We investigated how a new blend of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001, along with vitamin B6, impacts bloating in patients with irritable bowel syndrome (IBS).
In a study involving 25 IBS patients, we found that those receiving this treatment experienced a significant reduction in bloating, with a 36.35% improvement compared to those on placebo, who actually experienced more bloating.
Overall, this formulation not only alleviated bloating but also eased abdominal pain and improved gut health, showcasing promising results for IBS symptom management.
Read More
8
Probiotic improves gastrointestinal symptoms
Validity and safety of ID-JPL934 in lower gastrointestinal symptom improvement.
We explored how the probiotic ID-JPL934, which includes Lactobacillus johnsonii and Bifidobacterium lactis, can relieve lower gastrointestinal symptoms, particularly bloating.
In a study with 112 participants, we compared those taking the probiotic against a placebo group. Results showed significant improvements in abdominal pain and bloating among those using ID-JPL934.
Moreover, we noted an increase in beneficial bacteria levels after treatment, suggesting that this probiotic might significantly enhance gut health and comfort.
Read More
8
Probiotics reduce bloating post-surgery
Effects of Probiotics Supplementation on Gastrointestinal Symptoms and SIBO after Roux-en-Y Gastric Bypass: a Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.
We explored the impact of probiotic supplementation on gastrointestinal issues following Roux-en-Y gastric bypass. In a well-structured trial, participants were divided into a group receiving Lactobacillus acidophilus and Bifidobacterium lactis and another receiving a placebo.
While both groups showed similar rates of small intestine bacterial overgrowth, those taking the probiotics reported significantly less bloating. They experienced some additional gastrointestinal symptoms but overall felt better in terms of bloating.
Ultimately, the probiotics were effective for managing bloating without affecting SIBO development.
Read More
Most Useful Reviews
9
Quick relief achieved
9 people found this helpful
I've struggled with painful bloating and constipation for months, and after trying Unbloat for a month without results, I turned to Culturelle. In less than a week, it transformed my situation entirely. I’m genuinely impressed and happy with the results. I highly recommend giving this a try!
Read More
9
Immediate improvement noted
8 people found this helpful
I really love this product! I’ve been dealing with severe stomach discomfort and bloating recently, and I noticed an immediate difference within a few days of using it. Eating no longer causes pain, and I feel normal again. This is a great product; I just wish I had discovered it sooner.
Read More
9
Effective relief
8 people found this helpful
Cost-effective and proven! I’ve tried many probiotics to improve my GI system. This is the only one that gives me relief! After a few days, my bloating and discomfort go away. Combined with proper eating, I feel much healthier. My son has also switched to this probiotic as our paediatrician recommended it for its proven results. I couldn’t agree more!
We investigated how cefixime and probiotics impact bloating in patients suffering from functional abdominal bloating (FAB). In a study involving 122 diagnosed patients, we compared three treatment groups: one receiving conventional treatment, a second with cefixime, and a third with probiotics.
Those treated with probiotics and cefixime saw notable improvements in their bloating sensations and abdominal distension compared to conventional methods. Interestingly, while symptoms like abdominal pain and bowel changes improved across all groups, the addition of probiotics and cefixime showed enhanced benefits.
Overall, these findings suggest that incorporating probiotics and cefixime may offer significant support for individuals struggling with bloating.
Read More
9
Lactobacillus reduces IBS bloating symptoms
Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients.
We investigated how a new blend of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001, along with vitamin B6, impacts bloating in patients with irritable bowel syndrome (IBS).
In a study involving 25 IBS patients, we found that those receiving this treatment experienced a significant reduction in bloating, with a 36.35% improvement compared to those on placebo, who actually experienced more bloating.
Overall, this formulation not only alleviated bloating but also eased abdominal pain and improved gut health, showcasing promising results for IBS symptom management.
Read More
9
Probiotics reduce pediatric AAD risk
Probiotics for the Prevention of Pediatric Antibiotic-Associated Diarrhea.
We analyzed data from 23 studies involving nearly 4,000 children to assess how probiotics help prevent antibiotic-associated diarrhea (AAD).
