Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 39 Researches
7.9
USERS' SCORE
Good
Based on 20 Reviews
8.4
Supplement Facts
Serving Size: 1 tablet
Amount Per Serving
%DV
Vitamin B6 (as pyridoxine HCl)
2 mg
118%
Folate (as folic acid)
400 mcg DFE
100%
Vitamin B12 (as methylcobalamin)
1000 mcg
41667%
Top Medical Research Studies
9.5
We explored the case of a 23-month-old boy suffering from severe pancytopenia linked to Imerslund-Gräsbeck syndrome, a rare condition caused by an inability to absorb vitamin B12. Upon diagnosis, the boy received vitamin B12 replacement therapy, which effectively addressed his symptoms and improved his health.
This case highlights the significance of early detection and treatment of IGS to avoid potential neurological damage. It's crucial to recognize this condition, even when neurological symptoms are absent, to provide timely care.
This case highlights the significance of early detection and treatment of IGS to avoid potential neurological damage. It's crucial to recognize this condition, even when neurological symptoms are absent, to provide timely care.
Read More
9.5
We focused on how oral vitamin B12 could help those with pernicious anemia, where absorption is usually impaired. Participants diagnosed with vitamin B12 deficiency due to this condition took a daily dose of 1000 μg of oral cyanocobalamin.
Over a year, an impressive 88.5% of them no longer showed deficiency after just one month, with significant improvements in vitamin B12 levels and related biological markers. Importantly, these benefits lasted throughout the study period.
Over a year, an impressive 88.5% of them no longer showed deficiency after just one month, with significant improvements in vitamin B12 levels and related biological markers. Importantly, these benefits lasted throughout the study period.
Read More
9.5
We observed a compelling case involving a 32-year-old pregnant woman who experienced severe anemia during her pregnancy. This specific type of anemia, known as sideroblastic anemia, is quite rare in expectant mothers. The patient had been feeling weak and had heart palpitations for two weeks when she came to the emergency room.
Testing revealed she had an alarming hemoglobin level of just 4.2 g/dl, indicating severe anemia, along with a notably low reticulocyte count. What made this case particularly interesting was her history of recurrent anemia, which occurred exclusively during her pregnancies.
Upon examining her bone marrow, doctors found numerous ring sideroblasts, which confirmed the diagnosis of sideroblastic anemia. Further investigation uncovered extremely low levels of pyridoxine, or vitamin B6, in her system. After administering vitamin B6 replacement therapy, her hemoglobin levels improved significantly without the need for blood transfusions, highlighting the vitamin’s role in managing this type of anemia during pregnancy.
Testing revealed she had an alarming hemoglobin level of just 4.2 g/dl, indicating severe anemia, along with a notably low reticulocyte count. What made this case particularly interesting was her history of recurrent anemia, which occurred exclusively during her pregnancies.
Upon examining her bone marrow, doctors found numerous ring sideroblasts, which confirmed the diagnosis of sideroblastic anemia. Further investigation uncovered extremely low levels of pyridoxine, or vitamin B6, in her system. After administering vitamin B6 replacement therapy, her hemoglobin levels improved significantly without the need for blood transfusions, highlighting the vitamin’s role in managing this type of anemia during pregnancy.
Read More
Most Useful Reviews
7.5
Calmer emotions
18 people found this helpful
B12 is essential for maintaining good iron stores, and its active form is well absorbed. I noticed that low B12 can lead to irritability and aggression, so I supplement with B vitamins, especially B12 and magnesium glycinate, which helps me feel calmer and reduces anxiety. I find that B vitamins are a necessity for me. Although this product includes inactive forms of B6 and folic acid, its effectiveness for hair health is excellent. The tablets taste unpleasant but dissolve quickly.
Read More
9
Wonderful effect
14 people found this helpful
Amazing! I have pernicious anemia and these tablets are wonderful for me. I love that they do not contain cyanocobalamin, which can be awful for those with anemia as it overworks the body and heart to convert to usable B12. People with anemia already face challenges due to low oxygen levels in their blood. After taking B12 injections with cyanocobalamin, I struggled for three days due to a racing heart and shortness of breath! I will definitely buy again!
