Overview

SCIENTIFIC SCORE
Questionable
Based on 21 Researches
6.8
USERS' SCORE
Good
Based on 28 Reviews
8.3
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Folate
667 mcg DFE (400 mcg Folic Acid)
167%
Calcium (as Calcium Carbonate)
100 mg
8%

Top Medical Research Studies

9.5
Family education improves anemia treatment
We investigated how family-centered health education influences adherence to iron-folic acid supplements and improves anemia among pregnant women. Through a quasi-experimental trial, we compared results from intervention and control groups, focusing on women aged 14-16 weeks with anemia.

Our findings showed that this educational approach led to notable increases in participants' knowledge and practices regarding anemia management. Significant drops in moderate and mild anemia rates were observed, along with improvements in hemoglobin and ferritin levels. This suggests that better education can effectively enhance anemia status in expectant mothers.
Read More
8
Preconception nutrition helps reduce anemia
We examined various trials that focused on how preconception nutrition supplements affect maternal anemia, using hemoglobin levels as a key indicator. Our review suggests these supplements can significantly lower anemia rates among expectant mothers.

However, the benefits regarding fetal growth remain unclear. While data shows promise, the overall quality of evidence is low, signaling a need for more robust studies in this area. Future research should aim to evaluate comprehensive nutrition packages containing essential nutrients.
Read More
We synthesized specialized iron oxide nanoparticles enhanced with folic acid to tackle cancer-related anemia and improve tumor imaging. Through innovative strategies, these nanoparticles not only showed superior imaging capabilities but also significantly increased red blood cell counts and hemoglobin levels in mice with anemia, offering a safer alternative to blood transfusions. This dual function suggests that these nanoparticles could play a pivotal role in both diagnosing and treating anemia in cancer patients, helping to address a major concern in cancer care.
Read More

Most Useful Reviews

9
Organised menstruation
18 people found this helpful
I am a young woman and found this product beneficial for my long hair and nails while addressing anemia. I experienced palpitations and heart discomfort, but after taking these pills, I no longer do. Constipation issues also improved, and my period became regular, arriving on time with no pain. I took one pill daily for two months, noticing great results. The bottle was substantial, reasonably priced, and the small pills were easy to swallow. Drink plenty of water while taking folic acid for the best results.
Read More
10
Normal haemoglobin levels
12 people found this helpful
I won against anemia! My tests showed that my hemoglobin is now normal after just a week. I’ll take a break and then start again for prevention. I unequivocally recommend these vitamins.
Read More
9
Improved iron absorption
5 people found this helpful
I take folic acid with iron supplements to restore normal hemoglobin levels. This vitamin aids iron absorption and is often wrongly associated only with pregnancy. I drink one tablet each morning, and there have been no side effects. Over several months, I raised my hemoglobin to the desired level.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 21 Researches
6.8
  • All Researches
9.5
Nutrition education reduces anemia rates
We assessed how nutrition education, combined with iron-folic acid supplementation, impacts hemoglobin levels and adherence to supplementation among pregnant women in Ethiopia. Over three months, pregnant women received community-based education and were given supplements for six weeks.

The results were promising! After the intervention, anemia rates fell significantly from 27.8% to 7.2% among those who received education. Moreover, those participants showed much higher adherence to the supplementation compared to those who did not, suggesting that combining education with iron-folic acid intake can effectively improve health outcomes for pregnant women.
Read More
9.5
Family education improves anemia treatment
We investigated how family-centered health education influences adherence to iron-folic acid supplements and improves anemia among pregnant women. Through a quasi-experimental trial, we compared results from intervention and control groups, focusing on women aged 14-16 weeks with anemia.

Our findings showed that this educational approach led to notable increases in participants' knowledge and practices regarding anemia management. Significant drops in moderate and mild anemia rates were observed, along with improvements in hemoglobin and ferritin levels. This suggests that better education can effectively enhance anemia status in expectant mothers.
Read More
Our exploration centered on how folate impacts anemia, specifically in cases of vitamin B12 deficiency. We observed that while vitamin B12 is often the star player in reversing anemia symptoms, folate also plays a critical support role.

Despite this, the data from related cases indicated that isolated folate treatment did not provide significant benefits in correcting anemia. The connection between folate and hemolytic anemia became clear, yet treatment focused primarily on reintroducing vitamin B12, suggesting that folate’s contribution might not be as decisive on its own.

