Lactobacillus
8
Lactobacillus aids ulcerative colitis treatment
We investigated a novel approach for treating ulcerative colitis using lactobacillus acidophilus-derived extracellular vesicles. This method involves encapsulating nanoparticles with siRNA that targets the inflammatory protein TNF-α.
After testing in a model, we found that this system effectively delivers the siRNA to the colon, helping to reduce inflammation and restore gut health. Additionally, it positively influences gut microbiota composition. Overall, our findings suggest this could be a promising treatment strategy for managing ulcerative colitis, though more research is needed to fully understand its effectiveness.
After testing in a model, we found that this system effectively delivers the siRNA to the colon, helping to reduce inflammation and restore gut health. Additionally, it positively influences gut microbiota composition. Overall, our findings suggest this could be a promising treatment strategy for managing ulcerative colitis, though more research is needed to fully understand its effectiveness.
10
No more pain
Most Useful Review
I drink one NATOOSHCHAK capsule in the morning, and during the day, there is no pain or swelling from my 30-year-old chronic colitis. It genuinely works! The enteric-soluble capsule is a significant advantage. Keep it in the refrigerator for longevity. Check expiry dates before ordering. I throw a capsule into milk in the evening and keep it warm. I also recommend having thick kefir in the morning. Wishing you good health.
Probiotics
7
We examined the effects of an engineered probiotic, Saccharomyces boulardii, on colitis-related cancer in a specific mouse model. Over 18 weeks, mice received either the modified probiotic, standard S. boulardii, or a placebo.
While the engineered strain showed promise in binding to inflamed tissue, it ultimately did not significantly lower cancer development linked to colitis. Our findings suggest that more enhancements are necessary to fully unlock its potential against tumorigenesis.
While the engineered strain showed promise in binding to inflamed tissue, it ultimately did not significantly lower cancer development linked to colitis. Our findings suggest that more enhancements are necessary to fully unlock its potential against tumorigenesis.
9.5
Effective for colitis
Most Useful Review
Boulardii was crucial for managing my activated ulcerative colitis, which Gr8-Dophilus alone couldn't handle. Two years ago, a combination of Boulardii, a gluten-free diet, and other products saved my colon from surgery. Unfortunately, my colon deteriorated again, preventing adequate good bacteria growth. Thankfully, Boulardii worked its magic once again.
Slippery Elm
9.5
Lifesaver for colitis
Most Useful Review
A true lifesaver for those with colitis and diarrhoea. Highly recommended!
9.5
Good outcomes experienced
Most Useful Review
Good for ulcers; I have been using it for ulcerative colitis with very positive results.