Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.1
USERS' SCORE
Good
Based on 7 Reviews
8.1
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Proprietary Blend Containing 1 billion live cultures† Lactobacillus acidophilus Lactobacillus salivarius Bifidobacterium bifidum Streptococcus thermophilus
175 mg
**
Top Medical Research Studies
9
Probiotics show promise against colorectal cancer
This study focused on how Lactobacillus acidophilus and Saccharomyces cerevisiae might affect colorectal cancer cells. We discovered that these probiotics could effectively reduce the growth of cancer cells in two specific lines, HT29 and SW480.
Notably, the probiotics influenced the expression of key genes related to cell death and cancer growth, showing an upregulation of tumor-suppressing genes and microRNAs, while downregulating oncogenes. This suggests they could play a significant role in fighting colorectal cancer and contributing to prevention.
Notably, the probiotics influenced the expression of key genes related to cell death and cancer growth, showing an upregulation of tumor-suppressing genes and microRNAs, while downregulating oncogenes. This suggests they could play a significant role in fighting colorectal cancer and contributing to prevention.
Read More
9
We investigated whether Lactobacillus acidophilus can help prevent liver cancer associated with non-alcoholic fatty liver disease (NAFLD-HCC).
Our study involved various mouse models treated with a specific diet and liver cancer-inducing compounds.
We found that L. acidophilus significantly reduced the occurrence of NAFLD-HCC and inhibited the growth of cancer cells by producing a key metabolite called valeric acid.
This suggests that L. acidophilus may serve as a protective supplement against this type of cancer, improving liver health and function.
Our study involved various mouse models treated with a specific diet and liver cancer-inducing compounds.
We found that L. acidophilus significantly reduced the occurrence of NAFLD-HCC and inhibited the growth of cancer cells by producing a key metabolite called valeric acid.
This suggests that L. acidophilus may serve as a protective supplement against this type of cancer, improving liver health and function.
Read More
9
Lactobacillus acidophilus shows promise
We explored the effect of Lactobacillus acidophilus on non-metastatic rectal cancer by studying its influence on the CYLD protein and signaling pathways. In a randomized trial involving 110 patients, those consuming L. acidophilus showed a significant increase in tumor-suppressing CYLD protein and related genes, alongside a decrease in inflammation-related factors compared to a placebo. Impressively, the probiotic group had a higher survival rate after five years. These findings suggest that L. acidophilus can positively influence cancer by modulating inflammatory pathways.
Read More
Most Useful Reviews
7.5
Reduced tumor growth
9 people found this helpful
Excellent product. If used correctly, Lactobacillus acidophilus makes a great contribution to the human body, particularly on three fronts: increasing antimicrobial activity, strengthening the intestinal barrier, and stimulating the immune system. The immunological benefits are significant; L. acidophilus can modulate the immune response by enhancing lymphocyte proliferation. This leads to reduced tumour growth, the inhibition of bacterial cancer enzymes, and lower production of the cytokine that shields tumours from immune surveillance.
Read More
7.5
Reduced tumour growth
9 people found this helpful
If used correctly, Lactobacillus acidophilus greatly contributes to the human body, especially in three areas: increasing antimicrobial activity, strengthening the intestinal barrier, and stimulating immune function. Its immunological benefits include modulation of the immune response through increased lymphocyte proliferation, resulting in reduced tumour growth, inhibition of bacterial cancer enzymes, and diminished production of tumour-protecting cytokines.
Read More
9
Comfortable daily routine
1 people found this helpful
Excellent! As I have cancer, I try to avoid constipation. I've been taking this for years, and although it took a while to get used to, it has made my daily routine comfortable. I'm so grateful for this product.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.1
- All Researches
9.5
Lactobacillus acidophilus improves cancer therapy
We explored how lactobacillus acidophilus can enhance chemodynamic therapy for cancer. By coupling the probiotic with specialized nanosheets loaded with calcium oxide nanoparticles, we observed a notable reduction in tumor size.