Read More
10
Effective treatment
4 people found this helpful
This medication saved me from terrible iron deficiency and second-degree anemia. After starting, my iron levels rose significantly, and I feel fantastic. I have gained strength, no longer experience dizziness, and my cravings for chalk and clay have disappeared. I highly recommend it!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 39 Researches
7.9
- All Researches
9.5
We explored the case of a 23-month-old boy suffering from severe pancytopenia linked to Imerslund-Gräsbeck syndrome, a rare condition caused by an inability to absorb vitamin B12. Upon diagnosis, the boy received vitamin B12 replacement therapy, which effectively addressed his symptoms and improved his health.
This case highlights the significance of early detection and treatment of IGS to avoid potential neurological damage. It's crucial to recognize this condition, even when neurological symptoms are absent, to provide timely care.
This case highlights the significance of early detection and treatment of IGS to avoid potential neurological damage. It's crucial to recognize this condition, even when neurological symptoms are absent, to provide timely care.
Read More
9.5
We focused on how oral vitamin B12 could help those with pernicious anemia, where absorption is usually impaired. Participants diagnosed with vitamin B12 deficiency due to this condition took a daily dose of 1000 μg of oral cyanocobalamin.
Over a year, an impressive 88.5% of them no longer showed deficiency after just one month, with significant improvements in vitamin B12 levels and related biological markers. Importantly, these benefits lasted throughout the study period.
Over a year, an impressive 88.5% of them no longer showed deficiency after just one month, with significant improvements in vitamin B12 levels and related biological markers. Importantly, these benefits lasted throughout the study period.
Read More
9.5
We observed a compelling case involving a 32-year-old pregnant woman who experienced severe anemia during her pregnancy. This specific type of anemia, known as sideroblastic anemia, is quite rare in expectant mothers. The patient had been feeling weak and had heart palpitations for two weeks when she came to the emergency room.
Testing revealed she had an alarming hemoglobin level of just 4.2 g/dl, indicating severe anemia, along with a notably low reticulocyte count. What made this case particularly interesting was her history of recurrent anemia, which occurred exclusively during her pregnancies.
Upon examining her bone marrow, doctors found numerous ring sideroblasts, which confirmed the diagnosis of sideroblastic anemia. Further investigation uncovered extremely low levels of pyridoxine, or vitamin B6, in her system. After administering vitamin B6 replacement therapy, her hemoglobin levels improved significantly without the need for blood transfusions, highlighting the vitamin’s role in managing this type of anemia during pregnancy.
Testing revealed she had an alarming hemoglobin level of just 4.2 g/dl, indicating severe anemia, along with a notably low reticulocyte count. What made this case particularly interesting was her history of recurrent anemia, which occurred exclusively during her pregnancies.
Upon examining her bone marrow, doctors found numerous ring sideroblasts, which confirmed the diagnosis of sideroblastic anemia. Further investigation uncovered extremely low levels of pyridoxine, or vitamin B6, in her system. After administering vitamin B6 replacement therapy, her hemoglobin levels improved significantly without the need for blood transfusions, highlighting the vitamin’s role in managing this type of anemia during pregnancy.
Read More
9.5
We observed that Vitamin B6 (VB6) plays a crucial role in preventing certain types of anemia, particularly in individuals undergoing treatment for Parkinson's disease. In this case, a 75-year-old man who was receiving levodopa/carbidopa intestinal gel therapy developed severe VB6 deficiency anemia. This condition is characterized by microcytic, hypochromic, and sideroblastic blood profiles, which can resemble myelodysplastic syndrome.
The effects of the levodopa/carbidopa treatment were significant because the metabolism of levodopa relies heavily on VB6. Furthermore, the medication carbidopa has an adverse effect—it binds to and deactivates VB6, worsening the deficiency. Fortunately, our findings highlight that the symptoms of VB6 deficiency anemia can be effectively resolved with simple oral supplementation of pyridoxal phosphate hydrate.
