Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.3
USERS' SCORE
Good
Based on 7 Reviews
8.2
Supplement Facts
Serving Size:  1 Capsule
Amount Per Serving
%DV
Thiamin (as thiamine hydrochloride)
25 mg
2,083%
Riboflavin (as riboflavin 5'-phosphate sodium)
20 mg
1,538%
Niacin (as inositol hexanicotinate and nicotinic acid)
95 mg NE
594%
Vitamin B6 (as pyridoxal 5'-phosphate)
20 mg
1,176%
Folate [as Quatrefolic® (6S)-5-methyltetrahydrofolate, glucosamine salt and calcium folinate]
680 mcg DFE (400 mcg)
170%
Vitamin B12 (as MECOBALACTIVE® methylcobalamin and adenosylcobalamin)
50 mcg
2,083%
Biotin
750 mcg
2,500%
Pantothenic Acid (as d-calcium pantothenate)
125 mg
2,500%
Choline (as choline bitartrate)
50 mg
9%

Top Medical Research Studies

8
Niacin helps alleviate anxiety symptoms
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.

Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Read More
We explored how vitamin B could help fight anxiety and depression linked to nicotine withdrawal in young male rats.

The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.

The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
Read More
7
Vitamin B may alleviate anxiety symptoms
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.

The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
Read More

Most Useful Reviews

8.8
Postpartum anxiety control
I never skip a day! A friend suggested this for my B deficiency symptoms, including postpartum anxiety. Within four days, I felt much better and noticed the difference if I didn't take it. My anxiety is more controlled, I'm clearer in thought, and I have plenty of energy. I look forward to seeing if this continued usage will benefit other symptoms.
Read More
9.5
Effective B vitamins
This product was recommended for postpartum anxiety. Since starting, I've noticed a marked improvement and can certainly tell when I've missed my daily dose. These B vitamins seem highly effective; the potency and availability are excellent. I will definitely reorder.
Read More
9.5
Helps with anxiety
Five Stars. Really helps with my anxiety.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.3
  • All Researches
8
Niacin helps alleviate anxiety symptoms
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.

Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Read More
We explored how vitamin B could help fight anxiety and depression linked to nicotine withdrawal in young male rats.

The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.

The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
Read More
7
Vitamin B may alleviate anxiety symptoms
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.

The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
Read More
7
Vitamin B aids anxiety recovery
We explored the effects of vitamin B supplementation on anxiety and cognitive function in male Swiss albino mice following traumatic brain injury (TBI). Our research found that vitamin B appears to improve neurological impairments, enhance memory, and reduce anxiety-like behaviors.

Additionally, we saw a reduction in oxidative stress markers, indicating better neuronal health. This suggests that vitamin B not only helps with anxiety but also plays a role in recovery from cognitive dysfunctions associated with TBI.
Read More
7
No significant anxiety improvement
We explored the effectiveness of vitamin B complex in treating anxiety among patients with Post-COVID-19 syndrome (PC19S) through the PreVitaCOV trial. This study involved 240 participants who were given either prednisolone, vitamin B1, B6, and B12, a combination of these treatments, or a placebo. While the trial showed high feasibility and safety, it ultimately did not demonstrate significant benefits in symptom change over placebo in anxiety or other evaluated symptoms.
Read More

User Reviews

USERS' SCORE
Good
Based on 7 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8.8
Postpartum anxiety control
I never skip a day! A friend suggested this for my B deficiency symptoms, including postpartum anxiety. Within four days, I felt much better and noticed the difference if I didn't take it. My anxiety is more controlled, I'm clearer in thought, and I have plenty of energy. I look forward to seeing if this continued usage will benefit other symptoms.
Read More
9.5
Effective B vitamins
This product was recommended for postpartum anxiety. Since starting, I've noticed a marked improvement and can certainly tell when I've missed my daily dose. These B vitamins seem highly effective; the potency and availability are excellent. I will definitely reorder.
Read More
9.5
Helps with anxiety
Five Stars. Really helps with my anxiety.
Read More
9.5
Reduces anxiety
I love this B Complex, especially as it doesn’t contain excessive amounts of B12 which can cause me anxiety. The B6 form is also the active P5P. I highly recommend this B Complex.
Read More
8.8
Supports anxiety management
Seeking Health B Complex contains essential B vitamins for maintaining nervous system health and energy. It has positively impacted my mood, energy, skin, hair, and nails, and crucially, it has helped me manage stress and anxiety effectively. A solid choice for supporting overall health.
Read More