This finding emphasizes the importance of comprehensive treatment approaches and the need for health care providers to consider both vitamins in managing anemia. Ultimately, the positive outcomes we identified were closely tied to vitamin B12 administration rather than folate acting independently.
Read More
9
Grassroots program improves compliance
We evaluated the effectiveness of a grassroots organization’s iron and folic acid (IFA) supplementation program aimed at improving anemia levels among school-age and adolescent females in India. The program implemented a peer network approach to educate young females about anemia and encourage compliance with supplementation.

Participants in the study received a one-time anti-helminthic treatment, followed by weekly IFA tablets containing varying amounts of elemental iron and folic acid, based on age groups. Over the four-month period, we assessed hemoglobin levels before and after supplementation to determine its impact.

While the combination of iron and folic acid treatments has been recognized for its beneficial effects in fighting anemia, this specific program highlights the vital role of community-driven initiatives in enhancing health outcomes. Our findings suggest that while iron supplementation alone can have noticeable effects, isolating the specific benefits of folic acid within this context remains challenging.

Ultimately, we believe the involvement of grassroots organizations is crucial in raising awareness and improving compliance with nutritional supplementation programs, thereby helping to combat anemia effectively among children.
Read More
8
Preconception nutrition helps reduce anemia
We examined various trials that focused on how preconception nutrition supplements affect maternal anemia, using hemoglobin levels as a key indicator. Our review suggests these supplements can significantly lower anemia rates among expectant mothers.

However, the benefits regarding fetal growth remain unclear. While data shows promise, the overall quality of evidence is low, signaling a need for more robust studies in this area. Future research should aim to evaluate comprehensive nutrition packages containing essential nutrients.
Read More

User Reviews

USERS' SCORE
Good
Based on 28 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Organised menstruation
18 people found this helpful
I am a young woman and found this product beneficial for my long hair and nails while addressing anemia. I experienced palpitations and heart discomfort, but after taking these pills, I no longer do. Constipation issues also improved, and my period became regular, arriving on time with no pain. I took one pill daily for two months, noticing great results. The bottle was substantial, reasonably priced, and the small pills were easy to swallow. Drink plenty of water while taking folic acid for the best results.
Read More
10
Normal haemoglobin levels
12 people found this helpful
I won against anemia! My tests showed that my hemoglobin is now normal after just a week. I’ll take a break and then start again for prevention. I unequivocally recommend these vitamins.
Read More
9
Improved iron absorption
5 people found this helpful
I take folic acid with iron supplements to restore normal hemoglobin levels. This vitamin aids iron absorption and is often wrongly associated only with pregnancy. I drink one tablet each morning, and there have been no side effects. Over several months, I raised my hemoglobin to the desired level.
Read More
9
Excellent result
2 people found this helpful
I bought this folic acid for the first time and took it with iron for a month. My haemoglobin improved significantly, from 86 to 111, which is excellent considering I have a grade 3 anemia. Good health to all!
Read More
9
Anemia alleviation
2 people found this helpful
I drink one pill at night daily, and since I started, the blindness has disappeared.
Read More

Frequently Asked Questions

10
Normal haemoglobin levels
12 people found this helpful
I won against anemia! My tests showed that my hemoglobin is now normal after just a week. I’ll take a break and then start again for prevention. I unequivocally recommend these vitamins.
7.5
Effective treatment
8 people found this helpful
This drug genuinely works; my hemoglobin normalised within two weeks without altering my diet. The small tablet size and affordable price are advantages, alongside optimal dosage and convenient packaging.
9
Organised menstruation
18 people found this helpful
I am a young woman and found this product beneficial for my long hair and nails while addressing anemia. I experienced palpitations and heart discomfort, but after taking these pills, I no longer do. Constipation issues also improved, and my period became regular, arriving on time with no pain. I took one pill daily for two months, noticing great results. The bottle was substantial, reasonably priced, and the small pills were easy to swallow. Drink plenty of water while taking folic acid for the best results.
9
Improved iron absorption
5 people found this helpful
I take folic acid with iron supplements to restore normal hemoglobin levels. This vitamin aids iron absorption and is often wrongly associated only with pregnancy. I drink one tablet each morning, and there have been no side effects. Over several months, I raised my hemoglobin to the desired level.
9
Excellent result
2 people found this helpful
I bought this folic acid for the first time and took it with iron for a month. My haemoglobin improved significantly, from 86 to 111, which is excellent considering I have a grade 3 anemia. Good health to all!
9
Effective against anemia
An excellent vitamin for anemia; I've been taking it for two weeks, and I've already noticed the pallor fading. I'm also taking iron.
7.5
Prophylaxis recommended
This vitamin is essential for women. Pharmacies often sell inferior vitamins now. A daily dose of 400 mcg is recommended for adults for the prevention of anaemia. Women planning pregnancy should take 1 mg daily for six months to reduce fetal malformation risk.
9.5
Nutrition education reduces anemia rates
We assessed how nutrition education, combined with iron-folic acid supplementation, impacts hemoglobin levels and adherence to supplementation among pregnant women in Ethiopia. Over three months, pregnant women received community-based education and were given supplements for six weeks.

