Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 95 Researches
8
USERS' SCORE
Good
Based on 20 Reviews
8.8
Supplement Facts
Serving Size: 1 Chewable
Amount Per Serving
%DV
Calories
5
 
Total Fat
0 g
0%
Sodium
0 mg
0%
Total Carbohydrate
1 g
0%
Total Sugars
less than 1 g
 
Includes 0 g Added Sugars
 
0%
Vitamin C*
30 mg
33%
Vitamin D** (as D3)
10 mcg (400 IU)
50%
Kids Probiotic BlendLactobacillus acidophilusLactobacillus gasseriLactobacillus paracaseiLactobacillus plantarumLactobacillus caseiLactobacillus brevisLactobacillus rhamnosusLactobacillus salivariusLactobacillus bulgaricusTotal Lacto Cultures (4 Billion CFU)Bifidobacterium lactisBifidobacterium breveBifidobacterium infantisBifidobacterium bifidumBifidobacterium longumTotal Bifido Cultures (1 Billion CFU)
71 mg
+
Total Probiotic Cultures
5 Billion CFU1
 
Organic Prebiotic Fiber BlendOrganic Acacia Fiber (A. senegal), Organic Whole Cranberry (Vaccinium macrocarpon) (fruit), Organic Emblic (Amla, Phyllanthus emblica) (fruit) Extract
310 mg
+

Top Medical Research Studies

9.5
Bifidobacterium lactis reduced diarrhea duration
We explored the impact of Bifidobacterium animalis subsp. lactis BLa80 on diarrhea in young children through a well-structured, randomized, double-blinded, placebo-controlled study.

Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.

Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.

This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
Read More
9
Lactobacillus effectively reduces diarrhea
We explored the impact of Lactobacillus salivarius SNK-6 on treating and preventing diarrhea in pigeons. In our research, we compared healthy pigeons with those infected with specific strains of E. coli known to cause diarrhea. After administering L. salivarius SNK-6, we observed a notable reduction in diarrhea among treated pigeons, while control pigeons still experienced a 10% incidence of diarrhea. This suggests that boosting levels of Lactobacillus can help maintain a healthy balance in the gut, potentially preventing diarrhea in the future.
Read More
9
Bifidobacterium lactis helps reduce diarrhea
We evaluated the effectiveness of Bifidobacterium lactis XLTG11 in treating acute watery diarrhea in children through a rigorous randomized, double-blind, placebo-controlled trial.

Children who received the probiotic alongside their conventional treatment had significantly shorter diarrhea durations and hospital stays compared to those who only got standard care. Additionally, those taking Bifidobacterium showed better improvement rates and healthier gut microbiomes after treatment.

Overall, this study suggests that Bifidobacterium lactis can be a beneficial adjunct therapy for children suffering from diarrhea.
Read More

Most Useful Reviews

10
Forgot about diarrhoea
My 2-year-old had stool issues after antibiotics for over a month. On a friend's recommendation, I bought these probiotics and after three weeks, I forgot about diarrhoea as a nightmare. They also helped prevent illness in kindergarten.
Read More
10
Eliminated diarrhoea
I got rid of diarrhoea completely.
Read More
10
Probiotics for all
Probiotics effectively removed the diarrhea from both my son and my dog. I plan to buy more for my grandparents as well. A good product overall.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 95 Researches
8
  • All Researches
9.5
Probiotics aid IBS-D treatment outcomes
We explored the impact of Lactobacillus acidophilus and L. plantarum on patients suffering from diarrhea-predominant irritable bowel syndrome (IBS-D). In a randomized, single-blinded clinical trial of 100 patients, some received standard IBS treatment alone while others added probiotics to their therapy.

After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
Read More
9.5
Probiotics aid IBS-D treatment outcomes
We explored the impact of Lactobacillus acidophilus and L. plantarum on patients suffering from diarrhea-predominant irritable bowel syndrome (IBS-D). In a randomized, single-blinded clinical trial of 100 patients, some received standard IBS treatment alone while others added probiotics to their therapy.

After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
Read More
9.5
Lactobacillus shows promise for diarrhea
We aimed to explore how Lactobacillus acidophilus can help relieve diarrhea symptoms associated with irritable bowel syndrome (IBS) and antibiotic-associated diarrhea (AAD).

