' 
SCIENTIFIC SCORE
Possibly Effective
Based on 52 Researches
7.3
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Men's Daily Probiotic BlendLactobacillus acidophilusLactobacillus caseiLactobacillus gasseriLactobacillus plantarumLactobacillus paracaseiLactobacillus brevisLactobacillus bulgaricusLactobacillus rhamnosusLactobacillus salivariusLactobacillus fermentumTotal Lacto Cultures (35 Billion CFU)Bifidobacterium lactisBifidobacterium bifidumBifidobacterium breveBifidobacterium infantisBifidobacterium longumTotal Bifido Cultures (15 Billion CFU)
218 mg
+
Total Probiotic Cultures
50 Billion CFU¹
Organic Prebiotic Fiber BlendOrganic Potato [Resistant Starch] (tuber), Organic Acacia Fiber (A. senegal)
365 mg
+
Top Medical Research Studies
8
Lactobacillus JB-1 reduces anxiety
Continuous Ingestion of JB-1 during Chronic Stress Ensures Neurometabolic and Behavioural Stability in Rats.
Study indicates probiotic benefits
We explored how the treatment with JB-1—a type of probiotic bacteria—affects anxiety during chronic stress in rats. In our study, half of the twenty rats received JB-1 while the other half got a placebo over eight weeks of stress exposure.
The results were telling! Rats on JB-1 showed less anxiety and were more willing to explore their environment compared to the placebo group, which largely avoided exploration. Additionally, measurements of brain metabolites indicated that JB-1 helped maintain stability in brain chemistry, even in stressful conditions.
This suggests that lactobacillus rhamnosus might play a beneficial role in reducing anxiety during prolonged stress.
The results were telling! Rats on JB-1 showed less anxiety and were more willing to explore their environment compared to the placebo group, which largely avoided exploration. Additionally, measurements of brain metabolites indicated that JB-1 helped maintain stability in brain chemistry, even in stressful conditions.
This suggests that lactobacillus rhamnosus might play a beneficial role in reducing anxiety during prolonged stress.
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9
Lactobacillus anxiolytic effects proven
[Antioxidant and anxiolytic effect of and under conditions of normobaric hypoxia with hypercapnia].
High relevance for mental health
We investigated the impact of Lactobacillus acidophilus and Bifidobacterium adolescentis on anxiety levels in rats facing acute hypoxia. In our study, 64 male Wistar rats were divided into four groups for comparison. The results showed that rats receiving probiotics exhibited lower oxidative stress and anxiety levels compared to those who did not. Notably, those treated with probiotics went through behavioral tests indicating increased exploratory behavior and decreased anxiety. Overall, our findings suggest that these probiotics offer both antioxidant and anxiety-reducing effects in stressful conditions.
Read More
8
Probiotics may reduce anxiety
Lactobacillus rhamnosus GG colonization in early life regulates gut-brain axis and relieves anxiety-like behavior in adulthood.
High relevance for mental health research
We examined how colonizing newborn mice with probiotics, specifically Lactobacillus rhamnosus GG (LGG), influences anxiety in adulthood. By administering live LGG during pregnancy and early life, we observed significant changes to the gut microbiome and protective effects on the intestinal barrier. Notably, the adult mice with LGG colonization showed reduced anxiety-like behaviors in tests designed to measure stress responses. This indicates that early life probiotics could play an important role in regulating the gut-brain axis and improving mental health in later life.
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Most Useful Reviews
9.5
Calm and sleep
This probiotic is fantastic! I've used it for about two years, initially to address constipation and withdrawal symptoms from valerian. It significantly calmed my anxiety and improved my sleep, especially when taken with a glass of wine before dinner. It also helped lower my blood pressure, which often spikes in stressful situations. After taking it during a stressful work moment, I felt calm and relieved a headache within hours. I'm thrilled to have found this probiotic!
Read More
6.3
Decreased anxiety
I took this for a year or two, assuming more was better due to its 50 billion CFUs. However, testing revealed my gut diversity was in the bottom 5% because of taking just this probiotic. After switching to custom probiotics from Viome, I've experienced notably less anxiety, even amidst significant work stress. These probiotics might be beneficial for a limited time, but long-term, a variety of options may be preferable.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 52 Researches
7.3
- All Researches
9
Lactobacillus anxiolytic effects proven
[Antioxidant and anxiolytic effect of and under conditions of normobaric hypoxia with hypercapnia].
