Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.8
USERS' SCORE
Good
Based on 19 Reviews
8.4
Supplement Facts
Serving Size: 2 Quick Release Capsule
Amount Per Serving
%DV
Sambucus Black Elderberry(Sambucus nigra) (fruit)(from 31.25 mg of 64:1 extract or 200 mg of 10:1 extract)
2,000 mg (2 g)
*
Top Medical Research Studies
9
We delved into how elderberry, specifically from the black elderberry fruit, impacts the flu virus, H1N1. Using an innovative technique called Direct Analysis in Real Time Mass Spectrometry (DART TOF-MS), we were able to identify the powerful anti-viral properties of elderberry extract without the need for complicated processes like separation or derivatization.
Our findings revealed that elderberry extract does indeed inhibit H1N1 infection in a lab setting, with an effective concentration (IC50) of 252 micrograms per milliliter. Interestingly, we discovered that flavonoids present in the elderberry bind to H1N1 virions—essentially blocking their ability to infect host cells.
Among the compounds, two key flavonoids emerged: the 5,7,3',4'-tetra-O-methylquercetin and dihydromyricetin. These compounds not only bound to the virus but also effectively prevented infection. Notably, the tetra-O-methylquercetin demonstrated an impressive IC50 of just 0.13 micrograms per milliliter, which is comparable to well-known antiviral medications like Oseltamivir and Amantadine.
In summary, elderberry shows promising potential as a natural remedy against the H1N1 flu, offering a fascinating area for further research and utilization in flu prevention strategies.
Our findings revealed that elderberry extract does indeed inhibit H1N1 infection in a lab setting, with an effective concentration (IC50) of 252 micrograms per milliliter. Interestingly, we discovered that flavonoids present in the elderberry bind to H1N1 virions—essentially blocking their ability to infect host cells.
Among the compounds, two key flavonoids emerged: the 5,7,3',4'-tetra-O-methylquercetin and dihydromyricetin. These compounds not only bound to the virus but also effectively prevented infection. Notably, the tetra-O-methylquercetin demonstrated an impressive IC50 of just 0.13 micrograms per milliliter, which is comparable to well-known antiviral medications like Oseltamivir and Amantadine.
In summary, elderberry shows promising potential as a natural remedy against the H1N1 flu, offering a fascinating area for further research and utilization in flu prevention strategies.
Read More
8
Elderberry effective against flu pathogens
We aimed to investigate the effectiveness of a standardized elderberry extract against influenza viruses and respiratory bacterial pathogens. The study utilized liquid cultures to examine how various concentrations of the elderberry extract—specifically 5%, 10%, 15%, and 20%—inhibited bacterial growth.
Our findings revealed that the elderberry extract is not just a potential ally against flu viruses, but also demonstrates activity against several harmful bacteria. We specifically tested its effects on both H5N1-type influenza A and influenza B viruses using reputable laboratory methods.
The results suggest that elderberry could offer additional strategies for combating infections, particularly during the flu season when complications often arise from bacterial super-infections following viral illnesses. These findings encourage the exploration of natural products like elderberry as a supportive treatment for respiratory infections.
Our findings revealed that the elderberry extract is not just a potential ally against flu viruses, but also demonstrates activity against several harmful bacteria. We specifically tested its effects on both H5N1-type influenza A and influenza B viruses using reputable laboratory methods.
The results suggest that elderberry could offer additional strategies for combating infections, particularly during the flu season when complications often arise from bacterial super-infections following viral illnesses. These findings encourage the exploration of natural products like elderberry as a supportive treatment for respiratory infections.
Read More
7
We evaluated the effectiveness of elderberry juice, specifically concentrated juice (CJ-E), in combating the human influenza A virus (IFV). Our experiments involved administering CJ-E to mice infected with IFV to observe any potential antiviral effects. While we found that CJ-E had a strong impact on the mice, its antiviral action was less impressive when tested in a controlled cell culture environment.