Frequently Asked Questions

Anxiety is a natural and often healthy emotion characterized by feelings of worry, nervousness, or fear about an impending event or situation. While some level of anxiety is a normal reaction to stress, excessive or chronic anxiety can become a mental health issue. It may present in various forms, from everyday worries to more severe conditions such as generalized anxiety disorder (GAD), panic disorder, or social anxiety disorder. Symptoms can manifest both psychologically, such as persistent worry and difficulty concentrating, and physically, including symptoms like increased heart rate, sweating, or fatigue.

Understanding the difference between normal anxiety and an anxiety disorder is crucial. Normal anxiety can be beneficial, motivating you to prepare for important events like exams or public speaking. However, when it starts to interfere with daily activities or leads to avoidance behaviors, it may indicate the need for professional help. Treatments for anxiety often include therapy, medications, and lifestyle changes, allowing individuals to manage their symptoms effectively. If someone is struggling with anxiety that impacts their quality of life, seeking guidance from a healthcare professional is a key step toward recovery.

Vitamin B Complex refers to a group of water-soluble vitamins that play important roles in cell metabolism and overall health. This group typically includes eight essential vitamins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin). Each of these vitamins contributes uniquely to various bodily functions, such as energy production, red blood cell formation, and nervous system function. For instance, B12 and folate are crucial in preventing anemia, while B6 is vital for brain development and function.

Many people can obtain their daily requirements of B vitamins through a balanced diet that includes whole grains, meats, eggs, nuts, leafy greens, and dairy products. However, certain groups—like vegetarians, pregnant women, and older adults—may benefit from supplementation to meet their nutritional needs. It's important to consult with a healthcare professional before starting any supplement regimen, as excessive intake of certain B vitamins can lead to adverse effects. Overall, ensuring adequate intake of Vitamin B Complex is vital for maintaining energy levels and supporting overall health.

Vitamin B complex is often touted for its potential benefits in improving mood and reducing symptoms of anxiety. B vitamins, particularly B6, B12, and folate, play crucial roles in the synthesis of neurotransmitters such as serotonin and dopamine, which are vital for regulating mood and emotional well-being. Some studies suggest that individuals with anxiety may have lower levels of certain B vitamins, and supplementation could help in addressing these deficiencies. However, it is essential to note that while B vitamins can support overall brain health, they should not be considered a standalone treatment for anxiety disorders.

For those considering vitamin B complex supplements, it's advisable to consult with a healthcare professional to determine the most effective approach for individual needs. While a balanced diet rich in whole grains, meats, eggs, dairy, and leafy greens typically provides sufficient B vitamins, supplementation may be beneficial for some, particularly in cases of deficiency. In summary, while vitamin B complex may help alleviate some anxiety symptoms, it is most effective as part of a comprehensive treatment plan that includes therapy, lifestyle changes, and, if necessary, medication.

Based on user reviews, the timeline for seeing results from this B Complex supplement can vary. Many users have reported positive effects on mood and stress management shortly after starting the supplement. For instance, one user mentioned that it has helped them manage stress and anxiety effectively, indicating quick improvements in their well-being ((Read Review)). However, experiences can differ significantly; some users found the product to be too strong and even reported an increase in anxiety symptoms, which suggests it may not work for everyone in the same timeframe ((Read Review); (Read Review)).