High relevance for mental health
We investigated the impact of Lactobacillus acidophilus and Bifidobacterium adolescentis on anxiety levels in rats facing acute hypoxia. In our study, 64 male Wistar rats were divided into four groups for comparison. The results showed that rats receiving probiotics exhibited lower oxidative stress and anxiety levels compared to those who did not. Notably, those treated with probiotics went through behavioral tests indicating increased exploratory behavior and decreased anxiety. Overall, our findings suggest that these probiotics offer both antioxidant and anxiety-reducing effects in stressful conditions.
Read More
9
Probiotics impact anxiety in AD
Ameliorative effects of probiotics in AlCl-induced mouse model of Alzheimer's disease.
High relevance in neurodegeneration
We investigated how probiotics, specifically Lactobacillus rhamnosus and Bifidobacterium BB-12, can affect anxiety in a mouse model of Alzheimer’s disease. In our study, we found that mice treated with these probiotics exhibited significantly reduced anxiety-like behaviors compared to those exposed to aluminum chloride alone.
Through various behavioral tests, it was evident that this probiotic combination also improved memory functions. Our results suggest that leveraging the gut-brain axis through these probiotics could offer a promising approach for alleviating anxiety and cognitive deficits in neurodegenerative conditions like Alzheimer's.
Through various behavioral tests, it was evident that this probiotic combination also improved memory functions. Our results suggest that leveraging the gut-brain axis through these probiotics could offer a promising approach for alleviating anxiety and cognitive deficits in neurodegenerative conditions like Alzheimer's.
Read More
9
Probiotic alleviates IBS-D symptoms
A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live CECT 7347 (ES1) and heat-treated CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome.
Highly relevant clinical findings
We conducted a study to assess how well the probiotic CECT 7347 (ES1) and the heat-treated version (HT-ES1) helped alleviate diarrhea-predominant irritable bowel syndrome (IBS-D) symptoms in adults. Over 84 days, participants took either the probiotic, the postbiotic, or a placebo, reporting significant improvement in key measures like symptom severity, quality of life, and even anxiety levels. The results demonstrated a notable reduction in IBS symptoms, making it one of the first trials to show such effectiveness in this area.
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9
Bifidobacterium longum may ease anxiety
Interactions between symptoms and psychological status in irritable bowel syndrome: An exploratory study of the impact of a probiotic combination.
Study shows promising probiotic effects.
We examined the impact of a probiotic blend, Bifidobacterium longum strains 1714® and 35642®, on anxiety and irritable bowel syndrome (IBS) symptoms in patients. Over eight weeks, we observed that the treatment helped restore the stress response and improved IBS symptoms and psychometric scores for anxiety and depression.
Interestingly, the benefits continued after stopping treatment, suggesting a lasting positive effect. The findings indicate that managing stress can significantly influence IBS symptoms and associated mood disturbances.
Interestingly, the benefits continued after stopping treatment, suggesting a lasting positive effect. The findings indicate that managing stress can significantly influence IBS symptoms and associated mood disturbances.
Read More
9
Probiotics reduce anxiety in mice
Ameliorative effects of probiotics in AlCl-induced mouse model of Alzheimer's disease.
Highly relevant to Alzheimer's research
We explored how a combination of two probiotics, Lactobacillus rhamnosus GG and Bifidobacterium BB-12, affects anxiety in a mouse model of Alzheimer's disease. By conducting behavioral tests, we observed that probiotics significantly reduced anxiety-like behavior after exposure to aluminum chloride.
Furthermore, the treatment enhanced both spatial and recognition memory compared to the untreated group. Our findings illustrate that these probiotics can potentially alleviate anxiety and cognitive deficits linked with Alzheimer's disease through their influence on the gut-brain axis.
Furthermore, the treatment enhanced both spatial and recognition memory compared to the untreated group. Our findings illustrate that these probiotics can potentially alleviate anxiety and cognitive deficits linked with Alzheimer's disease through their influence on the gut-brain axis.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Calm and sleep
This probiotic is fantastic! I've used it for about two years, initially to address constipation and withdrawal symptoms from valerian. It significantly calmed my anxiety and improved my sleep, especially when taken with a glass of wine before dinner. It also helped lower my blood pressure, which often spikes in stressful situations. After taking it during a stressful work moment, I felt calm and relieved a headache within hours. I'm thrilled to have found this probiotic!
Read More
6.3
Decreased anxiety
I took this for a year or two, assuming more was better due to its 50 billion CFUs. However, testing revealed my gut diversity was in the bottom 5% because of taking just this probiotic. After switching to custom probiotics from Viome, I've experienced notably less anxiety, even amidst significant work stress. These probiotics might be beneficial for a limited time, but long-term, a variety of options may be preferable.
Read More
