5/19/2025
Last update
5/19/2025
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.8
USERS' SCORE
Moderately Good
Based on 20 Reviews
7.6
Supplement Facts
Serving Size: One (1) Capsule
Amount Per Serving
%DV
Calories
0
Total Carbohydrate
0 g
0%**
Total Sugars
0 g
†
Incl. 0 g Added Sugars
0%**
Intelliflora™ Blend:
150 mg5 billion CFUs
Lactobacillus crispatus LBV 88
†
Lactobacillus rhamnosus LBV 96
†
Lactobacillus gasseri LBV 150N
†
Lactobacillus jensenii LBV 116
†
Top Medical Research Studies
9
We investigated the effects of Limosilactobacillus fermentum (L. fermentum) KBL674 on vaginal candidiasis in a mouse model. This strain inhibited the growth of Candida albicans and significantly decreased infection symptoms. Notably, the oral intake of L. fermentum KBL674 influenced both vaginal and gut microbiome health, promoting beneficial bacteria that seemed to correlate with reduced C. albicans levels. Thus, L. fermentum KBL674 shows promise for managing vaginal candidiasis by enhancing gut microbiome diversity and lowering fungal burden.
9
We conducted a rigorous study to investigate the impact of lactobacillus probiotics on pregnant women suffering from vaginal candidiasis. In this double-blind, placebo-controlled trial involving 78 participants, we administered a probiotic for eight weeks.
Our results highlighted significant benefits, with the probiotics maintaining microbiota stability in the vagina and gut, unlike the placebo group. Participants taking probiotics showed less variation in their microbiota, which is crucial for overall health. While the treatment showed promise in preserving microbiota composition, individual experiences may vary.
Our results highlighted significant benefits, with the probiotics maintaining microbiota stability in the vagina and gut, unlike the placebo group. Participants taking probiotics showed less variation in their microbiota, which is crucial for overall health. While the treatment showed promise in preserving microbiota composition, individual experiences may vary.
4
Lactobacillus shows promise for candidiasis
We assessed how well Lactobacillus plantarum P 17630 works against vaginal candidiasis compared to traditional antifungal treatments like miconazole. In a controlled trial, women with candidiasis took either Lactobacillus capsules or miconazole capsules for several days. Results showed that both treatments reduced vaginitis symptoms over time, with no significant differences. Importantly, Lactobacillus treatment did not lead to any adverse effects and may foster healthier vaginal flora in the long run, potentially decreasing recurring infections.
Most Useful Reviews
9
Comfort in intimacy
11 people found this helpful
My wife often suffers from thrush, so I decided to order these probiotics for her. After starting the course, she noticed a significant improvement in comfort in the intimate area, and no longer experiences the discomfort she had. She has remarked positively on the effect, and even a month after completing the treatment, the results are still evident. She believes these are excellent probiotics.
0
No improvement noticed
4 people found this helpful
I bought these probiotics randomly after reading various reviews. During my fifth month of pregnancy, I struggled with thrush, but they didn’t help me at all. Despite claims of clinically proven results, I experienced another bout of thrush, and I did not feel any improvement.
9
Highly efficient
1 people found this helpful
It's the first time I've faced a candida issue. After taking this probiotic for a few days, I've felt a great deal of relief, and it’s very effective. It has been regarded as a daily health product.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.8
- All Researches
9.5
This study looked at Lactobacillus gasseri VHProbi E09, a strain shown to effectively inhibit harmful bacteria like Gardnerella vaginalis and Candida albicans, key players in vaginitis. We found that this strain could cut the growth of both pathogens by an impressive 99%, while also preventing their attachment to vaginal cells.
What’s exciting is the potential of L. gasseri VHProbi E09 as a probiotic for improving vaginal health, either taken orally or applied directly. However, more research is needed to fully explore its effects and effectiveness in restoring balance in the vaginal ecosystem.
What’s exciting is the potential of L. gasseri VHProbi E09 as a probiotic for improving vaginal health, either taken orally or applied directly. However, more research is needed to fully explore its effects and effectiveness in restoring balance in the vaginal ecosystem.
9
Identified lactobacillus metabolites inhibit Candida
Through innovative techniques like genome-scale metabolic modeling and metagenomic sequencing, we discovered the role of specific lactobacillus strains in combating vulvovaginal candidiasis (VVC).
Our analysis of 159 strains showed that many have inhibitory effects on Candida, altering its metabolism through key metabolites like L-lactate and formate. Interestingly, we found a positive link between the presence of these beneficial strains and lower Candida levels in vaginal samples.