This case underlines the necessity of recognizing VB6 deficiency anemia as a potential cause of anemia in patients receiving levodopa/carbidopa, distinguishing it from more serious conditions like myelodysplastic syndrome. Awareness of this link can lead to better diagnosis and treatment of anemia in these patients, emphasizing the importance of monitoring Vitamin B6 levels during treatment.
The effects of the levodopa/carbidopa treatment were significant because the metabolism of levodopa relies heavily on VB6. Furthermore, the medication carbidopa has an adverse effect—it binds to and deactivates VB6, worsening the deficiency. Fortunately, our findings highlight that the symptoms of VB6 deficiency anemia can be effectively resolved with simple oral supplementation of pyridoxal phosphate hydrate.
This case underlines the necessity of recognizing VB6 deficiency anemia as a potential cause of anemia in patients receiving levodopa/carbidopa, distinguishing it from more serious conditions like myelodysplastic syndrome. Awareness of this link can lead to better diagnosis and treatment of anemia in these patients, emphasizing the importance of monitoring Vitamin B6 levels during treatment.
Read More
9.5
We observed the influence of nutrition education and iron-folic acid (IFA) supplementation on the levels of anemia among pregnant women in Butajira, Ethiopia. Through a quasi-experimental design over three months, we provided pregnant women with health education based on the Health Belief Model, alongside IFA supplements over a six-week period.
At the end of the study, we noticed a remarkable improvement. The proportion of anemia in women receiving the intervention dropped significantly from 27.8% to just 7.2%. Additionally, the knowledge about IFA supplementation improved notably in the intervention group compared to those who did not receive the same level of education, showing a clear connection between education, adherence to supplementation, and overall hemoglobin levels.
We found that participants who engaged in the educational interventions were more likely to adhere to their IFA supplement regimen—2.26 times more so than those who did not participate. This highlights the vital role that combining community-based education and supplementation can play in tackling anemia during pregnancy and improving maternal health outcomes effectively.
At the end of the study, we noticed a remarkable improvement. The proportion of anemia in women receiving the intervention dropped significantly from 27.8% to just 7.2%. Additionally, the knowledge about IFA supplementation improved notably in the intervention group compared to those who did not receive the same level of education, showing a clear connection between education, adherence to supplementation, and overall hemoglobin levels.
We found that participants who engaged in the educational interventions were more likely to adhere to their IFA supplement regimen—2.26 times more so than those who did not participate. This highlights the vital role that combining community-based education and supplementation can play in tackling anemia during pregnancy and improving maternal health outcomes effectively.
Read More
User Reviews
USERS' SCORE
Good
Based on 20 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Calmer emotions
18 people found this helpful
B12 is essential for maintaining good iron stores, and its active form is well absorbed. I noticed that low B12 can lead to irritability and aggression, so I supplement with B vitamins, especially B12 and magnesium glycinate, which helps me feel calmer and reduces anxiety. I find that B vitamins are a necessity for me. Although this product includes inactive forms of B6 and folic acid, its effectiveness for hair health is excellent. The tablets taste unpleasant but dissolve quickly.
Read More
9
Wonderful effect
14 people found this helpful
Amazing! I have pernicious anemia and these tablets are wonderful for me. I love that they do not contain cyanocobalamin, which can be awful for those with anemia as it overworks the body and heart to convert to usable B12. People with anemia already face challenges due to low oxygen levels in their blood. After taking B12 injections with cyanocobalamin, I struggled for three days due to a racing heart and shortness of breath! I will definitely buy again!
Read More
10
Effective treatment
4 people found this helpful
This medication saved me from terrible iron deficiency and second-degree anemia. After starting, my iron levels rose significantly, and I feel fantastic. I have gained strength, no longer experience dizziness, and my cravings for chalk and clay have disappeared. I highly recommend it!
Read More
9
For vegetarians
3 people found this helpful
I highly recommend B12 for vegetarians, as it’s vital for blood cell formation and preventing anemia. The package contains 90 tablets, and it's important to dissolve one in your mouth before swallowing. I find the taste quite pleasant.