In a study with 54 patients, those taking the probiotic Neobiotic Lactobalance® for 21 days saw significant reductions in diarrhea severity and abdominal pain, with scores dropping impressively on the Gastrointestinal Symptom Rating Scale.

Fecal analysis indicated improved intestinal health, highlighting Lactobacillus's potential benefits for those struggling with these conditions.
Read More
9.5
Probiotics improve H. pylori treatments
We analyzed various studies on incorporating probiotics into treatments for Helicobacter pylori (H. pylori) infection. Our findings revealed that adding probiotics like Bifidobacterium longum improved the eradication rate significantly.

Specifically, we noted that the probiotic group experienced fewer side effects, including diarrhea, nausea, and abdominal pain. This suggests that probiotics could not only enhance the effectiveness of H. pylori treatment but also make it more comfortable for patients. Overall, these results support the use of probiotics in gastric therapies.
Read More
9.5
Bifidobacterium longum shows promise
We conducted a randomized double-blind, placebo-controlled trial with 200 participants to see how well the probiotic CECT 7347 (ES1) and its heat-treated version (HT-ES1) could help those suffering from diarrhea-predominant irritable bowel syndrome (IBS-D). After 12 weeks of treatment, both ES1 and HT-ES1 showed significant improvements in symptom severity, with marked reductions in IBS-SSS scores compared to the placebo.

Secondary benefits included better stool consistency and quality of life, making these treatments promising options for managing IBS-D symptoms. These findings reflect meaningful advancements in probiotic and postbiotic solutions.
Read More

User Reviews

USERS' SCORE
Good
Based on 20 Reviews
8.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Forgot about diarrhoea
My 2-year-old had stool issues after antibiotics for over a month. On a friend's recommendation, I bought these probiotics and after three weeks, I forgot about diarrhoea as a nightmare. They also helped prevent illness in kindergarten.
Read More
10
Eliminated diarrhoea
I got rid of diarrhoea completely.
Read More
10
Probiotics for all
Probiotics effectively removed the diarrhea from both my son and my dog. I plan to buy more for my grandparents as well. A good product overall.
Read More
10
Effective for diarrhoea
This product works really well against diarrhea! I began giving it to my child on the first day of illness, and within two days, she was fine. The taste is pleasant, like strawberry, and it’s easy to use - just chew it. It is suitable for a 2-year-old. I believe the quality is high, being rich in beneficial ingredients.
Read More
9.5
Effective during illness
Before bedtime, I gave these probiotics to my children. They were especially helpful during illness when there was vomiting and diarrhoea. They aided in a quick recovery. My 3 and 6-year-olds chew them with pleasure, despite the large tablet size.
Read More

Frequently Asked Questions

Diarrhea is a condition characterized by the frequent passage of loose or watery stools, which can occur due to various factors, including infections, dietary choices, and underlying health conditions. It often results from the body's response to an irritation of the gastrointestinal tract, which can be caused by viruses, bacteria, parasites, or certain medications. While most cases tend to be short-lived and resolve on their own, diarrhea can lead to dehydration, especially in vulnerable populations such as young children and the elderly.

Managing diarrhea typically involves staying hydrated by drinking clear fluids and, when necessary, replenishing lost electrolytes. In some cases, over-the-counter medications may provide relief, although it’s essential to consult a healthcare professional for persistent or severe symptoms. A focus on bland, easy-to-digest foods can also help during recovery. Remember, if diarrhea persists for more than a couple of days or is accompanied by other concerning symptoms—like high fever, severe abdominal pain, or blood in stools—seeking medical attention is crucial.

Children's probiotics are dietary supplements specifically formulated to provide beneficial bacteria that support digestive health and the immune system in children. These probiotics contain various strains of live microorganisms, often including Lactobacillus and Bifidobacterium, which are known to help maintain a healthy balance of gut bacteria. The gut microbiome plays a crucial role in children's overall health, influencing their digestion, immune function, and even mood. Many parents turn to children's probiotics to help address issues like constipation, diarrhea, or colic, as well as to support their child’s immunity, especially during cold and flu season.

When selecting a children's probiotic, it’s essential to consider factors such as the specific strains included, the number of colony-forming units (CFUs), and whether it is tailored to your child's specific health needs. Probiotics can come in various forms, including powders, gummies, and liquids, making them easy to administer to little ones. However, it’s always advisable to consult a pediatrician before starting any new supplement regime for your child, as they can provide personalized recommendations based on the child's health history and current needs.

