Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.3
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
L-Carnitine (Carnipure™) (from L-Carnitine Tartrate)
1 g (1,000 mg)
*
Top Medical Research Studies
8
Our research delved into the potential of a new zinc complex combined with acetyl-l-carnitine (ALC) in addressing neuropathy, alongside its antidepressant effects. We found that this novel compound, Zn(ALC)Cl(HO), not only demonstrated significant antidepressant properties but also effective antinociceptive action, which means it helps reduce pain sensitivity.
Specifically, we observed that the Zn(ALC)Cl(HO) complex improved outcomes in models of diabetic neuropathy by preventing the drop in important protective molecules in cells. When we examined how this complex interacts with the nervous system, it was noted that it can cross the blood-brain barrier, offering neuroprotection against harmful conditions like excitotoxicity.
Additionally, the results indicated that under certain inflammatory conditions, the zinc complex counteracts toxic effects from activated astrocytes. These findings suggest that the combined properties of zinc and ALC may make this complex a promising candidate for treating both neuropathy and mood disorders, presenting an exciting avenue for future therapies.
Specifically, we observed that the Zn(ALC)Cl(HO) complex improved outcomes in models of diabetic neuropathy by preventing the drop in important protective molecules in cells. When we examined how this complex interacts with the nervous system, it was noted that it can cross the blood-brain barrier, offering neuroprotection against harmful conditions like excitotoxicity.
Additionally, the results indicated that under certain inflammatory conditions, the zinc complex counteracts toxic effects from activated astrocytes. These findings suggest that the combined properties of zinc and ALC may make this complex a promising candidate for treating both neuropathy and mood disorders, presenting an exciting avenue for future therapies.
Read More
Most Useful Reviews
7.5
Helps during treatment
43 people found this helpful
While hospitalised due to chemotherapy complications, I inquired about alleviating the neuropathy caused by the treatment. Two doctors recommended this supplement to prevent the chemotherapy-induced neuropathy from worsening. While it hasn't completely resolved, it certainly helps.
Read More
7.5
Noticeable improvement
8 people found this helpful
I've just started taking these for neuropathy, and I've noticed an improvement after three weeks. However, the 1000 mg dosage is a bit hard to swallow.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
Our research delved into the potential of a new zinc complex combined with acetyl-l-carnitine (ALC) in addressing neuropathy, alongside its antidepressant effects. We found that this novel compound, Zn(ALC)Cl(HO), not only demonstrated significant antidepressant properties but also effective antinociceptive action, which means it helps reduce pain sensitivity.
Specifically, we observed that the Zn(ALC)Cl(HO) complex improved outcomes in models of diabetic neuropathy by preventing the drop in important protective molecules in cells. When we examined how this complex interacts with the nervous system, it was noted that it can cross the blood-brain barrier, offering neuroprotection against harmful conditions like excitotoxicity.
Additionally, the results indicated that under certain inflammatory conditions, the zinc complex counteracts toxic effects from activated astrocytes. These findings suggest that the combined properties of zinc and ALC may make this complex a promising candidate for treating both neuropathy and mood disorders, presenting an exciting avenue for future therapies.
Specifically, we observed that the Zn(ALC)Cl(HO) complex improved outcomes in models of diabetic neuropathy by preventing the drop in important protective molecules in cells. When we examined how this complex interacts with the nervous system, it was noted that it can cross the blood-brain barrier, offering neuroprotection against harmful conditions like excitotoxicity.
Additionally, the results indicated that under certain inflammatory conditions, the zinc complex counteracts toxic effects from activated astrocytes. These findings suggest that the combined properties of zinc and ALC may make this complex a promising candidate for treating both neuropathy and mood disorders, presenting an exciting avenue for future therapies.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Helps during treatment
43 people found this helpful
While hospitalised due to chemotherapy complications, I inquired about alleviating the neuropathy caused by the treatment. Two doctors recommended this supplement to prevent the chemotherapy-induced neuropathy from worsening. While it hasn't completely resolved, it certainly helps.
Read More
7.5
Noticeable improvement
8 people found this helpful
I've just started taking these for neuropathy, and I've noticed an improvement after three weeks. However, the 1000 mg dosage is a bit hard to swallow.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Caro-RamĂrez JY, Bazán LO, Piro OE, EcheverrĂa GA, Jori K, et al. Exploring Zn(II)-Acetyl l-carnitine complex for simultaneous management of depression, chronic pain, and neuroprotection. J Inorg Biochem. 2025;267:112857. 10.1016/j.jinorgbio.2025.112857
