Last update
5/30/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.8
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.9
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Coenzyme Q10 (Ubiquinone)
100 mg
†
Black Pepper Ext. (Piper nigrum) (fruit) (standardized to contain 95% Piperine) (BioPerine®)
5 mg
†
Top Medical Research Studies
4
We conducted a study to examine how coenzyme Q10, in its reduced form known as ubiquinol, might affect constipation in individuals dealing with daily abdominal discomfort. Using a robust, double-blind, randomized control design, we enlisted forty-one patients who experienced either constipation or diarrhea. Participants were split evenly into two groups, with one receiving 150 mg of ubiquinol each day for twelve weeks, while the other group received a placebo.
Over the course of the study, we had participants keep a daily diary to monitor their defecation frequency and the consistency of their stools, following the Bristol Stool Form Scale. After twelve weeks, we noticed some interesting changes. The ubiquinol group reported a slight decrease in defecation frequency, averaging -0.1 times a day, while the placebo group saw an increase of +0.3 times a day. However, there was no significant change in stool form for the ubiquinol group, while the placebo group’s scores improved.
On the brighter side, we also found that the ubiquinol group experienced a notable improvement in their overall health perception, reflected in their quality of life scores. In contrast, there were no significant changes in the placebo group’s scores. Overall, our findings suggest that ubiquinol may modify bowel habits and enhance the quality of life for patients suffering from abdominal distress, despite the small drop in defecation frequency among those taking it.
Over the course of the study, we had participants keep a daily diary to monitor their defecation frequency and the consistency of their stools, following the Bristol Stool Form Scale. After twelve weeks, we noticed some interesting changes. The ubiquinol group reported a slight decrease in defecation frequency, averaging -0.1 times a day, while the placebo group saw an increase of +0.3 times a day. However, there was no significant change in stool form for the ubiquinol group, while the placebo group’s scores improved.
On the brighter side, we also found that the ubiquinol group experienced a notable improvement in their overall health perception, reflected in their quality of life scores. In contrast, there were no significant changes in the placebo group’s scores. Overall, our findings suggest that ubiquinol may modify bowel habits and enhance the quality of life for patients suffering from abdominal distress, despite the small drop in defecation frequency among those taking it.
Read More
9.5
We observed a fascinating case involving a patient with maternally inherited diabetes and deafness (MIDD) who experienced chronic intestinal pseudo obstruction. This condition, while not commonly reported in MIDD patients, illustrates the broader impact of the condition on various bodily systems.
Interestingly, despite most gastrointestinal symptoms like constipation and diarrhea being more prevalent, the introduction of Coenzyme Q10 as a treatment option led to a resolution of the pseudo obstruction. This finding gives us promising insights into how Coenzyme Q10 can aid in gastrointestinal health, particularly for patients facing complex mitochondrial disorders.
Although the report focuses on intestinal pseudo obstruction rather than constipation explicitly, the positive outcome from Coenzyme Q10 suggests it may play a supportive role in managing related gastrointestinal symptoms. By further exploring this connection, we can better understand the potential benefits of Coenzyme Q10 in similar clinical settings.
Interestingly, despite most gastrointestinal symptoms like constipation and diarrhea being more prevalent, the introduction of Coenzyme Q10 as a treatment option led to a resolution of the pseudo obstruction. This finding gives us promising insights into how Coenzyme Q10 can aid in gastrointestinal health, particularly for patients facing complex mitochondrial disorders.
Although the report focuses on intestinal pseudo obstruction rather than constipation explicitly, the positive outcome from Coenzyme Q10 suggests it may play a supportive role in managing related gastrointestinal symptoms. By further exploring this connection, we can better understand the potential benefits of Coenzyme Q10 in similar clinical settings.
Read More
Most Useful Reviews
9
Restores microbiome
These probiotics are of excellent quality. They significantly help with constipation and are essential for gut health. The compact packaging contains powdered probiotics that noticeably improve digestion after just a week of use.
Read More
1
Causes constipation
I chose this for its absorption rate, but unfortunately, it causes constipation, which is disappointing.