The results were promising! After the intervention, anemia rates fell significantly from 27.8% to 7.2% among those who received education. Moreover, those participants showed much higher adherence to the supplementation compared to those who did not, suggesting that combining education with iron-folic acid intake can effectively improve health outcomes for pregnant women.
8
Folic acid supplementation boosts folate levels
We conducted a school-based study to explore the effects of a weekly iron and folic acid supplementation program on folate levels in adolescent girls in Southern Ethiopia. By comparing 165 girls enrolled in the program with 165 who were not, we found that those receiving supplementation had significantly higher serum folate and hemoglobin levels. The results suggest that this program effectively improves key nutritional markers, highlighting the importance of expanding such initiatives in areas suffering from anemia and folate deficiency.
4
Effects of supplementation on anemia
We explored how different regimens of iron-folic acid supplementation influence anemia and pregnancy outcomes. In our analysis of 22 trials involving pregnant women, we found that although maternal hemoglobin levels were slightly lower with intermittent regimens, the difference was not significant when it came to anemia incidence.

Notably, the intermittent regimen resulted in fewer gastric side effects and improved adherence to the treatment. Ultimately, while both approaches had their merits, the intermittent regimen showed distinct advantages during pregnancy without significantly reducing anemia rates.

References

  1. Upadhyay RP, Chowdhury R, Mundra S, Taneja S, Jacob M, et al. Comparative effectiveness of daily therapeutic supplementation with multiple micronutrients and iron-folic acid versus iron-folic acid alone in children with mild-to-moderate anaemia in rural India: an open-label, randomised controlled trial. Lancet Glob Health. 2025;13:e497. doi:10.1016/S2214-109X(24)00559-X
  2. Engidaw MT, Lee P, Ahmed F. Iron and folic acid supplementation compliance during pregnancy and its effect on post-pregnancy anaemia among reproductive-age women in East Africa. Womens Health (Lond). 2025;21:17455057251317547. doi:10.1177/17455057251317547
  3. Williams BA, McCartney H, Singer J, Devlin AM, Vercauteren S, et al. Folic acid supplementation in children with sickle cell disease: a randomized double-blind noninferiority cross-over trial. Am J Clin Nutr. 2025;121:910. doi:10.1016/j.ajcnut.2025.02.001
  4. Anato A, Reshid M. Effect of nutrition education and iron-folic acid supplementation on anemia among pregnant women in Ethiopia: a quasi-experimental study. Sci Rep. 2025;15:3556. doi:10.1038/s41598-025-87957-x
  5. Aziz Ali S, Genkinger J, Kahe K, Valeri L, Khowaja N, et al. Role of preconception nutrition supplements in maternal anemia and intrauterine growth: a systematic review and meta-analysis of randomized controlled trials. Syst Rev. 2025;14:11. doi:10.1186/s13643-024-02726-7
  6. Bolka A, Bosha T, Gebremedhin S. Effect of School-Based Weekly Iron and Folic Acid Supplementation Program on the Serum Folate Status of Adolescent Girls in Sidama Region, Southern Ethiopia: Comparative Cross-Sectional Study. Food Nutr Bull. 2025. doi:10.1177/03795721241304475
