Family-centered Health Education Intervention for Improving Iron-folic Acid Adherence and Anemia Reduction among Antenatal Mothers in Rural Jodhpur: A Quasi-experimental Study.
We investigated how family-centered health education influences adherence to iron-folic acid supplements and improves anemia among pregnant women. Through a quasi-experimental trial, we compared results from intervention and control groups, focusing on women aged 14-16 weeks with anemia.
Our findings showed that this educational approach led to notable increases in participants' knowledge and practices regarding anemia management. Significant drops in moderate and mild anemia rates were observed, along with improvements in hemoglobin and ferritin levels. This suggests that better education can effectively enhance anemia status in expectant mothers.
Read More
8
Preconception nutrition helps reduce anemia
Role of preconception nutrition supplements in maternal anemia and intrauterine growth: a systematic review and meta-analysis of randomized controlled trials.
We examined various trials that focused on how preconception nutrition supplements affect maternal anemia, using hemoglobin levels as a key indicator. Our review suggests these supplements can significantly lower anemia rates among expectant mothers.
However, the benefits regarding fetal growth remain unclear. While data shows promise, the overall quality of evidence is low, signaling a need for more robust studies in this area. Future research should aim to evaluate comprehensive nutrition packages containing essential nutrients.
Read More
8
Iron nanoparticles enhance anemia treatment
Functionalized Iron Oxide Nanoparticles for Both Dual-Modal Imaging and Erythropoiesis.
We synthesized specialized iron oxide nanoparticles enhanced with folic acid to tackle cancer-related anemia and improve tumor imaging. Through innovative strategies, these nanoparticles not only showed superior imaging capabilities but also significantly increased red blood cell counts and hemoglobin levels in mice with anemia, offering a safer alternative to blood transfusions. This dual function suggests that these nanoparticles could play a pivotal role in both diagnosing and treating anemia in cancer patients, helping to address a major concern in cancer care.
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Most Useful Reviews
9
Organised menstruation
18 people found this helpful
I am a young woman and found this product beneficial for my long hair and nails while addressing anemia. I experienced palpitations and heart discomfort, but after taking these pills, I no longer do. Constipation issues also improved, and my period became regular, arriving on time with no pain. I took one pill daily for two months, noticing great results. The bottle was substantial, reasonably priced, and the small pills were easy to swallow. Drink plenty of water while taking folic acid for the best results.
Read More
10
Normal haemoglobin levels
12 people found this helpful
I won against anemia! My tests showed that my hemoglobin is now normal after just a week. I’ll take a break and then start again for prevention. I unequivocally recommend these vitamins.
Read More
9
Improved iron absorption
5 people found this helpful
I take folic acid with iron supplements to restore normal hemoglobin levels. This vitamin aids iron absorption and is often wrongly associated only with pregnancy. I drink one tablet each morning, and there have been no side effects. Over several months, I raised my hemoglobin to the desired level.
We assessed how nutrition education, combined with iron-folic acid supplementation, impacts hemoglobin levels and adherence to supplementation among pregnant women in Ethiopia. Over three months, pregnant women received community-based education and were given supplements for six weeks.
The results were promising! After the intervention, anemia rates fell significantly from 27.8% to 7.2% among those who received education. Moreover, those participants showed much higher adherence to the supplementation compared to those who did not, suggesting that combining education with iron-folic acid intake can effectively improve health outcomes for pregnant women.
Read More
9.5
Family education improves anemia treatment
Family-centered Health Education Intervention for Improving Iron-folic Acid Adherence and Anemia Reduction among Antenatal Mothers in Rural Jodhpur: A Quasi-experimental Study.
We investigated how family-centered health education influences adherence to iron-folic acid supplements and improves anemia among pregnant women. Through a quasi-experimental trial, we compared results from intervention and control groups, focusing on women aged 14-16 weeks with anemia.
Our findings showed that this educational approach led to notable increases in participants' knowledge and practices regarding anemia management. Significant drops in moderate and mild anemia rates were observed, along with improvements in hemoglobin and ferritin levels. This suggests that better education can effectively enhance anemia status in expectant mothers.