Read More
7.5
Improves digestion
Recommended, good packaging, fast delivery, and most importantly, it is effective. This brand has beneficial ingredients that aid in gastrointestinal absorption and address constipation. It is useful for overall nutrition and supports heart, skin, brain, and cardiovascular health.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.8
- All Researches
9.5
We observed a fascinating case involving a patient with maternally inherited diabetes and deafness (MIDD) who experienced chronic intestinal pseudo obstruction. This condition, while not commonly reported in MIDD patients, illustrates the broader impact of the condition on various bodily systems.
Interestingly, despite most gastrointestinal symptoms like constipation and diarrhea being more prevalent, the introduction of Coenzyme Q10 as a treatment option led to a resolution of the pseudo obstruction. This finding gives us promising insights into how Coenzyme Q10 can aid in gastrointestinal health, particularly for patients facing complex mitochondrial disorders.
Although the report focuses on intestinal pseudo obstruction rather than constipation explicitly, the positive outcome from Coenzyme Q10 suggests it may play a supportive role in managing related gastrointestinal symptoms. By further exploring this connection, we can better understand the potential benefits of Coenzyme Q10 in similar clinical settings.
Interestingly, despite most gastrointestinal symptoms like constipation and diarrhea being more prevalent, the introduction of Coenzyme Q10 as a treatment option led to a resolution of the pseudo obstruction. This finding gives us promising insights into how Coenzyme Q10 can aid in gastrointestinal health, particularly for patients facing complex mitochondrial disorders.
Although the report focuses on intestinal pseudo obstruction rather than constipation explicitly, the positive outcome from Coenzyme Q10 suggests it may play a supportive role in managing related gastrointestinal symptoms. By further exploring this connection, we can better understand the potential benefits of Coenzyme Q10 in similar clinical settings.
Read More
4
We conducted a study to examine how coenzyme Q10, in its reduced form known as ubiquinol, might affect constipation in individuals dealing with daily abdominal discomfort. Using a robust, double-blind, randomized control design, we enlisted forty-one patients who experienced either constipation or diarrhea. Participants were split evenly into two groups, with one receiving 150 mg of ubiquinol each day for twelve weeks, while the other group received a placebo.
Over the course of the study, we had participants keep a daily diary to monitor their defecation frequency and the consistency of their stools, following the Bristol Stool Form Scale. After twelve weeks, we noticed some interesting changes. The ubiquinol group reported a slight decrease in defecation frequency, averaging -0.1 times a day, while the placebo group saw an increase of +0.3 times a day. However, there was no significant change in stool form for the ubiquinol group, while the placebo group’s scores improved.
On the brighter side, we also found that the ubiquinol group experienced a notable improvement in their overall health perception, reflected in their quality of life scores. In contrast, there were no significant changes in the placebo group’s scores. Overall, our findings suggest that ubiquinol may modify bowel habits and enhance the quality of life for patients suffering from abdominal distress, despite the small drop in defecation frequency among those taking it.
Over the course of the study, we had participants keep a daily diary to monitor their defecation frequency and the consistency of their stools, following the Bristol Stool Form Scale. After twelve weeks, we noticed some interesting changes. The ubiquinol group reported a slight decrease in defecation frequency, averaging -0.1 times a day, while the placebo group saw an increase of +0.3 times a day. However, there was no significant change in stool form for the ubiquinol group, while the placebo group’s scores improved.
On the brighter side, we also found that the ubiquinol group experienced a notable improvement in their overall health perception, reflected in their quality of life scores. In contrast, there were no significant changes in the placebo group’s scores. Overall, our findings suggest that ubiquinol may modify bowel habits and enhance the quality of life for patients suffering from abdominal distress, despite the small drop in defecation frequency among those taking it.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Restores microbiome
These probiotics are of excellent quality. They significantly help with constipation and are essential for gut health. The compact packaging contains powdered probiotics that noticeably improve digestion after just a week of use.
Read More
1
Causes constipation
I chose this for its absorption rate, but unfortunately, it causes constipation, which is disappointing.
Read More
7.5
Improves digestion
Recommended, good packaging, fast delivery, and most importantly, it is effective. This brand has beneficial ingredients that aid in gastrointestinal absorption and address constipation. It is useful for overall nutrition and supports heart, skin, brain, and cardiovascular health.
Read More
Frequently Asked Questions
9
Restores microbiome
These probiotics are of excellent quality. They significantly help with constipation and are essential for gut health. The compact packaging contains powdered probiotics that noticeably improve digestion after just a week of use.
