Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.3
USERS' SCORE
Good
Based on 10 Reviews
8.7
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Thiamin (as Thiamin Mononitrate, Vitamin B-1)
100 mg
8,333%
Riboflavin (Vitamin B-2) 
100 mg
7,692%
Niacin (as Niacinamide)
100 mg
625%
Vitamin B-6 (as Pyridoxine HCl)
100 mg
5,882%
Folate
667 mcg DFE(400 mcg Folic Acid
167%
Vitamin B-12 (as Cyanocobalamin)
100 mcg
4,167%
Biotin
100 mcg
333%
Pantothenic Acid (as d-Calcium Pantothenate)
100 mg
2,000%
Calcium (as Calcium Carbonate & Dicalcium Phosphate)
124 mg
10%

Top Medical Research Studies

8
Niacin helps alleviate anxiety symptoms
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.

Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Read More
We explored how vitamin B could help fight anxiety and depression linked to nicotine withdrawal in young male rats.

The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.

The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
Read More
7
Vitamin B may alleviate anxiety symptoms
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.

The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
Read More

Most Useful Reviews

10
Life-changing peace
25 people found this helpful
This is the BEST HELP for the Neurotic! Super! I had depression and anxiety-depressive disorder, with a sensation of constant alarm for 10 years. However, after taking a pill, I felt peace for the first time in a decade, transforming my life immediately. I shed the fears that had tormented me for years. Although I had relied on tranquilizers for calmness, now, my friends also use this remedy. It's a shame I didn't discover it earlier; this is REAL HELP. I ADVISE EVERYONE!
Read More
9
Family solution
Due to constant anxiety and our population's distress, the doctor recommended a B-complex for my family. I am very satisfied with the quality, as these vitamins effectively address our needs.
Read More
9
Highly recommended
This excellent B complex is highly recommended for its ability to reduce anxiety and boost energy levels. It offers great value for money.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.3
  • All Researches
8
Niacin helps alleviate anxiety symptoms
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.

Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Read More
We explored how vitamin B could help fight anxiety and depression linked to nicotine withdrawal in young male rats.

The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.

The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
Read More
7
Vitamin B may alleviate anxiety symptoms
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.

The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
Read More
7
Vitamin B aids anxiety recovery
We explored the effects of vitamin B supplementation on anxiety and cognitive function in male Swiss albino mice following traumatic brain injury (TBI). Our research found that vitamin B appears to improve neurological impairments, enhance memory, and reduce anxiety-like behaviors.

Additionally, we saw a reduction in oxidative stress markers, indicating better neuronal health. This suggests that vitamin B not only helps with anxiety but also plays a role in recovery from cognitive dysfunctions associated with TBI.
Read More
7
No significant anxiety improvement
We explored the effectiveness of vitamin B complex in treating anxiety among patients with Post-COVID-19 syndrome (PC19S) through the PreVitaCOV trial. This study involved 240 participants who were given either prednisolone, vitamin B1, B6, and B12, a combination of these treatments, or a placebo. While the trial showed high feasibility and safety, it ultimately did not demonstrate significant benefits in symptom change over placebo in anxiety or other evaluated symptoms.
Read More

User Reviews

USERS' SCORE
Good
Based on 10 Reviews
8.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Life-changing peace
25 people found this helpful
This is the BEST HELP for the Neurotic! Super! I had depression and anxiety-depressive disorder, with a sensation of constant alarm for 10 years. However, after taking a pill, I felt peace for the first time in a decade, transforming my life immediately. I shed the fears that had tormented me for years. Although I had relied on tranquilizers for calmness, now, my friends also use this remedy. It's a shame I didn't discover it earlier; this is REAL HELP. I ADVISE EVERYONE!
Read More
9
Family solution
Due to constant anxiety and our population's distress, the doctor recommended a B-complex for my family. I am very satisfied with the quality, as these vitamins effectively address our needs.
Read More
9
Highly recommended
This excellent B complex is highly recommended for its ability to reduce anxiety and boost energy levels. It offers great value for money.
Read More
9
Calm stability
After incorporating vitamin B into my routine, my anxiety and unexplained depression diminished. I feel more stable, calm, and my sleep quality has improved significantly.
Read More
7.5
Energy boost
This brand is excellent, providing energy and easy-to-swallow tablets that also help combat anxiety effectively.
Read More