Read More
9
Better hair and skin
1 people found this helpful
We used it as part of a treatment for anemia, which positively affected my hair and skin health, and it improved my sleep. I definitely recommend this!
Read More
Frequently Asked Questions
8
We explored a case involving a 51-year-old Ugandan man who experienced recurring lower limb weakness and was ultimately diagnosed with pernicious anemia. His condition stemmed from vitamin B12 deficiency, confirmed by blood tests showing macrocytic anemia and low cobalamin levels.
With treatment using methylcobalamin injections, he showed significant improvement. This case emphasizes the need for heightened awareness of vitamin B12 deficiency in diagnosing anemia, especially in areas with limited health resources.
With treatment using methylcobalamin injections, he showed significant improvement. This case emphasizes the need for heightened awareness of vitamin B12 deficiency in diagnosing anemia, especially in areas with limited health resources.
7
We sought to understand how effective vitamin B12 is in treating anemia in children. Our focus was on comparing two different methods of supplementation: parenteral (injections) and oral (pills). While previous studies in adults suggested both methods might have similar benefits, we found limited data for children, prompting our thorough investigation.
Our literature search pulled from multiple reputable databases for randomized controlled trials that specifically looked at vitamin B12 treatments in children with deficiency anemia. Of the thousands of studies reviewed, only one qualified for our analysis. In this study, children received an initial injection of vitamin B12 before being assigned to either the parenteral or oral treatment group.
We observed notable differences in the outcomes after three months. The children who received the parenteral treatment showed significantly higher vitamin B12 levels and better improvements in hemoglobin, indicating that this method may be more effective. However, we should note that the quality of the study was deemed high risk for bias, and there was no safety data reported, making it challenging to draw strong conclusions.
Overall, while the findings hint at a greater effectiveness of parenteral supplementation, the lack of robust evidence calls for caution in interpreting these results. Further high-quality research is necessary before definitive recommendations can be made.
Our literature search pulled from multiple reputable databases for randomized controlled trials that specifically looked at vitamin B12 treatments in children with deficiency anemia. Of the thousands of studies reviewed, only one qualified for our analysis. In this study, children received an initial injection of vitamin B12 before being assigned to either the parenteral or oral treatment group.
We observed notable differences in the outcomes after three months. The children who received the parenteral treatment showed significantly higher vitamin B12 levels and better improvements in hemoglobin, indicating that this method may be more effective. However, we should note that the quality of the study was deemed high risk for bias, and there was no safety data reported, making it challenging to draw strong conclusions.
Overall, while the findings hint at a greater effectiveness of parenteral supplementation, the lack of robust evidence calls for caution in interpreting these results. Further high-quality research is necessary before definitive recommendations can be made.
9.5
We investigated how vitamin B12 treatment plays a role in addressing anemia in a young adolescent with complex health issues, including severe anemia, joint problems, and neurological symptoms. This individual presented with a deficiency in vitamin B12, alongside other autoimmune conditions, leading to a diagnosis of subacute combined degeneration of the spinal cord.
The patient's treatment regimen included high-dose intravenous methylprednisolone, immunoglobulin therapy, oral naproxen, and vitamin B12 supplementation, among others. We observed that the introduction of vitamin B12 into her treatment plan contributed to combating her anemia effectively. The combination of therapies, especially with vitamin B12, significantly improved her overall health and restored her quality of life.
Our findings highlight the importance of early diagnosis and prompt treatment in patients with complex autoimmune issues. Specifically, vitamin B12 emerges as a critical component in managing anemia related to such conditions. While the study is anecdotal, it reinforces the idea that vitamin B12 can be beneficial in improving anemia outcomes in similarly affected patients.
The patient's treatment regimen included high-dose intravenous methylprednisolone, immunoglobulin therapy, oral naproxen, and vitamin B12 supplementation, among others. We observed that the introduction of vitamin B12 into her treatment plan contributed to combating her anemia effectively. The combination of therapies, especially with vitamin B12, significantly improved her overall health and restored her quality of life.
