' 
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
USERS' SCORE
Good
Based on 5 Reviews
8.8
Supplement Facts
Serving Size: 4 capsules
Amount Per Serving
%DV
Chloride (from glucosamine hydrochloride potassium sulfate)
170 mg
7%
Sodium (from chondroitin sulfate sodium)
120 mg
5%
Potassium (from glucosamine hydrochloride potassium sulfate)
190 mg
4%
GlucosamineHydrochloride Potassium Sulfate
1500 mg
†
Chondroitin sulfate Sodium
1200 mg
†
MSM (Methylsulfonylmethane)(OptiMSM®)
1000 mg
†
Top Medical Research Studies
7
MSM anal cancer treatment feasibility
Piloting of a Screen‑Triage‑Treat Surgical Approach Model for Management of Anal Cancer in Liberia.
Highlights MSM-specific challenges
We explored the challenges faced by men who have sex with men (MSM) regarding anal cancer treatment in Liberia. With limited access to screening and care for anal cancers, we aimed to investigate whether a screen-triage-treat approach could effectively help identify and manage anal high-grade squamous intraepithelial lesions (aHSIL) within this vulnerable population.
In our study, we collaborated with local organizations to gather data from MSM and transgender individuals. Participants were recruited and engaged in self-swabbing to test for high-risk human papillomavirus (HPV), alongside HIV testing. Those who tested positive for aHSIL were offered further evaluation and treatment using high-resolution anoscopy and infrared coagulation.
Among 110 participants, a significant number turned out to be living with HIV, and nearly half tested positive for high-risk HPV. This indicates a notable health concern. While 68% of those who tested positive opted for further procedures, we found that this model effectively presented a potential solution for identifying anal cancer risks and can work in a low-resource environment.
Overall, our findings suggest that implementing a screen-triage-treat model shows promise for reducing anal cancer incidence among MSM in Liberia. This approach, previously successful in cervical cancer management, might become a crucial tool in cancer prevention strategies for similar low- and middle-income countries.
In our study, we collaborated with local organizations to gather data from MSM and transgender individuals. Participants were recruited and engaged in self-swabbing to test for high-risk human papillomavirus (HPV), alongside HIV testing. Those who tested positive for aHSIL were offered further evaluation and treatment using high-resolution anoscopy and infrared coagulation.
Among 110 participants, a significant number turned out to be living with HIV, and nearly half tested positive for high-risk HPV. This indicates a notable health concern. While 68% of those who tested positive opted for further procedures, we found that this model effectively presented a potential solution for identifying anal cancer risks and can work in a low-resource environment.
Overall, our findings suggest that implementing a screen-triage-treat model shows promise for reducing anal cancer incidence among MSM in Liberia. This approach, previously successful in cervical cancer management, might become a crucial tool in cancer prevention strategies for similar low- and middle-income countries.
Read More
5
Moderate efficacy, high recurrence
Electrocautery ablation therapy for anal intraepithelial carcinoma with high-resolution anoscopy.
MSM-focused cancer treatment insights
We investigated the effectiveness and safety of electrocautery ablation for treating high-grade squamous intraepithelial lesions (HSILs) in men who have sex with men (MSM), including those living with HIV. Our study included 20 participants who underwent this treatment and were followed closely with high-resolution anoscopy (HRA) to monitor outcomes.
The primary goal was to see how well this approach worked at curing local HSILs after six months. While electrocautery ablation was noted to be moderately effective, we also discovered that the recurrence rates were quite high. This suggests that even with comprehensive biopsies from the anal canal, we could not fully prevent the return of these lesions.
Overall, our findings highlight that while this treatment can be helpful for MSM, the risk of recurrence is significant. More research involving larger participant groups and longer follow-ups is necessary to improve treatment outcomes. We believe it is crucial to continue refining strategies for managing HSIL to enhance the health of this community.
The primary goal was to see how well this approach worked at curing local HSILs after six months. While electrocautery ablation was noted to be moderately effective, we also discovered that the recurrence rates were quite high. This suggests that even with comprehensive biopsies from the anal canal, we could not fully prevent the return of these lesions.
Overall, our findings highlight that while this treatment can be helpful for MSM, the risk of recurrence is significant. More research involving larger participant groups and longer follow-ups is necessary to improve treatment outcomes. We believe it is crucial to continue refining strategies for managing HSIL to enhance the health of this community.
Read More
7
Meyna spinosa shows anticancer promise
Phytochemical Characterization, Prooxidant, Antiproliferative and Anti-Inflammatory Potential of Meyna spinosa Roxb. Ex Link Ripe Fruit.
Moderate relevance to cancer therapy
We investigated the effects of methanolic extracts from the fruit of Meyna spinosa on cancer cells. Our findings highlighted that both the methanolic extract and the ethyl acetate extract displayed antiproliferative properties, particularly against A549 and MCF7 cancer cell lines.
