' 
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1/4 Level Teaspoon (1.1 g)
Amount Per Serving
%DV
Vitamin C (Ascorbic Acid)
1.1 g (1,100 mg)
1222%
Top Medical Research Studies
8
Vitamin C intake linked to depression
Association of dietary vitamin C intake with depression in adults: A cross-sectional study of NHANES from 2005 to 2020.
Highly relevant dietary study
This study aimed to understand how dietary vitamin C affects depression in adults. By analyzing data from the National Health and Nutrition Examination Survey spanning from 2005 to 2020, we focused on the relationship between vitamin C intake and depression levels among 38,157 participants.
Our findings revealed that individuals who consumed higher amounts of vitamin C had lower odds of experiencing depression. Specifically, those in the higher intake quartiles showed significantly reduced odds compared to those with the lowest intake. Interestingly, we discovered an L-shaped curve representing the relationship between vitamin C and depression, suggesting that while increased intake was beneficial up to a certain point (around 93.61 mg), higher consumption did not yield additional benefits.
While our results are promising, it's crucial to note that this was a cross-sectional study, meaning we cannot definitively claim that vitamin C intake causes changes in depression. Additionally, other factors might have influenced these associations, which we couldn't fully control for.
Overall, this research provides intriguing evidence of the potential role that dietary vitamin C might play in alleviating depressive symptoms, especially for those consuming lower amounts.
Our findings revealed that individuals who consumed higher amounts of vitamin C had lower odds of experiencing depression. Specifically, those in the higher intake quartiles showed significantly reduced odds compared to those with the lowest intake. Interestingly, we discovered an L-shaped curve representing the relationship between vitamin C and depression, suggesting that while increased intake was beneficial up to a certain point (around 93.61 mg), higher consumption did not yield additional benefits.
While our results are promising, it's crucial to note that this was a cross-sectional study, meaning we cannot definitively claim that vitamin C intake causes changes in depression. Additionally, other factors might have influenced these associations, which we couldn't fully control for.
Overall, this research provides intriguing evidence of the potential role that dietary vitamin C might play in alleviating depressive symptoms, especially for those consuming lower amounts.
Read More
7
SunGold kiwifruit boosts vitamin C
SunGold Kiwifruit Consumption Restores Adequate to Optimal Vitamin C Status in People with a History of Severe Respiratory Infections.
Modest link to depression reduction
We explored whether consuming SunGold kiwifruit could help restore sufficient vitamin C levels in people who have suffered from severe respiratory infections. Over six weeks, participants consumed two kiwifruits a day, which is about 300 mg of vitamin C.
Before the study, many participants had low intakes of fruits and vegetables, and their vitamin C levels were often inadequate. After the kiwifruit intervention, we observed that around 80% of the participants managed to boost their vitamin C levels to a good range.
Notably, along with improved vitamin C status, participants reported less fatigue and fewer feelings of depression. This suggests that vitamin C might play a role in enhancing mood, although further investigation is needed to fully understand its effects.
However, about 20% of the participants still struggled to reach adequate vitamin C levels, especially those who smoked or had higher body weight. Overall, our findings indicate that adding kiwifruit to the diet may provide mood-enhancing benefits while improving vitamin C status.
Before the study, many participants had low intakes of fruits and vegetables, and their vitamin C levels were often inadequate. After the kiwifruit intervention, we observed that around 80% of the participants managed to boost their vitamin C levels to a good range.
Notably, along with improved vitamin C status, participants reported less fatigue and fewer feelings of depression. This suggests that vitamin C might play a role in enhancing mood, although further investigation is needed to fully understand its effects.
However, about 20% of the participants still struggled to reach adequate vitamin C levels, especially those who smoked or had higher body weight. Overall, our findings indicate that adding kiwifruit to the diet may provide mood-enhancing benefits while improving vitamin C status.
Read More
8
Vitamin C and depression study
Higher serum ascorbic acid levels are associated with lower depression prevalence in US adults: a case-control study.
Significant but not conclusive
We explored the connection between serum ascorbic acid levels—commonly known as vitamin C—and depression in US adults. The study involved data from over 3,400 participants from the National Health and Nutrition Examination Survey. By comparing individuals diagnosed with depression to those without, we aimed to uncover whether higher vitamin C levels could be linked to lower rates of depression.
Our findings were quite revealing. We observed that individuals with depression had significantly lower serum ascorbic acid levels compared to non-depressed individuals. Specifically, the average vitamin C level in those with depression was about 43 μmol/L, while it was around 53 μmol/L for those without depression.
The research indicated a clear trend: as vitamin C levels increased, the prevalence of depression decreased. In fact, the data showed that individuals in the highest quartile of vitamin C levels had a depression prevalence of just 5.4%, compared to 12.0% in the lowest quartile.
While this correlation suggests that higher vitamin C levels might help reduce the risk of depression, it’s important to note that the study did not test vitamin C as a treatment for depression directly. Therefore, while the association is noteworthy, we cannot definitively say that vitamin C supplementation will resolve depressive symptoms.
Our findings were quite revealing. We observed that individuals with depression had significantly lower serum ascorbic acid levels compared to non-depressed individuals. Specifically, the average vitamin C level in those with depression was about 43 μmol/L, while it was around 53 μmol/L for those without depression.
The research indicated a clear trend: as vitamin C levels increased, the prevalence of depression decreased. In fact, the data showed that individuals in the highest quartile of vitamin C levels had a depression prevalence of just 5.4%, compared to 12.0% in the lowest quartile.
While this correlation suggests that higher vitamin C levels might help reduce the risk of depression, it’s important to note that the study did not test vitamin C as a treatment for depression directly. Therefore, while the association is noteworthy, we cannot definitively say that vitamin C supplementation will resolve depressive symptoms.
Read More
Most Useful Reviews
9.5
Improved depression
Vitamin B12 supplements should be methylcobalamin, as it is better absorbed than cyanocobalamin, especially for those with IBS. It's excellent; I strongly recommend it. It has raised my B12 levels and helped treat my depression.
Read More
7.5
Effective for depression
This product is excellent and versatile. If you can overlook its slightly tart taste, it's an effective vitamin C supplement. It's vital for many bodily functions, aids in inflammation, fatigue, and is particularly helpful for my depression.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.5
- All Researches
9
Vitamin C counters stress-related depression
Vitamin C improved anxiety and depression like behavior induced by chronic unpredictable mild stress in adolescent rats by influencing on oxidative stress balance, neurotransmitter systems, and inflammatory response.
Addressed potential vitamin C benefits
We explored the impact of vitamin C on anxiety and depression behaviors prompted by chronic unpredictable mild stress (CUMS) in adolescent male rats. The study investigated whether exposure to this type of stress during adolescence could lead to mood-related issues in adulthood, and if vitamin C could help alleviate these problems.
Our research utilized several behavioral tests to measure anxiety and depression levels. We also examined how CUMS affected serotonin metabolism, inflammation levels, oxidative stress, and brain-derived neurotrophic factor (BDNF) in the brain tissue of the rats.
Our findings indicated that CUMS indeed worsened mood-related behaviors by negatively affecting the brain's balance between oxidative stress, inflammation, and serotonin levels. However, rats that received both CUMS treatment and vitamin C showed promising results. This co-treatment helped reverse the negative effects induced by CUMS, suggesting that vitamin C may restore the disturbed biochemical parameters.
Overall, we propose that vitamin C supplementation could be a safe and effective strategy for managing stress-induced anxiety and depression.
Our research utilized several behavioral tests to measure anxiety and depression levels. We also examined how CUMS affected serotonin metabolism, inflammation levels, oxidative stress, and brain-derived neurotrophic factor (BDNF) in the brain tissue of the rats.
Our findings indicated that CUMS indeed worsened mood-related behaviors by negatively affecting the brain's balance between oxidative stress, inflammation, and serotonin levels. However, rats that received both CUMS treatment and vitamin C showed promising results. This co-treatment helped reverse the negative effects induced by CUMS, suggesting that vitamin C may restore the disturbed biochemical parameters.