The results showed that those taking probiotics had an 8% incidence of AAD, compared to 19% in the control group, indicating a significant protective effect.
None of the trials documented serious adverse events from the probiotics, but some participants reported mild side effects like gas or bloating. Overall, probiotics such as Lactobacillus rhamnosus seem helpful in reducing AAD in children after antibiotic use.
Read More
9
Probiotics show promise for IBS
Effect of multispecies probiotics on irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial.
We explored the effects of multispecies probiotics, including Lactobacillus rhamnosus, on irritable bowel syndrome (IBS) symptoms like bloating. In a well-structured trial with 49 participants, those taking probiotics saw a significant reduction in IBS symptoms after 4 weeks compared to those on a placebo. Notably, 68% of the probiotics group reported substantial relief, showing promising results in reducing bloating and abdominal discomfort.
These findings suggest that taking multispecies probiotics could be beneficial for those struggling with IBS-related bloating and other symptoms.
Read More
8
Lactobacillus aids iron therapy tolerance
Improved gastrointestinal tolerance and iron status via probiotic use in iron deficiency anaemia patients initiating oral iron replacement: a randomised controlled trial.
We examined how Lactobacillus plantarum 299v impacts patients with iron deficiency anemia who were starting oral iron replacement therapy. In our research with 295 participants, those who took the probiotic alongside their iron therapy reported significantly less bloating and other gastrointestinal issues.
This led to better treatment adherence, with fewer individuals stopping their iron therapy early. Additionally, the probiotic users showed improved iron levels and hemoglobin readings after three months. Overall, Lactobacillus proved effective in easing bloating and supporting gastrointestinal comfort during iron treatment.
I've struggled with painful bloating and constipation for months, and after trying Unbloat for a month without results, I turned to Culturelle. In less than a week, it transformed my situation entirely. I’m genuinely impressed and happy with the results. I highly recommend giving this a try!
Read More
9
Immediate improvement noted
8 people found this helpful
I really love this product! I’ve been dealing with severe stomach discomfort and bloating recently, and I noticed an immediate difference within a few days of using it. Eating no longer causes pain, and I feel normal again. This is a great product; I just wish I had discovered it sooner.
Read More
9
Effective relief
8 people found this helpful
Cost-effective and proven! I’ve tried many probiotics to improve my GI system. This is the only one that gives me relief! After a few days, my bloating and discomfort go away. Combined with proper eating, I feel much healthier. My son has also switched to this probiotic as our paediatrician recommended it for its proven results. I couldn’t agree more!
Read More
9
Rashes disappeared
7 people found this helpful
Delight! I purchased this for a 3-year-old with type 1 diabetes and gastrointestinal issues. Giving half a capsule at night has led to immediate results: rashes on the cheeks disappeared, stools improved, and bloating reduced. The child sleeps better and wakes in a good mood. I enjoy the taste mixed with water. After a long search for effective probiotics, I found this on the recommendation of my paediatric neurologist-nutritionist, Olga Hoffman. It's not cheap, but it truly works.
Read More
9
Effective bloating reduction
5 people found this helpful
Culturelle comes highly recommended by many doctors, and it works as expected. It effectively reduces stomach bloating and you’ll notice a difference in about a month. It’s beneficial for reducing gas and maintaining your digestive system’s order.
Bloating is a common gastrointestinal condition characterized by a sensation of fullness, tightness, or swelling in the abdomen. It often occurs after eating and can be accompanied by visible distension of the belly. This discomfort may be caused by various factors, including excessive gas production, food intolerances, overeating, or certain medical conditions affecting the digestive system. Many people experience bloating occasionally, but when it becomes chronic, it can significantly impact one's quality of life.
Managing bloating typically involves dietary adjustments, such as identifying and avoiding trigger foods, eating smaller meals, and incorporating more fiber into your diet. Staying hydrated and engaging in regular physical activity can also help alleviate symptoms. If bloating is persistent or accompanied by other troubling symptoms like severe pain or changes in bowel habits, it is advisable to consult a healthcare professional for proper evaluation and guidance.
