Supplement Facts
Serving Size: 1 Vegetarian Tablet
Amount Per Serving
%DV
Vitamin C (as Ester-C® Calcium Ascorbate)
1,000 mg (1 g)
1,111%
Calcium (as Ester-C® Calcium Ascorbate)
110 mg
8%
Citrus Bioflavonoids ComplexCitrus Bioflavonoids (Citrus sinensis) (fruit), Sweet Orange, Tangerine, Lime, Lemon, Acerola, Rutin, Hesperidin Complex (Citrus spp.) (fruit), Naturally Occurring Vitamin C Metabolites
200 mg
**

The product is found useful for the following medical conditions

Cold Sores details

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Excellent
Based on 38 Reviews
9.1
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.

Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.

Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.

In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
9.5
Effective cold prevention
Most Useful Review
Very effective; I take it daily and haven’t had a cold in the past six months. It's also great for managing stress and boosting energy.

Cold details

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Excellent
Based on 286 Reviews
9
We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.

But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.

Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.

Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
9.5
Helps colds
Most Useful Review
This vitamin C has facilitated recovery during colds.

Flu details

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.2
USERS' SCORE
Good
Based on 46 Reviews
8.9
We examined the effects of vitamin C on pneumonia caused by the influenza virus, specifically the H1N1 strain, in mice under stress. The study found that when exposed to restraint stress, the mice experienced increased mortality and more severe pneumonia symptoms.

However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.

Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.

Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
10
Effective against flu
Most Useful Review
In my opinion, this is the best remedy! It’s impressive how this allows avoiding flu without excessive medications that merely alleviate symptoms. My husband had a high fever, and after he reluctantly tried it, he was fever-free by the evening and symptom-free by morning. The product truly works; we now take it regularly for prevention, as I genuinely believe it’s worth it for our family's health.

Sore Throat details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.9
10
Eliminates cold symptoms
Most Useful Review
Best Form of Vitamin C! Thanks to these pills, I've forgotten what colds and viruses are. At the first sign of symptoms, I take several capsules, and the following day, there's no trace of sore throat or runny nose.

Athlete’s Foot details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 6 Reviews
8.8
9.5
Rapid response
Most Useful Review
A shock dosage of vitamin C! I take it during fatigue and at the first signs of a virus or cold; it truly puts you on your feet!

Gastritis details

SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.8
USERS' SCORE
Good
Based on 6 Reviews
8.8
We aimed to discover how vitamin C supplementation affects oxidative stress in individuals diagnosed with chronic gastritis. In this study, we looked at 244 Japanese patients suffering from atrophic gastritis. They were randomly assigned to receive either 50 mg or 500 mg of vitamin C every day for five years.

After analyzing the results, we found notable differences between the two groups. The high-dose group experienced a significant decrease in reactive oxygen species (ROS), suggesting that vitamin C may help reduce oxidative stress associated with chronic gastritis. In contrast, the low-dose group reported an increase in ROS levels. These findings prompt further interest in how vitamin C can protect against oxidative stress in similar conditions.

Overall, our study supports the idea that higher doses of vitamin C could have a beneficial effect on oxidative stress, particularly in those dealing with gastritis. This insight opens avenues for considering vitamin C as a potential supportive treatment for managing oxidative stress-related issues in digestive health.
9.5
No heartburn observed
Most Useful Review
The best! I've been purchasing Ester-C with bioflavonoids for years. I have gastritis and increased stomach acidity, but this variant does not cause heartburn, nor does it hurt my stomach. I strongly recommend it. Vitamin C bolsters the immune system and aids in collagen production (beneficial for skin, blood vessels, joints), and it serves as an excellent antioxidant. Plus, the large package containing 1000 mg in each tablet is a significant advantage.

Reflux details

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 9 Reviews
8.8
We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.

We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.

This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
9.5
No reflux issues
Most Useful Review
Great product! The Ester-C formulation does not cause the acid reflux problems that regular Vitamin C does.