As we increased the concentration of these extracts and the duration of exposure, we observed a consistent reduction in cell viability, indicating that these extracts may inhibit cancer growth. Moreover, the extracts showed promising antioxidant activity which suggests additional mechanisms at play in potentially combating cancer.
Importantly, while these results are encouraging, they stem from laboratory observations, and further research would be necessary to translate these effects into clinical applications or comprehensive treatment options for cancer patients. Overall, our analysis gives a glimpse into the potential of Meyna spinosa fruit extracts in cancer therapy but also underscores the need for more studies to confirm these findings.
As we increased the concentration of these extracts and the duration of exposure, we observed a consistent reduction in cell viability, indicating that these extracts may inhibit cancer growth. Moreover, the extracts showed promising antioxidant activity which suggests additional mechanisms at play in potentially combating cancer.
Importantly, while these results are encouraging, they stem from laboratory observations, and further research would be necessary to translate these effects into clinical applications or comprehensive treatment options for cancer patients. Overall, our analysis gives a glimpse into the potential of Meyna spinosa fruit extracts in cancer therapy but also underscores the need for more studies to confirm these findings.
Read More
Most Useful Reviews
9.5
Reduces cancer risk
Glucosamine sulfate is a simple sugar that prevents glucose oxidation. The dosage is critical; for an 80 kg person, 2000 mg daily can lead to heart issues and reduced lifespan if taken young. However, studies reveal that for those over 50, glucosamine is linked to a 41% lower risk of mortality from respiratory infections and a significant reduction in lung and colorectal cancer risks. Though I don’t take it as I’m still young, it provides my grandmother with crucial relief for her knees and potentially extends her life.
Read More
9.5
Pain relief
After breast cancer treatment, I experienced severe joint pain from the anti-hormone drug Sodium bisulfate. This discomfort affected my daily life. A friend introduced me to glucosamine with chondroitin MSM and UCII, and after taking it, my joint pain in hands and feet improved noticeably. I am very pleased with the results and plan to continue purchasing this product.
Read More
8.8
Anti-cancer properties
The product significantly reduces joint pain and enhances my quality of life. It possesses anti-inflammatory effects, increases glutathione levels, and minimizes muscle damage, thereby accelerating recovery post-exercise. Furthermore, it alleviates pain and stiffness, which helps manage arthritis symptoms, and reduces inflammation, relieving allergy symptoms. I feel it boosts my immunity and maintains my overall health, and I appreciate its anti-cancer properties, alongside its ability to prevent or treat ulcers.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
- All Researches
7
Meyna spinosa shows anticancer promise
Phytochemical Characterization, Prooxidant, Antiproliferative and Anti-Inflammatory Potential of Meyna spinosa Roxb. Ex Link Ripe Fruit.
Moderate relevance to cancer therapy
We investigated the effects of methanolic extracts from the fruit of Meyna spinosa on cancer cells. Our findings highlighted that both the methanolic extract and the ethyl acetate extract displayed antiproliferative properties, particularly against A549 and MCF7 cancer cell lines.
As we increased the concentration of these extracts and the duration of exposure, we observed a consistent reduction in cell viability, indicating that these extracts may inhibit cancer growth. Moreover, the extracts showed promising antioxidant activity which suggests additional mechanisms at play in potentially combating cancer.
Importantly, while these results are encouraging, they stem from laboratory observations, and further research would be necessary to translate these effects into clinical applications or comprehensive treatment options for cancer patients. Overall, our analysis gives a glimpse into the potential of Meyna spinosa fruit extracts in cancer therapy but also underscores the need for more studies to confirm these findings.
As we increased the concentration of these extracts and the duration of exposure, we observed a consistent reduction in cell viability, indicating that these extracts may inhibit cancer growth. Moreover, the extracts showed promising antioxidant activity which suggests additional mechanisms at play in potentially combating cancer.
Importantly, while these results are encouraging, they stem from laboratory observations, and further research would be necessary to translate these effects into clinical applications or comprehensive treatment options for cancer patients. Overall, our analysis gives a glimpse into the potential of Meyna spinosa fruit extracts in cancer therapy but also underscores the need for more studies to confirm these findings.
Read More
7
MSM anal cancer treatment feasibility
Piloting of a Screen‑Triage‑Treat Surgical Approach Model for Management of Anal Cancer in Liberia.
Highlights MSM-specific challenges
We explored the challenges faced by men who have sex with men (MSM) regarding anal cancer treatment in Liberia. With limited access to screening and care for anal cancers, we aimed to investigate whether a screen-triage-treat approach could effectively help identify and manage anal high-grade squamous intraepithelial lesions (aHSIL) within this vulnerable population.
In our study, we collaborated with local organizations to gather data from MSM and transgender individuals. Participants were recruited and engaged in self-swabbing to test for high-risk human papillomavirus (HPV), alongside HIV testing. Those who tested positive for aHSIL were offered further evaluation and treatment using high-resolution anoscopy and infrared coagulation.
