Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.8
USERS' SCORE
Good
Based on 4 Reviews
8.5
Supplement Facts
Serving Size: One (1) Capsule
Amount Per Serving
%DV
Calories
0
Total Carbohydrate
0 g
0%+
Total Sugars
0 g
**
Incl. 0 g Added Sugars
0%+
Lactobacillus rhamnosus GG
40 mg (10 billion CFUs)
**
Inulin (Chicory Root Extract)
200 mg
**
Top Medical Research Studies
9
We investigated the effects of Limosilactobacillus fermentum (L. fermentum) KBL674 on vaginal candidiasis in a mouse model. This strain inhibited the growth of Candida albicans and significantly decreased infection symptoms. Notably, the oral intake of L. fermentum KBL674 influenced both vaginal and gut microbiome health, promoting beneficial bacteria that seemed to correlate with reduced C. albicans levels. Thus, L. fermentum KBL674 shows promise for managing vaginal candidiasis by enhancing gut microbiome diversity and lowering fungal burden.
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9
We conducted a rigorous study to investigate the impact of lactobacillus probiotics on pregnant women suffering from vaginal candidiasis. In this double-blind, placebo-controlled trial involving 78 participants, we administered a probiotic for eight weeks.
Our results highlighted significant benefits, with the probiotics maintaining microbiota stability in the vagina and gut, unlike the placebo group. Participants taking probiotics showed less variation in their microbiota, which is crucial for overall health. While the treatment showed promise in preserving microbiota composition, individual experiences may vary.
Our results highlighted significant benefits, with the probiotics maintaining microbiota stability in the vagina and gut, unlike the placebo group. Participants taking probiotics showed less variation in their microbiota, which is crucial for overall health. While the treatment showed promise in preserving microbiota composition, individual experiences may vary.
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4
Lactobacillus shows promise for candidiasis
We assessed how well Lactobacillus plantarum P 17630 works against vaginal candidiasis compared to traditional antifungal treatments like miconazole. In a controlled trial, women with candidiasis took either Lactobacillus capsules or miconazole capsules for several days. Results showed that both treatments reduced vaginitis symptoms over time, with no significant differences. Importantly, Lactobacillus treatment did not lead to any adverse effects and may foster healthier vaginal flora in the long run, potentially decreasing recurring infections.
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Most Useful Reviews
9
Highly effective treatment
3 people found this helpful
Solid five! This probiotic truly works 100%. It's incredibly popular in the USA, available in every pharmacy. During my time in America, I learned about it. A local doctor prescribed it alongside my antibiotic therapy to prevent dysbiosis. I always take two capsules between doses of antibiotics, maintaining order in my body and intestines. Additionally, after taking it, Candidiasis remains at bay for a long time.
Read More
9
Significant improvement
2 people found this helpful
Wonderful! I had fungi, women's infections, and Candidiasis, and I benefited tremendously from this treatment.
Read More
9
No dysbiosis experienced
Excellent! I took this while on antibiotics, with no dysbiosis occurring. My body functions perfectly, and Candidiasis did not trouble me, which is crucial. These probiotics are very popular.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.8
- All Researches
9.5
This study looked at Lactobacillus gasseri VHProbi E09, a strain shown to effectively inhibit harmful bacteria like Gardnerella vaginalis and Candida albicans, key players in vaginitis. We found that this strain could cut the growth of both pathogens by an impressive 99%, while also preventing their attachment to vaginal cells.
What’s exciting is the potential of L. gasseri VHProbi E09 as a probiotic for improving vaginal health, either taken orally or applied directly. However, more research is needed to fully explore its effects and effectiveness in restoring balance in the vaginal ecosystem.
What’s exciting is the potential of L. gasseri VHProbi E09 as a probiotic for improving vaginal health, either taken orally or applied directly. However, more research is needed to fully explore its effects and effectiveness in restoring balance in the vaginal ecosystem.
