Last update
3/10/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 6 Reviews
8.2
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Coenzyme Q10 (Ubiquinone)
100 mg
†
Black Pepper Ext. (Piper nigrum) (fruit) (standardized to contain 95% Piperine) (BioPerine®)
5 mg
†
Top Medical Research Studies
7
Citicoline and CoQ10 protection study
We investigated how a combination of citicoline and coenzyme Q10 (CoQ10) might impact retinal cell health in a mouse model of ocular hypertension (OHT). Using four groups of mice, including those receiving the combination treatment and a control group, we aimed to understand if these substances could protect against the loss of retinal ganglion cells, which is a major concern in glaucoma.
The treatment was started 15 days prior to inducing ocular hypertension with a laser and continued until we examined the mice about a week later. Our findings were promising: the combination of citicoline and CoQ10 led to a temporary reduction in eye pressure shortly after treatment. Furthermore, it significantly prevented the death of specific retinal cells that are vital for vision.
While we were encouraged by these results, especially regarding cell protection, it's important to note that there were no significant impacts on neurons in the visual pathway areas we studied, like the dLGN. Overall, our research suggests that this combination might offer neuroprotective benefits in specific aspects of ocular hypertension, paving the way for further exploration into treatments that go beyond only lowering eye pressure.
The treatment was started 15 days prior to inducing ocular hypertension with a laser and continued until we examined the mice about a week later. Our findings were promising: the combination of citicoline and CoQ10 led to a temporary reduction in eye pressure shortly after treatment. Furthermore, it significantly prevented the death of specific retinal cells that are vital for vision.
While we were encouraged by these results, especially regarding cell protection, it's important to note that there were no significant impacts on neurons in the visual pathway areas we studied, like the dLGN. Overall, our research suggests that this combination might offer neuroprotective benefits in specific aspects of ocular hypertension, paving the way for further exploration into treatments that go beyond only lowering eye pressure.
Read More
Most Useful Reviews
9
Reduced blood pressure
6 people found this helpful
I have experienced no hypertension issues lately; however, my blood pressure did rise while taking this product. My mother, who deals with hypertension, has benefited greatly and has stable blood pressure levels now. I always ensure to keep it on hand.
Read More
7.5
Mandatory supplement
110 people found this helpful
I believe coenzyme Q10 is essential to take, especially after the age of 35. For those with cardiovascular issues, higher doses of 200-300 mg can be beneficial. It provides significant aid for hypertension.
Read More
9
Reduced cardiac risk
2 people found this helpful
"Health is true wealth, not gold or silver." A study involving 443 healthy Swedish individuals with an average age of 78 showed that those taking CoQ10 and selenium for 48 months had less than half the risk of cardiovascular mortality compared to a placebo group. This included a significant reduction in risk for individuals with hypertension. These findings suggest that a quality CoQ10 and selenium supplement could cut cardiac mortality risk substantially.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
- All Researches
7
Citicoline and CoQ10 protection study
We investigated how a combination of citicoline and coenzyme Q10 (CoQ10) might impact retinal cell health in a mouse model of ocular hypertension (OHT). Using four groups of mice, including those receiving the combination treatment and a control group, we aimed to understand if these substances could protect against the loss of retinal ganglion cells, which is a major concern in glaucoma.
The treatment was started 15 days prior to inducing ocular hypertension with a laser and continued until we examined the mice about a week later. Our findings were promising: the combination of citicoline and CoQ10 led to a temporary reduction in eye pressure shortly after treatment. Furthermore, it significantly prevented the death of specific retinal cells that are vital for vision.
While we were encouraged by these results, especially regarding cell protection, it's important to note that there were no significant impacts on neurons in the visual pathway areas we studied, like the dLGN. Overall, our research suggests that this combination might offer neuroprotective benefits in specific aspects of ocular hypertension, paving the way for further exploration into treatments that go beyond only lowering eye pressure.
The treatment was started 15 days prior to inducing ocular hypertension with a laser and continued until we examined the mice about a week later. Our findings were promising: the combination of citicoline and CoQ10 led to a temporary reduction in eye pressure shortly after treatment. Furthermore, it significantly prevented the death of specific retinal cells that are vital for vision.
While we were encouraged by these results, especially regarding cell protection, it's important to note that there were no significant impacts on neurons in the visual pathway areas we studied, like the dLGN. Overall, our research suggests that this combination might offer neuroprotective benefits in specific aspects of ocular hypertension, paving the way for further exploration into treatments that go beyond only lowering eye pressure.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reduced blood pressure
6 people found this helpful
I have experienced no hypertension issues lately; however, my blood pressure did rise while taking this product. My mother, who deals with hypertension, has benefited greatly and has stable blood pressure levels now. I always ensure to keep it on hand.
Read More
7.5
Mandatory supplement
110 people found this helpful
I believe coenzyme Q10 is essential to take, especially after the age of 35. For those with cardiovascular issues, higher doses of 200-300 mg can be beneficial. It provides significant aid for hypertension.
Read More
9
Reduced cardiac risk
2 people found this helpful
"Health is true wealth, not gold or silver." A study involving 443 healthy Swedish individuals with an average age of 78 showed that those taking CoQ10 and selenium for 48 months had less than half the risk of cardiovascular mortality compared to a placebo group. This included a significant reduction in risk for individuals with hypertension. These findings suggest that a quality CoQ10 and selenium supplement could cut cardiac mortality risk substantially.
Read More
6
Normalises pressure quickly
1 people found this helpful
My mother and her husband take this supplement alongside Omega 3. It's effective at quickly reducing hypertension, but its effects last about two hours before medication is required again. Therefore, I always recommend keeping it handy.
Read More
7.5
Hypertension significantly reduced
Using coenzyme Q10 has led to significant improvement in my family's hypertension, leading to notably lower blood pressure levels. They have said it's effective after consistent use.
Read More
Frequently Asked Questions
7.5
Hypertension significantly reduced
Using coenzyme Q10 has led to significant improvement in my family's hypertension, leading to notably lower blood pressure levels. They have said it's effective after consistent use.
6
Normalises pressure quickly
1 people found this helpful
My mother and her husband take this supplement alongside Omega 3. It's effective at quickly reducing hypertension, but its effects last about two hours before medication is required again. Therefore, I always recommend keeping it handy.
7.5
Mandatory supplement
110 people found this helpful
I believe coenzyme Q10 is essential to take, especially after the age of 35. For those with cardiovascular issues, higher doses of 200-300 mg can be beneficial. It provides significant aid for hypertension.
References
- Matamoros JA, Rubio-Casado S, Fernández-Albarral JA, Martínez-López MA, Salobrar-García E, et al. Neuroprotective Effect of the Combination of Citicoline and CoQ10 in a Mouse Model of Ocular Hypertension. Antioxidants (Basel). 2024;14. 10.3390/antiox14010004
Data last updated:
