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SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 1 Capsule
Serving Per Container: 120
Amount Per Serving
%DV
Alpha Lipoic Acid
600 mg
*
Top Medical Research Studies
7
Alpha-lipoic acid reduces migraine attacks
Effects of selected dietary supplements on migraine prophylaxis: A systematic review and dose-response meta-analysis of randomized controlled trials.
High relevance for migraine research
We assessed the effects of alpha-lipoic acid on migraines, focusing on its potential benefits backed by evidence from several trials. These trials provided insights into how alpha-lipoic acid influences migraine characteristics such as attack frequency and severity.
Our analysis indicated that supplementation with alpha-lipoic acid led to a reduction in the number of migraine attacks, with an average decrease of about 1.24 attacks compared to control groups. Although the impact on severity was less pronounced, the decrease in attack frequency is promising for individuals seeking relief from migraines.
It’s important to note that while alpha-lipoic acid showed some positive outcomes, it did not significantly affect all measured aspects of migraines, particularly compared to other dietary supplements. This points to the need for additional research to confirm its benefits and understand its effectiveness in isolation from other treatments.
Our analysis indicated that supplementation with alpha-lipoic acid led to a reduction in the number of migraine attacks, with an average decrease of about 1.24 attacks compared to control groups. Although the impact on severity was less pronounced, the decrease in attack frequency is promising for individuals seeking relief from migraines.
It’s important to note that while alpha-lipoic acid showed some positive outcomes, it did not significantly affect all measured aspects of migraines, particularly compared to other dietary supplements. This points to the need for additional research to confirm its benefits and understand its effectiveness in isolation from other treatments.
Read More
9
Alpha-Lipoic Acid aids migraine prevention
Evaluation of Safety and Efficacy of Add-on Alpha-Lipoic Acid on Migraine Prophylaxis in an Adolescent Population: A Randomized Controlled Trial.
Combination treatment evaluation noted
We conducted a study to understand how alpha-lipoic acid (ALA) could help adolescents suffering from migraines. In this clinical trial, 60 participants were split into two groups: one received flunarizine alone, while the other received flunarizine along with ALA as an add-on treatment. This design allowed us to see if ALA made a significant difference in migraine management.
Remarkably, we observed that the group receiving ALA experienced a significant decrease in the frequency of migraine attacks. In fact, the number of monthly migraine days dropped by an average of 7.7 days. Additionally, 80% of participants in the ALA group reported improvement, while only about one-third of those in the control group felt the same way.
We also noticed improvements in the severity of the migraine attacks, with participants reporting fewer severe headaches. The Pediatric Migraine Disability Assessment scores showed marked improvements as well, indicating better overall functioning in daily life for those taking ALA. Biochemically, levels of serum thiols increased, while markers associated with migraine severity, such as serum CGRP, decreased significantly with ALA treatment. Overall, these findings suggest that ALA could be a promising addition to migraine prevention strategies for adolescents.
Remarkably, we observed that the group receiving ALA experienced a significant decrease in the frequency of migraine attacks. In fact, the number of monthly migraine days dropped by an average of 7.7 days. Additionally, 80% of participants in the ALA group reported improvement, while only about one-third of those in the control group felt the same way.
We also noticed improvements in the severity of the migraine attacks, with participants reporting fewer severe headaches. The Pediatric Migraine Disability Assessment scores showed marked improvements as well, indicating better overall functioning in daily life for those taking ALA. Biochemically, levels of serum thiols increased, while markers associated with migraine severity, such as serum CGRP, decreased significantly with ALA treatment. Overall, these findings suggest that ALA could be a promising addition to migraine prevention strategies for adolescents.
Read More
8
Alpha-lipoic acid's migraine effects unclear
Impact of Fatty Acid Supplementation on Migraine Outcomes: A Systematic Review and Meta-analysis.
Moderate relevance due to insufficient detail
We explored the effects of alpha-lipoic acid on migraines as part of a broader study examining dietary fatty acid supplementation. This research particularly assessed how various supplements, including omega-3 fatty acids and alpha-lipoic acid, influence migraine clinical outcomes.
In the systematic review, we considered six randomized controlled trials that included 407 participants suffering from chronic migraines. The studies aimed to determine if fatty acid supplementation could provide relief from headache intensity, frequency, duration, and overall quality of life.
While the results indicated significant improvements with omega-3 supplementation, the specific contributions of alpha-lipoic acid were not strongly highlighted. This makes it challenging to definitively state the effectiveness of alpha-lipoic acid alone in treating migraines. Overall, the findings suggest that while fatty acids, particularly omega-3, show promise for migraine relief, we need more focused research to fully evaluate alpha-lipoic acid's potential benefits.
In the systematic review, we considered six randomized controlled trials that included 407 participants suffering from chronic migraines. The studies aimed to determine if fatty acid supplementation could provide relief from headache intensity, frequency, duration, and overall quality of life.
While the results indicated significant improvements with omega-3 supplementation, the specific contributions of alpha-lipoic acid were not strongly highlighted. This makes it challenging to definitively state the effectiveness of alpha-lipoic acid alone in treating migraines. Overall, the findings suggest that while fatty acids, particularly omega-3, show promise for migraine relief, we need more focused research to fully evaluate alpha-lipoic acid's potential benefits.