Among 110 participants, a significant number turned out to be living with HIV, and nearly half tested positive for high-risk HPV. This indicates a notable health concern. While 68% of those who tested positive opted for further procedures, we found that this model effectively presented a potential solution for identifying anal cancer risks and can work in a low-resource environment.
Overall, our findings suggest that implementing a screen-triage-treat model shows promise for reducing anal cancer incidence among MSM in Liberia. This approach, previously successful in cervical cancer management, might become a crucial tool in cancer prevention strategies for similar low- and middle-income countries.
In our study, we collaborated with local organizations to gather data from MSM and transgender individuals. Participants were recruited and engaged in self-swabbing to test for high-risk human papillomavirus (HPV), alongside HIV testing. Those who tested positive for aHSIL were offered further evaluation and treatment using high-resolution anoscopy and infrared coagulation.
Among 110 participants, a significant number turned out to be living with HIV, and nearly half tested positive for high-risk HPV. This indicates a notable health concern. While 68% of those who tested positive opted for further procedures, we found that this model effectively presented a potential solution for identifying anal cancer risks and can work in a low-resource environment.
Overall, our findings suggest that implementing a screen-triage-treat model shows promise for reducing anal cancer incidence among MSM in Liberia. This approach, previously successful in cervical cancer management, might become a crucial tool in cancer prevention strategies for similar low- and middle-income countries.
Read More
5
Moderate efficacy, high recurrence
Electrocautery ablation therapy for anal intraepithelial carcinoma with high-resolution anoscopy.
MSM-focused cancer treatment insights
We investigated the effectiveness and safety of electrocautery ablation for treating high-grade squamous intraepithelial lesions (HSILs) in men who have sex with men (MSM), including those living with HIV. Our study included 20 participants who underwent this treatment and were followed closely with high-resolution anoscopy (HRA) to monitor outcomes.
The primary goal was to see how well this approach worked at curing local HSILs after six months. While electrocautery ablation was noted to be moderately effective, we also discovered that the recurrence rates were quite high. This suggests that even with comprehensive biopsies from the anal canal, we could not fully prevent the return of these lesions.
Overall, our findings highlight that while this treatment can be helpful for MSM, the risk of recurrence is significant. More research involving larger participant groups and longer follow-ups is necessary to improve treatment outcomes. We believe it is crucial to continue refining strategies for managing HSIL to enhance the health of this community.
The primary goal was to see how well this approach worked at curing local HSILs after six months. While electrocautery ablation was noted to be moderately effective, we also discovered that the recurrence rates were quite high. This suggests that even with comprehensive biopsies from the anal canal, we could not fully prevent the return of these lesions.
Overall, our findings highlight that while this treatment can be helpful for MSM, the risk of recurrence is significant. More research involving larger participant groups and longer follow-ups is necessary to improve treatment outcomes. We believe it is crucial to continue refining strategies for managing HSIL to enhance the health of this community.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.8
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Reduces cancer risk
Glucosamine sulfate is a simple sugar that prevents glucose oxidation. The dosage is critical; for an 80 kg person, 2000 mg daily can lead to heart issues and reduced lifespan if taken young. However, studies reveal that for those over 50, glucosamine is linked to a 41% lower risk of mortality from respiratory infections and a significant reduction in lung and colorectal cancer risks. Though I don’t take it as I’m still young, it provides my grandmother with crucial relief for her knees and potentially extends her life.
Read More
9.5
Pain relief
After breast cancer treatment, I experienced severe joint pain from the anti-hormone drug Sodium bisulfate. This discomfort affected my daily life. A friend introduced me to glucosamine with chondroitin MSM and UCII, and after taking it, my joint pain in hands and feet improved noticeably. I am very pleased with the results and plan to continue purchasing this product.
Read More
8.8
Anti-cancer properties
The product significantly reduces joint pain and enhances my quality of life. It possesses anti-inflammatory effects, increases glutathione levels, and minimizes muscle damage, thereby accelerating recovery post-exercise. Furthermore, it alleviates pain and stiffness, which helps manage arthritis symptoms, and reduces inflammation, relieving allergy symptoms. I feel it boosts my immunity and maintains my overall health, and I appreciate its anti-cancer properties, alongside its ability to prevent or treat ulcers.
Read More
9.5
Reduces joint pain
VERY HELPFUL FOR PAIN. For those new to MSM, I recommend reading THE MIRACLE OF MSM by Dr. Stanley Jacob. I suffered severe joint pain, worrying I might have cancer in my legs! My protocol using hyaluronic acid and collagen II combined with MSM has me nearly pain-free. Curcumin, quercetin, and targeted supplements can significantly reduce inflammation without steroids' adverse effects.
Read More
8.8
Anti-cancer action
The main beneficial ingredients of this product are impressive. It effectively lowers cholesterol, strengthens the cardiovascular system, suppresses inflammation, and exhibits anti-cancer properties while reducing the risk of blood clots. I consistently take this product due to its high quality and its proven beneficial effects. If you find this information valuable, please click YES. Thank you!
Read More