This innovative approach led to a significant boost in hydroxyl radical production within the tumor microenvironment, resulting in a remarkable tumor inhibition rate of 96.4%.
The findings suggest that probiotics can help target tumors more effectively and improve treatment outcomes.
This innovative approach led to a significant boost in hydroxyl radical production within the tumor microenvironment, resulting in a remarkable tumor inhibition rate of 96.4%.
The findings suggest that probiotics can help target tumors more effectively and improve treatment outcomes.
Read More
9
We explored the effects of combined treatments with Lactobacillus acidophilus, calcium citrate, and Moringa oleifera extract on colon cancer induced in rats. The study involved administering a carcinogen, DMH, while observing the impact of these treatments over a four-week period.
Results showed that the combined therapy significantly reduced markers of tumor initiation and improved liver histology. Importantly, these treatments maintained normal function in liver and kidney markers. This suggests that Lactobacillus acidophilus, along with calcium and Moringa, could play a promising role in cancer prevention.
Results showed that the combined therapy significantly reduced markers of tumor initiation and improved liver histology. Importantly, these treatments maintained normal function in liver and kidney markers. This suggests that Lactobacillus acidophilus, along with calcium and Moringa, could play a promising role in cancer prevention.
Read More
9
Probiotics show promise against colorectal cancer
This study focused on how Lactobacillus acidophilus and Saccharomyces cerevisiae might affect colorectal cancer cells. We discovered that these probiotics could effectively reduce the growth of cancer cells in two specific lines, HT29 and SW480.
Notably, the probiotics influenced the expression of key genes related to cell death and cancer growth, showing an upregulation of tumor-suppressing genes and microRNAs, while downregulating oncogenes. This suggests they could play a significant role in fighting colorectal cancer and contributing to prevention.
Notably, the probiotics influenced the expression of key genes related to cell death and cancer growth, showing an upregulation of tumor-suppressing genes and microRNAs, while downregulating oncogenes. This suggests they could play a significant role in fighting colorectal cancer and contributing to prevention.
Read More
9
We investigated whether Lactobacillus acidophilus can help prevent liver cancer associated with non-alcoholic fatty liver disease (NAFLD-HCC).
Our study involved various mouse models treated with a specific diet and liver cancer-inducing compounds.
We found that L. acidophilus significantly reduced the occurrence of NAFLD-HCC and inhibited the growth of cancer cells by producing a key metabolite called valeric acid.
This suggests that L. acidophilus may serve as a protective supplement against this type of cancer, improving liver health and function.
Our study involved various mouse models treated with a specific diet and liver cancer-inducing compounds.
We found that L. acidophilus significantly reduced the occurrence of NAFLD-HCC and inhibited the growth of cancer cells by producing a key metabolite called valeric acid.
This suggests that L. acidophilus may serve as a protective supplement against this type of cancer, improving liver health and function.
Read More
9
Lactobacillus acidophilus shows promise
We explored the effect of Lactobacillus acidophilus on non-metastatic rectal cancer by studying its influence on the CYLD protein and signaling pathways. In a randomized trial involving 110 patients, those consuming L. acidophilus showed a significant increase in tumor-suppressing CYLD protein and related genes, alongside a decrease in inflammation-related factors compared to a placebo. Impressively, the probiotic group had a higher survival rate after five years. These findings suggest that L. acidophilus can positively influence cancer by modulating inflammatory pathways.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Reduced tumor growth
9 people found this helpful
Excellent product. If used correctly, Lactobacillus acidophilus makes a great contribution to the human body, particularly on three fronts: increasing antimicrobial activity, strengthening the intestinal barrier, and stimulating the immune system. The immunological benefits are significant; L. acidophilus can modulate the immune response by enhancing lymphocyte proliferation. This leads to reduced tumour growth, the inhibition of bacterial cancer enzymes, and lower production of the cytokine that shields tumours from immune surveillance.
