Culturelle Pro Strength Daily Probiotic

Probiotic strain reduces cholesterol

Cholesterol-lowering effect of Lactobacillus rhamnosus BFE5264 and its influence on the gut microbiome and propionate level in a murine model.

Most Relevant Research

We explored how Lactobacillus rhamnosus BFE5264 affects cholesterol levels using a mouse model on a high-cholesterol diet. This study revealed that this strain significantly reduced serum cholesterol levels while also altering the gut microbiome and increasing beneficial short-chain fatty acids. The findings suggest that L. rhamnosus could regulate cholesterol metabolism in the liver, showing effects similar to those of statin medications. These results highlight the potential of probiotics as a novel approach for managing cholesterol levels.

9.5

Improved digestion

Most Useful Review

This nutritional supplement has greatly helped my digestion. After suffering from diarrhea, I noticed improvement within 10 days of taking the tablets. I found that taking them on an empty stomach an hour before meals enhanced absorption. Overall, my discomfort in the intestines has improved, and I appreciate the product's support in managing my high cholesterol.

Swollen Lymph Nodes details

Reduced stomach swelling

It’s very good. It’s very effective as it alleviates the swelling of the stomach and makes it easier to go to the toilet.

Heartburn details

Miracle for digestion

After struggling with a messed up gut, I started taking these capsules daily, opening them and mixing with yoghurt. Within days, my stomach felt better. I’m thrilled to have found these; I rarely need to take them now—the heartburn and distress from eating are gone.

Menopause details

Probiotic may stabilize estrogen levels

Based on 20 Researches

Supplementation with a Probiotic Formula Having β-Glucuronidase Activity Modulates Serum Estrogen Levels in Healthy Peri- and Postmenopausal Women.

Most Relevant Research

We examined whether a probiotic containing the strain KABP052 could help stabilize estrogen levels in peri- and postmenopausal women. In a thorough randomized, double-blind study, we compared women taking the probiotic to those given a placebo.

Over 12 weeks, those who received KABP052 showed notably higher estradiol and estrone levels, suggesting that this probiotic can effectively modulate estrogen during menopause. This promising finding opens new avenues for using probiotics to support menopausal health.

9.5

IBS relief

Most Useful Review

This stuff gave me my life back! Since menopause three years ago, my IBS symptoms greatly increased. I maintain a plant-based diet, exercise, and sometimes track my food intake. After a food poisoning bout, my doctor recommended Culturelle. Previously, I'd been drinking a probiotic tea that helped somewhat, but it contained only one type of probiotic. Since taking Culturelle daily, my stomach issues no longer hinder me, and I feel much better. It's remarkable how we tolerate IBS symptoms. I’ve had only positive effects from Culturelle and definitely recommend it.

Nausea details

Eating enjoyment restored

Since high school, I've struggled with an upset stomach, to the point where I'd dread meals due to inevitable nausea and other discomforts. After my IBS diagnosis, my doctor recommended probiotics, which I've been taking for two weeks. While I still have occasional issues, it's drastically improved, and I can now enjoy meals again without the constant fear of nausea.

Allergies details

Lactobacillus rhamnosus DNA affects allergies

Based on 28 Researches

Probiotic DNA regulates intestinal Th2 polarization by inducing epithelial cells to produce PD-L1.

Most Relevant Research

We explored how Lactobacillus rhamnosus DNA might affect allergic responses linked to Th2 polarization. Using a specific protocol in mice, we administered LR-DNA daily for five days and observed its impact on intestinal cells. The results showed that LR-DNA increased PD-L1 expression in these cells, which then helped trigger the death of Th2 cells.

Importantly, while we found promising effects, the study suggests that just the DNA from the probiotic—not the live bacteria—was effective in reducing allergic responses.

8.8

Improved sleep quality

Most Useful Review

Good on many fronts, but caution as it may lead to weight gain. Within a week, Lactobacillus rhamnosus (LGG) has significantly improved my leaky gut and food allergies, allowing me a better tolerance of various foods. My sleep quality has enhanced, leaving me well-rested and more energetic in the morning. Additionally, it has reduced mast cell activation syndrome, along with joint inflammation and pain. While it works wonders in those respects, I would advise caution regarding potential rapid weight gain.

Indigestion details

Significantly better digestion

Definitely improves digestion. It helped with bloating and acid indigestion, leaving my stomach feeling more comfortable overall.

Diarrhea details

Inulin reduces neonatal diarrhea incidence

Dietary Inulin Regulated Gut Microbiota and Improved Neonatal Health in a Pregnant Sow Model.