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9
Identified lactobacillus metabolites inhibit Candida
Through innovative techniques like genome-scale metabolic modeling and metagenomic sequencing, we discovered the role of specific lactobacillus strains in combating vulvovaginal candidiasis (VVC).
Our analysis of 159 strains showed that many have inhibitory effects on Candida, altering its metabolism through key metabolites like L-lactate and formate. Interestingly, we found a positive link between the presence of these beneficial strains and lower Candida levels in vaginal samples.
This research informs future strategies focused on enhancing vaginal health by utilizing these powerful strains and their metabolites to hinder candidiasis.
Our analysis of 159 strains showed that many have inhibitory effects on Candida, altering its metabolism through key metabolites like L-lactate and formate. Interestingly, we found a positive link between the presence of these beneficial strains and lower Candida levels in vaginal samples.
This research informs future strategies focused on enhancing vaginal health by utilizing these powerful strains and their metabolites to hinder candidiasis.
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9
We investigated the potential of a newly isolated probiotic, AJCR4, to combat oral candidiasis, a common infection, particularly among immunocompromised individuals. AJCR4 showed strong antifungal effects against both free and biofilm forms of Candida, with impressive results in reducing viable cells in lab tests. In specific biofilms, we observed over 2-log reductions in cell counts. This promising performance suggests that AJCR4 could serve as an effective alternative strategy for treating difficult oral candidiasis cases, especially recurrent infections.
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9
We investigated the effects of a novel fermentation broth called VAGINNE on vulvovaginal candidiasis (VVC), a common condition affecting many women. Using a mouse model, we found that VAGINNE not only boosted beneficial bacteria but also suppressed the growth of Candida, promoting a healthier vaginal environment.
Additionally, VAGINNE significantly decreased inflammation markers, which is essential for tissue health. This promising approach suggests VAGINNE could be a valuable alternative to traditional antifungals, especially for women facing drug resistance or side effects from standard treatments.
Additionally, VAGINNE significantly decreased inflammation markers, which is essential for tissue health. This promising approach suggests VAGINNE could be a valuable alternative to traditional antifungals, especially for women facing drug resistance or side effects from standard treatments.
Read More
9
We explored how combining oral probiotics with standard antifungal treatment affects vulvovaginal candidiasis (VVC). In a randomized controlled trial involving 60 patients, we compared results between those receiving antifungal medication alone and those receiving it alongside probiotics.
The results were promising! Participants who took probiotics showed better clinical and mycological outcomes, along with a reduced rate of relapse compared to those on antifungal treatment alone. This suggests that probiotics may be a valuable addition to VVC management.
The results were promising! Participants who took probiotics showed better clinical and mycological outcomes, along with a reduced rate of relapse compared to those on antifungal treatment alone. This suggests that probiotics may be a valuable addition to VVC management.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Highly effective treatment
3 people found this helpful
Solid five! This probiotic truly works 100%. It's incredibly popular in the USA, available in every pharmacy. During my time in America, I learned about it. A local doctor prescribed it alongside my antibiotic therapy to prevent dysbiosis. I always take two capsules between doses of antibiotics, maintaining order in my body and intestines. Additionally, after taking it, Candidiasis remains at bay for a long time.
Read More
9
Significant improvement
2 people found this helpful
Wonderful! I had fungi, women's infections, and Candidiasis, and I benefited tremendously from this treatment.
Read More
9
No dysbiosis experienced
Excellent! I took this while on antibiotics, with no dysbiosis occurring. My body functions perfectly, and Candidiasis did not trouble me, which is crucial. These probiotics are very popular.
Read More
6
Need more time
I find this probiotic to be good but require more time to assess its effectiveness. It was recommended to me for Candidiasis.
Read More
Frequently Asked Questions
9
Highly effective treatment
3 people found this helpful
Solid five! This probiotic truly works 100%. It's incredibly popular in the USA, available in every pharmacy. During my time in America, I learned about it. A local doctor prescribed it alongside my antibiotic therapy to prevent dysbiosis. I always take two capsules between doses of antibiotics, maintaining order in my body and intestines. Additionally, after taking it, Candidiasis remains at bay for a long time.