Our findings highlight the importance of early diagnosis and prompt treatment in patients with complex autoimmune issues. Specifically, vitamin B12 emerges as a critical component in managing anemia related to such conditions. While the study is anecdotal, it reinforces the idea that vitamin B12 can be beneficial in improving anemia outcomes in similarly affected patients.
8
We explored the fascinating case of megaloblastic anemia (MA) in children, a rare but significant health issue often tied to deficiencies in folic acid and vitamin B12. Our research was conducted over 42 years at the Hedi Chaker University Hospital, where we carefully examined cases of MA diagnosed through myelograms revealing megaloblastosis in children under 16.
Throughout our study, we observed various attributes of this condition, highlighting how folic acid plays a crucial role. The clinical presentations often included severe anemia, notably with a median hemoglobin level of just 5.6 g/dL. Some children also experienced neurological issues and developmental delays, indicating the multifaceted impacts of these vitamin deficiencies.
While we did not find a specific isolated effect of folate on anemia due to overlapping treatment methods, our findings reinforced the need for comprehensive dietary management. Overall, several patients showed improvement with treatment, though a few experienced lasting neurological consequences. This underscores the importance of timely diagnosis and intervention to mitigate long-term effects.
Ultimately, we learned that while folate is essential in the context of anemia, its direct, isolated effect remains challenging to determine. This study serves as a reminder of the complex interplay between nutrition and health in childhood.
Throughout our study, we observed various attributes of this condition, highlighting how folic acid plays a crucial role. The clinical presentations often included severe anemia, notably with a median hemoglobin level of just 5.6 g/dL. Some children also experienced neurological issues and developmental delays, indicating the multifaceted impacts of these vitamin deficiencies.
While we did not find a specific isolated effect of folate on anemia due to overlapping treatment methods, our findings reinforced the need for comprehensive dietary management. Overall, several patients showed improvement with treatment, though a few experienced lasting neurological consequences. This underscores the importance of timely diagnosis and intervention to mitigate long-term effects.
Ultimately, we learned that while folate is essential in the context of anemia, its direct, isolated effect remains challenging to determine. This study serves as a reminder of the complex interplay between nutrition and health in childhood.
9.5
We focused on how oral vitamin B12 could help those with pernicious anemia, where absorption is usually impaired. Participants diagnosed with vitamin B12 deficiency due to this condition took a daily dose of 1000 μg of oral cyanocobalamin.
Over a year, an impressive 88.5% of them no longer showed deficiency after just one month, with significant improvements in vitamin B12 levels and related biological markers. Importantly, these benefits lasted throughout the study period.
Over a year, an impressive 88.5% of them no longer showed deficiency after just one month, with significant improvements in vitamin B12 levels and related biological markers. Importantly, these benefits lasted throughout the study period.
We conducted a study to explore how effective different vitamin B12 supplements are at increasing levels of this crucial vitamin in people with a deficiency. This clinical trial involved healthy adults who were found to have low B12 levels.
Our research spanned across three centers in Pakistan, where participants received either a new formulation of Sucrosomial vitamin B12 or conventional B12 supplements. They took a daily dose for seven days, and we measured their serum B12 levels at various points before and after the treatment.
What we found was quite significant: the Sucrosomial vitamin B12 was notably better at elevating and maintaining higher B12 levels in the bloodstream compared to traditional options. This is important because low vitamin B12 can lead to serious health issues, like megaloblastic anemia and neurological problems.
Overall, this innovative supplement could offer a valuable solution for individuals with B12 deficiency, especially those who may have absorption issues. Our findings support the potential of Sucrosomial vitamin B12 in enhancing health through improved nutrient bioavailability.
Our research spanned across three centers in Pakistan, where participants received either a new formulation of Sucrosomial vitamin B12 or conventional B12 supplements. They took a daily dose for seven days, and we measured their serum B12 levels at various points before and after the treatment.