Frequently Asked Questions

10
Life-changing peace
25 people found this helpful
This is the BEST HELP for the Neurotic! Super! I had depression and anxiety-depressive disorder, with a sensation of constant alarm for 10 years. However, after taking a pill, I felt peace for the first time in a decade, transforming my life immediately. I shed the fears that had tormented me for years. Although I had relied on tranquilizers for calmness, now, my friends also use this remedy. It's a shame I didn't discover it earlier; this is REAL HELP. I ADVISE EVERYONE!
9
Calm stability
After incorporating vitamin B into my routine, my anxiety and unexplained depression diminished. I feel more stable, calm, and my sleep quality has improved significantly.
7.5
Family usage
We take the B-100 complex as a family. The tablets are small, easy to swallow, and composed of high-quality ingredients. While taking this B-complex, I experience improved sleep and mood, and I have more energy, particularly during anxious periods.
7.5
Stronger sleep
A fantastic magnesium complex with vitamin B6. I took it for sleep disorders, nervousness, and anxiety. After just one tablet at night, I experienced noticeably improved sleep. Although the tablets are large, the results are worthwhile.
9
Highly recommended
This excellent B complex is highly recommended for its ability to reduce anxiety and boost energy levels. It offers great value for money.
9
Family solution
Due to constant anxiety and our population's distress, the doctor recommended a B-complex for my family. I am very satisfied with the quality, as these vitamins effectively address our needs.
7
Vitamin B may alleviate anxiety symptoms
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.

The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
8
Niacin helps alleviate anxiety symptoms
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.

Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
7
No significant anxiety improvement
We explored the effectiveness of vitamin B complex in treating anxiety among patients with Post-COVID-19 syndrome (PC19S) through the PreVitaCOV trial. This study involved 240 participants who were given either prednisolone, vitamin B1, B6, and B12, a combination of these treatments, or a placebo. While the trial showed high feasibility and safety, it ultimately did not demonstrate significant benefits in symptom change over placebo in anxiety or other evaluated symptoms.

References

  1. Chen J, Liu J, Zhang P, Zhang S. [Effects of Vitamin B on Behaviors, Brain Monoamine Neurotransmitters, and Brain-Derived Neurotrophic Factor in Depressive Rats]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2025;56:206. doi:10.12182/20250160608
  2. Samad N, Hameed A, Manzoor N, Shoukat S, Irfan A, et al. Antioxidant and neuro-modulatory effects of niacin prevent D-galactose-induced behavioral deficits and memory impairment. Exp Gerontol. 2024;198:112624. doi:10.1016/j.exger.2024.112624
  3. Yadav P, Nasir F, Sivanandam TM. Neuroprotective effect of vitamin B supplementation on cognitive functions and neuronal morphology at different time intervals after traumatic brain injury in male Swiss albino mice. Neurochem Int. 2024;180:105869. doi:10.1016/j.neuint.2024.105869
  4. Tengelmann C, Joos S, Kaußner Y, Malzahn U, Lunden L, et al. Feasibility, safety and effectiveness of prednisolone and vitamin B1, B6, and B12 in patients with post-COVID-19-syndrome (PreVitaCOV) - protocol of a randomised, double-blind, placebo-controlled multicentre trial in primary care (phase IIIb). BMC Infect Dis. 2024;24:56. doi:10.1186/s12879-023-08925-2
  5. Pahlavani H, Masoudi M, Khoshroo N, Kakhki S, Mahdi Rezavanimehr M, et al. Vitamin B reversed anxiety and depression induced by adolescent nicotine withdrawal through alteration the inflammatory, oxidative and serotoninergic profiles in male rats. Biochem Pharmacol. 2023;217:115832. doi:10.1016/j.bcp.2023.115832
  6. Kakhki S, Goodarzi M, Abbaszade-Cheragheali A, Rajabi M, Masoumipour AH, et al. Folic acid supplementation improved cognitive deficits associated with lithium administration during pregnancy in rat offspring. Int J Dev Neurosci. 2023;83:615. doi:10.1002/jdn.10289
  7. Shemirani F, Titcomb TJ, Saxby SM, Eyck PT, Rubenstein LM, et al. Association of serum homocysteine, folate, and vitamin B and mood following the Swank and Wahls elimination dietary interventions in relapsing-remitting multiple sclerosis: Secondary analysis of the WAVES trial. Mult Scler Relat Disord. 2023;75:104743. doi:10.1016/j.msard.2023.104743
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