To further assess its effects, we separated CJ-E into different fractions using ultrafiltration and anion-exchange chromatography. We concentrated on the high-molecular-weight fractions of CJ-E, which appeared to significantly suppress viral replication in the mice's bronchoalveolar lavage fluids (BALFs). Moreover, these fractions seemed to boost the production of IFV-specific neutralizing antibodies in the serum, along with increasing secretory IgA levels in BALFs and feces.
Particularly, one fraction, Fr. II from the high-molecular-weight group, which contained acidic polysaccharides, showed notable strength in defending against the flu infection. In conclusion, our findings suggest that CJ-E can stimulate the immune response and may play a preventative role against the influenza virus infection.
To further assess its effects, we separated CJ-E into different fractions using ultrafiltration and anion-exchange chromatography. We concentrated on the high-molecular-weight fractions of CJ-E, which appeared to significantly suppress viral replication in the mice's bronchoalveolar lavage fluids (BALFs). Moreover, these fractions seemed to boost the production of IFV-specific neutralizing antibodies in the serum, along with increasing secretory IgA levels in BALFs and feces.
Particularly, one fraction, Fr. II from the high-molecular-weight group, which contained acidic polysaccharides, showed notable strength in defending against the flu infection. In conclusion, our findings suggest that CJ-E can stimulate the immune response and may play a preventative role against the influenza virus infection.
Read More
Most Useful Reviews
8.8
Protected from flu
I absolutely love these! They have no taste, are easy to swallow, and help keep my husband and me healthy. All five of my kids had the stomach flu this winter. Despite being around them while they were unwell, my husband and I started taking the elderberry three times a day and felt better. Amazingly, we never got sick!
Read More
9.5
Fast flu recovery
We swear by elderberry in our home; it's proven effective for us in preventing and speeding up flu recovery. When I caught the flu, I was back to normal in less than a week. My two-year-old daughter had no symptoms for more than one day after using the gummies. We've tried various brands, but we always come back to these capsules for adults; they're easier to swallow and offer more doses for a better price. We'll continue buying from this brand!
Read More
8.8
Alleviates flu symptoms
I chose this black elderberry product after reviewing many options. My holistic doctor recommended it for its effectiveness in combating viruses. Given the current fears regarding the coronavirus, I've been taking one daily to maintain my health. With various viruses and flus circulating, these seem to help alleviate symptoms and reduce recovery time. Highly recommend!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.8
- All Researches
9
We explored how European black elderberry affects the immune response, particularly regarding flu infections. Through comparing its water extract and polysaccharide fractions to a traditional alcoholic extract, we focused on the role of dendritic cells (DCs), which are crucial for triggering strong T cell responses.
Our findings showed that the water extract and its polysaccharide components effectively matured DCs, enhancing their ability to stimulate T cells significantly. In contrast, the traditional alcoholic extract did not demonstrate any capacity to induce T cell stimulation.
We also observed that the water extracts promoted the production of key inflammatory cytokines like IL-6, TNF-α, and IFN-γ, contributing to a robust immune response, which may be beneficial in fighting off viruses like influenza. Thus, it appears that the polysaccharides from elderberry extracts can play a significant role in modulating the immune system, potentially equipping us to better combat viral threats.
Our findings showed that the water extract and its polysaccharide components effectively matured DCs, enhancing their ability to stimulate T cells significantly. In contrast, the traditional alcoholic extract did not demonstrate any capacity to induce T cell stimulation.
We also observed that the water extracts promoted the production of key inflammatory cytokines like IL-6, TNF-α, and IFN-γ, contributing to a robust immune response, which may be beneficial in fighting off viruses like influenza. Thus, it appears that the polysaccharides from elderberry extracts can play a significant role in modulating the immune system, potentially equipping us to better combat viral threats.
Read More
9
We assessed the effectiveness of black elderberry (Sambucus nigra) in treating upper respiratory symptoms, particularly those associated with the flu. The study included 180 participants and examined various factors, such as vaccination status and the underlying causes of symptoms.
Our findings indicated that elderberry supplementation significantly reduced upper respiratory symptoms, offering a promising alternative for those seeking relief without relying on over-the-counter medications or antibiotics. The analysis revealed a strong positive impact, suggesting that elderberry could be particularly beneficial for treating symptoms arising from viral infections.