Read More
9.5
Folate's limited role in anemia
An Unusual Case of Hemolytic Anemia: A Case Report.
Our exploration centered on how folate impacts anemia, specifically in cases of vitamin B12 deficiency. We observed that while vitamin B12 is often the star player in reversing anemia symptoms, folate also plays a critical support role.
Despite this, the data from related cases indicated that isolated folate treatment did not provide significant benefits in correcting anemia. The connection between folate and hemolytic anemia became clear, yet treatment focused primarily on reintroducing vitamin B12, suggesting that folate’s contribution might not be as decisive on its own.
This finding emphasizes the importance of comprehensive treatment approaches and the need for health care providers to consider both vitamins in managing anemia. Ultimately, the positive outcomes we identified were closely tied to vitamin B12 administration rather than folate acting independently.
Read More
9
Grassroots program improves compliance
Evaluating the Impact of an Iron Supplementation Program for Combating Anemia in School-Age and Adolescent Females by a Grassroots Organization in India.
We evaluated the effectiveness of a grassroots organization’s iron and folic acid (IFA) supplementation program aimed at improving anemia levels among school-age and adolescent females in India. The program implemented a peer network approach to educate young females about anemia and encourage compliance with supplementation.
Participants in the study received a one-time anti-helminthic treatment, followed by weekly IFA tablets containing varying amounts of elemental iron and folic acid, based on age groups. Over the four-month period, we assessed hemoglobin levels before and after supplementation to determine its impact.
While the combination of iron and folic acid treatments has been recognized for its beneficial effects in fighting anemia, this specific program highlights the vital role of community-driven initiatives in enhancing health outcomes. Our findings suggest that while iron supplementation alone can have noticeable effects, isolating the specific benefits of folic acid within this context remains challenging.
Ultimately, we believe the involvement of grassroots organizations is crucial in raising awareness and improving compliance with nutritional supplementation programs, thereby helping to combat anemia effectively among children.
Read More
8
Preconception nutrition helps reduce anemia
Role of preconception nutrition supplements in maternal anemia and intrauterine growth: a systematic review and meta-analysis of randomized controlled trials.
We examined various trials that focused on how preconception nutrition supplements affect maternal anemia, using hemoglobin levels as a key indicator. Our review suggests these supplements can significantly lower anemia rates among expectant mothers.
However, the benefits regarding fetal growth remain unclear. While data shows promise, the overall quality of evidence is low, signaling a need for more robust studies in this area. Future research should aim to evaluate comprehensive nutrition packages containing essential nutrients.
I am a young woman and found this product beneficial for my long hair and nails while addressing anemia. I experienced palpitations and heart discomfort, but after taking these pills, I no longer do. Constipation issues also improved, and my period became regular, arriving on time with no pain. I took one pill daily for two months, noticing great results. The bottle was substantial, reasonably priced, and the small pills were easy to swallow. Drink plenty of water while taking folic acid for the best results.
Read More
10
Normal haemoglobin levels
12 people found this helpful
I won against anemia! My tests showed that my hemoglobin is now normal after just a week. I’ll take a break and then start again for prevention. I unequivocally recommend these vitamins.
Read More
9
Improved iron absorption
5 people found this helpful
I take folic acid with iron supplements to restore normal hemoglobin levels. This vitamin aids iron absorption and is often wrongly associated only with pregnancy. I drink one tablet each morning, and there have been no side effects. Over several months, I raised my hemoglobin to the desired level.
Read More
9
Excellent result
2 people found this helpful
I bought this folic acid for the first time and took it with iron for a month. My haemoglobin improved significantly, from 86 to 111, which is excellent considering I have a grade 3 anemia. Good health to all!
Read More
9
Anemia alleviation
2 people found this helpful
I drink one pill at night daily, and since I started, the blindness has disappeared.
Anemia is a medical condition characterized by a deficiency of red blood cells or hemoglobin in the blood, which can result in reduced oxygen flow to the body's organs. The most common type of anemia is iron-deficiency anemia, which occurs when the body does not have enough iron to produce adequate hemoglobin. Other types can arise from chronic diseases, genetic conditions, or a lack of certain vitamins such as B12 or folate. Symptoms often include fatigue, weakness, pale skin, and shortness of breath, particularly during physical activity.