Children's probiotics can potentially help alleviate diarrhea, especially if it's caused by antibiotics or a viral infection. Probiotics are beneficial bacteria that help maintain a healthy gut microbiome and can improve overall digestive health. In some studies, specific strains of probiotics, such as Lactobacillus rhamnosus and Saccharomyces boulardii, have been shown to shorten the duration and severity of diarrhea in children. These probiotics work by restoring the natural balance of bacteria in the gut and can help counteract the harmful effects of pathogens that cause diarrhea.

However, it's important to note that not all probiotics are created equal, and their effectiveness can vary based on the specific strains used and the individual child's health situation. While many parents find that probiotics can be a helpful addition to their child's diet during bouts of diarrhea, it's always best to consult with a pediatrician before starting any supplementation. This is particularly crucial if the child is very young, has underlying health conditions, or if the diarrhea is persistent, as these factors may require different treatment approaches.

Based on user reviews, the time it typically takes to see results from this probiotic supplement for diarrhea varies. Some users report significant improvements within just one to two days. For example, one reviewer mentioned that after starting the probiotics on the first day of illness, their child was fine within two days (Read Review). Another user indicated that their child experienced adjusted bowel function within ten days after starting the medication (Read Review).

However, other users found that it took a bit longer to see results. One parent noted significant improvements after more than two weeks of consistent use (Read Review). Overall, while many users experience quick relief from diarrhea symptoms, the duration for full effectiveness can vary, and consistent use may be beneficial.

The use of probiotics for managing diarrhea is extensively supported by scientific research, notably strains such as Lactobacillus acidophilus and Bifidobacterium bifidum. A study demonstrated that Lactobacillus acidophilus significantly improved outcomes in children suffering from rotavirus enteritis, leading to faster relief from diarrhea compared to standard care ([3]). Additionally, research involving probiotics also highlights their effectiveness in alleviating diarrhea related to antibiotic use, with findings indicating that they can reduce both the incidence and duration of antibiotic-associated diarrhea in children ([66], [87]).

Moreover, a systematic review showed promising results in treating acute diarrhea in children with probiotics, signifying a noticeable reduction in the duration of diarrhea ([90]). The benefits extend to other demographics as well; for instance, research has indicated that specific probiotic strains can aid in managing diarrhea symptoms in adults with irritable bowel syndrome and in patients undergoing chemotherapy ([83]). Overall, these findings endorse the incorporation of probiotics as a viable approach for mitigating diarrhea across various populations.

Based on user reviews, many parents report significant improvements in their children's symptoms of diarrhea after using these probiotics. Several users indicated that their children experienced a complete resolution of diarrhea, with one parent stating, "I got rid of diarrhoea completely" (Read Review). Another parent shared their positive experience, noting how these probiotics helped their child recover quickly from severe diarrhea after antibiotics, stating the symptoms improved within just two days of use (Read Review).

Other reviewers emphasized the probiotics' effectiveness in managing diarrhea during various illnesses, highlighting their children's quick recovery from symptoms like vomiting and stomach pain (Read Review). Some users reported consistent use led to normalized bowel movements over time, illustrating the potential for improving gut health beyond immediate relief (Read Review). Overall, while individual results can vary, many users have found that these probiotics significantly alleviated diarrhea symptoms, contributing positively to their children's health.

Users have reported positive experiences when combining this supplement with other products to manage diarrhea. One review indicated that while the probiotics were effective, a combination with Lactobif helped improve symptoms during a case of gastroenteritis, suggesting that the probiotics had a milder effect on their own (Read Review). This points to the potential benefits of using these probiotics alongside other treatments for quicker relief.

Additionally, some users noted the use of probiotics not only for immediate relief but also as a preventive measure. One reviewer mentioned consistently giving these probiotics during the autumn-spring period, showcasing their versatility in preventing diarrhea in children (Read Review). Overall, while individual results may vary, users suggest exploring combinations with other supplements to enhance the effectiveness of managing diarrhea.