What we found was quite significant: the Sucrosomial vitamin B12 was notably better at elevating and maintaining higher B12 levels in the bloodstream compared to traditional options. This is important because low vitamin B12 can lead to serious health issues, like megaloblastic anemia and neurological problems.
Overall, this innovative supplement could offer a valuable solution for individuals with B12 deficiency, especially those who may have absorption issues. Our findings support the potential of Sucrosomial vitamin B12 in enhancing health through improved nutrient bioavailability.
References
- Mesgarankarimi A, Rezapour M, Tabrizi N. A long-standing undiagnosed case of vitamin B12 deficiency: a case report. J Med Case Rep. 2025;19:151. doi:10.1186/s13256-025-05149-7
- Upadhyay RP, Chowdhury R, Mundra S, Taneja S, Jacob M, et al. Comparative effectiveness of daily therapeutic supplementation with multiple micronutrients and iron-folic acid versus iron-folic acid alone in children with mild-to-moderate anaemia in rural India: an open-label, randomised controlled trial. Lancet Glob Health. 2025;13:e497. doi:10.1016/S2214-109X(24)00559-X
- Mswelo VE, David MM, Banturaki A, Munyambalu DK, Hassan HA, et al. Rural health challenges in Western Uganda: pernicious anemia masquerading as recurrent lower limb weakness-a case report. J Med Case Rep. 2025;19:60. doi:10.1186/s13256-025-05095-4
- Hirakata K, Ishii Y, Yoshida T, Tanaka F, Nakae Y. [A case of diagnosed pernicious anemia and subacute combined degeneration of the spinal cord with abnormally elevated serum vitamin B12]. Rinsho Shinkeigaku. 2025;65:120. doi:10.5692/clinicalneurol.cn-002023
- Zhang D, Liu S, Xi B, Zhu Y, Chen Y, et al. Imerslund-Gräsbeck syndrome in a child with a novel compound heterozygous mutations in the AMN gene: a case report. Ital J Pediatr. 2024;50:191. doi:10.1186/s13052-024-01757-z
- Di Sario F, Piloni F, Gasparini F, Serpetti E, Bruschi B, et al. Severe pancytopenia at the presentation of Imerslund-Gräsbeck syndrome in a 23-month-old Italian boy. Ital J Pediatr. 2024;50:186. doi:10.1186/s13052-024-01759-x
- Shen M, Luo X, Wu C, Wang J, Wang Z, et al. Pernicious anemia is a common cause of cobalamin deficiency-caused megaloblastic anemia in Hainan, China. Hematology. 2024;29:2399375. doi:10.1080/16078454.2024.2399375
- Iqbal N, Meghani MA, Khalid W, Ansari AH, Ansari MUH, et al. Transcobalamin deficiency - a rare genetic defect in transportation of cobalamin; case report. Ann Hematol. 2024;103:3243. doi:10.1007/s00277-024-05878-7
- Song JH, Park SH, Cho M, Kim YM, Hyung WJ, et al. Proximal Gastrectomy Is Associated with Lower Incidence of Anemia and Vitamin B12 Deficiency Compared to Total Gastrectomy in Patients with Upper Gastric Cancer. Cancer Res Treat. 2025;57:174. doi:10.4143/crt.2024.319
- Lacombe V, Vinatier E, Roquin G, Copin MC, Delattre E, et al. Oral vitamin B12 supplementation in pernicious anemia: a prospective cohort study. Am J Clin Nutr. 2024;120:217. doi:10.1016/j.ajcnut.2024.05.019
- Chakrabarti S, Ajjampur SSR, Waddington HS, Kishore A, Nguyen PH, et al. Deworming and micronutrient status by community open defecation prevalence: An observational study using nationally representative data from India, 2016-2018. PLoS Med. 2024;21:e1004402. doi:10.1371/journal.pmed.1004402