Read More
Most Useful Reviews
8.8
Helps prevent migraines
This product alleviated nerve pain and tingling in my legs. I take it alongside other vitamins to prevent migraines, and firmly believe it has helped stave them off. Do keep it away from pets!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
9
Alpha-Lipoic Acid aids migraine prevention
Evaluation of Safety and Efficacy of Add-on Alpha-Lipoic Acid on Migraine Prophylaxis in an Adolescent Population: A Randomized Controlled Trial.
Combination treatment evaluation noted
We conducted a study to understand how alpha-lipoic acid (ALA) could help adolescents suffering from migraines. In this clinical trial, 60 participants were split into two groups: one received flunarizine alone, while the other received flunarizine along with ALA as an add-on treatment. This design allowed us to see if ALA made a significant difference in migraine management.
Remarkably, we observed that the group receiving ALA experienced a significant decrease in the frequency of migraine attacks. In fact, the number of monthly migraine days dropped by an average of 7.7 days. Additionally, 80% of participants in the ALA group reported improvement, while only about one-third of those in the control group felt the same way.
We also noticed improvements in the severity of the migraine attacks, with participants reporting fewer severe headaches. The Pediatric Migraine Disability Assessment scores showed marked improvements as well, indicating better overall functioning in daily life for those taking ALA. Biochemically, levels of serum thiols increased, while markers associated with migraine severity, such as serum CGRP, decreased significantly with ALA treatment. Overall, these findings suggest that ALA could be a promising addition to migraine prevention strategies for adolescents.
Remarkably, we observed that the group receiving ALA experienced a significant decrease in the frequency of migraine attacks. In fact, the number of monthly migraine days dropped by an average of 7.7 days. Additionally, 80% of participants in the ALA group reported improvement, while only about one-third of those in the control group felt the same way.
We also noticed improvements in the severity of the migraine attacks, with participants reporting fewer severe headaches. The Pediatric Migraine Disability Assessment scores showed marked improvements as well, indicating better overall functioning in daily life for those taking ALA. Biochemically, levels of serum thiols increased, while markers associated with migraine severity, such as serum CGRP, decreased significantly with ALA treatment. Overall, these findings suggest that ALA could be a promising addition to migraine prevention strategies for adolescents.
Read More
8
Alpha-lipoic acid's migraine effects unclear
Impact of Fatty Acid Supplementation on Migraine Outcomes: A Systematic Review and Meta-analysis.
Moderate relevance due to insufficient detail
We explored the effects of alpha-lipoic acid on migraines as part of a broader study examining dietary fatty acid supplementation. This research particularly assessed how various supplements, including omega-3 fatty acids and alpha-lipoic acid, influence migraine clinical outcomes.
In the systematic review, we considered six randomized controlled trials that included 407 participants suffering from chronic migraines. The studies aimed to determine if fatty acid supplementation could provide relief from headache intensity, frequency, duration, and overall quality of life.
While the results indicated significant improvements with omega-3 supplementation, the specific contributions of alpha-lipoic acid were not strongly highlighted. This makes it challenging to definitively state the effectiveness of alpha-lipoic acid alone in treating migraines. Overall, the findings suggest that while fatty acids, particularly omega-3, show promise for migraine relief, we need more focused research to fully evaluate alpha-lipoic acid's potential benefits.
In the systematic review, we considered six randomized controlled trials that included 407 participants suffering from chronic migraines. The studies aimed to determine if fatty acid supplementation could provide relief from headache intensity, frequency, duration, and overall quality of life.
While the results indicated significant improvements with omega-3 supplementation, the specific contributions of alpha-lipoic acid were not strongly highlighted. This makes it challenging to definitively state the effectiveness of alpha-lipoic acid alone in treating migraines. Overall, the findings suggest that while fatty acids, particularly omega-3, show promise for migraine relief, we need more focused research to fully evaluate alpha-lipoic acid's potential benefits.
Read More
7
Alpha-lipoic acid reduces migraine attacks
Effects of selected dietary supplements on migraine prophylaxis: A systematic review and dose-response meta-analysis of randomized controlled trials.
High relevance for migraine research
We assessed the effects of alpha-lipoic acid on migraines, focusing on its potential benefits backed by evidence from several trials. These trials provided insights into how alpha-lipoic acid influences migraine characteristics such as attack frequency and severity.
Our analysis indicated that supplementation with alpha-lipoic acid led to a reduction in the number of migraine attacks, with an average decrease of about 1.24 attacks compared to control groups. Although the impact on severity was less pronounced, the decrease in attack frequency is promising for individuals seeking relief from migraines.
It’s important to note that while alpha-lipoic acid showed some positive outcomes, it did not significantly affect all measured aspects of migraines, particularly compared to other dietary supplements. This points to the need for additional research to confirm its benefits and understand its effectiveness in isolation from other treatments.
Our analysis indicated that supplementation with alpha-lipoic acid led to a reduction in the number of migraine attacks, with an average decrease of about 1.24 attacks compared to control groups. Although the impact on severity was less pronounced, the decrease in attack frequency is promising for individuals seeking relief from migraines.
It’s important to note that while alpha-lipoic acid showed some positive outcomes, it did not significantly affect all measured aspects of migraines, particularly compared to other dietary supplements. This points to the need for additional research to confirm its benefits and understand its effectiveness in isolation from other treatments.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Helps prevent migraines
This product alleviated nerve pain and tingling in my legs. I take it alongside other vitamins to prevent migraines, and firmly believe it has helped stave them off. Do keep it away from pets!
