Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.5
USERS' SCORE
Good
Based on 2 Reviews
8.7
Supplement Facts
Serving Size: One (1) Tablet
Amount Per Serving
%DV
Calories
0
 
Total Carbohydrate
<1 g
<1%+
Total Sugars
0 g
**
Incl. 0 g Added Sugars
 
0%+
Xylitol
<1 g
**
Lactobacillus rhamnosus GG
53 mg (10 billion CFUs)
**

Top Medical Research Studies

We investigated the effects of microencapsulated LM-20, a probiotic, on ulcerative colitis in a lab model. Using advanced microencapsulation techniques, we ensured strong survival rates of this probiotic in harsh gastrointestinal conditions.

Our results were promising—mice receiving LM-20 showed an impressive 83.3% reduction in disease activity. They also had lower levels of harmful inflammatory markers, mirroring those of healthy mice.

This suggests that LM-20 could be a beneficial therapy for managing ulcerative colitis.
Read More
9
Lactobacillus shows promise for colitis
We investigated the effects of DSW3805, a probiotic isolated from Korean kimchi, on colitis in mice induced by dextran sulfate sodium.

Mice treated with DSW3805 showed improvements in gut health, as evidenced by less colonic damage and decreased inflammation markers.

We noted that the probiotics also increased beneficial bacteria ratios in the gut and produced beneficial short-chain fatty acids.

Overall, DSW3805 may serve as a functional food to enhance gut health and alleviate colitis symptoms.
Read More
8
Marine probiotic shows gut benefits
We explored the effects of a new probiotic, HY0110, derived from marine sources, known for its potential in gut health. In our research, HY0110 showed impressive antibacterial properties and antioxidant capacity.

In models of colitis, it helped reduce inflammation and restore a healthy gut microbiome. By enhancing important metabolic compounds, HY0110 supports immune function and inflammation regulation.

Overall, our findings indicate that HY0110 could be a promising functional food for managing inflammatory bowel disease.
Read More

Most Useful Reviews

9.5
Life-saving probiotic
A few years ago, I was diagnosed with Colitis, and the prescribed medication made matters worse. So, I sought alternatives and began using Culturelle. Within a week, I felt significantly better and returned to near normality. It's a revelation! I now prefer trying alternative treatments before consulting a doctor.
Read More
9.5
Fast relief
This stuff is amazing! After suffering from horrible digestive issues for over three weeks, to the point of being diagnosed with collagenous colitis, I started taking this on Friday. By Monday, my condition had improved immensely—I'm now 98% better!
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.5
  • All Researches
We investigated the effects of microencapsulated LM-20, a probiotic, on ulcerative colitis in a lab model. Using advanced microencapsulation techniques, we ensured strong survival rates of this probiotic in harsh gastrointestinal conditions.

Our results were promising—mice receiving LM-20 showed an impressive 83.3% reduction in disease activity. They also had lower levels of harmful inflammatory markers, mirroring those of healthy mice.

This suggests that LM-20 could be a beneficial therapy for managing ulcerative colitis.
Read More
9
Lactobacillus aids ulcerative colitis
We explored how Lactobacillus might play a role in treating ulcerative colitis (UC) through various scientific methods. In our investigation, we found that Lactobacillus significantly reduced harmful inflammation markers and improved gut health in mice with UC.

Additionally, it helped increase beneficial gut bacteria and restored balance in the intestines. These findings suggest that Lactobacillus could be a promising natural treatment for managing this condition by supporting a healthier intestinal environment.
Read More
9
Lactobacillus shows promise for colitis
We investigated the effects of DSW3805, a probiotic isolated from Korean kimchi, on colitis in mice induced by dextran sulfate sodium.

Mice treated with DSW3805 showed improvements in gut health, as evidenced by less colonic damage and decreased inflammation markers.

We noted that the probiotics also increased beneficial bacteria ratios in the gut and produced beneficial short-chain fatty acids.

Overall, DSW3805 may serve as a functional food to enhance gut health and alleviate colitis symptoms.
Read More
9
Probiotic enhancement for colitis treatment
In our research, we explored the effectiveness of probiotic treatments for inflammatory bowel disease (IBD) using metal-phenolic networks. We focused on tea polyphenols, like gallic acid and epigallocatechin, mixed with Lactobacillus rhamnosus.

The findings showed that these new formulations significantly improved the survival rates of probiotics in the gastrointestinal tract and effectively reduced signs of ulcerative colitis. Notably, one formulation promoted beneficial bacteria growth while suppressing harmful ones. This suggests that these advanced probiotic coatings could be a game-changer in IBD therapies.
Read More
9
Lactobacillus with selenium combats colitis
We explored a new probiotic treatment for colitis using a unique blend of Lactobacillus and selenium nanoparticles. This innovative approach, designed to overcome underlying issues in colitis, targets the inflammation and dysbiosis seen in patients.

The results from our study indicated that these probiotics effectively reduced oxidative stress and improved gut health by regulating macrophage activity. This dual-action helps calm inflammation and restore balance in gut bacteria.