- Sawada Y, Sakamoto K, Tsukamura A, Sawai C. Vitamin B12 deficiency-induced megaloblastic anemia in a pediatric patient with autism spectrum disorder with a chronically unbalanced diet. Int J Hematol. 2024;119:613. doi:10.1007/s12185-024-03759-3
- Cai J, Liu T, Huang Y, Chen H, Yu M, et al. A novel and apparent missense variant associated with congenital sideroblastic anemia. Front Pediatr. 2024;12:1411676. doi:10.3389/fped.2024.1411676
- Ducamp S, Sendamarai AK, Campagna DR, Chin DWL, Fujiwara Y, et al. Murine models of erythroid 5ALA synthesis disorders and their conditional synthetic lethal dependency on pyridoxine. Blood. 2024;144:1418. doi:10.1182/blood.2023023078
- Shao Y, He L, Ding S, Fu R. Luspatercept for the treatment of congenital sideroblastic anemia: Two case reports. Curr Res Transl Med. 2024;72:103438. doi:10.1016/j.retram.2024.103438
- Mohamed S, Ibrahim F, Alasafar MN, Alshurafa A, Akiki S, et al. Recurrent sideroblastic anemia during pregnancy. Clin Case Rep. 2023;11:e6814. doi:10.1002/ccr3.6814
- Yasuda H, Hatano T, Honda T, Tsutsui M, Hattori N, et al. Vitamin B6 Deficiency Anemia Attributed to Levodopa/Carbidopa Intestinal Gel Therapy for Parkinson's Disease: A Diagnostic Pitfall for Myelodysplastic Syndrome with Ring Sideroblasts. Intern Med. 2022;61:3719. doi:10.2169/internalmedicine.9577-22
- Abu-Zeinah G, DeSancho MT. Understanding Sideroblastic Anemia: An Overview of Genetics, Epidemiology, Pathophysiology and Current Therapeutic Options. J Blood Med. 2020;11:305. doi:10.2147/JBM.S232644
- Merga RT, Birhane M, Dhinsa M, Muleta B, Jemal J, et al. Determinants of compliance with iron-folic acid supplementation among pregnant mothers in Bule Hora district, Southern Ethiopia: unmatched case-control study. BMC Public Health. 2025;25:832. doi:10.1186/s12889-025-22005-x
- Weeks CJ, Mian M, Stokes M, Gold M, Shah A, et al. The Role of Ferritin and Folate in Determining Stem Cell Collection for Autologous Stem Cell Transplant in Multiple Myeloma. Hematol Rep. 2025;17. doi:10.3390/hematolrep17010005
- Taye M, Mohammed T, Taye W, Glagn M, Yihune M. Compliance with iron-folate supplementation among pregnant women in Southern Ethiopia: a multi-center cross-sectional study. Reprod Health. 2025;22:22. doi:10.1186/s12978-025-01944-z
- Anato A, Reshid M. Effect of nutrition education and iron-folic acid supplementation on anemia among pregnant women in Ethiopia: a quasi-experimental study. Sci Rep. 2025;15:3556. doi:10.1038/s41598-025-87957-x
- Kant SB, Bashir R, Khan B, Shabbir NA, Nizami AA, et al. A Cross-Sectional Study of the Maternal Health Factors: The Interplay Between Breastfeeding Patterns, Gut Microbiota, Anemia, and Cardiovascular Risk in Lactating Mothers. Cureus. 2024;16:e76316. doi:10.7759/cureus.76316
- Belhaj R, Maaloul I, Kolsi R, Rekik T, Chabchoub I, et al. Study of clinical manifestations and etiologies of megaloblastic anemia in children. Transfus Clin Biol. 2025. doi:10.1016/j.tracli.2025.01.006
- Moreira AP, Vasconcelos M, Costa E Silva T, Relvas C, Espírito Santo J. An Unusual Case of Hemolytic Anemia: A Case Report. Cureus. 2024;16:e75676. doi:10.7759/cureus.75676
- Kataria S, Kataria S, Chougule D, Bharti B, Rastogi A. Evaluating the Impact of an Iron Supplementation Program for Combating Anemia in School-Age and Adolescent Females by a Grassroots Organization in India. Cureus. 2024;16:e75608. doi:10.7759/cureus.75608
