' 
![]()
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
USERS' SCORE
Good
Based on 107 Reviews
8.5
Supplement Facts
Serving Size: 5 Drops
Amount Per Serving
%DV
Vitamin D (as cholecalciferol)
10 mcg (400 IU)
100%
L.reuteriDSM 17938(L. reuteriProtectis®)
100 million CFU
†
Top Medical Research Studies
8
L. reuteri enhances bowel movements
The effect of Lactobacillus reuteri supplementation in adults with chronic functional constipation: a randomized, double-blind, placebo-controlled trial.
Study shows significant improvement
We conducted a double-blind, placebo-controlled trial involving 40 adults with functional constipation to see if Lactobacillus reuteri could improve their condition. Over four weeks, those receiving L. reuteri had a notable increase in weekly bowel movements, averaging 2.6 more compared to just 1.0 in the placebo group.
While this probiotic showed promise in enhancing bowel movement frequency, it did not significantly change stool consistency. This suggests that L. reuteri may be a beneficial option for adults struggling with constipation.
While this probiotic showed promise in enhancing bowel movement frequency, it did not significantly change stool consistency. This suggests that L. reuteri may be a beneficial option for adults struggling with constipation.
Read More
4
Probiotics may aid constipation relief
"The role of L. reuteri DSM17938 in nutritional recovery and treatment of constipation in children and adolescents with anorexia nervosa - a randomized, double blind, placebo controlled study".
Relevant for pediatric treatment methods
We investigated the effectiveness of the probiotic Lactobacillus reuteri DSM 17938 for treating constipation in young patients suffering from anorexia nervosa.
In a randomized, double-blind study with 31 pediatric female patients, we compared those taking the probiotic to a placebo over three months alongside nutritional therapy.
While we did not see a significant difference in constipation relief between the two groups immediately, there may be potential benefits in stool frequency and nutritional recovery after six months.
In a randomized, double-blind study with 31 pediatric female patients, we compared those taking the probiotic to a placebo over three months alongside nutritional therapy.
While we did not see a significant difference in constipation relief between the two groups immediately, there may be potential benefits in stool frequency and nutritional recovery after six months.
Read More
2
Lactobacillus reuteri ineffective for constipation
Lack of Benefit of Lactobacillus reuteri DSM 17938 as an Addition to the Treatment of Functional Constipation.
Relevance score not specified.
This study set out to examine whether Lactobacillus reuteri DSM 17938 could help children suffering from functional constipation. Conducted as a controlled trial, it compared children who received this probiotic alongside lactulose to those who received a placebo with lactulose.
Unfortunately, results showed no notable differences in stool frequency, consistency, or discomfort between the two groups. Therefore, it concluded that Lactobacillus reuteri DSM 17938 doesn't provide additional benefits in managing constipation in children. However, the small sample size suggests we should take these findings with caution.
Unfortunately, results showed no notable differences in stool frequency, consistency, or discomfort between the two groups. Therefore, it concluded that Lactobacillus reuteri DSM 17938 doesn't provide additional benefits in managing constipation in children. However, the small sample size suggests we should take these findings with caution.
Read More
Most Useful Reviews
9.5
Effective against constipation
The most remarkable product I received! It genuinely alleviates my baby’s gas and constipation. A few drops work wonders, providing relief quickly. Previously, we struggled with colic and sleepless nights despite trying various methods. I wholeheartedly recommend this drop for anyone in a similar situation.
Read More
9.5
Improved digestion
I bought this for my nephew who had constipation since birth due to being delivered by caesarean section. The quality is excellent, and it contains beneficial bacteria. After using it, his constipation disappeared, and it significantly improved his digestion. Plus, it's easier to use than pharmacy products.
Read More
9.5
Constipation relief
I used this for my one-year-old son, who often suffers from constipation. Initially unsure of the timing, I gave it in the morning. After a few days, his constipation improved dramatically, resulting in normal stools. This product appears beneficial for overall digestive health, and I plan to continue using it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
9
Lactobacillus reuteri enhances H. pylori treatment
Probiotic containing Lactobacillus reuteri DSM 17648 as an adjunct treatment for Helicobacter pylori infection: A randomized, double-blind, placebo-controlled trial.
Highly relevant study results
We explored the effectiveness of Lactobacillus reuteri DSM 17648 as an adjunct treatment for patients with Helicobacter pylori infection. In a rigorous randomized, double-blind, placebo-controlled trial involving 90 treatment-naïve patients, we found that adding this probiotic significantly boosted the H. pylori eradication rate.
Additionally, participants taking Lactobacillus reuteri reported notable relief from gastrointestinal symptoms like constipation and abdominal pain, along with fewer treatment-related side effects. This suggests that Lactobacillus reuteri could be a valuable tool in enhancing conventional H. pylori treatments.
