Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8
USERS' SCORE
Good
Based on 12 Reviews
8.1
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Pantothenic Acid (as d-Calcium Pantothenate)
500 mg
10,000%
Calcium (as d-Calcium Pantothenate)
49 mg
4%

Top Medical Research Studies

This study explored how an app-based mindfulness program could help lower anxiety levels in people with HIV who smoke.

Over eight weeks, we followed 16 participants as they tackled 30 mindfulness modules, aiming to reduce their anxiety before quitting smoking.

Encouragingly, we observed reductions in anxiety and an increase in their willingness to quit by the end of the four-week period.

The feedback was positive, indicating that the app was both feasible and well received among participants.
Read More
8
Online CBT improves postpartum anxiety
We examined the impact of a 9-week online group therapy session, led by recovered mothers, on postpartum depression (PPD) and related anxiety. In a randomized controlled trial with 183 participants, those who received the therapy alongside traditional care showed significant improvement in PPD and anxiety levels after 9 weeks.

The results also indicated enhancements in social support and bonding with infants. This unique approach has the potential to broaden the accessibility of essential mental health support for new mothers and their families.
Read More
We explored how acupressure could help reduce fatigue, improve sleep quality, and enhance psychological well-being in patients with end-stage renal disease undergoing hemodialysis.

Conducted in a medical center in Indonesia, this single-blinded randomized controlled trial involved 106 patients, who received either acupressure or a sham treatment for four weeks.

The results showed that acupressure significantly improved fatigue, sleep quality, and even reduced anxiety and depression levels compared to the control group. Overall, no adverse effects were reported, indicating that acupressure can be a beneficial, safe treatment option.
Read More

Most Useful Reviews

9
Alleviates anxiety feelings
After two weeks of regular use to support my adrenal glands, I noticed significant improvements. The uncomfortable sensation in my kidney area vanished, and my overall self-awareness greatly enhanced. Falling asleep became easier, and I forgot about the anxiety I previously experienced in the kidney region. I recommend taking it with your evening meal, as this aligns with the natural secretion of cortisol by the adrenal glands at night.
Read More
9
Calms anxiety and stress
An important component for alleviating anxiety and promoting calmness, this vitamin is also beneficial for beauty.
Read More
9
Removes anxiety effects
Since I began taking this supplement, my anxiety and nocturnal awakenings have significantly improved. I plan to provide further feedback later as I continue its use.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8
  • All Researches
We examined the mental health benefits of forest bathing (FB) in Mediterranean regions during the COVID-19 pandemic. Involving eighty-six adults, we compared FB effects to those of a hiking control group.

Our findings revealed that forest bathing significantly reduces anxiety and enhances mindfulness compared to hiking, exhibiting strong effects. While both activities showed positive impacts on mental well-being, FB outperformed hiking, making it a promising strategy for promoting psychological recovery in these unique environments.

Ultimately, our research suggests that forest bathing could be a valuable tool for fostering well-being as we adapt to life post-pandemic.
Read More
8
Interviews lower anxiety in surgery
We aimed to find out if preoperative educational interviews could help ease anxiety and discomfort for patients undergoing oral and maxillofacial surgery.

This study involved randomizing patients into two groups—one received the interviews, while the other did not. We found that those who had informational chats experienced noticeably lower anxiety levels before surgery.

Additionally, these patients reported less postoperative pain and nausea. Clearly, such preoperative approaches can significantly improve the surgical experience for many patients.
Read More
8
Online CBT improves postpartum anxiety
We examined the impact of a 9-week online group therapy session, led by recovered mothers, on postpartum depression (PPD) and related anxiety. In a randomized controlled trial with 183 participants, those who received the therapy alongside traditional care showed significant improvement in PPD and anxiety levels after 9 weeks.

The results also indicated enhancements in social support and bonding with infants. This unique approach has the potential to broaden the accessibility of essential mental health support for new mothers and their families.
Read More
We explored how acupressure could help reduce fatigue, improve sleep quality, and enhance psychological well-being in patients with end-stage renal disease undergoing hemodialysis.

Conducted in a medical center in Indonesia, this single-blinded randomized controlled trial involved 106 patients, who received either acupressure or a sham treatment for four weeks.

The results showed that acupressure significantly improved fatigue, sleep quality, and even reduced anxiety and depression levels compared to the control group. Overall, no adverse effects were reported, indicating that acupressure can be a beneficial, safe treatment option.
Read More
8
Calcium blockers reduce cocaine withdrawal anxiety
We explored how blocking L-type calcium channels (LTCCs) could influence anxiety-like behaviors during cocaine abstinence in both female and male rats. In this study, rats were trained to self-administer cocaine or saline, followed by a two-week abstinence period. Throughout this withdrawal phase, we examined their behavior using several tests designed to measure anxiety and mood, notably the elevated plus maze and forced swim test, while also checking for changes in their preference for a sweet solution.

Our findings revealed that cocaine-abstinent rats exhibited increased anxiety, as indicated by reduced time spent in open arms of the maze and heightened immobility in the forced swim test. Administering isradipine—a calcium channel blocker—could reverse some anxiety-like behaviors, with varied efficacy based on sex and dosage. For instance, the lower dose effectively reduced anxiety in female rats, while males required a higher dose to obtain similar results. In terms of immobility during stress tests, both sexes benefited from the lower dose of isradipine, while the higher dose affected both groups regardless of their abstinence condition.