Lactobacillus is a genus of bacteria that plays a crucial role in the fermentation of various foods and is found naturally in the human gut. Known for their probiotic properties, strains of Lactobacillus are commonly utilized in the production of yogurt, sauerkraut, and other fermented products. They are characterized by their rod-shaped structure and ability to convert sugars into lactic acid, which not only helps preserve food but also contributes to the tangy flavor of fermented foods.
In addition to their culinary uses, Lactobacillus bacteria can offer several health benefits. They are known to support gut health by enhancing the balance of beneficial bacteria in the microbiome, potentially aiding in digestion and alleviating symptoms of issues like irritable bowel syndrome (IBS). Regular consumption of Lactobacillus-containing foods or supplements may also bolster the immune system and improve overall digestive health. With a growing interest in gut health, Lactobacillus remains a key player in both dietary and therapeutic contexts.
Lactobacillus, a genus of beneficial bacteria found in many probiotic supplements and fermented foods, has been studied for its potential to alleviate bloating and promote digestive health. Research indicates that certain strains of Lactobacillus can help balance gut microbiota, which may lead to a reduction in bloating and other gastrointestinal discomfort. By improving the digestion of lactose and other foods, these probiotics can enhance nutrient absorption, potentially minimizing gas production and bloating in susceptible individuals.
While individual responses to probiotics can vary, many users report positive effects after incorporating Lactobacillus strains into their diets. Options like yogurt, kefir, and over-the-counter probiotic supplements are popular choices for those looking to harness the power of these helpful bacteria. However, it’s essential to choose the right strain; for example, Lactobacillus rhamnosus and Lactobacillus plantarum have shown promise in various studies. As with any supplement regimen, it’s advisable to consult with a healthcare provider to determine the best approach tailored to your digestive health needs.
Based on user reviews, many individuals report experiencing relief from bloating relatively quickly after starting the supplement. Several users indicate that they felt results within just a few days, with one reviewer noting significant improvement in bloating after only three days of use with a specific strain of probiotics Read Review. Another noted almost immediate results, reporting a significant reduction in gas and bloating shortly after beginning their regimen Read Review.
For many, it seems that noticeable changes can occur within the first week of consistent use. For instance, one user mentioned they were relieved of a lifelong struggle with bloating after just a week of taking the supplement Read Review. Another indicated that after taking the product on an empty stomach each morning, symptoms vanished completely Read Review. Overall, while individual results may vary, it's common for users to report improvements in their bloating within a short time frame, ranging from days to a week.
Probiotics, particularly those containing strains like Lactobacillus, have garnered considerable scientific backing for their role in alleviating bloating. Research has shown that probiotics can improve symptoms of functional abdominal bloating, especially in patients treated with cefixime and conventional therapies, leading to significant relief from bloating sensations and abdominal distension [1]. Additionally, Lactobacillus plantarum has demonstrated effectiveness in reducing bloating for individuals undergoing iron therapy, showing improved gastrointestinal comfort as well [2]. These findings point towards a promising role of probiotics in managing bloating symptoms.
Other studies reinforce these conclusions, highlighting the efficacy of various probiotic strains in treating bloating, particularly in individuals with irritable bowel syndrome (IBS). In a review of 81 randomized trials, specific strains were identified as beneficial for reducing abdominal bloating [4]. Additionally, Lactobacillus rhamnosus has been specifically noted for providing moderate relief for bloating [17]. Furthermore, combined interventions using inulin have also shown potential in reducing bloating symptoms, especially in IBS patients [23]. Collectively, this body of research provides substantial evidence supporting the use of probiotics and targeted supplements for effectively managing bloating.
Based on user reviews, many individuals have reported significant improvements in symptoms related to bloating and digestive issues after using the product. For some users, relief came quickly; one reviewer noted that their bloating improved within just three days of taking the specific strain of probiotics Read Review. Another user experienced almost immediate results, with a significant reduction in gas and bloating after starting their regimen Read Review.