Most Relevant Research

We explored the effect of inulin, a type of dietary fiber, on the health of piglets born to sows during pregnancy. In our study, multiparous sows were divided into two groups. One group received a diet without inulin, while the other group was fed a diet containing 1.6% inulin.

We observed that the inclusion of inulin in the diet significantly reduced the incidences of diarrhea in piglets. Specifically, the sows that consumed inulin had lower levels of urea nitrogen in their colostrum, which correlated with better health outcomes for their piglets. This led to increased survival rates and overall growth of the piglets, providing encouraging evidence that inulin can play an important role in enhancing neonatal health.

Overall, our findings suggest that maternal dietary fiber, particularly inulin, not only supports the health of the sows but also positively influences the wellbeing of their offspring, notably in reducing the risk of diarrhea in newborn piglets.

8.8

Improved gut health

Most Useful Review

The best probiotics for normalising microflora. I give one capsule at night for gastrointestinal issues, which improves my stool. It contains the prebiotic inulin, essential for anyone with gut problems. I take courses myself after antibiotics or diarrhoea.

Back Pain details

It helps with back pain, but doesn't resolve everything. After suffering severe pain and frequent bowel movements for months, I consulted a doctor who suggested Culturelle. I noticed less pain within 48 hours, and my bowel movements improved after four days. While I still have occasional issues, the product allows me to manage better.

Irritable Bowel Syndrome details

Effective treatment for IBS-C

Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial.

Most Relevant Research

We aimed to understand how Lacticaseibacillus rhamnosus IDCC 3201 (RH 3201) affects irritable bowel syndrome with constipation (IBS-C) through a thorough study. In a randomized, double-blind trial, 30 participants took either RH 3201 or a placebo for 8 weeks.

Those taking RH 3201 experienced significant improvements, including fewer bowel discomforts and reduced bloating issues. We also observed an increase in certain beneficial gut bacteria and a link between specific metabolites and symptom relief. Overall, RH 3201 shows promise as an effective treatment for IBS-C.

9.5

Pain relief

Most Useful Review

A lifesaver! I've endured gut-related issues for years. After three months of taking Culturelle, my painful bloating has significantly reduced. Even during a vacation with an unfamiliar diet, I took it daily and experienced no stomach problems, achieving regular bowel movements.

Food Poisoning details

Lacticaseibacillus rhamnosus shows promise

Moderately Effective

Based on 3 Researches

In Vitro and In Vivo Evaluation of Lacticaseibacillus rhamnosus GG and Bifidobacterium lactis Bb12 Against Avian Pathogenic Escherichia coli and Identification of Novel Probiotic-Derived Bioactive Peptides.

Most Relevant Research

We explored the potential of Lacticaseibacillus rhamnosus GG as a probiotic treatment against avian pathogenic E. coli (APEC) in chickens. Our study showed that this probiotic significantly reduced APEC colonization in the chickens' cecum and improved the balance of gut microbiota over a 24-hour period.

Through laboratory evaluations, we detected novel bioactive peptides in the probiotic's culture supernatants, which may contribute to its antibacterial properties. While the results are promising for poultry health, more research is needed to optimize its use in real farming conditions.

3.5

Potential aid post-poisoning

Most Useful Review

It is convenient that it can be stored without refrigeration and remains safe during delivery. However, my analysis did not indicate any increase in beneficial microflora. It may be more effective after food poisoning or following a course of antibiotics.

Constipation details

Probiotic improves IBS-C symptoms

Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial.

Most Relevant Research

We examined the effects of Lacticaseibacillus rhamnosus IDCC 3201 on patients suffering from irritable bowel syndrome with constipation (IBS-C). In a robust study involving 30 participants, we used a randomized, double-blind, placebo-controlled design.

After eight weeks of treatment, the probiotic group reported significant improvements in bowel activities and discomfort linked to constipation. Notably, symptoms like abdominal bloating also improved.

Our findings suggest that this probiotic might help enhance gut health by promoting beneficial microbes and their metabolites.

Life-changing results

Most Useful Review

For almost two years, I've battled painful constipation and tried numerous supplements. Three days in with this product, I've been able to go every single day. It’s completely life-changing. My mind is clearer, my stomach pain is gone, and there's been no negative side effects. I’m so pleased with the improvement.

Pelvic Pain details

One of the best probiotics available, it effectively relieves my pelvic pain and helps maintain regularity. I trust it due to its well-studied strains.

Autoimmune Disorder details