This research emphasizes the potential of LTCCs in managing mood-related symptoms linked to cocaine abstinence, though results suggest a more complex relationship that requires further investigation. Overall, our study presents a hopeful look at calcium channel blockade as a possible avenue for treating anxiety disorders that may arise from substance withdrawal.
Read More

User Reviews

USERS' SCORE
Good
Based on 12 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Alleviates anxiety feelings
After two weeks of regular use to support my adrenal glands, I noticed significant improvements. The uncomfortable sensation in my kidney area vanished, and my overall self-awareness greatly enhanced. Falling asleep became easier, and I forgot about the anxiety I previously experienced in the kidney region. I recommend taking it with your evening meal, as this aligns with the natural secretion of cortisol by the adrenal glands at night.
Read More
9
Calms anxiety and stress
An important component for alleviating anxiety and promoting calmness, this vitamin is also beneficial for beauty.
Read More
9
Removes anxiety effects
Since I began taking this supplement, my anxiety and nocturnal awakenings have significantly improved. I plan to provide further feedback later as I continue its use.
Read More
9
Relieves anxiety and stress
I take this at night to address my sleep issues, and it effectively alleviates anxiety and depression. After extended mental strain, it has become a vital support in relieving chronic fatigue. Excellent quality.
Read More
9
Anxiety relief
Been looking at her for a long time. Decided to try this excellent supplement; my anxiety and apathy have vanished.
Read More

Frequently Asked Questions

9
Alleviates anxiety feelings
After two weeks of regular use to support my adrenal glands, I noticed significant improvements. The uncomfortable sensation in my kidney area vanished, and my overall self-awareness greatly enhanced. Falling asleep became easier, and I forgot about the anxiety I previously experienced in the kidney region. I recommend taking it with your evening meal, as this aligns with the natural secretion of cortisol by the adrenal glands at night.
9
Removes anxiety effects
Since I began taking this supplement, my anxiety and nocturnal awakenings have significantly improved. I plan to provide further feedback later as I continue its use.
7.5
Stable mood
The quality of the brand and supplement is high. The ingredient pantethine supports the adrenal glands, leading to a stable nervous system. I have experienced improved sleep along with an antidepressant and anti-anxiety effect.
9
Anxiety relief
Been looking at her for a long time. Decided to try this excellent supplement; my anxiety and apathy have vanished.
9
Calming effects
For adrenal glands, the best vitamin B5 in the form of pantothenic acid is used to support tired adrenal glands; it normalises sleep and alleviates anxiety. Highly recommend it!
0
Increases anxiety issues
Initially purchased for acne, I noticed that higher doses (like 15 pills) are effective. However, I experienced heightened anxiety, along with numbness and tingling when megadosing.
9
Relieves anxiety
I ordered it myself. Vitamin B5 is essential for our adrenal glands. I consume it once a day in the evening. Panthenothenic acid also enhances skin condition. I take it alongside other vitamins. It certainly alleviates anxiety. Definitely, yes! 🙌
8
Calcium blockers reduce cocaine withdrawal anxiety
We explored how blocking L-type calcium channels (LTCCs) could influence anxiety-like behaviors during cocaine abstinence in both female and male rats. In this study, rats were trained to self-administer cocaine or saline, followed by a two-week abstinence period. Throughout this withdrawal phase, we examined their behavior using several tests designed to measure anxiety and mood, notably the elevated plus maze and forced swim test, while also checking for changes in their preference for a sweet solution.

Our findings revealed that cocaine-abstinent rats exhibited increased anxiety, as indicated by reduced time spent in open arms of the maze and heightened immobility in the forced swim test. Administering isradipine—a calcium channel blocker—could reverse some anxiety-like behaviors, with varied efficacy based on sex and dosage. For instance, the lower dose effectively reduced anxiety in female rats, while males required a higher dose to obtain similar results. In terms of immobility during stress tests, both sexes benefited from the lower dose of isradipine, while the higher dose affected both groups regardless of their abstinence condition.

This research emphasizes the potential of LTCCs in managing mood-related symptoms linked to cocaine abstinence, though results suggest a more complex relationship that requires further investigation. Overall, our study presents a hopeful look at calcium channel blockade as a possible avenue for treating anxiety disorders that may arise from substance withdrawal.

References

  1. Kocaturk S, Gur ZB, Gursoytrak B. Can Verbal Interview Decrease Preoperative Anxiety and Postoperative Discomfort in Oral and Maxillofacial Surgery Patients?: A Randomized Clinical Trial. J Oral Maxillofac Surg. 2024;82:1425. 10.1016/j.joms.2024.06.178
  2. Merza D, Amani B, Savoy C, Babiy Z, Bieling PJ, et al. Online peer-delivered group cognitive-behavioral therapy for postpartum depression: A randomized controlled trial. Acta Psychiatr Scand. 2024;150:422. 10.1111/acps.13611
  3. Cioe PA, Sokolovsky AW, Brewer JA, Kahler CW. App-Delivered Mindfulness Training to Reduce Anxiety in People with HIV Who Smoke: A One-Armed Feasibility Trial. Int J Environ Res Public Health. 2023;20. 10.3390/ijerph20064826
  4. Muro A, Mateo C, Parrado E, Subirana-Malaret M, Moya M, et al. Forest bathing and hiking benefits for mental health during the COVID-19 pandemic in Mediterranean regions. Eur J For Res. 2023;142:415. 10.1007/s10342-023-01531-6
  5. Suandika M, Chen SY, Fang JT, Yang SH, Tsai YF, et al. Effect of Acupressure on Fatigue in Hemodialysis Patients: A Single-Blinded Randomized Controlled Trial. J Integr Complement Med. 2023;29:111. 10.1089/jicm.2022.0644
  6. Nunes EJ, Kimble V, Rajadhyaksha AM, Addy NA. L-type calcium channel blockade attenuates the anxiogenic-like effects of cocaine abstinence in female and male rats. Neuroscience. 2025;568:314. 10.1016/j.neuroscience.2025.01.003
image