In addition to fast relief, many users report that continued use over several weeks leads to long-term benefits. One individual mentioned being freed from a lifelong struggle with bloating in just a week of consistent use Read Review. Another user stated that their gut issues improved significantly over three months, resulting in fewer painful episodes and maintained regular bowel movements even during dietary changes Read Review. While results can vary from person to person, the consensus among users points to a notable decrease in gastrointestinal discomfort for many.
Based on user reviews, combining this supplement with other products yielded mixed results. Some users experienced enhanced results when integrating this probiotic into their routine. For instance, one user noted that after incorporating the product, their bloating diminished significantly, allowing them to feel more comfortable in social situations Read Review. Another individual reported that their gut and digestive system benefited substantially from using the supplement in conjunction with guidance from a healthcare professional, specifically mentioning that they would consult their doctor if needed for any additional support Read Review.
However, not all users found success when combining it with other supplements. Some expressed that their bloating issues persisted or even worsened after trying the product, suggesting that individual responses may vary widely and that the effectiveness of probiotics might differ depending on the specific combination used Read Review. This highlights the importance of personalized approaches to supplement use, especially for those dealing with persistent bloating or digestive issues.
Based on user reviews, many consumers found success with specific doses of Lactobacillus for alleviating bloating. For instance, one user reported that giving half a capsule to a child at night resulted in immediate improvements in bloating and overall gastrointestinal health Read Review. Additionally, others noted positive results from daily doses, with one user mentioning that they began experiencing reduced bloating just days after starting their routine Read Review.
Several reviews indicated that consistency is key, as regular use seemed to yield better results in users' digestive health. One review highlighted that after using the product daily, the user saw a significant decrease in bloating Read Review. While there appears to be variance in individual experiences, many users emphasized that appropriate dosages, whether half capsules or regular full doses, contributed positively to reducing their bloating symptoms.
9
Bloating improved
1 people found this helpful
After taking this effective LGG strain, my bloating improved significantly within three days. Despite trying a complex strain, this single strain worked better for me.
9
Immediate results
1 people found this helpful
Almost immediate results! My gas and bloating have reduced significantly. Thank you.
9
Bloating gone
3 people found this helpful
I highly recommend it to anyone suffering from bloating! Within a week, I was relieved of a lifelong struggle with this issue.
9
Bloating resolved
4 people found this helpful
Since pregnancy, I suffered from persistent eructation after eating, which was quite bothersome. However, after taking this remedy on an empty stomach each morning, my symptoms vanished! Now, my gastrointestinal system feels excellent, and my stools are regular. I also noted a special series for babies, which can help with colic and bloating, leading to better sleep for parents.
9
Bloating reduced
2 people found this helpful
This has been a lifesaver! After struggling with gut issues for years, I've been taking Culturelle for three months, and my painful bloating has greatly lessened. Even while on vacation and adapting to new foods, I maintained regular bowel movements and did not experience any stomach problems.
8
Bloating relief
3 people found this helpful
Although it might be slightly pricey, the results are exceptional. According to a YouTube pharmacist, the effectiveness of lactic acid bacteria varies among individuals. After taking this product, my bloating and gas issues greatly decreased, making social situations more comfortable. I had not realised these problems were linked to lactic acid bacteria. My digestion has also improved significantly, and I plan to continue using it, though I will consult my doctor if needed.
0
Worsened bloating
I bought it to help with digestion, but my bloating actually worsened. It didn't work for me personally.
9
Rashes disappeared
7 people found this helpful
Delight! I purchased this for a 3-year-old with type 1 diabetes and gastrointestinal issues. Giving half a capsule at night has led to immediate results: rashes on the cheeks disappeared, stools improved, and bloating reduced. The child sleeps better and wakes in a good mood. I enjoy the taste mixed with water. After a long search for effective probiotics, I found this on the recommendation of my paediatric neurologist-nutritionist, Olga Hoffman. It's not cheap, but it truly works.
9
Less bloating
1 people found this helpful
Initially sceptical, I began taking Culturelle probiotics for better digestion. Within days, my bloating reduced, and I felt lighter. I appreciate that it's suitable for my vegetarian lifestyle.