Read More
7.5
Reduced tumour growth
9 people found this helpful
If used correctly, Lactobacillus acidophilus greatly contributes to the human body, especially in three areas: increasing antimicrobial activity, strengthening the intestinal barrier, and stimulating immune function. Its immunological benefits include modulation of the immune response through increased lymphocyte proliferation, resulting in reduced tumour growth, inhibition of bacterial cancer enzymes, and diminished production of tumour-protecting cytokines.
Read More
9
Comfortable daily routine
1 people found this helpful
Excellent! As I have cancer, I try to avoid constipation. I've been taking this for years, and although it took a while to get used to, it has made my daily routine comfortable. I'm so grateful for this product.
Read More
7.5
Prevents cancer development
4 people found this helpful
Lactobacillus acidophilus helps maintain healthy intestinal microflora, increasing acidity to prevent putrefactive microbes, aiding digestion, and inhibiting enzymes that promote cancer cell development. A deficiency in these microorganisms can lead to pathogenic processes in the intestines and chronic indigestion. I add it when fermenting homemade yogurt, yielding excellent results.
Read More
7.5
Reduced cancer risk
1 people found this helpful
Acidophilus is a popular probiotic known for aiding those with lactose intolerance and for reducing the risk of rectal cancer. It can be beneficial for conditions such as diarrhoea, dysbacteriosis, inflammatory diseases of intestines, skin, gastrointestinal tract, and respiratory infections. It is essential to take a probiotic twice daily, before or during meals.
Read More
Frequently Asked Questions
9
Comfortable daily routine
1 people found this helpful
Excellent! As I have cancer, I try to avoid constipation. I've been taking this for years, and although it took a while to get used to, it has made my daily routine comfortable. I'm so grateful for this product.
7.5
Reduced tumor growth
9 people found this helpful
Excellent product. If used correctly, Lactobacillus acidophilus makes a great contribution to the human body, particularly on three fronts: increasing antimicrobial activity, strengthening the intestinal barrier, and stimulating the immune system. The immunological benefits are significant; L. acidophilus can modulate the immune response by enhancing lymphocyte proliferation. This leads to reduced tumour growth, the inhibition of bacterial cancer enzymes, and lower production of the cytokine that shields tumours from immune surveillance.
7.5
Prevents cancer development
4 people found this helpful
Lactobacillus acidophilus helps maintain healthy intestinal microflora, increasing acidity to prevent putrefactive microbes, aiding digestion, and inhibiting enzymes that promote cancer cell development. A deficiency in these microorganisms can lead to pathogenic processes in the intestines and chronic indigestion. I add it when fermenting homemade yogurt, yielding excellent results.
7.5
Reduced tumour growth
9 people found this helpful
If used correctly, Lactobacillus acidophilus greatly contributes to the human body, especially in three areas: increasing antimicrobial activity, strengthening the intestinal barrier, and stimulating immune function. Its immunological benefits include modulation of the immune response through increased lymphocyte proliferation, resulting in reduced tumour growth, inhibition of bacterial cancer enzymes, and diminished production of tumour-protecting cytokines.
7.5
Supports immune system
1 people found this helpful
A good probiotic, suitable for long-term daily use, contains a small dosage of bifidobacteria. After taking it, I noticed an improvement in my gastrointestinal and genitourinary systems. I took one capsule at night. Lactobacillus acidophilus promotes digestion, prevents intestinal infections, strengthens the immune system, inhibits certain cancer types, and helps manage cholesterol levels. It's also effective in reducing vaginal yeast and urinary tract infections.
7.5
Reduced cancer risk
1 people found this helpful
Acidophilus is a popular probiotic known for aiding those with lactose intolerance and for reducing the risk of rectal cancer. It can be beneficial for conditions such as diarrhoea, dysbacteriosis, inflammatory diseases of intestines, skin, gastrointestinal tract, and respiratory infections. It is essential to take a probiotic twice daily, before or during meals.
7
Engineered probiotics target tumor metabolism
We explored the potential of engineered Lactobacillus acidophilus (LA) as a new method to manage tumor lactate levels and improve cancer treatment. The study developed a special coating for LA to help it avoid being attacked by the immune system while delivering enzymes that reduce L-lactate in tumors.