- Bolka A, Bosha T, Gebremedhin S. Effect of School-Based Weekly Iron and Folic Acid Supplementation Program on the Serum Folate Status of Adolescent Girls in Sidama Region, Southern Ethiopia: Comparative Cross-Sectional Study. Food Nutr Bull. 2025. doi:10.1177/03795721241304475
- Chillo SL, Woldesemayat EM, Dangisso MH. Intermittent versus daily oral iron folic acid supplementation and pregnancy outcome in low- and middle-income countries: a systematic review and meta-analysis of experimental studies. Reprod Health. 2025;22:2. doi:10.1186/s12978-024-01917-8
- Kaneko M, Masuda Y, Ishikawa K, Shikata H. Coexistence of Cold Agglutinin and Cryoglobulin in a Patient With Severe Anemia Following COVID-19 Infection. Cureus. 2024;16:e75257. doi:10.7759/cureus.75257
- Contreras R, Méndez GP, Mujica J, Padilla C, Selamé ME, et al. [Paroxysmal Nocturnal Hemoglobinuria: A Rare but Treatable Cause of Acute Kidney Injury. Case Report]. Rev Med Chil. 2024;152:627. doi:10.4067/s0034-98872024000500627
- Singh G, Ranjitha R, Baskaran P, Goel AD, Gupta MK, et al. Family-centered Health Education Intervention for Improving Iron-folic Acid Adherence and Anemia Reduction among Antenatal Mothers in Rural Jodhpur: A Quasi-experimental Study. Indian J Public Health. 2024;68:495. doi:10.4103/ijph.ijph_844_23
- Zhang C, Cha R, Long K, Liu Y, Dong Y, et al. Functionalized Iron Oxide Nanoparticles for Both Dual-Modal Imaging and Erythropoiesis. ACS Appl Mater Interfaces. 2024;16:68905. doi:10.1021/acsami.4c15206
- Sachdeva M, Purohit A, Malik M, Jain L, Pradhan P, et al. Comparison of Efficacy and Safety of Parenteral vs Oral Route of Vitamin B12 Supplementation for the Treatment of Vitamin B12 Deficiency Anemia in Children: A Systematic Review. Nutr Rev. 2025. doi:10.1093/nutrit/nuae227
- Obeid R, Geisel J, Pietrzik K, Andres E. A Framework to Guide Defining an Upper Threshold of Crystalline Vitamin B12 in Foods and Food Supplements. Curr Nutr Rep. 2025;14:32. doi:10.1007/s13668-025-00622-7
- Goncalves H, De Oliveira Simões F, Sá R, Fraga Campos B, Domingues RM, et al. Severe Symptomatic Anemia as a Rare Initial Manifestation of Type 3 Polyglandular Autoimmune Syndrome: A Case Report. Cureus. 2024;16:e75800. doi:10.7759/cureus.75800
- Lang C, Huang P, Gao J, Chen Y, He Z. Co-existence of autoimmune polyglandular syndrome type 3b and undifferentiated connective tissue disease with subacute combined degeneration of spinal cord in children: a case report and literature review. BMC Pediatr. 2024;24:817. doi:10.1186/s12887-024-05262-4
- Tavares Pereira J, Barbosa Barroso J, Azevedo A, Ribeiro A, Tonel C. Pseudo-Thrombotic Microangiopathy Secondary to Vitamin B12 Deficiency. Cureus. 2024;16:e73620. doi:10.7759/cureus.73620
- Jamil M, Nasser Z, Jamil D, Sheqwara JZ. Unmasking Vitamin B12 Deficiency Misdiagnosed as Myelodysplastic Syndrome. Case Rep Hematol. 2024;2024:3258227. doi:10.1155/2024/3258227
- Memon NM, Conti G, Brilli E, Tarantino G, Chaudhry MNA, et al. Comparative bioavailability study of supplemental oral Sucrosomial vs. oral conventional vitamin B12 in enhancing circulatory B12 levels in healthy deficient adults: a multicentre, double-blind randomized clinical trial. Front Nutr. 2024;11:1493593. doi:10.3389/fnut.2024.1493593