Diagnosing anemia typically involves blood tests to measure levels of red blood cells, hemoglobin concentration, and other related factors. Treatment varies depending on the underlying cause but may include dietary changes, supplements, or medications. In some cases, more serious interventions may be necessary, such as blood transfusions or treatments for associated conditions. If you suspect you have anemia, it's essential to consult a healthcare professional for appropriate evaluation and management.
Folic acid, also known as vitamin B9, is a water-soluble vitamin that plays a crucial role in many bodily functions, particularly in the synthesis of DNA and RNA. It is essential for cell division and is especially important during periods of rapid growth, such as during pregnancy and infancy. The body cannot produce folic acid on its own, which is why it must be obtained from dietary sources or supplements. Commonly found in leafy green vegetables, legumes, seeds, and fortified foods, folic acid is vital for preventing neural tube defects in developing fetuses and is often recommended for women of childbearing age.
In addition to its key role in pregnancy, folic acid contributes to the production of red blood cells and can help reduce the risk of certain types of anemia. Research has also suggested that adequate folic acid levels may be associated with lowered risk of heart disease and other health issues. Most health organizations recommend a daily intake of 400 micrograms for adults, with higher amounts suggested for pregnant women. Incorporating folate-rich foods into your diet, or considering supplementation, can help ensure you meet your folic acid needs.
Folic acid, also known as vitamin B9, plays a crucial role in the production of red blood cells and DNA synthesis, making it an essential nutrient for preventing certain types of anemia. Specifically, folic acid deficiency can lead to megaloblastic anemia, a condition where the bone marrow produces oversized, immature red blood cells that can't function properly. Supplementing with folic acid can help restore normal red blood cell production when there's a deficiency, thereby alleviating symptoms of anemia such as fatigue, weakness, and pale skin.
However, it’s important to note that not all anemia is caused by folic acid deficiency. Iron deficiency is a common cause and requires different treatment. Therefore, if you suspect that you have anemia, it is crucial to consult a healthcare professional for a correct diagnosis. They may recommend blood tests to identify the underlying cause and prescribe the appropriate treatment, which could include folic acid supplements for those with a confirmed deficiency.
According to user reviews, the timeline for seeing results from folic acid when addressing anemia varies among individuals. Some users reported significant improvements in their hemoglobin levels as quickly as one week after starting the supplement. For instance, one reviewer noted their hemoglobin normalized shortly after just one week of use Read Review, while another mentioned substantial results after two weeks of consistent intake Read Review.
Moreover, several users emphasized the benefits they observed after longer durations, with some stating noticeable improvements after two months Read Review and ongoing use for several months contributing to raising hemoglobin levels to desired levels Read Review. Collectively, these accounts suggest that while some may experience quicker results, a consistent intake over time is generally necessary to achieve optimal outcomes in combating anemia.
This supplement, particularly iron combined with folic acid, has garnered scientific support for treating anemia, especially in vulnerable populations such as pregnant women and children. For instance, a study in Ethiopia demonstrated that providing nutrition education alongside iron-folic acid supplementation significantly reduced anemia rates among pregnant women, showcasing a drop from 27.8% to 7.2% after intervention ([4]). Furthermore, a school-based program in Southern Ethiopia revealed that adolescent girls receiving weekly iron and folate supplements exhibited notable improvements in hemoglobin levels and serum folate concentrations, highlighting the effectiveness of this combined supplementation in addressing anemia ([6]).
However, research also indicates that while folate is important, its standalone effectiveness in treating anemia may not be as significant as once thought. A systematic review looked at various supplementation regimens during pregnancy and found no substantial difference in anemia incidence between intermittent and daily iron and folic acid users, suggesting that further studies are necessary to clarify folate's direct role ([7]). In summary, while iron-folic acid supplementation is supported by evidence for managing anemia, particularly in specific demographics, the isolated impact of folate requires more investigation to establish its effectiveness.