This research informs future strategies focused on enhancing vaginal health by utilizing these powerful strains and their metabolites to hinder candidiasis.
Our analysis of 159 strains showed that many have inhibitory effects on Candida, altering its metabolism through key metabolites like L-lactate and formate. Interestingly, we found a positive link between the presence of these beneficial strains and lower Candida levels in vaginal samples.
This research informs future strategies focused on enhancing vaginal health by utilizing these powerful strains and their metabolites to hinder candidiasis.
9
We investigated the potential of a newly isolated probiotic, AJCR4, to combat oral candidiasis, a common infection, particularly among immunocompromised individuals. AJCR4 showed strong antifungal effects against both free and biofilm forms of Candida, with impressive results in reducing viable cells in lab tests. In specific biofilms, we observed over 2-log reductions in cell counts. This promising performance suggests that AJCR4 could serve as an effective alternative strategy for treating difficult oral candidiasis cases, especially recurrent infections.
9
We investigated the effects of a novel fermentation broth called VAGINNE on vulvovaginal candidiasis (VVC), a common condition affecting many women. Using a mouse model, we found that VAGINNE not only boosted beneficial bacteria but also suppressed the growth of Candida, promoting a healthier vaginal environment.
Additionally, VAGINNE significantly decreased inflammation markers, which is essential for tissue health. This promising approach suggests VAGINNE could be a valuable alternative to traditional antifungals, especially for women facing drug resistance or side effects from standard treatments.
Additionally, VAGINNE significantly decreased inflammation markers, which is essential for tissue health. This promising approach suggests VAGINNE could be a valuable alternative to traditional antifungals, especially for women facing drug resistance or side effects from standard treatments.
9
We explored how combining oral probiotics with standard antifungal treatment affects vulvovaginal candidiasis (VVC). In a randomized controlled trial involving 60 patients, we compared results between those receiving antifungal medication alone and those receiving it alongside probiotics.
The results were promising! Participants who took probiotics showed better clinical and mycological outcomes, along with a reduced rate of relapse compared to those on antifungal treatment alone. This suggests that probiotics may be a valuable addition to VVC management.
The results were promising! Participants who took probiotics showed better clinical and mycological outcomes, along with a reduced rate of relapse compared to those on antifungal treatment alone. This suggests that probiotics may be a valuable addition to VVC management.
User Reviews
USERS' SCORE
Moderately Good
Based on 20 Reviews
7.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Comfort in intimacy
11 people found this helpful
My wife often suffers from thrush, so I decided to order these probiotics for her. After starting the course, she noticed a significant improvement in comfort in the intimate area, and no longer experiences the discomfort she had. She has remarked positively on the effect, and even a month after completing the treatment, the results are still evident. She believes these are excellent probiotics.
0
No improvement noticed
4 people found this helpful
I bought these probiotics randomly after reading various reviews. During my fifth month of pregnancy, I struggled with thrush, but they didn’t help me at all. Despite claims of clinically proven results, I experienced another bout of thrush, and I did not feel any improvement.
9
Highly efficient
1 people found this helpful
It's the first time I've faced a candida issue. After taking this probiotic for a few days, I've felt a great deal of relief, and it’s very effective. It has been regarded as a daily health product.
10
Wonderful results
Lo amoo! I have been using this for three months, and it is truly wonderful. I highly recommend it. I suffered from candida but have not had any outbreaks. I am thrilled.
9
Effective for chronic thrush
Fantastic! I used these probiotics for chronic thrush along with AZO boric acid suppositories and dual yeast treatments. I feel immensely better now that my pH is restored, and my intimate health has significantly improved. I finally feel healthy and confident again. I highly recommend AZO for your intimate concerns!
Frequently Asked Questions
9
Highly efficient
1 people found this helpful
It's the first time I've faced a candida issue. After taking this probiotic for a few days, I've felt a great deal of relief, and it’s very effective. It has been regarded as a daily health product.
10
Wonderful results
Lo amoo! I have been using this for three months, and it is truly wonderful. I highly recommend it. I suffered from candida but have not had any outbreaks. I am thrilled.
0
No improvement noticed
4 people found this helpful
I bought these probiotics randomly after reading various reviews. During my fifth month of pregnancy, I struggled with thrush, but they didn’t help me at all. Despite claims of clinically proven results, I experienced another bout of thrush, and I did not feel any improvement.