9
Significant improvement
2 people found this helpful
Wonderful! I had fungi, women's infections, and Candidiasis, and I benefited tremendously from this treatment.
6
Need more time
I find this probiotic to be good but require more time to assess its effectiveness. It was recommended to me for Candidiasis.
9
No dysbiosis experienced
Excellent! I took this while on antibiotics, with no dysbiosis occurring. My body functions perfectly, and Candidiasis did not trouble me, which is crucial. These probiotics are very popular.
9
We explored how combining oral probiotics with standard antifungal treatment affects vulvovaginal candidiasis (VVC). In a randomized controlled trial involving 60 patients, we compared results between those receiving antifungal medication alone and those receiving it alongside probiotics.
The results were promising! Participants who took probiotics showed better clinical and mycological outcomes, along with a reduced rate of relapse compared to those on antifungal treatment alone. This suggests that probiotics may be a valuable addition to VVC management.
The results were promising! Participants who took probiotics showed better clinical and mycological outcomes, along with a reduced rate of relapse compared to those on antifungal treatment alone. This suggests that probiotics may be a valuable addition to VVC management.
9
LM1215 shows promise for VVC prevention
We observed three specific strains of Lactobacillus, namely LM1203, LM1209, and LM1215, that displayed promising results in inhibiting vulvovaginal candidiasis (VVC). Isolated from healthy women, these strains significantly reduced the growth of harmful pathogens.
In addition, LM1215 showed remarkable ability to disrupt biofilms and induce cellular damage against these pathogens. Our findings suggest that LM1215 is not only effective but also safe, positioning it as a viable probiotic option for preventing VVC and bacterial vaginosis.
In addition, LM1215 showed remarkable ability to disrupt biofilms and induce cellular damage against these pathogens. Our findings suggest that LM1215 is not only effective but also safe, positioning it as a viable probiotic option for preventing VVC and bacterial vaginosis.
9
We investigated the effects of a novel fermentation broth called VAGINNE on vulvovaginal candidiasis (VVC), a common condition affecting many women. Using a mouse model, we found that VAGINNE not only boosted beneficial bacteria but also suppressed the growth of Candida, promoting a healthier vaginal environment.
Additionally, VAGINNE significantly decreased inflammation markers, which is essential for tissue health. This promising approach suggests VAGINNE could be a valuable alternative to traditional antifungals, especially for women facing drug resistance or side effects from standard treatments.
Additionally, VAGINNE significantly decreased inflammation markers, which is essential for tissue health. This promising approach suggests VAGINNE could be a valuable alternative to traditional antifungals, especially for women facing drug resistance or side effects from standard treatments.
7
We examined how effective probiotics are for treating vulvovaginal candidiasis, a common vaginal infection. By analyzing six randomized control trials, we compared the effects of probiotics to placebo treatments.
While we found that probiotics did not significantly differ from placebos in the rate of positive cultures, they did show a marked reduction in recurrence rates. This suggests that while they may not eliminate the infection outright, probiotics could help lessen the chance of it coming back, offering a possible alternative treatment.
While we found that probiotics did not significantly differ from placebos in the rate of positive cultures, they did show a marked reduction in recurrence rates. This suggests that while they may not eliminate the infection outright, probiotics could help lessen the chance of it coming back, offering a possible alternative treatment.