Research suggests that an optimal dose of probiotics for treating diarrhea in children typically ranges between 5 to 10 billion CFUs (colony-forming units) per day, particularly using strains like Lactobacillus rhamnosus and Lactobacillus acidophilus. For example, in a study where Lactobacillus rhamnosus was used, children showed significant improvements in diarrhea symptoms and faster recovery rates compared to placebo groups. The children receiving these probiotics experienced shorter durations of diarrhea and improved fecal consistency, proving the effectiveness of such strains in managing acute gastroenteritis in children [66] [32].

It's essential to consider that while probiotics can be beneficial, the quality and strain of the probiotic are crucial for effectiveness. Specifically, the combination of probiotics with other treatments, like zinc, has shown promise in enhancing recovery from diarrhea. In a study where probiotics were paired with zinc, children demonstrated quicker recovery times from diarrhea compared to those receiving probiotics alone, underscoring the potential of synergistic treatments [35] [74]. Overall, when selecting probiotics for treating diarrhea in children, look for products that contain established strains and appropriate dosing to ensure optimal outcomes.

10
Effective for diarrhoea
This product works really well against diarrhea! I began giving it to my child on the first day of illness, and within two days, she was fine. The taste is pleasant, like strawberry, and it’s easy to use - just chew it. It is suitable for a 2-year-old. I believe the quality is high, being rich in beneficial ingredients.
9.5
Regulated child's stool
These probiotics were a lifesaver after a course of antibiotics. My child had unformed stools and then faced terrifying diarrhea and abdominal pain. I ordered them immediately, and they worked beautifully. Probiotics adjusted his chair perfectly within 10 days. Although I followed a strict diet to enhance the effect, now everything functions normally.
8.8
Significant improvement
I purchased probiotics for my son. After more than two weeks, there was a significant improvement. He previously had diarrhoea, but now his bowel movements are normal, and he will continue taking them.
10
Eliminated diarrhoea
I got rid of diarrhoea completely.
9.5
Effective during illness
Before bedtime, I gave these probiotics to my children. They were especially helpful during illness when there was vomiting and diarrhoea. They aided in a quick recovery. My 3 and 6-year-olds chew them with pleasure, despite the large tablet size.
8
Milder effect
I give it to my 2-year-old son half a tablet after dinner. It’s delicious! However, in cases of gastroenteritis, diarrhoea persisted but improved with some lactobif that I took. The effect was milder without it.
9
Good for diarrhoea
Garden of Life is a remarkable brand with quality products. These probiotics effectively help with diarrhoea, and I also give them during the autumn-spring period as a preventive measure.
9
Lactobacillus acidophilus aids diarrhea recovery
We explored the impact of Lactobacillus acidophilus paired with montmorillonite powder on children suffering from rotavirus enteritis. In a study involving 94 kids, we divided them into two groups. One received standard care, while the other got the probiotic treatment as well. After five days, we found that children receiving the compound had faster relief from diarrhea, vomiting, fever, and dehydration. While there was an improvement in inflammatory responses, the difference in C-reactive protein levels wasn’t significant, and both groups reported a similar rate of side effects.
9
Probiotics beneficial for antibiotic diarrhea
We examined the effectiveness of probiotics in preventing antibiotic-associated diarrhea (AAD) among adult patients. Conducted across several hospitals, our study included 340 participants who received either probiotics or a placebo soon after starting antibiotics.

The results showed that probiotics, specifically Lactobacillus rhamnosus GG and Bifidobacterium longum BB536, significantly reduced both the incidence and duration of AAD. High adherence rates and positive patient feedback added to the supportive findings for probiotics' role in gut health during antibiotic treatment.
We explored the effects of a multispecies probiotic, featuring Bifidobacterium lactis, on preventing antibiotic-associated diarrhea (AAD) in children aged 3 months to 18 years. In a rigorous randomized trial comprising 350 participants across various settings, we found that the probiotic didn't significantly reduce the risk of AAD. However, it did help lower the overall occurrences of diarrhea during and up to a week after antibiotic use. This highlights the complexity of measuring AAD and its impact on study outcomes.
We investigated whether Bifidobacterium lactis CCT 7858 could help reduce antibiotic-related diarrhea in hospitalized patients. In a rigorous double-blind, randomized, placebo-controlled trial with 104 participants, we found that a significant percentage—about 74.5%—of those taking the probiotic experienced no diarrhea. Additionally, fewer patients reported abdominal distension in the B. lactis group compared to the placebo. While this strain showed promise in alleviating gastrointestinal discomfort, it’s essential to note that some secondary outcomes were modest. Overall, B. lactis appears safe and may offer notable benefits alongside antibiotics.
9
Bifidobacterium lactis improves diarrhea
We set out to examine how the probiotic Neobiotic Lactobalance®, which includes bifidobacterium lactis, affects diarrhea linked to irritable bowel syndrome (IBS) and antibiotic-associated diarrhea (AAD).

