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After conducting genetic tests, it was discovered that this patient was heterozygous for the C677T variation of the methylenetetrahydrofolate reductase (MTHFR) gene, which can affect how the body processes folate.
Fortunately, after prescribing L-methylfolate (Deplin), the patient's symptoms significantly improved. This reinforces the potential of L-methylfolate to help individuals with certain genetic predispositions, especially when medications interfere with the body's methylation cycle.
Overall, our findings suggest that for some patients, especially those with MTHFR mutations, treating dizziness with folate could be a promising avenue worth exploring further.
After discovering elevated plasma homocysteine levels, we treated him with folic acid. Remarkably, this treatment effectively normalized his homocysteine levels.
Following treatment, the granulation tissue in his temporal bone healed progressively, although cochlear function was not restored. This case highlights the potential link between high homocysteine and new complications in ear health.
After diagnosing her condition, we administered high-dose oral folic acid along with blood transfusions. Remarkably, her haemoglobin significantly improved after three months of treatment, and she returned to her normal activities.
This case highlights that folic acid deficiency can lead to serious anaemia but responds well to treatment.
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After diagnosing her condition, we administered high-dose oral folic acid along with blood transfusions. Remarkably, her haemoglobin significantly improved after three months of treatment, and she returned to her normal activities.
This case highlights that folic acid deficiency can lead to serious anaemia but responds well to treatment.
After discovering elevated plasma homocysteine levels, we treated him with folic acid. Remarkably, this treatment effectively normalized his homocysteine levels.
Following treatment, the granulation tissue in his temporal bone healed progressively, although cochlear function was not restored. This case highlights the potential link between high homocysteine and new complications in ear health.
After conducting genetic tests, it was discovered that this patient was heterozygous for the C677T variation of the methylenetetrahydrofolate reductase (MTHFR) gene, which can affect how the body processes folate.
Fortunately, after prescribing L-methylfolate (Deplin), the patient's symptoms significantly improved. This reinforces the potential of L-methylfolate to help individuals with certain genetic predispositions, especially when medications interfere with the body's methylation cycle.
Overall, our findings suggest that for some patients, especially those with MTHFR mutations, treating dizziness with folate could be a promising avenue worth exploring further.
Our patient’s homocysteine was significantly higher than normal, likely due to a deficiency in vitamin B, which can impact various bodily functions, including those related to dizziness. To treat this issue, we administered folic acid, a B vitamin that effectively lowered the homocysteine levels.
Remarkably, as the folate treatment took effect, the granulation tissue in the temporal bone began to heal over time—though it's important to note that this healing occurred without restoring cochlear function. Our findings suggest that folate treatment may play a crucial role in managing complications related to dizziness arising from specific underlying conditions like elevated homocysteine.
However, the study highlighted that regular availability of these tablets was crucial for sustained use. Despite some positive motivations, environmental challenges still hampered consistent adherence to iron supplementation.
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Frequently Asked Questions
Dizziness is a term that describes a range of sensations, including feelings of lightheadedness, unsteadiness, or a false sense of spinning, often referred to as vertigo. This condition can be caused by various factors, including inner ear problems, dehydration, low blood pressure, or certain medications. While it might feel like a minor annoyance for some, dizziness can be a warning sign of more serious health issues, particularly if it is sudden or accompanied by other symptoms such as headache, vision changes, or difficulty speaking.
For those experiencing occasional dizziness, remedies may include staying hydrated, avoiding sudden movements, and engaging in balance exercises. However, persistent dizziness warrants a consultation with a healthcare provider, as it can signify underlying health concerns like vestibular disorders or neurological conditions. Understanding the root cause of dizziness is crucial for effective management, whether through lifestyle modifications or more involved medical treatments.
Folic acid, also known as vitamin B9, is a water-soluble vitamin that plays a crucial role in many bodily functions, particularly in the synthesis of DNA and RNA. It is essential for cell division and is especially important during periods of rapid growth, such as during pregnancy and infancy. The body cannot produce folic acid on its own, which is why it must be obtained from dietary sources or supplements. Commonly found in leafy green vegetables, legumes, seeds, and fortified foods, folic acid is vital for preventing neural tube defects in developing fetuses and is often recommended for women of childbearing age.
In addition to its key role in pregnancy, folic acid contributes to the production of red blood cells and can help reduce the risk of certain types of anemia. Research has also suggested that adequate folic acid levels may be associated with lowered risk of heart disease and other health issues. Most health organizations recommend a daily intake of 400 micrograms for adults, with higher amounts suggested for pregnant women. Incorporating folate-rich foods into your diet, or considering supplementation, can help ensure you meet your folic acid needs.
Based on user reviews, the timeline for experiencing results from the supplement can vary. Some users reported relief from dizziness quite quickly; for instance, one user noted that their dizziness faded by the end of the second day of taking the supplement (Read Review). Another user mentioned that after two months of use, their dizziness completely vanished (Read Review).
Overall, while results may be immediate for some, such as improvements in symptoms noted within days, others suggest a longer period may be required for optimal results. Users generally agree that incorporating the supplement into a broader health regimen potentially enhances its effectiveness in alleviating dizziness.
Scientific research indicates that folate, particularly in its L-methylfolate form, can play a significant role in alleviating dizziness, especially in individuals with certain genetic predispositions. For example, one study highlighted a patient with prolonged dizziness who improved remarkably after being treated with L-methylfolate following medication interaction that impeded folate metabolism [5]. This suggests that those with genetic variants affecting folate processing may benefit from such treatments when experiencing dizziness related to their condition.