Overall, this research indicates that elderberry can serve as a safer, effective option for managing flu symptoms and common colds. This could help address concerns about antibiotic misuse and provide a more natural remedy during flu season.
Our findings indicated that elderberry supplementation significantly reduced upper respiratory symptoms, offering a promising alternative for those seeking relief without relying on over-the-counter medications or antibiotics. The analysis revealed a strong positive impact, suggesting that elderberry could be particularly beneficial for treating symptoms arising from viral infections.
Overall, this research indicates that elderberry can serve as a safer, effective option for managing flu symptoms and common colds. This could help address concerns about antibiotic misuse and provide a more natural remedy during flu season.
Read More
9
We delved into how elderberry, specifically from the black elderberry fruit, impacts the flu virus, H1N1. Using an innovative technique called Direct Analysis in Real Time Mass Spectrometry (DART TOF-MS), we were able to identify the powerful anti-viral properties of elderberry extract without the need for complicated processes like separation or derivatization.
Our findings revealed that elderberry extract does indeed inhibit H1N1 infection in a lab setting, with an effective concentration (IC50) of 252 micrograms per milliliter. Interestingly, we discovered that flavonoids present in the elderberry bind to H1N1 virions—essentially blocking their ability to infect host cells.
Among the compounds, two key flavonoids emerged: the 5,7,3',4'-tetra-O-methylquercetin and dihydromyricetin. These compounds not only bound to the virus but also effectively prevented infection. Notably, the tetra-O-methylquercetin demonstrated an impressive IC50 of just 0.13 micrograms per milliliter, which is comparable to well-known antiviral medications like Oseltamivir and Amantadine.
In summary, elderberry shows promising potential as a natural remedy against the H1N1 flu, offering a fascinating area for further research and utilization in flu prevention strategies.
Our findings revealed that elderberry extract does indeed inhibit H1N1 infection in a lab setting, with an effective concentration (IC50) of 252 micrograms per milliliter. Interestingly, we discovered that flavonoids present in the elderberry bind to H1N1 virions—essentially blocking their ability to infect host cells.
Among the compounds, two key flavonoids emerged: the 5,7,3',4'-tetra-O-methylquercetin and dihydromyricetin. These compounds not only bound to the virus but also effectively prevented infection. Notably, the tetra-O-methylquercetin demonstrated an impressive IC50 of just 0.13 micrograms per milliliter, which is comparable to well-known antiviral medications like Oseltamivir and Amantadine.
In summary, elderberry shows promising potential as a natural remedy against the H1N1 flu, offering a fascinating area for further research and utilization in flu prevention strategies.
Read More
8
We examined how elderberry might impact flu treatment based on several studies. From 1995 to 2013, three clinical trials looked specifically at different elderberry preparations, and all concluded that elderberry could be effective against influenza. However, it's important to note that these studies involved only 77 people, which is quite small for drawing definitive conclusions.
While the potential for elderberry's effectiveness seems promising, the limited sample size means we should be cautious in making broad claims about its benefits. There were no human or animal studies mentioned that specifically researched the safety of elderberry during pregnancy, presenting a gap in knowledge that is concerning for pregnant women considering herbal treatments for flu.
Overall, while elderberry appears effective against the flu based on the small trials, we need much more comprehensive research to better understand its efficacy and safety, particularly for vulnerable populations like pregnant women.
While the potential for elderberry's effectiveness seems promising, the limited sample size means we should be cautious in making broad claims about its benefits. There were no human or animal studies mentioned that specifically researched the safety of elderberry during pregnancy, presenting a gap in knowledge that is concerning for pregnant women considering herbal treatments for flu.
Overall, while elderberry appears effective against the flu based on the small trials, we need much more comprehensive research to better understand its efficacy and safety, particularly for vulnerable populations like pregnant women.
Read More
8
Elderberry effective against flu pathogens
We aimed to investigate the effectiveness of a standardized elderberry extract against influenza viruses and respiratory bacterial pathogens. The study utilized liquid cultures to examine how various concentrations of the elderberry extract—specifically 5%, 10%, 15%, and 20%—inhibited bacterial growth.