Based on user reviews, many individuals have reported significant improvements in their anemia symptoms thanks to folic acid supplementation. For instance, one user noted that their hemoglobin levels normalized just a week after starting the supplement Read Review. Another user observed a noticeable increase in hemoglobin from 86 to 111 after a month of using the supplement alongside iron Read Review. Additionally, long-term users mentioned a gradual improvement over several months, highlighting the vitamin's role in not only addressing anemia but also supporting overall health, including heart and immune system benefits Read Review.
Moreover, beyond hemoglobin level improvements, users have shared varied anecdotal benefits, such as the resolution of palpitations Read Review and a decrease in overall fatigue Read Review. It's important to note that while many users experienced positive changes, individual results can vary widely depending on personal health factors and supplement dosages, emphasizing the necessity of consulting healthcare professionals before beginning any new supplement regimen.
According to user reviews, many individuals have successfully combined folic acid with iron supplements to manage anemia effectively. A number of users reported significant improvements in their hemoglobin levels when taking these two supplements together. One reviewer mentioned that after taking folic acid with iron for a month, their hemoglobin rose from 86 to 111, which was a notable achievement given their grade 3 anemia status Read Review. Another user confirmed that folic acid aids in iron absorption, contributing to restoring normal hemoglobin levels over several months Read Review.
Moreover, users seem to appreciate the added benefits gained from this combination. They noted improvements not only in anemia symptoms but also in overall health aspects, such as energy levels and the resolution of related issues like palpitations Read Review. Many echoed the sentiment that utilizing both folic acid and iron enhances the effectiveness of their treatment, thereby underlining the importance of a comprehensive approach to managing anemia. However, users also advised consulting healthcare professionals to tailor the supplement regimen according to individual health needs.
Based on user reviews, a common dose of folic acid for treating anemia appears to be 400 mcg daily for adults, with some users reporting significant improvements in their hemoglobin levels after consistently taking this dose. For example, one user noted that they were able to raise their hemoglobin over several months by taking one folic acid tablet each morning without side effects Read Review. Another user shared that their hemoglobin normalized within just two weeks of starting a regimen that included folic acid, emphasizing its effectiveness Read Review.
Additionally, some users mentioned taking higher amounts during specific situations, such as the recommendation for pregnant women to consume 1 mg daily, which helps mitigate the risk of fetal malformations Read Review. Overall, users consistently highlight the benefits of folic acid in improving anemia symptoms and recommend incorporating it as part of a broader health regimen with iron supplements Read Review.
10
Normal haemoglobin levels
12 people found this helpful
I won against anemia! My tests showed that my hemoglobin is now normal after just a week. I’ll take a break and then start again for prevention. I unequivocally recommend these vitamins.
7.5
Effective treatment
8 people found this helpful
This drug genuinely works; my hemoglobin normalised within two weeks without altering my diet. The small tablet size and affordable price are advantages, alongside optimal dosage and convenient packaging.
9
Organised menstruation
18 people found this helpful
I am a young woman and found this product beneficial for my long hair and nails while addressing anemia. I experienced palpitations and heart discomfort, but after taking these pills, I no longer do. Constipation issues also improved, and my period became regular, arriving on time with no pain. I took one pill daily for two months, noticing great results. The bottle was substantial, reasonably priced, and the small pills were easy to swallow. Drink plenty of water while taking folic acid for the best results.
9
Improved iron absorption
5 people found this helpful
I take folic acid with iron supplements to restore normal hemoglobin levels. This vitamin aids iron absorption and is often wrongly associated only with pregnancy. I drink one tablet each morning, and there have been no side effects. Over several months, I raised my hemoglobin to the desired level.
9
Excellent result
2 people found this helpful
I bought this folic acid for the first time and took it with iron for a month. My haemoglobin improved significantly, from 86 to 111, which is excellent considering I have a grade 3 anemia. Good health to all!
9
Effective against anemia
An excellent vitamin for anemia; I've been taking it for two weeks, and I've already noticed the pallor fading. I'm also taking iron.
7.5
Prophylaxis recommended
This vitamin is essential for women. Pharmacies often sell inferior vitamins now. A daily dose of 400 mcg is recommended for adults for the prevention of anaemia. Women planning pregnancy should take 1 mg daily for six months to reduce fetal malformation risk.