By doing so, we observed a reduction in the immunosuppressive environment, which can help boost the effectiveness of cancer therapies. Moreover, this engineered probiotic not only delivers enzymes but also converts certain immune cells to better fight tumors. However, the overall effectiveness of this approach appears to require more research to assess its viability in cancer treatment.
By doing so, we observed a reduction in the immunosuppressive environment, which can help boost the effectiveness of cancer therapies. Moreover, this engineered probiotic not only delivers enzymes but also converts certain immune cells to better fight tumors. However, the overall effectiveness of this approach appears to require more research to assess its viability in cancer treatment.
9
We explored the effects of combined treatments with Lactobacillus acidophilus, calcium citrate, and Moringa oleifera extract on colon cancer induced in rats. The study involved administering a carcinogen, DMH, while observing the impact of these treatments over a four-week period.
Results showed that the combined therapy significantly reduced markers of tumor initiation and improved liver histology. Importantly, these treatments maintained normal function in liver and kidney markers. This suggests that Lactobacillus acidophilus, along with calcium and Moringa, could play a promising role in cancer prevention.
Results showed that the combined therapy significantly reduced markers of tumor initiation and improved liver histology. Importantly, these treatments maintained normal function in liver and kidney markers. This suggests that Lactobacillus acidophilus, along with calcium and Moringa, could play a promising role in cancer prevention.
8
We explored how probiotics, including Lactobacillus acidophilus, could improve recovery after surgery for distal gastric cancer. In a well-structured study, patients were divided into groups receiving either probiotics or a placebo.
Our findings showed that those taking probiotics had less inflammation and recovered quicker. They also had better nutritional markers and overall health post-surgery. This points to the possibility that probiotics like Lactobacillus acidophilus can play a helpful role in enhancing recovery times for cancer surgery patients.
Our findings showed that those taking probiotics had less inflammation and recovered quicker. They also had better nutritional markers and overall health post-surgery. This points to the possibility that probiotics like Lactobacillus acidophilus can play a helpful role in enhancing recovery times for cancer surgery patients.
7
Probiotics show potential anticancer effects
We explored how fermentation with probiotics like Lactobacillus acidophilus in soymilk might influence cancer activity.
While various probiotic strains were tested, it was Lacticaseibacillus rhamnosus that stood out, showing impressive growth and acidity levels during fermentation.
Both the probiotics and their combinations demonstrated cytotoxic effects against colon and liver cancer cells. However, overall findings don't indicate a significant advantage of Lactobacillus acidophilus specifically in combating cancer compared to other strains.
While various probiotic strains were tested, it was Lacticaseibacillus rhamnosus that stood out, showing impressive growth and acidity levels during fermentation.
Both the probiotics and their combinations demonstrated cytotoxic effects against colon and liver cancer cells. However, overall findings don't indicate a significant advantage of Lactobacillus acidophilus specifically in combating cancer compared to other strains.