References
- Hu T, Meng Y, Zhao C, Sheng D, Yang S, et al. Genome-scale metabolic modeling reveals specific vaginal strains and their metabolites as key inhibitors of . Microbiol Spectr. 2025. doi:10.1128/spectrum.02984-24
- Nachum Z, Suleiman A, Colodner R, Battino S, Wattad M, et al. Oral Probiotics to Prevent Recurrent Vulvovaginal Infections During Pregnancy-Multicenter Double-Blind, Randomized, Placebo-Controlled Trial. Nutrients. 2025;17. doi:10.3390/nu17030460
- Rajão A, Silva JPN, Almeida-Nunes DL, Rompante P, Rodrigues CF, et al. AJCR4: A Potential Probiotic in the Fight Against Oral spp. Biofilms. Int J Mol Sci. 2025;26. doi:10.3390/ijms26020638
- Horng HC, Xu JW, Kuo YS, Chen YS, Chiu YH, et al. Dual Mechanisms of Action: Anti-Candida and Anti-Inflammatory Potential of Fermentation Broth in Treating Vulvovaginal Candidiasis. J Fungi (Basel). 2024;11. doi:10.3390/jof11010018
- Thekho AJ, Mendiratta V, Garg T, Kaur R, Yadav V. Role of Probiotic in Vulvovaginal Candidiasis: A Randomised Controlled Non-blinded Trial from India. Indian J Dermatol. 2024;69:422. doi:10.4103/ijd.ijd_193_24
- Bae WY, Lee YJ, Jo S, Shin SL, Kim TR, et al. Effects of LM1215 on and . Yonsei Med J. 2024;65:727. doi:10.3349/ymj.2023.0490
- Jang SJ, Jo EJ, Lee C, Cho BR, Shin YJ, et al. Limosilactobacillus fermentum KBL674 Alleviates Vaginal Candidiasis. Probiotics Antimicrob Proteins. 2024. doi:10.1007/s12602-024-10403-3
- Ferreira RLPS, Nova BGV, Carmo MS, Abreu AG. Mechanisms of action of Lactobacillus spp. in the treatment of oral candidiasis. Braz J Biol. 2024;84:e282609. doi:10.1590/1519-6984.282609
- Vazquez-Munoz R, Thompson A, Sobue T, Dongari-Bagtzoglou A. is a dominant in the murine oral mucosa and has chitinase activity that compromises fungal cell wall integrity. mBio. 2024;15:e0241624. doi:10.1128/mbio.02416-24
- Zuñiga Vinueza AM. Probiotics for the Prevention of Vaginal Infections: A Systematic Review. Cureus. 2024;16:e64473. doi:10.7759/cureus.64473
- Zhang J, Li K, Cao T, Duan Z. Characterization of a Lactobacillus gasseri strain as a probiotic for female vaginitis. Sci Rep. 2024;14:14426. doi:10.1038/s41598-024-65550-y
- Elsayes SA, El Attar MS, ElHadary A, Aboulela AG, Essawy MM, et al. Antimycotic prophylaxis with multispecies probiotics against oral candidiasis in new complete denture wearers: A randomized clinical trial. J Prosthet Dent. 2024. doi:10.1016/j.prosdent.2024.05.018
- Zahedifard T, Khadivzadeh T, Rakhshkhorshid M. The Role of Probiotics in the Treatment of Vulvovaginal Candidiasis: A Systematic Review and Meta-Analysis. Ethiop J Health Sci. 2023;33:881. doi:10.4314/ejhs.v33i5.18
- Ang XY, Roslan NS, Ahmad N, Yusof SM, Abdullah N, et al. Lactobacillus probiotics restore vaginal and gut microbiota of pregnant women with vaginal candidiasis. Benef Microbes. 2023;14:421. doi:10.1163/18762891-20220103
- Bertarello C, Savio D, Morelli L, Bouzalov S, Davidova D, et al. Efficacy and safety of Lactobacillus plantarum P 17630 strain soft vaginal capsule in vaginal candidiasis: a randomized non-inferiority clinical trial. Eur Rev Med Pharmacol Sci. 2024;28:384. doi:10.26355/eurrev_202401_34927
- Faustino M, Pereira JO, Pereira AM, Oliveira AS, Ferreira CMH, et al. Vaginal prevention of Candida albicans: synergistic effect of lactobacilli and mannan oligosaccharides (MOS). Appl Microbiol Biotechnol. 2024;108:73. doi:10.1007/s00253-023-12909-2