Bruise details

SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.2
USERS' SCORE
Good
Based on 5 Reviews
8.7
We explored how vitamin C can impact bruising, particularly in individuals experiencing a deficiency. The research highlighted a case involving an elderly woman who faced challenges such as weakness, easy bruising, and fatigue due to a lack of this vital nutrient.

After beginning treatment with vitamin C supplements, we observed significant improvements in her symptoms, emphasizing the importance of this vitamin in healthier skin and tissue repair. It showcased that scurvy, a condition rooted in vitamin C deficiency, can still occur today, especially in certain at-risk populations.

This case reminds us that while scurvy might seem like a relic of the past, it can still affect modern individuals. Skin issues like easy bruising can sometimes signal deeper dietary concerns that need addressing, especially in older adults.
9.5
Reduction in bruises
Most Useful Review
I believe this Vitamin C is excellent! I noticed a dramatic reduction in my bruises after about two to three weeks of taking one pill daily. I would advise against breaking the pill in half for a lower dose, as it is incredibly difficult to swallow; I tried, and it got stuck in my throat. Swallowing the whole pill is manageable, although it is quite large. Thankfully, it has no taste, which is lovely! Previously, I tried Vitamin C in powder form, and it was rather unpleasant to drink.

Cardiovascular Disease details

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 4 Reviews
8.7
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.

What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.

Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.

Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
9.5
Healthy family benefits
Most Useful Review
Fairy tale This is the best Vitamin C for me, Ester C is one of the best forms, and the quality and results justify the price. My family has used it for years, and it lives up to its promises. We take 3,000mg twice on the first day and 2,000mg twice daily, combined with grapefruit seed extract, colloidal silver, and probiotics. No one in the family has fallen ill for years, not even during seasonal outbreaks. The preventive doses work wonders, and I can vouch for its effectiveness in enhancing health.

Chronic Cough details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.7
9.5
Effective for health
Most Useful Review
This is undoubtedly the best medicine! Admittedly, I lack the detailed knowledge of others who praised it, but I must share my experience. My husband became unwell with a temperature of 38.5 degrees, refusing to drink anything. After some persuasion, he tried the product, and by the evening, his fever had gone. By morning, he felt completely better with no lingering symptoms like a chronic cough. He was pleasantly surprised and now continues to take it willingly. We found the product to be effective and worth the investment, despite initial apprehensions about the price. I’ve even shared it with my family, as it seems to support our health significantly. Dosage varies per individual, but I know what works for us.

Kidney Stones details

SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.1
USERS' SCORE
Good
Based on 3 Reviews
8.7
We examined the relationship between vitamin C intake and the risk of developing kidney stones in a large cohort. This study included a significant number of participants: 156,735 women from the Nurses' Health Studies and 40,536 men from the Health Professionals Follow-up Study.

Our findings revealed that total and supplemental vitamin C intake was linked to a higher risk of kidney stones in men, but there was no such association evident in women. Specifically, among men, those who consumed higher amounts of vitamin C had greater likelihoods of developing stones when compared to those with lower intakes.

However, dietary vitamin C did not show a connection with kidney stones in either men or women. This suggests that while supplements may pose risks for men, dietary sources of vitamin C might not have the same impact. Overall, the study indicates that we should be cautious about high vitamin C supplement consumption, especially for men, while highlighting that dietary intake appears safe.
9.5
Safe for kidneys
Most Useful Review
This vitamin C is superb; Ester-C is the most optimal form, easily digestible. It enhances immunity, acts as a strong antioxidant, and slows the ageing process. It regulates blood pressure, positively impacts joint and cardiovascular diseases, and helps combat stress. It doesn’t irritate the stomach or digestive tract and is safe for the kidneys. The anti-stress and soothing effects are commendable while toning all body systems. It notably aids immunity and speeds recovery from colds, serving as a primary preventative measure.

Ulcer details

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.8
USERS' SCORE
Good
Based on 7 Reviews
8.7
We observed the potential benefits of vitamin C in managing gastric ulcers under conditions of myocardial injury, which was induced using adrenaline in our study. Thirty Wistar rats were carefully divided into five groups, ensuring a control group for comparison.

