Microencapsulated LM-20 effective in colitisMicroencapsulation and Probiotic Characterization of LM-20: Therapeutic Application in a Murine Model of Ulcerative Colitis.
We investigated the effects of microencapsulated LM-20, a probiotic, on ulcerative colitis in a lab model. Using advanced microencapsulation techniques, we ensured strong survival rates of this probiotic in harsh gastrointestinal conditions.
Our results were promising—mice receiving LM-20 showed an impressive 83.3% reduction in disease activity. They also had lower levels of harmful inflammatory markers, mirroring those of healthy mice.
This suggests that LM-20 could be a beneficial therapy for managing ulcerative colitis.
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Lactobacillus aids ulcerative colitis L. Modulates the Intestinal Microecology to Treat DSS-Induced Ulcerative Colitis: UHPLC-OE-MS/MS, Network Pharmacology, and Experimental Validation.
We explored how Lactobacillus might play a role in treating ulcerative colitis (UC) through various scientific methods. In our investigation, we found that Lactobacillus significantly reduced harmful inflammation markers and improved gut health in mice with UC.
Additionally, it helped increase beneficial gut bacteria and restored balance in the intestines. These findings suggest that Lactobacillus could be a promising natural treatment for managing this condition by supporting a healthier intestinal environment.
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Lactobacillus shows promise for colitisEffect of DSW3805 Isolated from Kimchi for Gut Health Attenuating Colonic Inflammation in a Dextran Sulfate Sodium-Induced Mouse Model.
We investigated the effects of DSW3805, a probiotic isolated from Korean kimchi, on colitis in mice induced by dextran sulfate sodium.
Mice treated with DSW3805 showed improvements in gut health, as evidenced by less colonic damage and decreased inflammation markers.
We noted that the probiotics also increased beneficial bacteria ratios in the gut and produced beneficial short-chain fatty acids.
Overall, DSW3805 may serve as a functional food to enhance gut health and alleviate colitis symptoms.
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Probiotic enhancement for colitis treatmentMetal ion coordinated tea polyphenol nanocoating for enhanced probiotic therapy in inflammatory bowel disease.
In our research, we explored the effectiveness of probiotic treatments for inflammatory bowel disease (IBD) using metal-phenolic networks. We focused on tea polyphenols, like gallic acid and epigallocatechin, mixed with Lactobacillus rhamnosus.
The findings showed that these new formulations significantly improved the survival rates of probiotics in the gastrointestinal tract and effectively reduced signs of ulcerative colitis. Notably, one formulation promoted beneficial bacteria growth while suppressing harmful ones. This suggests that these advanced probiotic coatings could be a game-changer in IBD therapies.
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Lactobacillus with selenium combats colitisTriple-Functional Probiotics with Intracellularly Synthesized Selenium Nanoparticles for Colitis Therapy by Regulating the Macrophage Phenotype and Modulating Gut Microbiota.
We explored a new probiotic treatment for colitis using a unique blend of Lactobacillus and selenium nanoparticles. This innovative approach, designed to overcome underlying issues in colitis, targets the inflammation and dysbiosis seen in patients.
The results from our study indicated that these probiotics effectively reduced oxidative stress and improved gut health by regulating macrophage activity. This dual-action helps calm inflammation and restore balance in gut bacteria.
Overall, we saw promising effects in mice with induced colitis, but further research is needed to fully understand their benefits in humans.
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