We conducted a study to examine how coenzyme Q10, in its reduced form known as ubiquinol, might affect constipation in individuals dealing with daily abdominal discomfort. Using a robust, double-blind, randomized control design, we enlisted forty-one patients who experienced either constipation or diarrhea. Participants were split evenly into two groups, with one receiving 150 mg of ubiquinol each day for twelve weeks, while the other group received a placebo.
Over the course of the study, we had participants keep a daily diary to monitor their defecation frequency and the consistency of their stools, following the Bristol Stool Form Scale. After twelve weeks, we noticed some interesting changes. The ubiquinol group reported a slight decrease in defecation frequency, averaging -0.1 times a day, while the placebo group saw an increase of +0.3 times a day. However, there was no significant change in stool form for the ubiquinol group, while the placebo group’s scores improved.
On the brighter side, we also found that the ubiquinol group experienced a notable improvement in their overall health perception, reflected in their quality of life scores. In contrast, there were no significant changes in the placebo group’s scores. Overall, our findings suggest that ubiquinol may modify bowel habits and enhance the quality of life for patients suffering from abdominal distress, despite the small drop in defecation frequency among those taking it.
Read More
9.5
Coenzyme Q10 aids gut health
Unusual occurrence of intestinal pseudo obstruction in a patient with maternally inherited diabetes and deafness (MIDD) and favorable outcome with coenzyme Q10.
We observed a fascinating case involving a patient with maternally inherited diabetes and deafness (MIDD) who experienced chronic intestinal pseudo obstruction. This condition, while not commonly reported in MIDD patients, illustrates the broader impact of the condition on various bodily systems.
Interestingly, despite most gastrointestinal symptoms like constipation and diarrhea being more prevalent, the introduction of Coenzyme Q10 as a treatment option led to a resolution of the pseudo obstruction. This finding gives us promising insights into how Coenzyme Q10 can aid in gastrointestinal health, particularly for patients facing complex mitochondrial disorders.
Although the report focuses on intestinal pseudo obstruction rather than constipation explicitly, the positive outcome from Coenzyme Q10 suggests it may play a supportive role in managing related gastrointestinal symptoms. By further exploring this connection, we can better understand the potential benefits of Coenzyme Q10 in similar clinical settings.
Read More
Most Useful Reviews
1
Aging effects noted
25 people found this helpful
Initially, I felt full of energy, but then I realised it caused constipation. The effects felt less dramatic over time. While I continue taking it for its anti-aging benefits, I advise those with constipation to be cautious, as it can lead to bowel issues.
Read More
9
Restores microbiome
These probiotics are of excellent quality. They significantly help with constipation and are essential for gut health. The compact packaging contains powdered probiotics that noticeably improve digestion after just a week of use.
Read More
9
Relieves constipation
Artichokes are a superb source of fibre, promoting a healthy digestive system by supporting friendly gut bacteria and reducing the risk of constipation and colon cancers. They contain inulin, which acts as a prebiotic.
Unusual occurrence of intestinal pseudo obstruction in a patient with maternally inherited diabetes and deafness (MIDD) and favorable outcome with coenzyme Q10.
We observed a fascinating case involving a patient with maternally inherited diabetes and deafness (MIDD) who experienced chronic intestinal pseudo obstruction. This condition, while not commonly reported in MIDD patients, illustrates the broader impact of the condition on various bodily systems.
Interestingly, despite most gastrointestinal symptoms like constipation and diarrhea being more prevalent, the introduction of Coenzyme Q10 as a treatment option led to a resolution of the pseudo obstruction. This finding gives us promising insights into how Coenzyme Q10 can aid in gastrointestinal health, particularly for patients facing complex mitochondrial disorders.
Although the report focuses on intestinal pseudo obstruction rather than constipation explicitly, the positive outcome from Coenzyme Q10 suggests it may play a supportive role in managing related gastrointestinal symptoms. By further exploring this connection, we can better understand the potential benefits of Coenzyme Q10 in similar clinical settings.