The rats that received adrenaline alone showed increased gastric secretions and elevated markers related to heart injury. However, those pre-treated with vitamin C experienced a notable reduction in ulcer severity and excessive gastric secretions.

Interestingly, when we administered vitamin C before the adrenaline exposure, we found that it significantly decreased both the volume of gastric juice and total acidity, while also enhancing some protective factors. In essence, our research indicates that vitamin C may play a protective role in gastric health, particularly amid the stressful conditions created by adrenaline.
9.5
Supports immunity
Most Useful Review
This Vitamin C is of excellent quality. Ester-C is absorbed more quickly and does not irritate the gastric mucosa, which is crucial for me as I have an ulcer. I take it to support my immunity, and it’s also vital for collagen production.

Whooping Cough details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.7
9.5
No more coughs
Most Useful Review
I’ve been using this for over a year and it has transformed my health. I no longer suffer from cold-related coughs, and I’ve recommended it to family and friends, especially since the pandemic began. We all take it now.

Allergies details

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 7 Reviews
8.6
We conducted a thorough evaluation of how vitamin C, when combined with pleuran, impacts asthma control and respiratory issues in children suffering from perennial asthma. The study was meticulously designed as a double-blind, placebo-controlled trial involving 230 children aged 7 to 17 years. This means that neither the participants nor the researchers knew who was receiving the active treatment or the placebo, ensuring the findings were reliable.

The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.

While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
8.8
Child's nasal relief
Most Useful Review
Helps improve nasal allergies. The child suffers from long-term nasal allergies, and though quercetin was ineffective, I give him two pills during inflammation. Otherwise, he often experiences a stuffy nose, which is very uncomfortable for him. However, the tablet is rather large, and he struggles to swallow it. I wouldn't recommend this for children.

Anemia details

SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.9
USERS' SCORE
Good
Based on 5 Reviews
8.6
We observed a fascinating phenomenon related to vitamin C and anemia during a series of cases in a prison setting in Ethiopia. Specifically, we examined how scurvy, a disease caused by a lack of vitamin C, contributed to anemia among prisoners.

Our study focused on ten patients who were admitted for treatment, all of whom presented with some form of leg swelling or pain. After administering vitamin C in the form of ascorbic acid, we noted a significant increase in hemoglobin levels, rising from an average of 4.6 to 7.1 g/dL. This improvement indicates that vitamin C may play a crucial role in alleviating some anemia symptoms when the underlying cause is related to dietary deficiencies.

Additionally, through an observational study involving 67 other patients in the same prison, we confirmed that leg swelling and pain were common symptoms among those affected. With consistent therapeutic doses of vitamin C, all patients showed considerable improvement in their conditions.

Thus, we can conclude that vitamin C does seem to have a valuable effect on anemia caused by dietary deficiencies, particularly in high-risk environments like prisons. This finding encourages healthcare providers to remain vigilant about such nutritional deficiencies and highlights the importance of vitamin C in treatment.
9.5
Indicators returned normal
Most Useful Review
I buy this vitamin C, as well as more than one jar, on my doctor's recommendation, alongside other medications such as iron and B complex for anemia. After retaking my tests, all indicators returned to normal, indicating that the treatment is effective. Henceforth, I've started taking it during the autumn-spring period to maintain my immunity.

Autoimmune Disorder details

SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8
USERS' SCORE
Good
Based on 8 Reviews
8.6
We investigated how vitamin C, also known as ascorbic acid, might impact autoimmune disorders like rheumatoid arthritis. Through a study involving a mouse model of collagen-induced arthritis, we administered vitamin C or a placebo solution and observed the effects on the immune response and disease progression.

Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.

Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.

Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
9.5
No stomach issues
Most Useful Review
Not all vitamin C is effective, but this water-soluble form proves ideal. I experience no burning or acid discomfort, even at higher doses, enabling me to avoid illness all winter long!

Bone Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Improves immune system
Most Useful Review
BEST! Ester C is exceptional! Vitamin C is crucial for the body, aiding connective tissue and blood vessels, stimulating blood formation and liver function, regulating blood clotting, and forming bone tissue. It's also an antioxidant that defends against free radicals and is vital for normal bodily function. Ester C, a neutral esterified form, is better tolerated and absorbed compared to traditional ascorbic acid.