9
Excellent for bloating
1 people found this helpful
I take these probiotics daily for bloating and gut health. Culturelle works well for me and aids in bowel movements.
9
Cefixime and probiotics enhance bloating relief
Impact of cefixime and probiotics on functional abdominal bloating: a pilot study.
We investigated how cefixime and probiotics impact bloating in patients suffering from functional abdominal bloating (FAB). In a study involving 122 diagnosed patients, we compared three treatment groups: one receiving conventional treatment, a second with cefixime, and a third with probiotics.
Those treated with probiotics and cefixime saw notable improvements in their bloating sensations and abdominal distension compared to conventional methods. Interestingly, while symptoms like abdominal pain and bowel changes improved across all groups, the addition of probiotics and cefixime showed enhanced benefits.
Overall, these findings suggest that incorporating probiotics and cefixime may offer significant support for individuals struggling with bloating.
8
Lactobacillus aids iron therapy tolerance
Improved gastrointestinal tolerance and iron status via probiotic use in iron deficiency anaemia patients initiating oral iron replacement: a randomised controlled trial.
We examined how Lactobacillus plantarum 299v impacts patients with iron deficiency anemia who were starting oral iron replacement therapy. In our research with 295 participants, those who took the probiotic alongside their iron therapy reported significantly less bloating and other gastrointestinal issues.
This led to better treatment adherence, with fewer individuals stopping their iron therapy early. Additionally, the probiotic users showed improved iron levels and hemoglobin readings after three months. Overall, Lactobacillus proved effective in easing bloating and supporting gastrointestinal comfort during iron treatment.
7
Probiotics offer selective benefits
Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis.
We explored the effectiveness of various probiotic strains and mixtures for treating bloating in individuals with irritable bowel syndrome (IBS). Our analysis comprised data from 81 randomized controlled trials, involving 9,253 participants.
While multiple probiotics proved beneficial for specific IBS symptoms, only three strains and two mixtures demonstrated effectiveness in alleviating abdominal bloating.
Notably, while some probiotics showed promise, results varied, indicating that not all strains are equally effective for every symptom. Further investigations are required to strengthen these findings.
8
L. rhamnosus may reduce bloating
Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial.
We conducted a randomized study focusing on patients suffering from irritable bowel syndrome with constipation (IBS-C). Our aim was to see how adding a specific food supplement that includes inulin, choline, and silymarin could help alleviate bloating and other IBS symptoms compared to a standard constipation diet alone.
After eight weeks of treatment, we observed a notable improvement in bloating severity. Specifically, the addition of the supplement led to a 34.8% reduction in bloating symptoms among participants who used it in conjunction with their diet. This indicates that inulin, as part of this combination, may have a positive effect on alleviating bloating.
However, while stool frequency and consistency did show some improvement, these results were not statistically significant when comparing the two groups. Therefore, while there are clear benefits to including inulin with other ingredients for bloating relief, we must recognize that inulin’s isolated effects are part of a larger picture.
