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Our findings revealed a surprising link: KTRs with persistent hypercalcemia exhibited higher hemoglobin levels over time—an increase of about 0.76 g/dL per year. This was especially pronounced in men, who showed an increase of 0.80 g/dL per year, compared to a more modest rise of 0.36 g/dL per year in women.
Additionally, our data indicated that these patients had a greater risk of developing post-transplant erythrocytosis, a condition characterized by an elevated red blood cell count. This relationship invites further consideration about the role of calcium levels in blood health, suggesting that rather than causing anemia as might be expected, hypercalcemia may drive erythrocytosis in this unique patient population.
Overall, this study emphasizes the complexity of calcium’s role in post-transplant health and highlights the importance of monitoring hemoglobin levels in KTRs, especially those with persistent hypercalcemia.
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Our findings revealed a surprising link: KTRs with persistent hypercalcemia exhibited higher hemoglobin levels over time—an increase of about 0.76 g/dL per year. This was especially pronounced in men, who showed an increase of 0.80 g/dL per year, compared to a more modest rise of 0.36 g/dL per year in women.
Additionally, our data indicated that these patients had a greater risk of developing post-transplant erythrocytosis, a condition characterized by an elevated red blood cell count. This relationship invites further consideration about the role of calcium levels in blood health, suggesting that rather than causing anemia as might be expected, hypercalcemia may drive erythrocytosis in this unique patient population.
Overall, this study emphasizes the complexity of calcium’s role in post-transplant health and highlights the importance of monitoring hemoglobin levels in KTRs, especially those with persistent hypercalcemia.
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Frequently Asked Questions
Anemia is a medical condition characterized by a deficiency of red blood cells or hemoglobin in the blood, which can result in reduced oxygen flow to the body's organs. The most common type of anemia is iron-deficiency anemia, which occurs when the body does not have enough iron to produce adequate hemoglobin. Other types can arise from chronic diseases, genetic conditions, or a lack of certain vitamins such as B12 or folate. Symptoms often include fatigue, weakness, pale skin, and shortness of breath, particularly during physical activity.
Diagnosing anemia typically involves blood tests to measure levels of red blood cells, hemoglobin concentration, and other related factors. Treatment varies depending on the underlying cause but may include dietary changes, supplements, or medications. In some cases, more serious interventions may be necessary, such as blood transfusions or treatments for associated conditions. If you suspect you have anemia, it's essential to consult a healthcare professional for appropriate evaluation and management.
B5, also known as pantothenic acid, is a vital B vitamin that plays a crucial role in various bodily functions. It is essential for synthesizing coenzyme A, which is key in fatty acid metabolism and the conversion of carbohydrates into energy. Additionally, B5 is involved in the production of red blood cells and helps to maintain healthy skin, hair, and eyes. It can be found in a variety of foods, including meat, fish, dairy products, whole grains, and legumes, making it relatively easy for most people to meet their daily requirements through diet.
While deficiencies in B5 are rare due to its widespread availability in food sources, those who have certain medical conditions, strict vegetarian or vegan diets, or poor nutrition may be more susceptible. Symptoms of a deficiency might include fatigue, irritability, and symptoms related to energy metabolism. Moreover, B5 is also commonly available as a dietary supplement and is often included in multivitamins. However, it's important to consult a healthcare professional before starting any new supplement regimen, particularly if you have underlying health issues or take other medications.
Based on user reviews, results from taking supplements for anemia can vary among individuals, but many users report noticeable improvements within the first few weeks. For instance, one user noted feeling energised and experiencing positive effects on their overall well-being from the first week of taking the supplement, despite dealing with fatigue due to anemia (Read Review). Others have indicated that seeing significant improvements in blood test results can take a bit longer, often several weeks to a few months, especially when combining various B vitamins to address deficiencies (Read Review).
It's important to note that while some users may see immediate benefits, the timeframe for noticeable improvements can depend on individual health factors, the specific supplement being used, and adherence to a regimen. Reviews suggest a three-month supply for optimal results, possibly indicating that that duration is a reasonable expectation for many users to evaluate the supplement's efficacy for anemia (Read Review).
Users have reported a range of improvements in their symptoms after using specific supplements for anemia. Many noted feeling energized and observing positive health changes shortly after beginning their regimens. One user attested to enhanced oxygen intake and improved bowel movements within a week of starting the supplement, even while combating fatigue due to anemia (Read Review). Another mentioned the overall impressive health benefits of vitamin B12 in preventing various health issues related to anemia and chronic conditions (Read Review).
While immediate effects like increased energy were reported, improvements in blood test results were also noted over a longer timeframe for some users. A specific claim shared noted significant enhancements in test results after supplementing with a combination of B vitamins and microelements (Read Review). It's crucial to highlight that individual experiences may vary, and the impact of supplements can depend on personal health circumstances, adherence to a supplement regimen, and the specific nutrients being utilized.
Users have reported positive experiences when combining this supplement with other vitamins and microelements to manage anemia. One user specifically noted that taking pantothenic acid (B5) alongside all B vitamins significantly improved their anemia treatment results, indicating that certain co-factors are essential for optimal effectiveness (Read Review). Additionally, another reviewer experienced substantial improvements in their blood test results after incorporating a mix of this product with other vitamins, suggesting that a well-rounded supplement regimen can enhance overall outcomes in anemia management (Read Review).
Moreover, various users reported improvements in symptoms such as fatigue and increased energy levels by using combinations of beneficial nutrients like B vitamins. For instance, the positive effects on oxygen intake and bowel health were apparent from the first week of use, especially when paired with a complete B vitamin routine (Read Review). Overall, the synergy among these supplements appears to be a common theme in user reviews, providing a sense of empowerment in tackling anemia from multiple angles.
Based on user reviews, there seems to be some consensus on the effectiveness of Vitamin B5 for treating anemia, though specific dosing information is limited. One user reported satisfactory results from taking pantothenic acid (B5) alongside other B vitamins, pointing out that the absence of one co-factor can hinder results in treatment for anemia (Read Review). This indicates that while B5 alone may be beneficial, it is often taken in conjunction with other B vitamins for optimal effectiveness.
Another reviewer noted significant improvements in their anemia and vitamin deficiency levels after using a combination of vitamins, including B5 (Read Review). However, precise dosage recommendations were not specified in the reviews provided. Users seem to appreciate the positive effects of B5 on energy levels and overall well-being, especially when used with a comprehensive vitamin regimen. Therefore, while specific doses weren't mentioned, it appears that a multi-B vitamin approach is favored among users for addressing anemia.
References
- Cojuc-Konigsberg G, Gindl-Bracho A, Linares-Pérez CE, Albarrán-Muñoz S, Reul-Linares E, et al. Effect of persistent hypercalcemia on hemoglobin levels after kidney transplantation. Clin Nephrol. 2025. doi:10.5414/CN111553