Cancer details

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 4 Reviews
8.6
We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1.

By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.

Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
10
Cancer support benefits
Most Useful Review
I consistently assert that these vitamins are essential and should be a staple in every household. My experience with ayherb has proven their worth multiple times. Vitamin C aids the body in producing collagen, assimilating chondroprotectors, and fighting free radicals, while enhancing immunity. It protects against winter colds and summer oedema. The Nobel laureate Linus Pauling demonstrated its ability to destroy cancer stem cells. Caring for loved ones includes ensuring they receive these essential vitamins. Wishing you and your family good health.

Food Poisoning details

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 2 Reviews
8.6
To explore the effects of vitamin C on food poisoning caused by Campylobacter jejuni, we conducted a study using mice specifically bred to develop a condition similar to human campylobacteriosis. Mice were treated with synthetic vitamin C in their drinking water starting four days before they were infected with the bacteria. Our goal was to see if this treatment could lessen the severity of their symptoms.

Over the course of our research, we found that the mice receiving vitamin C had lower levels of the bacteria in their intestines. They also experienced less severe inflammation and other symptoms associated with infections. Interestingly, the benefits of vitamin C extended beyond just the intestines; we noticed reduced inflammatory responses in other organs such as the liver, kidneys, and lungs.

This suggests that vitamin C could be a promising option for both preventing and treating acute campylobacteriosis. Our findings highlight the potential health benefits of this vitamin and its role in managing foodborne illnesses like those triggered by Campylobacter jejuni.
9.5
Quick recovery
Most Useful Review
Vitamin C is essential for our body but is not naturally produced, requiring us to obtain it from food. To support our health in winter, my whole family regularly consumes vitamin C. During a cold, we took a double dose, leading to a swift recovery, thus confirming the drug's effectiveness.

Headache details

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 4 Reviews
8.6
We aimed to understand how dietary vitamin C affects migraines by analyzing data from the National Health and Nutrition Examination Survey, conducted from 1999 to 2004. In this survey, we identified adults who reported experiencing severe headaches or migraines over the past three months.

Our findings were quite revealing. Out of 4,101 participants, 702 individuals reported having a migraine, which represents about 17% of the group. We discovered an interesting trend: higher dietary vitamin C intake seemed to correlate with a lower likelihood of experiencing migraines. Specifically, participants with the highest vitamin C intake had a 36% reduced odds of suffering from migraines compared to those with the lowest intake.

We employed various statistical methods to confirm our results, including logistic regression and restricted cubic spline regression, which showed a clear linear relationship between vitamin C intake and the frequency of migraines.

Overall, this study suggests that increasing our dietary vitamin C might help minimize migraines, which is promising news for those who suffer from these intense headaches. However, as with all studies, further research is necessary to solidify these findings and fully understand the relationship between vitamin C and headache relief.
10
Eliminates fatigue
Most Useful Review
I really love this vitamin C, especially in this dosage. With my chronic gastritis, it's one of the few vitamins that doesn’t upset my stomach. Previously, I experienced fatigue, drowsiness, weakness, and headaches, but now I have none of that. I'm hesitant to recommend it too enthusiastically, but I genuinely want everyone to benefit from this excellent vitamin C.

Irritable Bowel Syndrome details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Great for IBS
Most Useful Review
Excellent! Good news for irritable bowel. I give it to my husband.

Nausea details

SCIENTIFIC SCORE
Very Likely Ineffective
Based on 1 Research
2
USERS' SCORE
Good
Based on 2 Reviews
8.6
We explored the effects of vitamin C as a treatment for nausea and vomiting in pregnancy, also known as emesis gravidarum. Our study involved 111 participants, who were given either vitamin C-containing chewing gum, a placebo, or no treatment at all. We monitored them over two follow-up visits in early pregnancy to assess their symptoms.