Overall, we propose that vitamin C supplementation could be a safe and effective strategy for managing stress-induced anxiety and depression.
Read More
8
Vitamin C alleviates withdrawal depression
Ascorbic acid supplementation in adolescent rats ameliorates anxiety-like and depressive-like manifestations of nicotine-ethanol abstinence: Role of oxidative stress, inflammatory, and serotonergic mechanisms.
Moderate relevance due to complexities
We explored the effects of vitamin C on anxiety and depression linked to abstinence from nicotine and ethanol in adolescent male rats. The study was carefully structured, dividing the rats into several groups, including a control group and various treatment groups receiving different doses of vitamin C during the withdrawal phase.
Our results suggested that vitamin C supplementation effectively reduced anxiety- and depressive-like behaviors. This was observed through various behavioral tests, such as the elevated plus maze and forced swimming test, indicating that the rats receiving vitamin C exhibited improved mood and reduced anxiety.
Notably, vitamin C appeared to enhance the antioxidant defense system, lower inflammation, and promote serotonin levels—important factors in mood regulation. While there were many facets at play due to the combined effects of nicotine and ethanol, the positive impact of vitamin C supplementation stands out as a potential therapeutic approach for managing withdrawal symptoms.
Overall, the findings highlight vitamin C's promising role in improving mental health during challenging withdrawal periods, making it a valuable supplement for further exploration in human studies.
Our results suggested that vitamin C supplementation effectively reduced anxiety- and depressive-like behaviors. This was observed through various behavioral tests, such as the elevated plus maze and forced swimming test, indicating that the rats receiving vitamin C exhibited improved mood and reduced anxiety.
Notably, vitamin C appeared to enhance the antioxidant defense system, lower inflammation, and promote serotonin levels—important factors in mood regulation. While there were many facets at play due to the combined effects of nicotine and ethanol, the positive impact of vitamin C supplementation stands out as a potential therapeutic approach for managing withdrawal symptoms.
Overall, the findings highlight vitamin C's promising role in improving mental health during challenging withdrawal periods, making it a valuable supplement for further exploration in human studies.
Read More
8
Dietary antioxidants and depression
Association between Dietary Antioxidant Capacity in Midlife and Depressive Symptoms in Late Life: The Singapore Chinese Health Study.
Study confirms antioxidant benefits
We examined how midlife dietary intake of antioxidants, including vitamin C, relates to depressive symptoms in older age among a large group of Chinese participants in Singapore. By analyzing data from over 13,000 individuals, we were able to see clear patterns connecting antioxidant consumption—specifically from vitamins C and E, as well as carotenoids and flavonoids—to mental health outcomes.
Participants, initially assessed at a mean age of 52, were later evaluated for depressive symptoms around age 73. The results revealed that higher intakes of antioxidants were linked with reduced odds of experiencing depression. In fact, those with the highest consumption showed significantly lower likelihoods of developing depressive symptoms.
This reinforces the importance of an antioxidant-rich diet, suggesting that such dietary choices might help in preventing depression in later life. Though we didn't isolate vitamin C's effects from the other antioxidants, its presence in a balanced diet could contribute positively to mental health.
Participants, initially assessed at a mean age of 52, were later evaluated for depressive symptoms around age 73. The results revealed that higher intakes of antioxidants were linked with reduced odds of experiencing depression. In fact, those with the highest consumption showed significantly lower likelihoods of developing depressive symptoms.
This reinforces the importance of an antioxidant-rich diet, suggesting that such dietary choices might help in preventing depression in later life. Though we didn't isolate vitamin C's effects from the other antioxidants, its presence in a balanced diet could contribute positively to mental health.
Read More
8
Vitamin C intake linked to depression
Association of dietary vitamin C intake with depression in adults: A cross-sectional study of NHANES from 2005 to 2020.
Highly relevant dietary study
This study aimed to understand how dietary vitamin C affects depression in adults. By analyzing data from the National Health and Nutrition Examination Survey spanning from 2005 to 2020, we focused on the relationship between vitamin C intake and depression levels among 38,157 participants.