Our study involved 54 patients who took one capsule daily for three weeks. We found significant improvements; those with IBS reported a decrease in diarrhea symptoms from 17 to 6 points, while AAD patients saw reductions from 13 to 3 points on a standard symptom scale.

The treatment also helped restore healthy intestinal bacteria, suggesting that Neobiotic Lactobalance® effectively tackles the issues associated with these forms of diarrhea.
8
EPSs mitigate Salmonella-induced diarrhea
We explored how exopolysaccharides (EPSs) from Lactobacillus rhamnosus GG can help combat diarrhea caused by Salmonella typhimurium (S.T). In a study with mice, we observed that EPSs reduced the immune response to S.T infection by targeting specific signaling pathways involved in inflammation. This treatment also promoted beneficial bacterial clustering, which could help protect the intestinal lining from harmful bacteria invasion. Our findings suggest promising potential for EPSs in supporting gut health, particularly during bacterial infections.
We explored how Ligilactobacillus salivarius PS21603 can reduce post-weaning diarrhea in piglets. Utilizing a controlled study with 384 weaned piglets, we divided them into groups receiving different doses of the probiotic.

Our findings revealed that piglets receiving higher doses had improved intestinal morphology and lower faecal E. coli counts after 28 days. However, while overall gut microbiota diversity increased, no significant differences were noted among the treatment groups.

Ultimately, L. salivarius PS21603 demonstrated potential as a beneficial feed additive for managing diarrheal issues in young piglets.
8
We examined how well different treatments work for children with acute gastroenteritis, focusing on dietary recommendations, zinc, and probiotics.

In a well-structured study, infants were split into four groups: one received dietary advice only, another got probiotics including bifidobacterium longum, the third was given zinc, and the last group received both probiotics and zinc.

The results revealed that the combination of probiotics and zinc significantly sped up recovery from diarrhea compared to the other treatments. This suggests that using both of these together may be a more effective option for treating this condition in children.