Read More
4
Ubiquinol shows mixed effects
Effect of Ubiquinol Intake on Defecation Frequency and Stool Form: A Prospective, Double-Blinded, Randomized Control Study.
We conducted a study to examine how coenzyme Q10, in its reduced form known as ubiquinol, might affect constipation in individuals dealing with daily abdominal discomfort. Using a robust, double-blind, randomized control design, we enlisted forty-one patients who experienced either constipation or diarrhea. Participants were split evenly into two groups, with one receiving 150 mg of ubiquinol each day for twelve weeks, while the other group received a placebo.
Over the course of the study, we had participants keep a daily diary to monitor their defecation frequency and the consistency of their stools, following the Bristol Stool Form Scale. After twelve weeks, we noticed some interesting changes. The ubiquinol group reported a slight decrease in defecation frequency, averaging -0.1 times a day, while the placebo group saw an increase of +0.3 times a day. However, there was no significant change in stool form for the ubiquinol group, while the placebo group’s scores improved.
On the brighter side, we also found that the ubiquinol group experienced a notable improvement in their overall health perception, reflected in their quality of life scores. In contrast, there were no significant changes in the placebo group’s scores. Overall, our findings suggest that ubiquinol may modify bowel habits and enhance the quality of life for patients suffering from abdominal distress, despite the small drop in defecation frequency among those taking it.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 6 Reviews
6.4
All Reviews
Positive Reviews
Negative Reviews
1
Aging effects noted
25 people found this helpful
Initially, I felt full of energy, but then I realised it caused constipation. The effects felt less dramatic over time. While I continue taking it for its anti-aging benefits, I advise those with constipation to be cautious, as it can lead to bowel issues.
Read More
9
Restores microbiome
These probiotics are of excellent quality. They significantly help with constipation and are essential for gut health. The compact packaging contains powdered probiotics that noticeably improve digestion after just a week of use.
Read More
9
Relieves constipation
Artichokes are a superb source of fibre, promoting a healthy digestive system by supporting friendly gut bacteria and reducing the risk of constipation and colon cancers. They contain inulin, which acts as a prebiotic.
Read More
1
Causes constipation
I chose this for its absorption rate, but unfortunately, it causes constipation, which is disappointing.
Read More
2
Constipation issues
5 people found this helpful
I had high hopes for Omega 3, but it caused constipation. I have to take laxatives to counteract this side effect, which is disappointing. However, some ingredients do provide relief for constipation in other uses.
Constipation is a common condition characterized by infrequent bowel movements or difficulty passing stools. It is typically defined as having fewer than three bowel movements per week, leading to hard, dry stools that are painful or difficult to expel. This condition can be caused by a variety of factors, including diet, dehydration, lack of physical activity, and certain medications. Stress and lifestyle changes can also contribute, making it essential for individuals to identify the root causes of their constipation for effective relief.
To alleviate constipation, it’s recommended to increase fiber intake by consuming more fruits, vegetables, whole grains, and legumes, as well as ensuring adequate hydration throughout the day. Regular exercise can also promote healthy bowel function. If over-the-counter solutions such as fiber supplements or laxatives aren't effective, it's advisable to consult a healthcare provider, as chronic constipation can lead to complications and indicate underlying health issues. Keeping a consistent eating and bathroom schedule can also help regulate bowel movements.
Coenzyme Q10, often abbreviated as CoQ10, is a naturally occurring antioxidant that is found in the cells of the body. It plays a crucial role in the production of energy within mitochondria, which are the powerhouses of our cells. CoQ10 is important for maintaining cellular energy levels and overall health, as it assists in the conversion of food into energy. Additionally, it helps protect cells from oxidative damage, which is linked to various conditions such as heart disease and aging.
As a dietary supplement, CoQ10 is popular for its potential benefits, including promoting heart health, improving energy levels, and supporting cognitive function. It's particularly beneficial for individuals who are taking statin medications, as these drugs can lower natural CoQ10 levels in the body. While more research is needed to determine its efficacy fully, many users have reported positive experiences. If you’re considering adding CoQ10 to your supplement routine, it’s best to consult with a healthcare professional to determine the appropriate dosage and ensure it fits your health needs.