References
- Mao L, Xarpidin B, Shi R, Lin Y, Hu H, et al. Natural Enzyme-Loaded Polymeric Stealth Coating-Armed Engineered Probiotics by Disrupting Tumor Lactate Homeostasis to Synergistic Metabolism-Immuno-Enzyme Dynamic Therapy. Adv Sci (Weinh). 2025. 10.1002/advs.202417172
- Nasri F, Alizadeh A, İncili GK, Hayaloğlu AA, Moradi M. Investigating Chemical Composition and Functionality of Lactobacillus acidophilus LA-5 Postbiotics Prepared in Classic and Cheese Whey Media. Probiotics Antimicrob Proteins. 2024. 10.1007/s12602-024-10435-9
- Si R, Hu T, Williams GR, Yang Y, Yang S, et al. Coupling Probiotics with CaO Nanoparticle-Loaded CoFeCe-LDH Nanosheets to Remodel the Tumor Microenvironment for Precise Chemodynamic Therapy. Adv Healthc Mater. 2025;14:e2403373. 10.1002/adhm.202403373
- Kumawat M, Une H. Effect of Lactobacillus acidophilus, Calcium, and Moringa oleifera leaves extract co-administration can prevent chemical-induced carcinogenesis. Arab J Gastroenterol. 2024;25:421. 10.1016/j.ajg.2024.07.015
- Karim MR, Iqbal S, Mohammad S, Kim JH, Ling L, et al. Upgrading Isoquercitrin Concentration via Submerge Fermentation of Mulberry Fruit Extract with Edible Probiotics to Suppress Gene Targets for Controlling Kidney Cancer and Inflammation. J Microbiol. 2024;62:919. 10.1007/s12275-024-00163-8
- Gad AI, Orabi MM, Abou-Taleb KA, Abdelghani DY, Amin SA. In vitro digestive system simulation and anticancer activity of soymilk fermented by probiotics and synbiotics immobilised on agro-industrial residues. Sci Rep. 2024;14:18518. 10.1038/s41598-024-68086-3
- Xiong H, He Z, Wei Y, Li Q, Xiao Q, et al. Probiotic Compounds Enhanced Recovery after Surgery for Patients with Distal Gastric Cancer: A Prospective, Controlled Clinical Trial. Ann Surg Oncol. 2024;31:5240. 10.1245/s10434-024-15394-7
- Al-Asfour A, Bhardwaj RG, Karched M. Growth Suppression of Oral Squamous Cell Carcinoma Cells by Lactobacillus Acidophilus. Int Dent J. 2024;74:1151. 10.1016/j.identj.2024.03.017
- Mirzadeh MA, Eslami M, Ghanbari A, Zarbakhsh S, Yosefi S, et al. Coadministration of doxorubicin with vitamin D3, Lactobacillus acidophilus, and Lactobacillus casei in the 4T1 mouse model of breast cancer: anticancer and enteroprotective effects. Med Oncol. 2024;41:111. 10.1007/s12032-024-02346-0
- Reis SK, Socca EAR, de Souza BR, Genaro SC, Durán N, et al. Effects of probiotic supplementation on chronic inflammatory process modulation in colorectal carcinogenesis. Tissue Cell. 2024;87:102293. 10.1016/j.tice.2023.102293
- Saffar KN, Larypoor M, Torbati MB. Analyzing of colorectal cancerrelated genes and microRNAs expression profiles in response to probiotics Lactobacillus acidophilus and Saccharomyces cerevisiae in colon cancer cell lines. Mol Biol Rep. 2024;51:122. 10.1007/s11033-023-09008-w
- Lau HC, Zhang X, Ji F, Lin Y, Liang W, et al. Lactobacillus acidophilus suppresses non-alcoholic fatty liver disease-associated hepatocellular carcinoma through producing valeric acid. EBioMedicine. 2024;100:104952. 10.1016/j.ebiom.2023.104952
- Erfanian N, Nasseri S, Miraki Feriz A, Safarpour H, Namaei MH. Characterization of Wnt signaling pathway under treatment of Lactobacillus acidophilus postbiotic in colorectal cancer using an integrated in silico and in vitro analysis. Sci Rep. 2023;13:22988. 10.1038/s41598-023-50047-x
- Zamani F, Khalighfard S, Kalhori MR, Poorkhani A, Amiriani T, et al. Expanding CYLD protein in NF-κβ/TNF-α signaling pathway in response to Lactobacillus acidophilus in non-metastatic rectal cancer patients. Med Oncol. 2023;40:302. 10.1007/s12032-023-02170-y
- Shen S, Ren F, Qin H, Bukhari I, Yang J, et al. NCFM and Lp-115 inhibit colonization and gastric inflammation in a murine model. Front Cell Infect Microbiol. 2023;13:1196084. 10.3389/fcimb.2023.1196084
- Abo-Zaid GA, Kenawy AM, El-Deeb NM, Al-Madboly LA. Improvement and enhancement of oligosaccharide production from Lactobacillus acidophilus using statistical experimental designs and its inhibitory effect on colon cancer. Microb Cell Fact. 2023;22:148. 10.1186/s12934-023-02153-8