References

  1. Li S, Lu T, Lin Z, Zhang Y, Zhou X, et al. Supplementation with probiotics co-cultivation improves the reproductive performance in a sow-piglet model by mother-infant microbiota transmission and placental mTOR signaling. World J Microbiol Biotechnol. 2024;41:13. doi:10.1007/s11274-024-04222-5
  2. Hashem B, Gaston M, Carlisle JD, Van Wick P. COMPARISON OF HAND-REARED PRONGHORN () MILK REPLACER COMPOSITIONS AND GROWTH RATES. J Zoo Wildl Med. 2024;55:1056. doi:10.1638/2023-0112
  3. Wei Q, Song LY, Rao R, Yang HW, Wen YP, et al. The Impact of Combined Therapy with Lactobacillus acidophilus and Montmorillonite Powder on the Inflammatory Response in Pediatric Rotavirus Enteritis. Int Arch Allergy Immunol. 2024. doi:10.1159/000542593
  4. Jeong JJ, Jin YJ, Ganesan R, Park HJ, Min BH, et al. Multistrain Probiotics Alleviate Diarrhea by Modulating Microbiome-Derived Metabolites and Serotonin Pathway. Probiotics Antimicrob Proteins. 2024. doi:10.1007/s12602-024-10232-4
  5. Alharbi BF, Alateek AA. Investigating the influence of probiotics in preventing Traveler's diarrhea: Meta-analysis based systematic review. Travel Med Infect Dis. 2024;59:102703. doi:10.1016/j.tmaid.2024.102703
  6. Miranda-Yuquilema J, Taboada J, Once V, Coyago M, Briñez W. Effect of Agroindustrial Waste Substrate Fermented with Lactic Acid Bacteria and Yeast on Changes in the Gut Microbiota of Guinea Pigs. Microorganisms. 2024;12. doi:10.3390/microorganisms12010133
  7. Shanshal SA, Alsaaty MH, Al-Qazaz H, Al-Zidan RN. Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial. Ceska Slov Farm. 2024;72:233.
  8. Shanshal SA, Alsaaty MH, Al-Qazaz H, Al-Zidan RN. Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial. Ceska Slov Farm. 2024;73:233.
  9. Higuchi T, Furuichi M, Maeda N, Tsugawa T, Ito K. Effects of probiotics in children with acute gastroenteritis: A systematic review and meta-analysis focusing on probiotics utilized in Japan. J Infect Chemother. 2024;30:337. doi:10.1016/j.jiac.2023.11.005
  10. Drozdov VN, Shikh EV, Astapovskii AA, Khalaidzheva KN, Solovieva SA, et al. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea and antibiotic-associated diarrhea]. Vopr Pitan. 2023;92:92. doi:10.33029/0042-8833-2023-92-4-92-103
  11. Lukasik J, Dierikx T, Besseling-van der Vaart I, de Meij T, Szajewska H. Multispecies Probiotic for the Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Clinical Trial. JAMA Pediatr. 2022;176:860. doi:10.1001/jamapediatrics.2022.1973
  12. Huang R, Xing HY, Liu HJ, Chen ZF, Tang BB. Efficacy of probiotics in the treatment of acute diarrhea in children: a systematic review and meta-analysis of clinical trials. Transl Pediatr. 2021;10:3248. doi:10.21037/tp-21-511
  13. Gandhar JS, De UK, Kala A, Malik YS, Yadav S, et al. Efficacy of Microencapsulated Probiotic as Adjunct Therapy on Resolution of Diarrhea, Copper-Zinc Homeostasis, Immunoglobulins, and Inflammatory Markers in Serum of Spontaneous Rotavirus-Infected Diarrhoetic Calves. Probiotics Antimicrob Proteins. 2022;14:1054. doi:10.1007/s12602-021-09862-9
  14. Kumar M, Kala A, Chaudhary LC, Agarwal N, Kochewad SA. Microencapsulated and Lyophilized Lactobacillus acidophilus Improved Gut Health and Immune Status of Preruminant Calves. Probiotics Antimicrob Proteins. 2022;14:523. doi:10.1007/s12602-021-09821-4
  15. Chorawala MR, Chauhan S, Patel R, Shah G. Cell Wall Contents of Probiotics (Lactobacillus species) Protect Against Lipopolysaccharide (LPS)-Induced Murine Colitis by Limiting Immuno-inflammation and Oxidative Stress. Probiotics Antimicrob Proteins. 2021;13:1005. doi:10.1007/s12602-020-09738-4
  16. Gunaratnam S, Diarra C, Paquette PD, Ship N, Millette M, et al. The Acid-Dependent and Independent Effects of Lactobacillus acidophilus CL1285, Lacticaseibacillus casei LBC80R, and Lacticaseibacillus rhamnosus CLR2 on Clostridioides difficile R20291. Probiotics Antimicrob Proteins. 2021;13:949. doi:10.1007/s12602-020-09729-5
  17. Shin I, Kang Y, Ahn J, Kim Y, Nam J, et al. The potential probiotic role of Lacticaseibacillus rhamnosus on growth performance, gut health, and immune responses of weaned pigs. J Anim Sci. 2025. doi:10.1093/jas/skaf089