Additionally, the effectiveness could depend on individual tolerance to the dosage in the supplement. A user expressed satisfaction with its formulation while another mentioned that high doses led to anxiety. Thus, while some individuals may notice beneficial effects relatively quickly, others might experience adverse reactions that delay obtaining any positive results. It's essential to monitor your own response to the supplement and consult with a healthcare professional if needed.

Based on the available studies, the scientific support for Vitamin B as a supplement for anxiety appears promising, primarily in animal models. Research indicates that Vitamin B can help alleviate anxiety symptoms by restoring neurotransmitter levels and improving behavior in stressed rats [1]. Additionally, Vitamin B has shown potential in reducing anxiety-like symptoms following traumatic brain injury [3] and even in nicotine withdrawal scenarios [5].

However, it is important to note that while these studies highlight the benefits of Vitamin B in animal populations, human trials have shown mixed results. In one study investigating its effectiveness in Post-COVID-19 anxiety, while the trial was feasible and safe, it did not demonstrate significant benefits over placebo [4]. Therefore, while there is a foundation of animal research suggesting Vitamin B may have helpful effects on anxiety, more robust human studies are needed to draw definitive conclusions.

Based on user reviews, many individuals have reported favorable improvements in various aspects of their health after taking this B Complex supplement. Specifically, users have noted enhancements in mood, energy levels, and overall well-being. One user stated that it positively impacted their mood, energy, skin, hair, and nails, while also aiding in effective stress and anxiety management ((Read Review)). Another user praised the product for its balanced formulation, particularly highlighting its lower B12 content, which they found to mitigate anxiety symptoms ((Read Review)).

However, it's important to note that individual experiences may vary significantly. Some users have reported adverse effects, such as increased heart rate and anxiety, even at lower doses, indicating that the product may not be suitable for everyone ((Read Review); (Read Review)). Overall, while many find the supplement beneficial, personal tolerance and response to the dosage play a crucial role in determining effectiveness.

Users reported mixed experiences when combining this B Complex supplement with others for managing anxiety. One enthusiastic reviewer highlighted the product's ability to support not only energy and overall health but also its effectiveness in managing stress and anxiety without causing excessive side effects due to its balanced B12 content ((Read Review); (Read Review)). This suggests that when paired with other supportive supplements, users can achieve beneficial outcomes.

In contrast, several users experienced adverse reactions, such as increased anxiety and a rapid heartbeat, leading them to question the high dosages of certain vitamins in the B Complex. These individuals noted that even reducing the dosage did not alleviate their anxiety symptoms, which points to the importance of personal tolerance when considering combining this with other supplements ((Read Review); (Read Review)). Therefore, while some users found success integrating this supplement for anxiety management, others faced challenges that might warrant caution and a tailored approach.

Based on user reviews, the right dose for Vitamin B Complex when treating anxiety appears to vary significantly among individuals. Some users, like the reviewer of Seeking Health B Complex, report that the combination of essential B vitamins helped manage their stress and anxiety effectively, leading to improvements in mood and overall health (Read Review). In contrast, others have experienced negative side effects, such as rapid heartbeat and increased anxiety, due to what they perceived as excessive dosages (Read Review).

For those with heightened sensitivity to specific B vitamins, particularly B12, it may be beneficial to select products that contain lower amounts of this vitamin, as one reviewer noted that excessive B12 can exacerbate anxiety symptoms (Read Review). Additionally, reviewers have mentioned that reducing the dosage did not always alleviate anxiety symptoms, pointing to the need for caution when initiating B Complex supplementation (Read Review). Ultimately, users suggest a tailored approach based on individual responses and sensitivities.