Additionally, participants taking Lactobacillus reuteri reported notable relief from gastrointestinal symptoms like constipation and abdominal pain, along with fewer treatment-related side effects. This suggests that Lactobacillus reuteri could be a valuable tool in enhancing conventional H. pylori treatments.
Read More
9
Lactobacillus reuteri improves gut motility
Microvesicles from Lactobacillus reuteri (DSM-17938) completely reproduce modulation of gut motility by bacteria in mice.
High relevance to gut health
We explored how microvesicles from Lactobacillus reuteri impact gut motility, specifically in relation to constipation. Our study involved comparing the effects of the bacterium itself, its microvesicles, and the surrounding culture medium on mouse jejunum and colon segments.
We found that both the bacteria and their microvesicles effectively decreased contractions in the jejunum while boosting them in the colon. Notably, the removal of microvesicles significantly reduced their effects on motility, highlighting their critical role. These findings suggest exciting possibilities for bacterial treatments for constipation.
We found that both the bacteria and their microvesicles effectively decreased contractions in the jejunum while boosting them in the colon. Notably, the removal of microvesicles significantly reduced their effects on motility, highlighting their critical role. These findings suggest exciting possibilities for bacterial treatments for constipation.
Read More
8
Walnut fiber and probiotics relieve constipation
Water-insoluble dietary fiber from walnut relieves constipation through Limosilactobacillus reuteri-mediated serotonergic synapse and neuroactive ligand-receptor pathways.
High relevance for constipation management
We examined how water-insoluble dietary fiber from walnuts, along with Limosilactobacillus reuteri, can help relieve constipation. Our analysis found that this fiber effectively lessened constipation symptoms in mice by enhancing gut motility and changing gut bacteria composition.
L. reuteri showed impressive results, working through specific neurochemical pathways that influence bowel movements. The findings suggest that incorporating walnut fiber and L. reuteri into diets could be a promising natural strategy for managing constipation.
L. reuteri showed impressive results, working through specific neurochemical pathways that influence bowel movements. The findings suggest that incorporating walnut fiber and L. reuteri into diets could be a promising natural strategy for managing constipation.
Read More
8
L. reuteri improves infant constipation
Effect of Lactobacillus reuteri NCIMB 30351 drops on symptoms of infantile functional gastrointestinal disorders and gut microbiota in early infants: Results from a randomized, placebo-controlled clinical trial.
Relevant and safe treatment evaluated
We explored the effects of Lactobacillus reuteri NCIMB 30351 on infants experiencing functional gastrointestinal disorders, including constipation. In a randomized, placebo-controlled trial, 90 infants aged 1 to 4 months received either the probiotic or a placebo for 25 days.
The results indicated a noteworthy increase in evacuation frequency for infants with constipation. We also saw significant reductions in colic symptoms, including crying duration. With no reported side effects, L. reuteri seems to be a promising option for easing constipation in young children.
The results indicated a noteworthy increase in evacuation frequency for infants with constipation. We also saw significant reductions in colic symptoms, including crying duration. With no reported side effects, L. reuteri seems to be a promising option for easing constipation in young children.
Read More
8
Infant formula reduces constipation effectively
An Observational Real-Life Study with a New Infant Formula in Infants with Functional Gastro-Intestinal Disorders.
High relevance for infant health
We examined the effects of a new infant formula on functional gastrointestinal disorders, including constipation, in 196 infants. Over two weeks, this formula, enriched with various nutrients and a specific probiotic, was found to significantly reduce gastrointestinal issues.
Notably, constipation rates dropped from 18.8% to just 6.5% within three days. Additionally, we recorded overall improvements in the infants' quality of life by the end of the study. This research highlights the beneficial role nutrition can play in managing infant FGIDs.
Notably, constipation rates dropped from 18.8% to just 6.5% within three days. Additionally, we recorded overall improvements in the infants' quality of life by the end of the study. This research highlights the beneficial role nutrition can play in managing infant FGIDs.
Read More
User Reviews
USERS' SCORE
Good
Based on 107 Reviews
8.5
10
No constipation experienced
I've used it since my baby was one week old, giving three drops every night. Now at three months, he has never experienced constipation, no gas buildup, and rarely cries in the evening.
10
Persistent constipation issue
I’ve had constipation since I was a newborn. I started using this when I was four, and I now go every morning. I've been using it for over a year, but it hasn't completely resolved my issue. I still take 5 drops of it after my bath, and although I used to cry at night, I'm hopeful for an improvement.
Read More
10
Regular bowel movements
I gave my one-year-old this product after struggling with constipation from 6 months old. After trying various options, only these probiotics established a regular bowel routine. After my vacation, the problems returned, so I ordered it again from iHerb instead of the pharmacy, based on good reviews.
Read More
10
Effective daily bowel movements
This was given to my baby at one month old, and since then, we haven’t dealt with constipation! She sleeps well without any colic or crying.
10
Effective for indigestion
Wonderful in all respects for treating constipation, bloating, gas and indigestion in newborns. Excellent product.