Our findings revealed that individuals who consumed higher amounts of vitamin C had lower odds of experiencing depression. Specifically, those in the higher intake quartiles showed significantly reduced odds compared to those with the lowest intake. Interestingly, we discovered an L-shaped curve representing the relationship between vitamin C and depression, suggesting that while increased intake was beneficial up to a certain point (around 93.61 mg), higher consumption did not yield additional benefits.
While our results are promising, it's crucial to note that this was a cross-sectional study, meaning we cannot definitively claim that vitamin C intake causes changes in depression. Additionally, other factors might have influenced these associations, which we couldn't fully control for.
Overall, this research provides intriguing evidence of the potential role that dietary vitamin C might play in alleviating depressive symptoms, especially for those consuming lower amounts.
Our findings revealed that individuals who consumed higher amounts of vitamin C had lower odds of experiencing depression. Specifically, those in the higher intake quartiles showed significantly reduced odds compared to those with the lowest intake. Interestingly, we discovered an L-shaped curve representing the relationship between vitamin C and depression, suggesting that while increased intake was beneficial up to a certain point (around 93.61 mg), higher consumption did not yield additional benefits.
While our results are promising, it's crucial to note that this was a cross-sectional study, meaning we cannot definitively claim that vitamin C intake causes changes in depression. Additionally, other factors might have influenced these associations, which we couldn't fully control for.
Overall, this research provides intriguing evidence of the potential role that dietary vitamin C might play in alleviating depressive symptoms, especially for those consuming lower amounts.
Read More
8
Vitamin C and depression study
Higher serum ascorbic acid levels are associated with lower depression prevalence in US adults: a case-control study.
Significant but not conclusive
We explored the connection between serum ascorbic acid levels—commonly known as vitamin C—and depression in US adults. The study involved data from over 3,400 participants from the National Health and Nutrition Examination Survey. By comparing individuals diagnosed with depression to those without, we aimed to uncover whether higher vitamin C levels could be linked to lower rates of depression.
Our findings were quite revealing. We observed that individuals with depression had significantly lower serum ascorbic acid levels compared to non-depressed individuals. Specifically, the average vitamin C level in those with depression was about 43 μmol/L, while it was around 53 μmol/L for those without depression.
The research indicated a clear trend: as vitamin C levels increased, the prevalence of depression decreased. In fact, the data showed that individuals in the highest quartile of vitamin C levels had a depression prevalence of just 5.4%, compared to 12.0% in the lowest quartile.
While this correlation suggests that higher vitamin C levels might help reduce the risk of depression, it’s important to note that the study did not test vitamin C as a treatment for depression directly. Therefore, while the association is noteworthy, we cannot definitively say that vitamin C supplementation will resolve depressive symptoms.
Our findings were quite revealing. We observed that individuals with depression had significantly lower serum ascorbic acid levels compared to non-depressed individuals. Specifically, the average vitamin C level in those with depression was about 43 μmol/L, while it was around 53 μmol/L for those without depression.
The research indicated a clear trend: as vitamin C levels increased, the prevalence of depression decreased. In fact, the data showed that individuals in the highest quartile of vitamin C levels had a depression prevalence of just 5.4%, compared to 12.0% in the lowest quartile.
While this correlation suggests that higher vitamin C levels might help reduce the risk of depression, it’s important to note that the study did not test vitamin C as a treatment for depression directly. Therefore, while the association is noteworthy, we cannot definitively say that vitamin C supplementation will resolve depressive symptoms.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Improved depression
Vitamin B12 supplements should be methylcobalamin, as it is better absorbed than cyanocobalamin, especially for those with IBS. It's excellent; I strongly recommend it. It has raised my B12 levels and helped treat my depression.
7.5
Effective for depression
This product is excellent and versatile. If you can overlook its slightly tart taste, it's an effective vitamin C supplement. It's vital for many bodily functions, aids in inflammation, fatigue, and is particularly helpful for my depression.