While we measured various factors that could influence nausea—including hormone levels like hCG and DAO—our findings showed that the chewing gum did not effectively reduce nausea symptoms compared to the placebo or no treatment. Specifically, the vitamin C gum was not associated with any significant alleviation of nausea or vomiting.

Interestingly, we found that elevated levels of hCG were linked to increased nausea severity. In contrast, higher levels of DAO appeared to have a protective effect against symptoms. Additionally, elevated thyroxine and pyridoxine levels correlated with worsened nausea.

Overall, while vitamin C is often highlighted for its health benefits, our results suggest it does not play a significant role in treating nausea during pregnancy. This study highlights the complexities behind nausea in pregnancy, indicating that further research is necessary to uncover effective treatment options.
9.5
No nausea experienced
Most Useful Review
Excellent! This vitamin C does not induce nausea.

Rash details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Effective for herpes
Most Useful Review
Works well without side effects. An excellent form and dosage of vitamin C with bioflavonoids, it's a less expensive alternative to Esther-S from Solgar. The dryness and brittleness of my skin, particularly in cold weather, have vanished. Herpes rashes have disappeared along with several other beneficial effects. I take 1 gram daily for extended periods. During times of ARV/Influenza/Covid, I increase it to 5 grams per day based on my weight (75 kg). After an overdose, I experienced a taste of ascorbic acid and temporary indigestion, but pausing the doses resolved everything within a day.

Sleep Apnea details

SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.6
We evaluated how vitamin C might improve endothelial function in patients with obstructive sleep apnea (OSA). In our study, we compared 10 individuals with untreated OSA to 10 matched control subjects without sleep issues. We measured how well blood vessels reacted to increased blood flow, known as flow-mediated dilation (FMD), using ultrasound before and after administering vitamin C.

Our findings revealed a significant difference: baseline FMD was lower in OSA patients compared to the control group. However, after an intravenous injection of vitamin C, the FMD in OSA patients improved dramatically, reaching levels similar to those seen in the healthy controls. Interestingly, vasoreactivity in the control subjects remained unchanged.

These results suggest that oxidative stress might be a key factor contributing to the endothelial dysfunction experienced by individuals with OSA. The positive response to vitamin C opens up exciting possibilities for exploring antioxidant treatments in managing cardiovascular issues related to OSA.
8.8
Effective night use
Most Useful Review
I was advised to take this vitamin C at night, so it works throughout my sleep. My boyfriend appreciates this great product.

Blood Clot details

SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.7
USERS' SCORE
Good
Based on 2 Reviews
8.5
We sought to understand how ascorbic acid, commonly known as vitamin C, impacts blood clotting during living donor liver transplantation (LDLT). In our study, we analyzed blood samples from 21 recipients before and after their surgeries.

We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.

Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.

This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
8
Gentle on intestines
Most Useful Review
My favourite vitamin C! It’s excellent—doesn't cause harm. It contains bioflavonoids that improve absorption and positively impact blood vessels. The tablets are quite large, but none of my family has trouble swallowing them; however, they can be crushed if necessary. It does not irritate the intestines, which is great for those with gastrointestinal issues.

Cough details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.5
9.5
Coughs reduced significantly
Most Useful Review
I love this product! I've been using it for over a year, and it works wonders for me. Compared to previous years, I no longer experience coughs or colds. The entire family takes this, and I’ve recommended it to friends, especially during the pandemic. We are all still using it.

Diarrhea details

SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.5
USERS' SCORE
Good
Based on 5 Reviews
8.5
We investigated how adding vitamin C to milk influences the growth and health of young calves, particularly those experiencing diarrhea. The study involved 48 Holstein calves, which were sorted into two groups based on their health status: healthy calves and those with diarrhea. Each calf was fed the same amount of pasteurized milk and monitored until they reached 74 days of age.

Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.

The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
9.5
No stomach issues
Most Useful Review
This Vitamin C version tastes great and does not cause stomach issues. It's much better than ascorbic acid due to its complete vitamin C complex and neutral acidity, so I don’t experience diarrhea at all. I'm feeling fantastic!