9
Comfort in intimacy
11 people found this helpful
My wife often suffers from thrush, so I decided to order these probiotics for her. After starting the course, she noticed a significant improvement in comfort in the intimate area, and no longer experiences the discomfort she had. She has remarked positively on the effect, and even a month after completing the treatment, the results are still evident. She believes these are excellent probiotics.
6
Works well with antibiotics
I always keep these probiotics in my first aid kit. I begin taking them when prescribed antibiotics as they work excellently. I also took them for mild thrush. Unlike other probiotics I've tried, this one effectively normalised my bowel movements, reduced bloating, and regulated my female microflora. I will definitely repurchase.
2
Did not help
It is very expensive, but unfortunately, it didn’t assist with my candida. I took it for about half a year without any success.
9
Effective for chronic thrush
Fantastic! I used these probiotics for chronic thrush along with AZO boric acid suppositories and dual yeast treatments. I feel immensely better now that my pH is restored, and my intimate health has significantly improved. I finally feel healthy and confident again. I highly recommend AZO for your intimate concerns!
9
Effective with additional treatment
Great probiotic! We acquired it based on our doctor's recommendation and used it alongside suppositories and tablets from the same brand to combat thrush effectively.
7.5
Preventative post-treatment use
I used these probiotics after undergoing anti-candidal treatment to prevent a relapse. The results were wholly satisfying, but I should mention that following an anti-candida diet is also key for optimal outcomes.
4
Ineffective for me
The effect has been average for me. I purchased a treatment for candida, but it still keeps relapsing. Perhaps this product is not effective for me, so I will seek alternatives.
7.5
Recent tests improved
2 people found this helpful
I appreciated the convenience of one capsule per day, which I used while addressing candida thrush. My recent tests have indicated good results. I suggest giving it a try, and I kept it refrigerated as well.
7.5
Vaginal health support
This aids women’s vaginal health effectively, as it can prevent candida. I take one pill daily and two during sensitive periods, and everything improves soon. I recommend it.
7.5
Partially helpful
1 people found this helpful
I chose this probiotic for systemic candidiasis therapy due to its lactobacilli composition. Initially, there were no changes, but then I did experience painful discharges, which resolved without additional treatment. While not containing the daily 50 billion lactobacilli I believe necessary, it did provide partial help. The capsules are small and easy to swallow. I intend to use them for at least another 3-4 months.
9
We investigated the effects of Limosilactobacillus fermentum (L. fermentum) KBL674 on vaginal candidiasis in a mouse model. This strain inhibited the growth of Candida albicans and significantly decreased infection symptoms. Notably, the oral intake of L. fermentum KBL674 influenced both vaginal and gut microbiome health, promoting beneficial bacteria that seemed to correlate with reduced C. albicans levels. Thus, L. fermentum KBL674 shows promise for managing vaginal candidiasis by enhancing gut microbiome diversity and lowering fungal burden.
7
Probiotics show promise but variable
We explored the effectiveness of probiotics, especially certain lactobacillus strains, in treating vulvovaginal candidiasis (VVC) and bacterial vaginosis (BV). By reviewing 11 high-quality randomized controlled trials, we found that probiotics could help restore a healthy vaginal microbiota and showed promising clinical outcomes.
However, the results varied across studies, signaling that more research is necessary to fully understand their benefits in treating these infections.
However, the results varied across studies, signaling that more research is necessary to fully understand their benefits in treating these infections.
9
We explored how combining oral probiotics with standard antifungal treatment affects vulvovaginal candidiasis (VVC). In a randomized controlled trial involving 60 patients, we compared results between those receiving antifungal medication alone and those receiving it alongside probiotics.
The results were promising! Participants who took probiotics showed better clinical and mycological outcomes, along with a reduced rate of relapse compared to those on antifungal treatment alone. This suggests that probiotics may be a valuable addition to VVC management.
The results were promising! Participants who took probiotics showed better clinical and mycological outcomes, along with a reduced rate of relapse compared to those on antifungal treatment alone. This suggests that probiotics may be a valuable addition to VVC management.
9
LM1215 shows promise for VVC prevention
We observed three specific strains of Lactobacillus, namely LM1203, LM1209, and LM1215, that displayed promising results in inhibiting vulvovaginal candidiasis (VVC). Isolated from healthy women, these strains significantly reduced the growth of harmful pathogens.
In addition, LM1215 showed remarkable ability to disrupt biofilms and induce cellular damage against these pathogens. Our findings suggest that LM1215 is not only effective but also safe, positioning it as a viable probiotic option for preventing VVC and bacterial vaginosis.