1
Causes constipation
I chose this for its absorption rate, but unfortunately, it causes constipation, which is disappointing.
4
We conducted a study to examine how coenzyme Q10, in its reduced form known as ubiquinol, might affect constipation in individuals dealing with daily abdominal discomfort. Using a robust, double-blind, randomized control design, we enlisted forty-one patients who experienced either constipation or diarrhea. Participants were split evenly into two groups, with one receiving 150 mg of ubiquinol each day for twelve weeks, while the other group received a placebo.
Over the course of the study, we had participants keep a daily diary to monitor their defecation frequency and the consistency of their stools, following the Bristol Stool Form Scale. After twelve weeks, we noticed some interesting changes. The ubiquinol group reported a slight decrease in defecation frequency, averaging -0.1 times a day, while the placebo group saw an increase of +0.3 times a day. However, there was no significant change in stool form for the ubiquinol group, while the placebo group’s scores improved.
On the brighter side, we also found that the ubiquinol group experienced a notable improvement in their overall health perception, reflected in their quality of life scores. In contrast, there were no significant changes in the placebo group’s scores. Overall, our findings suggest that ubiquinol may modify bowel habits and enhance the quality of life for patients suffering from abdominal distress, despite the small drop in defecation frequency among those taking it.
Over the course of the study, we had participants keep a daily diary to monitor their defecation frequency and the consistency of their stools, following the Bristol Stool Form Scale. After twelve weeks, we noticed some interesting changes. The ubiquinol group reported a slight decrease in defecation frequency, averaging -0.1 times a day, while the placebo group saw an increase of +0.3 times a day. However, there was no significant change in stool form for the ubiquinol group, while the placebo group’s scores improved.
On the brighter side, we also found that the ubiquinol group experienced a notable improvement in their overall health perception, reflected in their quality of life scores. In contrast, there were no significant changes in the placebo group’s scores. Overall, our findings suggest that ubiquinol may modify bowel habits and enhance the quality of life for patients suffering from abdominal distress, despite the small drop in defecation frequency among those taking it.
9.5
We observed a fascinating case involving a patient with maternally inherited diabetes and deafness (MIDD) who experienced chronic intestinal pseudo obstruction. This condition, while not commonly reported in MIDD patients, illustrates the broader impact of the condition on various bodily systems.
Interestingly, despite most gastrointestinal symptoms like constipation and diarrhea being more prevalent, the introduction of Coenzyme Q10 as a treatment option led to a resolution of the pseudo obstruction. This finding gives us promising insights into how Coenzyme Q10 can aid in gastrointestinal health, particularly for patients facing complex mitochondrial disorders.
Although the report focuses on intestinal pseudo obstruction rather than constipation explicitly, the positive outcome from Coenzyme Q10 suggests it may play a supportive role in managing related gastrointestinal symptoms. By further exploring this connection, we can better understand the potential benefits of Coenzyme Q10 in similar clinical settings.
Interestingly, despite most gastrointestinal symptoms like constipation and diarrhea being more prevalent, the introduction of Coenzyme Q10 as a treatment option led to a resolution of the pseudo obstruction. This finding gives us promising insights into how Coenzyme Q10 can aid in gastrointestinal health, particularly for patients facing complex mitochondrial disorders.
Although the report focuses on intestinal pseudo obstruction rather than constipation explicitly, the positive outcome from Coenzyme Q10 suggests it may play a supportive role in managing related gastrointestinal symptoms. By further exploring this connection, we can better understand the potential benefits of Coenzyme Q10 in similar clinical settings.
References
- Suzuki S, Gotoda T, Kusano C, Ikehara H, Miyakoshi Y, et al. Effect of Ubiquinol Intake on Defecation Frequency and Stool Form: A Prospective, Double-Blinded, Randomized Control Study. J Med Food. 2019;22:81. 10.1089/jmf.2018.4233
- Bergamin CS, Rolim LC, Dib SA, Moisés RS. Unusual occurrence of intestinal pseudo obstruction in a patient with maternally inherited diabetes and deafness (MIDD) and favorable outcome with coenzyme Q10. Arq Bras Endocrinol Metabol. 2008;52:1345. PubMed
