Best Naturals Alpha Lipoic Acid

Supplement Facts

Serving Size: 1 Capsule

Serving Per Container: 120

Amount Per Serving

%DV

Alpha Lipoic Acid

600 mg

The product is found useful for the following medical conditions

We conducted a double-blind, placebo-controlled study involving 52 patients with diabetic neuropathy on gabapentin or pregabalin to explore the effects of alpha-lipoic acid (ALA). Over 12 weeks, we found that ALA significantly improved vibration perception threshold and secondary symptoms like overall quality of life, oxidative, and inflammatory markers.

Importantly, participants reported no serious side effects, highlighting ALA’s potential as a safe option for managing diabetic neuropathy. These findings suggest ALA can effectively mitigate symptoms associated with chronic hyperglycemia.

Reduced pain medication use

Most Useful Review

15 people found this helpful

My neurologist recommended this for peripheral neuropathy. After a month, I was able to cut my pain medication use by over half. I switched brands and had a reaction, but returned to this one with no problems. It’s not a miracle cure, but it has helped me more than any prescription meds I've tried over 20 years. Major decrease in symptoms.

Diabetes details

SCIENTIFIC SCORE

Possibly Effective

Based on 3 Researches

Alpha-lipoic acid enhances wound healing

Zoheir KMA, Ali NI, Ashour AE, Kishta MS, Othman SI, et al. Lipoic acid improves wound healing through its immunomodulatory and anti-inflammatory effects in a diabetic mouse model. J Diabetes Metab Disord. 2025;24:56. doi:10.1007/s40200-025-01559-y

We aimed to understand how alpha-lipoic acid (LA) affects wound healing in diabetic conditions. The study involved five groups of mice: healthy controls, wounded healthy mice, wounded diabetic mice, and two groups of wounded diabetic mice treated with different doses of LA for 14 days.

Our findings indicated that LA plays a significant role in improving the healing process. It works by balancing the levels of anti-inflammatory and pro-inflammatory factors that are essential for wound recovery. Specifically, we saw effects on various immune cell types that are vital for healing, indicating that LA may help to enhance recovery in diabetic wounds.

This study highlights the potential of LA as a supportive treatment option for wound healing in diabetic patients, ultimately aiming to reduce the risk of infections and improve overall recovery from injuries.

Manages neuropathy

Most Useful Review

2 people found this helpful

I purchased this for my 87-year-old mother with diabetes. Doctors recommended alpha-lipoic acid to help her manage diabetic neuropathy. I found it much cheaper to buy online. It significantly alleviates her symptoms and helps lower her blood sugar levels, which may require adjustment of her medications.

Cancer details

SCIENTIFIC SCORE

Likely Very Effective

Alpha-lipoic acid aids recovery

Sgaramella LI, Pasculli A, Moschetta M, Puntillo F, Dicillo P, et al. Randomized controlled trial of bromelain and alpha-lipoic acid in breast conservative surgery. Sci Rep. 2025;15:4899. doi:10.1038/s41598-025-86651-2

We conducted a thorough analysis to determine how alpha-lipoic acid, in combination with other supplements, affects early complications like edema and seroma following breast-conserving surgery (BCS). Our study was structured as a double-blind, randomized, placebo-controlled trial involving 114 participants over a span of three years.

Participants were divided into three groups, with one group receiving a mix of Casperome™-Boswellia Phytosome and bromelain along with alpha-lipoic acid, while the other groups received either bromelain with a placebo or just a placebo. Over a period of 30 days, we gathered data on the effectiveness of these treatments.

Our findings revealed that the combination of bromelain and alpha-lipoic acid significantly reduced the incidence of edema and seroma compared to the placebo. Specifically, after one month, we observed marked improvements in patients who received the active treatment. This research highlights the potential therapeutic benefits of alpha-lipoic acid, especially when used with other agents, in managing early complications that can follow breast surgery. Although it’s important to note that the specific isolating effects of alpha-lipoic acid on its own were challenging to determine, the results offer a promising glimpse into its use in surgical recovery.

7.5

Aids treatment hopes

Most Useful Review

For my mum's cancer treatment, I sincerely hope it helps. I am taking it consistently.

Liver Disease details

SCIENTIFIC SCORE

Moderately Effective

Based on 2 Researches

Alpha-lipoic acid protects liver health

Zhao Y, Guo M, Pei T, Shang C, Chen Y, et al. α-Lipoic Acid Ameliorates Arsenic-Induced Lipid Disorders by Promoting Peroxisomal β-Oxidation and Reducing Lipophagy in Chicken Hepatocyte. Adv Sci (Weinh). 2025. doi:10.1002/advs.202413255

We explored the protective effects of alpha-lipoic acid (LA) against liver damage caused by arsenic, a well-known environmental toxin. In our examination, we uncovered the mechanisms through which arsenic harms the liver, including its ability to induce autophagy, apoptosis, and oxidative stress, as well as disrupt lipid metabolism.

Our findings revealed that arsenic negatively impacts liver function primarily by reducing the expression of SIRT1, damaging mitochondria, and impairing a process called peroxisomal β-oxidation. This disruption leads to an increase in lipid accumulation and enhances lipophagy, which is the body's way of breaking down fats. However, when we administered LA, we observed a marked improvement. LA appeared to counteract the damage inflicted by arsenic by boosting SIRT1 levels, improving mitochondrial function, and encouraging peroxisomal β-oxidation.

This study clearly illustrates the potential of alpha-lipoic acid as a protective agent against liver injury due to arsenic exposure. By promoting better lipid metabolism and reducing harmful fat buildup, LA could serve as a valuable option for those affected by liver diseases induced by environmental toxins.

Improves liver health

Most Useful Review

2 people found this helpful

Great price! I would choose alpha-lipoic acid for health. Its effects benefit the nerves, liver, and blood sugar levels. This quality product is offered at a great price—highly recommended!