized, Placebo-controlled Trial. Indian J Nephrol. 2021;31:149. 10.4103/ijn.IJN_341_19
- Kozin SV, Kravtsov AA, Kravchenko SV, Ivashchenko LI. [Antioxidant and anxiolytic effect of and under conditions of normobaric hypoxia with hypercapnia]. Vopr Pitan. 2021;90:63. 10.33029/0042-8833-2021-90-2-63-72
- Eskandarzadeh S, Effatpanah M, Khosravi-Darani K, Askari R, Hosseini AF, et al. Efficacy of a multispecies probiotic as adjunctive therapy in generalized anxiety disorder: a double blind, randomized, placebo-controlled trial. Nutr Neurosci. 2021;24:102. 10.1080/1028415X.2019.1598669
- Feher J, Pinter E, Kovács I, Helyes Z, Kemény A, et al. Irritable eye syndrome: neuroimmune mechanisms and benefits of selected nutrients. Ocul Surf. 2014;12:134. 10.1016/j.jtos.2013.09.002