Overall, we saw promising effects in mice with induced colitis, but further research is needed to fully understand their benefits in humans.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Life-saving probiotic
A few years ago, I was diagnosed with Colitis, and the prescribed medication made matters worse. So, I sought alternatives and began using Culturelle. Within a week, I felt significantly better and returned to near normality. It's a revelation! I now prefer trying alternative treatments before consulting a doctor.
Read More
9.5
Fast relief
This stuff is amazing! After suffering from horrible digestive issues for over three weeks, to the point of being diagnosed with collagenous colitis, I started taking this on Friday. By Monday, my condition had improved immensely—I'm now 98% better!
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Cui C, Tang J, Chen J, Zhang B, Li R, et al. Lactobacillus acidophilus extracellular vesicles-coated UiO-66-NH@siRNA nanoparticles for ulcerative colitis targeted gene therapy and gut microbiota modulation. J Nanobiotechnology. 2025;23:301. doi:10.1186/s12951-025-03376-0
  2. Huang F, Yang N, Zhang Q, Luo C, Wang J, et al. Marine-Derived HY0110 as a Next-Generation Functional Food Probiotic: Comprehensive In Vitro and In Vivo Bioactivity Evaluation and Synergistic Fermentation of Extract Powder. Foods. 2025;14. doi:10.3390/foods14071181
  3. Zhang L, Liu X, Xu M, Cheng X, Li N, et al. L. Modulates the Intestinal Microecology to Treat DSS-Induced Ulcerative Colitis: UHPLC-OE-MS/MS, Network Pharmacology, and Experimental Validation. Foods. 2025;14. doi:10.3390/foods14071145
  4. Lee NK, Lee Y, Shin DS, Choi YM, Lee J, et al. Effect of DSW3805 Isolated from Kimchi for Gut Health Attenuating Colonic Inflammation in a Dextran Sulfate Sodium-Induced Mouse Model. Nutrients. 2025;17. doi:10.3390/nu17071259
  5. Gao L, Liu Y, Ye L, Liang S, Lin J, et al. Metal ion coordinated tea polyphenol nanocoating for enhanced probiotic therapy in inflammatory bowel disease. Biomaterials. 2025;321:123323. doi:10.1016/j.biomaterials.2025.123323
  6. Li P, Zhu L, Song C, Wu M, Zhu X, et al. Triple-Functional Probiotics with Intracellularly Synthesized Selenium Nanoparticles for Colitis Therapy by Regulating the Macrophage Phenotype and Modulating Gut Microbiota. ACS Nano. 2025;19:14213. doi:10.1021/acsnano.5c00574
  7. Fang Z, Yang X, Shang L. Microfluidic-derived montmorillonite composite microparticles for oral codelivery of probiotic biofilm and postbiotics. Sci Adv. 2025;11:eadt2131. doi:10.1126/sciadv.adt2131
  8. Zhou M, Yang Y, Wang Z, Gao Y, Dang D, et al. Effect of Recombinant Tuxtide Intervention on DSS-induced Acute UC Mouse Model. Curr Top Med Chem. 2025. doi:10.2174/0115680266343609250226094349
  9. Garfias Noguez C, Ramírez Damián M, Ortiz Moreno A, Márquez Flores YK, Alamilla Beltrán L, et al. Microencapsulation and Probiotic Characterization of LM-20: Therapeutic Application in a Murine Model of Ulcerative Colitis. Nutrients. 2025;17. doi:10.3390/nu17050749
  10. Wang Y, Li T, Dong Z, Zhang Q, Mi J, et al. Extracellular Vesicles From Lactobacillus fermentum Enhance Intestinal Barrier Integrity and Restore Gut Microbial Homeostasis in Experimental Murine Colitis. J Nutr. 2025. doi:10.1016/j.tjnut.2025.03.001
  11. Gong GZ, Li RT, Cui SS, Zhu YT, Duan ZZ, et al. Synbiotic yacon juice fermented by Lactiplantibacillus plantarum QS7T attenuates dextran sodium sulfate-induced ulcerative colitis in mice. J Food Sci. 2025;90:e17478. doi:10.1111/1750-3841.17478
  12. Zuo X, Zhang T, Dong X, Liu J, Liu Y. Identification of the key tryptophan metabolic characteristics of Lactiplantibacillus plantarum for aryl hydrocarbon receptor activation and ulcerative colitis alleviation. Food Res Int. 2025;203:115766. doi:10.1016/j.foodres.2025.115766
  13. Kang YY, Song HJ, Park SY, Oh DN, Kim GY, et al. Comparative Effects of Probiotics and Paraprobiotics Derived from , , and in a DSS-Induced Ulcerative Colitis Mouse Model. J Microbiol Biotechnol. 2025;35:e2411045. doi:10.4014/jmb.2411.11045
  14. Wang Z, Liu T, Liu L, Xie J, Tang F, et al. Lactobacillus vaginalis alleviates DSS induced colitis by regulating the gut microbiota and increasing the production of 3-indoleacrylic acid. Pharmacol Res. 2025;213:107663. doi:10.1016/j.phrs.2025.107663
  15. Pan H, Yang S, Kulyar MF, Ma H, Li K, et al. 016 Alleviates Mice Colitis by Modulating Oxidative Stress, Gut Microbiota, and Microbial Metabolism. Nutrients. 2025;17. doi:10.3390/nu17030452
  16. Shao J, Xia Y, Wang G, Xiong Z, Yang Y, et al. The bsh1 gene of Lactobacillus plantarum AR113 ameliorates liver injury in colitis mice. NPJ Sci Food. 2025;9:22. doi:10.1038/s41538-025-00373-3
image