8.8
Supports anxiety management
Seeking Health B Complex contains essential B vitamins for maintaining nervous system health and energy. It has positively impacted my mood, energy, skin, hair, and nails, and crucially, it has helped me manage stress and anxiety effectively. A solid choice for supporting overall health.
1.3
Causes anxiety
Not for me. It causes a rapid heartbeat and anxiety. The dosage of the B vitamins is very high. I’m sure this is a good brand; perhaps I should try the MF version instead.
1.3
Induces anxiety
Too strong for me. The dosage seems excessive and it gave me anxiety even when I reduced it to half.
9.5
Reduces anxiety
I love this B Complex, especially as it doesn’t contain excessive amounts of B12 which can cause me anxiety. The B6 form is also the active P5P. I highly recommend this B Complex.
7
Vitamin B may alleviate anxiety symptoms
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.

The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
7
Vitamin B aids anxiety recovery
We explored the effects of vitamin B supplementation on anxiety and cognitive function in male Swiss albino mice following traumatic brain injury (TBI). Our research found that vitamin B appears to improve neurological impairments, enhance memory, and reduce anxiety-like behaviors.

Additionally, we saw a reduction in oxidative stress markers, indicating better neuronal health. This suggests that vitamin B not only helps with anxiety but also plays a role in recovery from cognitive dysfunctions associated with TBI.
We explored how vitamin B could help fight anxiety and depression linked to nicotine withdrawal in young male rats.

The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.

The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
7
No significant anxiety improvement
We explored the effectiveness of vitamin B complex in treating anxiety among patients with Post-COVID-19 syndrome (PC19S) through the PreVitaCOV trial. This study involved 240 participants who were given either prednisolone, vitamin B1, B6, and B12, a combination of these treatments, or a placebo. While the trial showed high feasibility and safety, it ultimately did not demonstrate significant benefits in symptom change over placebo in anxiety or other evaluated symptoms.

References

  1. Chen J, Liu J, Zhang P, Zhang S. [Effects of Vitamin B on Behaviors, Brain Monoamine Neurotransmitters, and Brain-Derived Neurotrophic Factor in Depressive Rats]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2025;56:206. doi:10.12182/20250160608
  2. Samad N, Hameed A, Manzoor N, Shoukat S, Irfan A, et al. Antioxidant and neuro-modulatory effects of niacin prevent D-galactose-induced behavioral deficits and memory impairment. Exp Gerontol. 2024;198:112624. doi:10.1016/j.exger.2024.112624
  3. Yadav P, Nasir F, Sivanandam TM. Neuroprotective effect of vitamin B supplementation on cognitive functions and neuronal morphology at different time intervals after traumatic brain injury in male Swiss albino mice. Neurochem Int. 2024;180:105869. doi:10.1016/j.neuint.2024.105869
  4. Tengelmann C, Joos S, Kaußner Y, Malzahn U, Lunden L, et al. Feasibility, safety and effectiveness of prednisolone and vitamin B1, B6, and B12 in patients with post-COVID-19-syndrome (PreVitaCOV) - protocol of a randomised, double-blind, placebo-controlled multicentre trial in primary care (phase IIIb). BMC Infect Dis. 2024;24:56. doi:10.1186/s12879-023-08925-2
  5. Pahlavani H, Masoudi M, Khoshroo N, Kakhki S, Mahdi Rezavanimehr M, et al. Vitamin B reversed anxiety and depression induced by adolescent nicotine withdrawal through alteration the inflammatory, oxidative and serotoninergic profiles in male rats. Biochem Pharmacol. 2023;217:115832. doi:10.1016/j.bcp.2023.115832
  6. Kakhki S, Goodarzi M, Abbaszade-Cheragheali A, Rajabi M, Masoumipour AH, et al. Folic acid supplementation improved cognitive deficits associated with lithium administration during pregnancy in rat offspring. Int J Dev Neurosci. 2023;83:615. doi:10.1002/jdn.10289
  7. Shemirani F, Titcomb TJ, Saxby SM, Eyck PT, Rubenstein LM, et al. Association of serum homocysteine, folate, and vitamin B and mood following the Swank and Wahls elimination dietary interventions in relapsing-remitting multiple sclerosis: Secondary analysis of the WAVES trial. Mult Scler Relat Disord. 2023;75:104743. doi:10.1016/j.msard.2023.104743
image