References
Salama RI, Tawfik S, Emara MH, Abdelkader AH. Impact of cefixime and probiotics on functional abdominal bloating: a pilot study. Prz Gastroenterol. 2024;16:408. doi:10.5114/pg.2024.142141
Koker G, Sahinturk Y, Ozcelik Koker G, Coskuner MA, Eren Durmus M, et al. Improved gastrointestinal tolerance and iron status via probiotic use in iron deficiency anaemia patients initiating oral iron replacement: a randomised controlled trial. Br J Nutr. 2024;132:1308. doi:10.1017/S0007114524002757
Yang H, Lan W, Luo C, Huang Q, Zhong Z, et al. improves postoperative bloating and hard stools by modulating intestinal microbiota in patients with congenital heart disease: a randomized controlled trial. Food Funct. 2024;15:2090. doi:10.1039/d3fo05452g
Xie P, Luo M, Deng X, Fan J, Xiong L. Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis. Nutrients. 2023;15. doi:10.3390/nu15173856
Vorobieva OA, Shih EV, Drozdov VN, Shikh NV. [The results of the use of a combined probiotic ( and spp. ВB-12) in children with gastrointestinal and skin manifestations of food allergy]. Vopr Pitan. 2023;92:79. doi:10.33029/0042-8833-2023-92-3-79-86
Deleemans JM, Gajtani Z, Baydoun M, Reimer RA, Piedalue KA, et al. The Use of Prebiotic and Probiotic Interventions for Treating Gastrointestinal and Psychosocial Health Symptoms in Cancer Patients and Survivors: A Systematic Review. Integr Cancer Ther. 2021;20:15347354211061733. doi:10.1177/15347354211061733
Oh YJ, Nam K, Kim Y, Lee SY, Kim HS, et al. Effect of a Nutritionally Balanced Diet Comprising Whole Grains and Vegetables Alone or in Combination with Probiotic Supplementation on the Gut Microbiota. Prev Nutr Food Sci. 2021;26:121. doi:10.3746/pnf.2021.26.2.121
Shin CM, Choi YJ, Lee DH, Moon JS, Kim TY, et al. Validity and safety of ID-JPL934 in lower gastrointestinal symptom improvement. Sci Rep. 2021;11:13046. doi:10.1038/s41598-021-92007-3
Wagner NRF, Ramos MRZ, de Oliveira Carlos L, da Cruz MRR, Taconeli CA, et al. Effects of Probiotics Supplementation on Gastrointestinal Symptoms and SIBO after Roux-en-Y Gastric Bypass: a Prospective, Randomized, Double-Blind, Placebo-Controlled Trial. Obes Surg. 2021;31:143. doi:10.1007/s11695-020-04900-x
Fatani A, Vaher K, Rivero-Mendoza D, Alabasi K, Dahl WJ. Fermented soy supplementation improves indicators of quality of life: a randomized, placebo-controlled, double-blind trial in adults experiencing heartburn. BMC Res Notes. 2020;13:364. doi:10.1186/s13104-020-05205-z
Maixent JM, Pons O, Sennoune SR, Sadrin S. Clinical effects of Lactobacillus strains as probiotics in the treatment of irritable bowel syndrome. Results from the LAPIBSS trial: Future objectives. Cell Mol Biol (Noisy-le-grand). 2020;66:211.
Bonfrate L, Di Palo DM, Celano G, Albert A, Vitellio P, et al. Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients. Eur J Clin Invest. 2020;50:e13201. doi:10.1111/eci.13201
Sadrin S, Sennoune S, Gout B, Marque S, Moreau J, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis. 2020;52:534. doi:10.1016/j.dld.2019.12.009
Wang MC, Zaydi AI, Lin WH, Lin JS, Liong MT, et al. Putative Probiotic Strains Isolated from Kefir Improve Gastrointestinal Health Parameters in Adults: a Randomized, Single-Blind, Placebo-Controlled Study. Probiotics Antimicrob Proteins. 2020;12:840. doi:10.1007/s12602-019-09615-9
Lai HH, Chiu CH, Kong MS, Chang CJ, Chen CC. Probiotic : Effective for Managing Childhood Diarrhea by Altering Gut Microbiota and Attenuating Fecal Inflammatory Markers. Nutrients. 2019;11. doi:10.3390/nu11051150
Vitellio P, Celano G, Bonfrate L, Gobbetti M, Portincasa P, et al. Effects of and on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study. Nutrients. 2019;11. doi:10.3390/nu11040886
Kwon H, Nam EH, Kim H, Jo H, Bang WY, et al. Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial. Sci Rep. 2024;14:22384. doi:10.1038/s41598-024-72887-x