In addition, LM1215 showed remarkable ability to disrupt biofilms and induce cellular damage against these pathogens. Our findings suggest that LM1215 is not only effective but also safe, positioning it as a viable probiotic option for preventing VVC and bacterial vaginosis.
References
- Hu T, Meng Y, Zhao C, Sheng D, Yang S, et al. Genome-scale metabolic modeling reveals specific vaginal strains and their metabolites as key inhibitors of . Microbiol Spectr. 2025. 10.1128/spectrum.02984-24
- Nachum Z, Suleiman A, Colodner R, Battino S, Wattad M, et al. Oral Probiotics to Prevent Recurrent Vulvovaginal Infections During Pregnancy-Multicenter Double-Blind, Randomized, Placebo-Controlled Trial. Nutrients. 2025;17. 10.3390/nu17030460
- Rajão A, Silva JPN, Almeida-Nunes DL, Rompante P, Rodrigues CF, et al. AJCR4: A Potential Probiotic in the Fight Against Oral spp. Biofilms. Int J Mol Sci. 2025;26. 10.3390/ijms26020638
- Horng HC, Xu JW, Kuo YS, Chen YS, Chiu YH, et al. Dual Mechanisms of Action: Anti-Candida and Anti-Inflammatory Potential of Fermentation Broth in Treating Vulvovaginal Candidiasis. J Fungi (Basel). 2024;11. 10.3390/jof11010018
- Thekho AJ, Mendiratta V, Garg T, Kaur R, Yadav V. Role of Probiotic in Vulvovaginal Candidiasis: A Randomised Controlled Non-blinded Trial from India. Indian J Dermatol. 2024;69:422. 10.4103/ijd.ijd_193_24
- Bae WY, Lee YJ, Jo S, Shin SL, Kim TR, et al. Effects of LM1215 on and . Yonsei Med J. 2024;65:727. 10.3349/ymj.2023.0490
- Jang SJ, Jo EJ, Lee C, Cho BR, Shin YJ, et al. Limosilactobacillus fermentum KBL674 Alleviates Vaginal Candidiasis. Probiotics Antimicrob Proteins. 2024. 10.1007/s12602-024-10403-3
- Ferreira RLPS, Nova BGV, Carmo MS, Abreu AG. Mechanisms of action of Lactobacillus spp. in the treatment of oral candidiasis. Braz J Biol. 2024;84:e282609. 10.1590/1519-6984.282609
- Vazquez-Munoz R, Thompson A, Sobue T, Dongari-Bagtzoglou A. is a dominant in the murine oral mucosa and has chitinase activity that compromises fungal cell wall integrity. mBio. 2024;15:e0241624. 10.1128/mbio.02416-24
- Zuñiga Vinueza AM. Probiotics for the Prevention of Vaginal Infections: A Systematic Review. Cureus. 2024;16:e64473. 10.7759/cureus.64473
- Zhang J, Li K, Cao T, Duan Z. Characterization of a Lactobacillus gasseri strain as a probiotic for female vaginitis. Sci Rep. 2024;14:14426. 10.1038/s41598-024-65550-y
- Elsayes SA, El Attar MS, ElHadary A, Aboulela AG, Essawy MM, et al. Antimycotic prophylaxis with multispecies probiotics against oral candidiasis in new complete denture wearers: A randomized clinical trial. J Prosthet Dent. 2024. 10.1016/j.prosdent.2024.05.018
- Zahedifard T, Khadivzadeh T, Rakhshkhorshid M. The Role of Probiotics in the Treatment of Vulvovaginal Candidiasis: A Systematic Review and Meta-Analysis. Ethiop J Health Sci. 2023;33:881. 10.4314/ejhs.v33i5.18
- Ang XY, Roslan NS, Ahmad N, Yusof SM, Abdullah N, et al. Lactobacillus probiotics restore vaginal and gut microbiota of pregnant women with vaginal candidiasis. Benef Microbes. 2023;14:421. 10.1163/18762891-20220103
- Bertarello C, Savio D, Morelli L, Bouzalov S, Davidova D, et al. Efficacy and safety of Lactobacillus plantarum P 17630 strain soft vaginal capsule in vaginal candidiasis: a randomized non-inferiority clinical trial. Eur Rev Med Pharmacol Sci. 2024;28:384. 10.26355/eurrev_202401_34927
- Faustino M, Pereira JO, Pereira AM, Oliveira AS, Ferreira CMH, et al. Vaginal prevention of Candida albicans: synergistic effect of lactobacilli and mannan oligosaccharides (MOS). Appl Microbiol Biotechnol. 2024;108:73. 10.1007/s00253-023-12909-2