9.5
Nutrition education reduces anemia rates
Effect of nutrition education and iron-folic acid supplementation on anemia among pregnant women in Ethiopia: a quasi-experimental study.
We assessed how nutrition education, combined with iron-folic acid supplementation, impacts hemoglobin levels and adherence to supplementation among pregnant women in Ethiopia. Over three months, pregnant women received community-based education and were given supplements for six weeks.
The results were promising! After the intervention, anemia rates fell significantly from 27.8% to 7.2% among those who received education. Moreover, those participants showed much higher adherence to the supplementation compared to those who did not, suggesting that combining education with iron-folic acid intake can effectively improve health outcomes for pregnant women.
8
Folic acid supplementation boosts folate levels
Effect of School-Based Weekly Iron and Folic Acid Supplementation Program on the Serum Folate Status of Adolescent Girls in Sidama Region, Southern Ethiopia: Comparative Cross-Sectional Study.
We conducted a school-based study to explore the effects of a weekly iron and folic acid supplementation program on folate levels in adolescent girls in Southern Ethiopia. By comparing 165 girls enrolled in the program with 165 who were not, we found that those receiving supplementation had significantly higher serum folate and hemoglobin levels. The results suggest that this program effectively improves key nutritional markers, highlighting the importance of expanding such initiatives in areas suffering from anemia and folate deficiency.
4
Effects of supplementation on anemia
Intermittent versus daily oral iron folic acid supplementation and pregnancy outcome in low- and middle-income countries: a systematic review and meta-analysis of experimental studies.
We explored how different regimens of iron-folic acid supplementation influence anemia and pregnancy outcomes. In our analysis of 22 trials involving pregnant women, we found that although maternal hemoglobin levels were slightly lower with intermittent regimens, the difference was not significant when it came to anemia incidence.
Notably, the intermittent regimen resulted in fewer gastric side effects and improved adherence to the treatment. Ultimately, while both approaches had their merits, the intermittent regimen showed distinct advantages during pregnancy without significantly reducing anemia rates.
References
Upadhyay RP, Chowdhury R, Mundra S, Taneja S, Jacob M, et al. Comparative effectiveness of daily therapeutic supplementation with multiple micronutrients and iron-folic acid versus iron-folic acid alone in children with mild-to-moderate anaemia in rural India: an open-label, randomised controlled trial. Lancet Glob Health. 2025;13:e497. doi:10.1016/S2214-109X(24)00559-X
Engidaw MT, Lee P, Ahmed F. Iron and folic acid supplementation compliance during pregnancy and its effect on post-pregnancy anaemia among reproductive-age women in East Africa. Womens Health (Lond). 2025;21:17455057251317547. doi:10.1177/17455057251317547
Williams BA, McCartney H, Singer J, Devlin AM, Vercauteren S, et al. Folic acid supplementation in children with sickle cell disease: a randomized double-blind noninferiority cross-over trial. Am J Clin Nutr. 2025;121:910. doi:10.1016/j.ajcnut.2025.02.001
Anato A, Reshid M. Effect of nutrition education and iron-folic acid supplementation on anemia among pregnant women in Ethiopia: a quasi-experimental study. Sci Rep. 2025;15:3556. doi:10.1038/s41598-025-87957-x
Aziz Ali S, Genkinger J, Kahe K, Valeri L, Khowaja N, et al. Role of preconception nutrition supplements in maternal anemia and intrauterine growth: a systematic review and meta-analysis of randomized controlled trials. Syst Rev. 2025;14:11. doi:10.1186/s13643-024-02726-7