Based on user reviews, the time it takes to see results for constipation when taking supplements can vary significantly. Some users report noticeable improvements in digestion and constipation relief within just one week of use, particularly when taking high-quality probiotics (Read Review). However, not all users have had a positive experience; some have reported constipation as a side effect of other supplements, such as Omega 3, and have had to resort to laxatives to alleviate the issue (Read Review).
Overall, while some users have seen results in under a week, others experienced adverse effects that complicated their situation. It's important to consider individual responses to different supplements and to consult with a healthcare professional if constipation persists or worsens.
Research indicates that ubiquinol, a form of coenzyme Q10, may have some impact on constipation management, although the findings are mixed. A study focused on individuals with abdominal discomfort noted that participants taking 150 mg of ubiquinol daily for twelve weeks reported a slight decrease in defecation frequency compared to the placebo group, which showed an increase in bowel movements. However, this change was not statistically significant, and there were no notable improvements in stool consistency among those taking ubiquinol. The study did highlight that participants in the ubiquinol group experienced a better overall health perception, suggesting possible benefits in quality of life despite the lack of marked improvement in constipation symptoms [1].
Additionally, another report explored the treatment of chronic intestinal pseudo-obstruction in a patient with a mitochondrial disorder using coenzyme Q10. While this case did not explicitly address constipation, the successful resolution of gastrointestinal symptoms following coenzyme Q10 treatment points to its potential relevance in broader gastrointestinal health [2]. Overall, although there is some emerging evidence supporting the role of ubiquinol and coenzyme Q10 in managing digestive health, further investigations are necessary to conclusively establish their efficacy in treating constipation.
Based on user reviews, experiences with symptom improvement can vary significantly. Some users have reported substantial benefits from taking probiotics, with one user stating they experienced noticeable digestive improvements, including relief from constipation, after just a week of use (Read Review). Additionally, products containing fiber-rich ingredients, like artichokes, have been noted for their positive impact on gut health, potentially reducing constipation and promoting a healthy digestive system (Read Review).
However, not all experiences have been positive. Some users have encountered constipation as a side effect from certain supplements, such as Omega 3 and others with high absorption rates, leading them to rely on laxatives to manage their symptoms (Read Review, Read Review). This highlights the importance of individual responses to supplements, suggesting that while some may find relief, others might experience unintended gastrointestinal issues. As always, it's advisable to consult with a healthcare professional if symptoms persist or worsen.
According to user reviews, experiences with combining supplements for handling constipation display a mixed bag of results. For instance, while some users have found success with probiotics, reporting significant improvements in digestion after just a week (Read Review) and highlighting their positive impact on gut health, others have faced challenges. One user noted that taking Omega 3 led to constipation, warranting the use of laxatives to alleviate the issue, which illustrates the possibility of adverse side effects when introducing new supplements into one's regimen (Read Review).
Furthermore, certain supplements with high absorption rates, like another user's choice, were reported to cause constipation as well, complicating their experience (Read Review). Users have advised exercising caution, particularly with supplements that may lead to bowel issues, emphasizing the importance of individual responses when mixing different supplements (Read Review). Overall, these insights suggest that while some formulations can enhance digestive health, others could lead to unintended consequences.
Based on user reviews, it appears that Coenzyme Q10 (CoQ10) may not be the best choice for those looking to treat constipation. Several users have reported experiencing constipation as a side effect after taking CoQ10, suggesting that the supplement may not suit everyone. One reviewer noted that although they initially felt energized, they later realized it contributed to their bowel issues and advised caution for those already suffering from constipation Read Review. Another user shared a similar fate, expressing disappointment as they expected health benefits but were met with constipation instead Read Review.