Our findings revealed that the elderberry extract is not just a potential ally against flu viruses, but also demonstrates activity against several harmful bacteria. We specifically tested its effects on both H5N1-type influenza A and influenza B viruses using reputable laboratory methods.
The results suggest that elderberry could offer additional strategies for combating infections, particularly during the flu season when complications often arise from bacterial super-infections following viral illnesses. These findings encourage the exploration of natural products like elderberry as a supportive treatment for respiratory infections.
Our findings revealed that the elderberry extract is not just a potential ally against flu viruses, but also demonstrates activity against several harmful bacteria. We specifically tested its effects on both H5N1-type influenza A and influenza B viruses using reputable laboratory methods.
The results suggest that elderberry could offer additional strategies for combating infections, particularly during the flu season when complications often arise from bacterial super-infections following viral illnesses. These findings encourage the exploration of natural products like elderberry as a supportive treatment for respiratory infections.
Read More
User Reviews
USERS' SCORE
Good
Based on 19 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Protected from flu
I absolutely love these! They have no taste, are easy to swallow, and help keep my husband and me healthy. All five of my kids had the stomach flu this winter. Despite being around them while they were unwell, my husband and I started taking the elderberry three times a day and felt better. Amazingly, we never got sick!
Read More
9.5
Fast flu recovery
We swear by elderberry in our home; it's proven effective for us in preventing and speeding up flu recovery. When I caught the flu, I was back to normal in less than a week. My two-year-old daughter had no symptoms for more than one day after using the gummies. We've tried various brands, but we always come back to these capsules for adults; they're easier to swallow and offer more doses for a better price. We'll continue buying from this brand!
Read More
8.8
Alleviates flu symptoms
I chose this black elderberry product after reviewing many options. My holistic doctor recommended it for its effectiveness in combating viruses. Given the current fears regarding the coronavirus, I've been taking one daily to maintain my health. With various viruses and flus circulating, these seem to help alleviate symptoms and reduce recovery time. Highly recommend!
Read More
9.5
Prevents winter flu
I haven't caught a cold since using this. I purchased it to prevent the winter flu and colds. Since I started taking it, I've remained well. It's highly concentrated and offers good value for money. I'll buy it again.
Read More
9.5
No more colds
The best! I haven't caught a cold or the flu since I started taking these supplements.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Stich L, Plattner S, McDougall G, Austin C, Steinkasserer A. Polysaccharides from European Black Elderberry Extract Enhance Dendritic Cell Mediated T Cell Immune Responses. Int J Mol Sci. 2022;23. doi:10.3390/ijms23073949
- Wieland LS, Piechotta V, Feinberg T, Ludeman E, Hutton B, et al. Elderberry for prevention and treatment of viral respiratory illnesses: a systematic review. BMC Complement Med Ther. 2021;21:112. doi:10.1186/s12906-021-03283-5
- Hawkins J, Baker C, Cherry L, Dunne E. Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Complement Ther Med. 2019;42:361. doi:10.1016/j.ctim.2018.12.004
- Shahsavandi S, Ebrahimi MM, Hasaninejad Farahani A. Interfering With Lipid Raft Association: A Mechanism to Control Influenza Virus Infection By . Iran J Pharm Res. 2017;16:1147.
- Holst L, Havnen GC, Nordeng H. Echinacea and elderberry-should they be used against upper respiratory tract infections during pregnancy?. Front Pharmacol. 2014;5:31. doi:10.3389/fphar.2014.00031
- Kinoshita E, Hayashi K, Katayama H, Hayashi T, Obata A. Anti-influenza virus effects of elderberry juice and its fractions. Biosci Biotechnol Biochem. 2012;76:1633.
- Krawitz C, Mraheil MA, Stein M, Imirzalioglu C, Domann E, et al. Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses. BMC Complement Altern Med. 2011;11:16. doi:10.1186/1472-6882-11-16
- Roschek B, Fink RC, McMichael MD, Li D, Alberte RS. Elderberry flavonoids bind to and prevent H1N1 infection in vitro. Phytochemistry. 2009;70:1255. doi:10.1016/j.phytochem.2009.06.003