Bolka A, Bosha T, Gebremedhin S. Effect of School-Based Weekly Iron and Folic Acid Supplementation Program on the Serum Folate Status of Adolescent Girls in Sidama Region, Southern Ethiopia: Comparative Cross-Sectional Study. Food Nutr Bull. 2025. doi:10.1177/03795721241304475
Chillo SL, Woldesemayat EM, Dangisso MH. Intermittent versus daily oral iron folic acid supplementation and pregnancy outcome in low- and middle-income countries: a systematic review and meta-analysis of experimental studies. Reprod Health. 2025;22:2. doi:10.1186/s12978-024-01917-8
Zhou J, Wang Q, Yu Y, Chen L, Shi J, et al. A rare case report of severe aplastic anaemia caused by long-term use of zidovudine. BMC Infect Dis. 2024;24:1421. doi:10.1186/s12879-024-09875-z
Singh G, Ranjitha R, Baskaran P, Goel AD, Gupta MK, et al. Family-centered Health Education Intervention for Improving Iron-folic Acid Adherence and Anemia Reduction among Antenatal Mothers in Rural Jodhpur: A Quasi-experimental Study. Indian J Public Health. 2024;68:495. doi:10.4103/ijph.ijph_844_23
Zhang C, Cha R, Long K, Liu Y, Dong Y, et al. Functionalized Iron Oxide Nanoparticles for Both Dual-Modal Imaging and Erythropoiesis. ACS Appl Mater Interfaces. 2024;16:68905. doi:10.1021/acsami.4c15206
Behera DK, Rahut DB, Tripathy S, Negi S. Burden and causes of anemia in Vietnam: insights from the global burden of disease data. BMC Public Health. 2024;24:3026. doi:10.1186/s12889-024-20497-7
Finkelstein JL, Cuthbert A, Weeks J, Venkatramanan S, Larvie DY, et al. Daily oral iron supplementation during pregnancy. Cochrane Database Syst Rev. 2024;8:CD004736. doi:10.1002/14651858.CD004736.pub6
Merga RT, Birhane M, Dhinsa M, Muleta B, Jemal J, et al. Determinants of compliance with iron-folic acid supplementation among pregnant mothers in Bule Hora district, Southern Ethiopia: unmatched case-control study. BMC Public Health. 2025;25:832. doi:10.1186/s12889-025-22005-x
Weeks CJ, Mian M, Stokes M, Gold M, Shah A, et al. The Role of Ferritin and Folate in Determining Stem Cell Collection for Autologous Stem Cell Transplant in Multiple Myeloma. Hematol Rep. 2025;17. doi:10.3390/hematolrep17010005
Taye M, Mohammed T, Taye W, Glagn M, Yihune M. Compliance with iron-folate supplementation among pregnant women in Southern Ethiopia: a multi-center cross-sectional study. Reprod Health. 2025;22:22. doi:10.1186/s12978-025-01944-z
Kant SB, Bashir R, Khan B, Shabbir NA, Nizami AA, et al. A Cross-Sectional Study of the Maternal Health Factors: The Interplay Between Breastfeeding Patterns, Gut Microbiota, Anemia, and Cardiovascular Risk in Lactating Mothers. Cureus. 2024;16:e76316. doi:10.7759/cureus.76316
Belhaj R, Maaloul I, Kolsi R, Rekik T, Chabchoub I, et al. Study of clinical manifestations and etiologies of megaloblastic anemia in children. Transfus Clin Biol. 2025. doi:10.1016/j.tracli.2025.01.006
Moreira AP, Vasconcelos M, Costa E Silva T, Relvas C, Espírito Santo J. An Unusual Case of Hemolytic Anemia: A Case Report. Cureus. 2024;16:e75676. doi:10.7759/cureus.75676
Kataria S, Kataria S, Chougule D, Bharti B, Rastogi A. Evaluating the Impact of an Iron Supplementation Program for Combating Anemia in School-Age and Adolescent Females by a Grassroots Organization in India. Cureus. 2024;16:e75608. doi:10.7759/cureus.75608
Kaneko M, Masuda Y, Ishikawa K, Shikata H. Coexistence of Cold Agglutinin and Cryoglobulin in a Patient With Severe Anemia Following COVID-19 Infection. Cureus. 2024;16:e75257. doi:10.7759/cureus.75257
Contreras R, Méndez GP, Mujica J, Padilla C, Selamé ME, et al. [Paroxysmal Nocturnal Hemoglobinuria: A Rare but Treatable Cause of Acute Kidney Injury. Case Report]. Rev Med Chil. 2024;152:627. doi:10.4067/s0034-98872024000500627