Moreover, other studies have shown that deficiencies in folate and vitamin B12 are associated with dizziness due to their impact on hematologic health and overall metabolic processes [1] [4]. While not every case isolates folate as the sole remedy for dizziness, its role alongside other treatments appears promising. The collective findings underscore the importance of maintaining adequate folate levels for those experiencing dizziness, particularly when nutritional deficiencies might be involved.
Based on user reviews, many individuals have reported notable improvements in symptoms after beginning their supplementation. For instance, one user observed that their dizziness completely vanished after two months of use, attributing this positive change to the high folic acid content of the product (Read Review). Others experienced quicker relief, with one reviewer stating that their dizziness diminished by the end of just two days of taking the supplement (Read Review).
Additional feedback highlights a broader range of benefits, with several users noting significant enhancements in overall health, energy levels, and even reductions in symptoms like shortness of breath (Read Review). It's important to recognize that while many users report positive outcomes, individual results may vary, and combining the supplement with other health practices, such as taking iron, may further amplify its effectiveness (Read Review).
Users have reported varying experiences when combining this supplement with others to address dizziness. A notable trend among reviewers is the positive impact of pairing this supplement with iron. One user mentioned that by combining it with iron, their orthostatic dizziness completely vanished, underscoring the potential benefits of creating a more comprehensive supplementation approach (Read Review). Others have also expressed improvements in dizziness along with overall health enhancements, although specific combinations weren't detailed in those accounts.
Additionally, several users emphasized that alongside the primary supplement, its effects were amplified when included in a broader regimen focusing on overall health. For instance, one reviewer noted significant improvements in strength and a calming effect on their nervous system, which might suggest that complementary supplements could aid in managing dizziness more effectively (Read Review). While individual experiences vary, the takeaway from numerous reviews is that combining supplements can yield better outcomes for managing dizziness.
According to user reviews, the dosage of Folic Acid that appears effective for alleviating dizziness varies, but several users have reported positive results with specific amounts. One reviewer noted that a daily intake of 400 micrograms, as provided in their product, completely eliminated their dizziness after two months ((Read Review)). Another user mentioned taking Folic Acid twice daily and experienced a notable decrease in dizziness within just two days ((Read Review)).
Several other reviewers corroborated the effectiveness of Folic Acid in mitigating dizziness, often combining it with iron for enhanced results ((Read Review)). The varying personal experiences suggest that while a standard dose like 400 micrograms is noted, individual responses can differ, implying that some users may benefit from adjusted doses based on their specific needs and health conditions.
After conducting genetic tests, it was discovered that this patient was heterozygous for the C677T variation of the methylenetetrahydrofolate reductase (MTHFR) gene, which can affect how the body processes folate.
Fortunately, after prescribing L-methylfolate (Deplin), the patient's symptoms significantly improved. This reinforces the potential of L-methylfolate to help individuals with certain genetic predispositions, especially when medications interfere with the body's methylation cycle.
Overall, our findings suggest that for some patients, especially those with MTHFR mutations, treating dizziness with folate could be a promising avenue worth exploring further.
After diagnosing her condition, we administered high-dose oral folic acid along with blood transfusions. Remarkably, her haemoglobin significantly improved after three months of treatment, and she returned to her normal activities.
This case highlights that folic acid deficiency can lead to serious anaemia but responds well to treatment.
During his hospital visit, he was diagnosed with cerebral venous thrombosis (CSVT), likely linked to his elevated homocysteine levels—thanks to the vitamin deficiencies. Part of the treatment included folate, which is commonly prescribed alongside B vitamins to help mitigate such issues.
Unfortunately, the case data do not specify the isolated effect of folate on the patient’s dizziness. However, the overall treatment did lead to an improvement in his symptoms after a week.
While we can't definitively attribute his recovery to folate alone, we know it plays a role in maintaining healthy blood levels and could be beneficial for people experiencing dizziness related to vitamin deficiencies. This highlights the importance of a well-rounded approach to treatment that includes adequate vitamin supplementation.
References
- Subair A, Rajkanna J. A Rare Case of Severe Haemolytic Anaemia Due to Folic Acid Deficiency in a Patient with Beta Thalassaemia Trait. Cureus. 2025;17:e79669. doi:10.7759/cureus.79669
- Aikawa R, Jimba M, Nguen KC, Zhao Y, Binns CW, et al. Why do adult women in Vietnam take iron tablets?. BMC Public Health. 2006;6:144.
- Bonding P, Skriver E, Helin P, Qvortrup K. Destructive, granulating lesion in the temporal bone after elevated plasma homocysteine. Otol Neurotol. 2004;25:610.
- Lin SS, Fan IW, Chen CY, Su YJ. A nitrous oxide abuser presenting with cerebral venous thrombosis: A case report. Med Int (Lond). 2022;2:20. doi:10.3892/mi.2022.45
- Trachtman JN, Pagano V. Antifolates and MTHFR. Ther Drug Monit. 2015;37:697. doi:10.1097/FTD.0000000000000215
- Bonding P, Skriver E, Helin P, Qvortrup K. Destructive, granulating lesion in the temporal bone after elevated plasma homocysteine. Otol Neurotol. 2004;25:610.