  7. Chillo SL, Woldesemayat EM, Dangisso MH. Intermittent versus daily oral iron folic acid supplementation and pregnancy outcome in low- and middle-income countries: a systematic review and meta-analysis of experimental studies. Reprod Health. 2025;22:2. doi:10.1186/s12978-024-01917-8
  8. Zhou J, Wang Q, Yu Y, Chen L, Shi J, et al. A rare case report of severe aplastic anaemia caused by long-term use of zidovudine. BMC Infect Dis. 2024;24:1421. doi:10.1186/s12879-024-09875-z
  9. Singh G, Ranjitha R, Baskaran P, Goel AD, Gupta MK, et al. Family-centered Health Education Intervention for Improving Iron-folic Acid Adherence and Anemia Reduction among Antenatal Mothers in Rural Jodhpur: A Quasi-experimental Study. Indian J Public Health. 2024;68:495. doi:10.4103/ijph.ijph_844_23
  10. Zhang C, Cha R, Long K, Liu Y, Dong Y, et al. Functionalized Iron Oxide Nanoparticles for Both Dual-Modal Imaging and Erythropoiesis. ACS Appl Mater Interfaces. 2024;16:68905. doi:10.1021/acsami.4c15206
  11. Behera DK, Rahut DB, Tripathy S, Negi S. Burden and causes of anemia in Vietnam: insights from the global burden of disease data. BMC Public Health. 2024;24:3026. doi:10.1186/s12889-024-20497-7
  12. Finkelstein JL, Cuthbert A, Weeks J, Venkatramanan S, Larvie DY, et al. Daily oral iron supplementation during pregnancy. Cochrane Database Syst Rev. 2024;8:CD004736. doi:10.1002/14651858.CD004736.pub6
  13. Merga RT, Birhane M, Dhinsa M, Muleta B, Jemal J, et al. Determinants of compliance with iron-folic acid supplementation among pregnant mothers in Bule Hora district, Southern Ethiopia: unmatched case-control study. BMC Public Health. 2025;25:832. doi:10.1186/s12889-025-22005-x
  14. Weeks CJ, Mian M, Stokes M, Gold M, Shah A, et al. The Role of Ferritin and Folate in Determining Stem Cell Collection for Autologous Stem Cell Transplant in Multiple Myeloma. Hematol Rep. 2025;17. doi:10.3390/hematolrep17010005
  15. Taye M, Mohammed T, Taye W, Glagn M, Yihune M. Compliance with iron-folate supplementation among pregnant women in Southern Ethiopia: a multi-center cross-sectional study. Reprod Health. 2025;22:22. doi:10.1186/s12978-025-01944-z
  16. Kant SB, Bashir R, Khan B, Shabbir NA, Nizami AA, et al. A Cross-Sectional Study of the Maternal Health Factors: The Interplay Between Breastfeeding Patterns, Gut Microbiota, Anemia, and Cardiovascular Risk in Lactating Mothers. Cureus. 2024;16:e76316. doi:10.7759/cureus.76316
  17. Belhaj R, Maaloul I, Kolsi R, Rekik T, Chabchoub I, et al. Study of clinical manifestations and etiologies of megaloblastic anemia in children. Transfus Clin Biol. 2025. doi:10.1016/j.tracli.2025.01.006
  18. Moreira AP, Vasconcelos M, Costa E Silva T, Relvas C, Espírito Santo J. An Unusual Case of Hemolytic Anemia: A Case Report. Cureus. 2024;16:e75676. doi:10.7759/cureus.75676
  19. Kataria S, Kataria S, Chougule D, Bharti B, Rastogi A. Evaluating the Impact of an Iron Supplementation Program for Combating Anemia in School-Age and Adolescent Females by a Grassroots Organization in India. Cureus. 2024;16:e75608. doi:10.7759/cureus.75608
  20. Kaneko M, Masuda Y, Ishikawa K, Shikata H. Coexistence of Cold Agglutinin and Cryoglobulin in a Patient With Severe Anemia Following COVID-19 Infection. Cureus. 2024;16:e75257. doi:10.7759/cureus.75257
  21. Contreras R, Méndez GP, Mujica J, Padilla C, Selamé ME, et al. [Paroxysmal Nocturnal Hemoglobinuria: A Rare but Treatable Cause of Acute Kidney Injury. Case Report]. Rev Med Chil. 2024;152:627. doi:10.4067/s0034-98872024000500627
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