Hayes SR, Vargas AJ. Probiotics for the Prevention of Pediatric Antibiotic-Associated Diarrhea. Explore (NY). 2016;12:463. doi:10.1016/j.explore.2016.08.015
Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, et al. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev. 2015. doi:10.1002/14651858.CD004827.pub4
Hauser G, Salkic N, Vukelic K, JajacKnez A, Stimac D. Probiotics for standard triple Helicobacter pylori eradication: a randomized, double-blind, placebo-controlled trial. Medicine (Baltimore). 2015;94:e685. doi:10.1097/MD.0000000000000685
Yoon JS, Sohn W, Lee OY, Lee SP, Lee KN, et al. Effect of multispecies probiotics on irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Gastroenterol Hepatol. 2014;29:52. doi:10.1111/jgh.12322
Molin G. Probiotics in foods not containing milk or milk constituents, with special reference to Lactobacillus plantarum 299v. Am J Clin Nutr. 2001;73:380S. doi:10.1093/ajcn/73.2.380s
Bărboi OB, Chirilă I, Ciortescu I, Anton C, Drug VL. Inulin, Choline and Silymarin in the Treatment of Irritable Bowel Syndrome with Constipation-Randomized Case-Control Study. J Clin Med. 2022;11. doi:10.3390/jcm11082248
Iriondo-DeHond M, Iriondo-DeHond A, Herrera T, Fernández-Fernández AM, Sorzano COS, et al. Sensory Acceptance, Appetite Control and Gastrointestinal Tolerance of Yogurts Containing Coffee-Cascara Extract and Inulin. Nutrients. 2020;12. doi:10.3390/nu12030627
Baştürk A, Artan R, Yılmaz A. Efficacy of synbiotic, probiotic, and prebiotic treatments for irritable bowel syndrome in children: A randomized controlled trial. Turk J Gastroenterol. 2016;27:439. doi:10.5152/tjg.2016.16301
Major G, Pritchard S, Murray K, Alappadan JP, Hoad CL, et al. Colon Hypersensitivity to Distension, Rather Than Excessive Gas Production, Produces Carbohydrate-Related Symptoms in Individuals With Irritable Bowel Syndrome. Gastroenterology. 2017;152:124. doi:10.1053/j.gastro.2016.09.062
Pilipenko VI, Teplyuk DA, Shakhovskaya AK, Isakov VA, Vorobyova VM, et al. [Using a multicomponent functional food in IBS patients with constipation a comparative controlled study]. Vopr Pitan. 2016;85:84.
Pilipenko VI, Teplyuk DA, Shakhovskaya AK, Isakov VA, Vorobyova VM, et al. [Dry jelly concentrate with vitamins and dietary fiber in patients with IBS with constipation: a comparative controlled study]. Vopr Pitan. 2015;84:83.
Holscher HD, Doligale JL, Bauer LL, Gourineni V, Pelkman CL, et al. Gastrointestinal tolerance and utilization of agave inulin by healthy adults. Food Funct. 2014;5:1142. doi:10.1039/c3fo60666j
Koecher KJ, Noack JA, Timm DA, Klosterbuer AS, Thomas W, et al. Estimation and interpretation of fermentation in the gut: coupling results from a 24 h batch in vitro system with fecal measurements from a human intervention feeding study using fructo-oligosaccharides, inulin, gum acacia, and pea fiber. J Agric Food Chem. 2014;62:1332. doi:10.1021/jf404688n
Costabile A, Kolida S, Klinder A, Gietl E, Bäuerlein M, et al. A double-blind, placebo-controlled, cross-over study to establish the bifidogenic effect of a very-long-chain inulin extracted from globe artichoke (Cynara scolymus) in healthy human subjects. Br J Nutr. 2010;104:1007. doi:10.1017/S0007114510001571
Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc. 2010;110:865. doi:10.1016/j.jada.2010.03.025
Ripoll C, Flourié B, Megnien S, Hermand O, Janssens M. Gastrointestinal tolerance to an inulin-rich soluble roasted chicory extract after consumption in healthy subjects. Nutrition. 2010;26:799. doi:10.1016/j.nut.2009.07.013
Bruhwyler J, Carreer F, Demanet E, Jacobs H. Digestive tolerance of inulin-type fructans: a double-blind, placebo-controlled, cross-over, dose-ranging, randomized study in healthy volunteers. Int J Food Sci Nutr. 2009;60:165. doi:10.1080/09637480701625697