  18. Chen K, Zeng K, Jin S, Ma Y, Cai L, et al. LRa05 in the treatment of acute diarrhea in children: a randomized controlled trial. Front Nutr. 2024;11:1479186. doi:10.3389/fnut.2024.1479186
  19. Gwee KA, Lee WRW, Chua Q, Chiou FK, Aw MM, et al. The evidence for probiotics in the treatment of digestive disorders in the pediatric population. J Gastroenterol Hepatol. 2025;40:41. doi:10.1111/jgh.16809
  20. Shah J, Adnan SH, Yousaf MS, Din SJU, Haq MU, et al. A Multi-Hospital Comparative Study on the Efficacy of Probiotics Versus Placebo in Preventing Antibiotic-Associated Diarrhea in Adult Patients. Cureus. 2024;16:e70881. doi:10.7759/cureus.70881
  21. Shawky LM, Abo El Wafa SM, Behery M, Bahr MH, Abu Alnasr MT, et al. Lactobacillus rhamnosus GG and Tannic Acid Synergistically Promote the Gut Barrier Integrity in a Rat Model of Experimental Diarrhea via Selective Immunomodulatory Cytokine Targeting. Mol Nutr Food Res. 2024;68:e2400295. doi:10.1002/mnfr.202400295
  22. Anvarifard P, Anbari M, Ghalichi F, Ghoreishi Z, Zarezadeh M. The effectiveness of probiotics as an adjunct therapy in patients under mechanical ventilation: an umbrella systematic review and meta-analysis. Food Funct. 2024;15:5737. doi:10.1039/d3fo04653b
  23. Alharbi BF, Alateek AA. Investigating the influence of probiotics in preventing Traveler's diarrhea: Meta-analysis based systematic review. Travel Med Infect Dis. 2024;59:102703. doi:10.1016/j.tmaid.2024.102703
  24. Abdulah DM, Sulaiman SJ, Ahmed ZW. Effect of probiotics plus zinc supplementation on clinical outcomes of infants and children with acute infectious diarrhea: a randomized controlled trial. Clin Exp Pediatr. 2024;67:203. doi:10.3345/cep.2023.01340
  25. Waitzberg D, Guarner F, Hojsak I, Ianiro G, Polk DB, et al. Can the Evidence-Based Use of Probiotics (Notably Saccharomyces boulardii CNCM I-745 and Lactobacillus rhamnosus GG) Mitigate the Clinical Effects of Antibiotic-Associated Dysbiosis?. Adv Ther. 2024;41:901. doi:10.1007/s12325-024-02783-3
  26. Saviano A, Petruzziello C, Cancro C, Macerola N, Petti A, et al. The Efficacy of a Mix of Probiotics ( LMG P-27481 and GG ATCC 53103) in Preventing Antibiotic-Associated Diarrhea and Infection in Hospitalized Patients: Single-Center, Open-Label, Randomized Trial. Microorganisms. 2024;12. doi:10.3390/microorganisms12010198
  27. Poeta M, Cioffi V, Tarallo A, Damiano C, Lo Vecchio A, et al. Postbiotic Preparation of against Diarrhea and Oxidative Stress Induced by Spike Protein of SARS-CoV-2 in Human Enterocytes. Antioxidants (Basel). 2023;12. doi:10.3390/antiox12101878
  28. Drozdov VN, Shikh EV, Astapovskii AA, Khalaidzheva KN, Solovieva SA, et al. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea and antibiotic-associated diarrhea]. Vopr Pitan. 2023;92:92. doi:10.33029/0042-8833-2023-92-4-92-103
  29. Mego M, Danis R, Chovanec J, Jurisova S, Bystricky B, et al. Randomized double-blind, placebo-controlled multicenter phase III study of prevention of irinotecan-induced diarrhea by a probiotic mixture containing Bifidobacterium BB-12 LGG in colorectal cancer patients. Front Oncol. 2023;13:1168654. doi:10.3389/fonc.2023.1168654
  30. Yang Q, Hu Z, Lei Y, Li X, Xu C, et al. Overview of systematic reviews of probiotics in the prevention and treatment of antibiotic-associated diarrhea in children. Front Pharmacol. 2023;14:1153070. doi:10.3389/fphar.2023.1153070
  31. Niu H, Zhou X, Liu P, Wu Y, Lyu L, et al. Lactobacillus rhamnosus MN-431 Metabolic Tryptophan Alleviates Complementary Food-Induced Diarrhea through PXR-NF-κB Pathway and AHR-Th17 Cell Response Pathways. Mol Nutr Food Res. 2023;67:e2200530. doi:10.1002/mnfr.202200530
  32. Li J, Li Q, Wu Q, Gao N, Wang Z, et al. Exopolysaccharides of Lactobacillus rhamnosus GG ameliorate Salmonella typhimurium-induced intestinal inflammation via the TLR4/NF-κB/MAPK pathway. J Anim Sci Biotechnol. 2023;14:23. doi:10.1186/s40104-023-00830-7
  33. He Q, Lu S, Wang J, Xu C, Qu W, et al. and Berberine Alleviated Yak Calves' Diarrhea via Accommodating Oxidation Resistance, Inflammatory Factors, and Intestinal Microbiota. Animals (Basel). 2024;14. doi:10.3390/ani14162419
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