Liver Disease details

SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.9
USERS' SCORE
Good
Based on 5 Reviews
8.5
We evaluated how vitamin C, also known as ascorbic acid, can help protect the liver during procedures that temporarily cut off blood flow—a process known as ischaemia followed by reperfusion. In this study, we used thirty-six male Wistar rats, split into control groups and experimental ones. Each group received the same total dose of vitamin C, administered at different times: either before the ischaemia, before the reperfusion, or both.

Our findings showed that the animals given vitamin C before both the ischaemia and reperfusion had improved outcomes. They had lower levels of liver enzymes, indicating less liver damage, and showed reduced inflammation. Additionally, their portal blood flow was better when compared to the other groups. Overall, our results suggest that administering vitamin C at specific times can significantly reduce liver injury associated with ischaemia-reperfusion.

This study highlights the potential of vitamin C as a protective agent in situations where liver damage is a concern during surgeries or treatments involving blood flow disruption.
8.8
Strengthens immunity
Most Useful Review
This product, with added bioflavonoids, is effective. It significantly reduces the duration and severity of illness, making it a worthwhile addition to my health routine!

Pelvic Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.5
8.3
Pain significantly reduced
Most Useful Review
Over the past six months, my pelvic pain has been significantly reduced, and I truly believe that this product supports a robust immune system. The packaging is compact, the quantity is generous, and the pills have no unusual odour. One bottle is enough for half a year—do the maths!

Chronic Fatigue Syndrome details

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
USERS' SCORE
Good
Based on 5 Reviews
8.4
We examined how a combination of megadose vitamin C infusions and other treatments might help manage chronic fatigue syndrome, particularly in the context of interstitial pneumonia. Our findings were based on nearly a decade of treating patients, allowing us to gather valuable insights.

We observed that the long-term use of this treatment system significantly reduced the risk of pneumonia recurrence. It also appeared to help prevent the emergence of certain cancers in older patients suffering from interstitial pneumonia. Surprisingly, we found a link between interstitial pneumonia and an increased risk of depression, likely driven by prolonged glucocorticoid use.

While some patients showed promise under this treatment, those battling both interstitial pneumonia and depression responded less favorably. We suggested that increasing the amount of dehydroepiandrosterone in the treatment could be beneficial. Throughout our experience, we noted that the characteristics of chronic fatigue syndrome align closely with those of interstitial pneumonia, arguing against the notion that they should be viewed as separate conditions.

Overall, our approach not only alleviated inflammation but did not suppress the fibrotic processes in the long run. We made modifications to the treatment to lower the risks of vascular complications. The main strength of our treatment lies in creating a hormonal environment that helps tackle immune deficiencies using vitamin C, which faces lower resistance in the body compared to steroid treatments.
9.5
Eliminates fatigue effectively
Most Useful Review
This supplement significantly improves my health, immunity, and overall mood. After buying it out of curiosity, I discovered it effectively boosts my energy and eliminates fatigue caused by long flights and stress. I highly recommend this brand!

Heartburn details

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 19 Reviews
8.4
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
9.5
No gastrointestinal issues
Most Useful Review
I experienced heartburn symptoms with other vitamin C products, but this one causes no gastrointestinal issues, which is why I like it.

Influenza details

SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
USERS' SCORE
Good
Based on 3 Reviews
8.4
We explored the relationship between vitamin C and influenza, delving into various studies conducted from 2000 to June 2021. In our analysis of the research, we found eleven studies that specifically examined the effects of vitamin C on influenza.

While some of these studies reported positive outcomes, we should note that the isolated benefits of vitamin C can be hard to determine. This is primarily because some studies included additional treatments, making it difficult to draw definitive conclusions about vitamin C alone.

Overall, we observed that while there is some interest and preliminary evidence regarding the efficacy of vitamin C in preventing or treating influenza, its stand-alone effectiveness remains somewhat unclear.

Continued research should help clarify how much vitamin C can truly contribute to combating influenza.
9.5
Speeds recovery
Most Useful Review
This product is useful and helps combat influenza. It improves resistance to respiratory illnesses and alleviates sore throats, thereby speeding up recovery from influenza.
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