While there were no specific doses mentioned in relation to managing constipation in the reviews, the overall sentiment leans towards the need for caution when considering CoQ10 for gastrointestinal issues. Users recommended exploring other options or supporting supplements if constipation arises, indicating thatCoQ10's benefits might be overshadowed by this uncomfortable side effect. As with any supplement, it is advisable to consult a healthcare professional to determine the right approach for individual dietary needs and health concerns.
9
Restores microbiome
These probiotics are of excellent quality. They significantly help with constipation and are essential for gut health. The compact packaging contains powdered probiotics that noticeably improve digestion after just a week of use.
2
Constipation issues
5 people found this helpful
I had high hopes for Omega 3, but it caused constipation. I have to take laxatives to counteract this side effect, which is disappointing. However, some ingredients do provide relief for constipation in other uses.
9
Relieves constipation
Artichokes are a superb source of fibre, promoting a healthy digestive system by supporting friendly gut bacteria and reducing the risk of constipation and colon cancers. They contain inulin, which acts as a prebiotic.
1
Causes constipation
I chose this for its absorption rate, but unfortunately, it causes constipation, which is disappointing.
1
Aging effects noted
25 people found this helpful
Initially, I felt full of energy, but then I realised it caused constipation. The effects felt less dramatic over time. While I continue taking it for its anti-aging benefits, I advise those with constipation to be cautious, as it can lead to bowel issues.
4
Ubiquinol shows mixed effects
Effect of Ubiquinol Intake on Defecation Frequency and Stool Form: A Prospective, Double-Blinded, Randomized Control Study.
We conducted a study to examine how coenzyme Q10, in its reduced form known as ubiquinol, might affect constipation in individuals dealing with daily abdominal discomfort. Using a robust, double-blind, randomized control design, we enlisted forty-one patients who experienced either constipation or diarrhea. Participants were split evenly into two groups, with one receiving 150 mg of ubiquinol each day for twelve weeks, while the other group received a placebo.
Over the course of the study, we had participants keep a daily diary to monitor their defecation frequency and the consistency of their stools, following the Bristol Stool Form Scale. After twelve weeks, we noticed some interesting changes. The ubiquinol group reported a slight decrease in defecation frequency, averaging -0.1 times a day, while the placebo group saw an increase of +0.3 times a day. However, there was no significant change in stool form for the ubiquinol group, while the placebo group’s scores improved.
On the brighter side, we also found that the ubiquinol group experienced a notable improvement in their overall health perception, reflected in their quality of life scores. In contrast, there were no significant changes in the placebo group’s scores. Overall, our findings suggest that ubiquinol may modify bowel habits and enhance the quality of life for patients suffering from abdominal distress, despite the small drop in defecation frequency among those taking it.
9.5
Coenzyme Q10 aids gut health
Unusual occurrence of intestinal pseudo obstruction in a patient with maternally inherited diabetes and deafness (MIDD) and favorable outcome with coenzyme Q10.
We observed a fascinating case involving a patient with maternally inherited diabetes and deafness (MIDD) who experienced chronic intestinal pseudo obstruction. This condition, while not commonly reported in MIDD patients, illustrates the broader impact of the condition on various bodily systems.
Interestingly, despite most gastrointestinal symptoms like constipation and diarrhea being more prevalent, the introduction of Coenzyme Q10 as a treatment option led to a resolution of the pseudo obstruction. This finding gives us promising insights into how Coenzyme Q10 can aid in gastrointestinal health, particularly for patients facing complex mitochondrial disorders.
Although the report focuses on intestinal pseudo obstruction rather than constipation explicitly, the positive outcome from Coenzyme Q10 suggests it may play a supportive role in managing related gastrointestinal symptoms. By further exploring this connection, we can better understand the potential benefits of Coenzyme Q10 in similar clinical settings.
References
Suzuki S, Gotoda T, Kusano C, Ikehara H, Miyakoshi Y, et al. Effect of Ubiquinol Intake on Defecation Frequency and Stool Form: A Prospective, Double-Blinded, Randomized Control Study. J Med Food. 2019;22:81. 10.1089/jmf.2018.4233