5/14/2025
Last update
5/14/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 41 Researches
7.8
USERS' SCORE
Good
Based on 34 Reviews
8.3
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Men's Daily Probiotic BlendLactobacillus acidophilusLactobacillus caseiLactobacillus gasseriLactobacillus plantarumLactobacillus paracaseiLactobacillus brevisLactobacillus bulgaricusLactobacillus rhamnosusLactobacillus salivariusLactobacillus fermentumTotal Lacto Cultures (35 Billion CFU)Bifidobacterium lactisBifidobacterium bifidumBifidobacterium breveBifidobacterium infantisBifidobacterium longumTotal Bifido Cultures (15 Billion CFU)
218 mg
+
Total Probiotic Cultures
50 Billion CFU¹
Organic Prebiotic Fiber BlendOrganic Potato [Resistant Starch] (tuber), Organic Acacia Fiber (A. senegal)
365 mg
+
Top Medical Research Studies
9
Bifidobacterium lactis alleviates bloating
We conducted a study to see if a fermented dairy product with Bifidobacterium lactis DN-173 010 could help reduce bloating in patients with irritable bowel syndrome (IBS) and constipation. In a controlled trial with 34 participants over four weeks, we found that this probiotic significantly decreased abdominal girth and improved gastrointestinal transit times.
Patients reported feeling less bloated, and symptom severity also decreased. These findings suggest that fostering faster transit times may be an effective method to combat abdominal distension.
Patients reported feeling less bloated, and symptom severity also decreased. These findings suggest that fostering faster transit times may be an effective method to combat abdominal distension.
Read More
9
Lactobacillus improves bloating symptoms
We conducted a double-blind, placebo-controlled trial to assess how Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 affect bloating in patients with functional bowel disorders.
Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.
Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.
Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
Read More
9
Lactobacillus acidophilus reduces bloating
We examined how Lactobacillus acidophilus can help treat bloating in patients with dyspepsia due to imbalances in gut bacteria. In a study involving 30 participants, symptoms such as pain, pressure, and bloating were self-reported while objective measures like bowel movements and weight changes were also tracked.
Those affected by antibiotic-induced dysbiosis experienced rapid relief within days. Improvements were noted in symptoms of maldigestion over a week, and remarkable results were observed in patients with radiation enterocolitis. Overall, this probiotic showed promise for alleviating digestive discomfort without notable side effects.
Those affected by antibiotic-induced dysbiosis experienced rapid relief within days. Improvements were noted in symptoms of maldigestion over a week, and remarkable results were observed in patients with radiation enterocolitis. Overall, this probiotic showed promise for alleviating digestive discomfort without notable side effects.
Read More
Most Useful Reviews
9
Stomach improvement
27 people found this helpful
I bought these probiotics on the advice of my gastroenterologist. The cost is considerable, but it's worth it! They help to improve stomach functioning and eliminate unpleasant symptoms of bloating. I noticed the effect on the first day! One capsule a day is convenient; no refrigeration is needed, so it’s easy to take on trips. This is truly a unique product!
Read More
9
Bloating relief
18 people found this helpful
Super brand! My husband's bloating is gone. I will definitely order again from time to time.
Read More
9
Improves gut health
10 people found this helpful
I was sceptical about probiotics but became a firm believer after trying this one. Since starting it, my gut health has significantly improved; bloating has decreased. These tiny organisms truly make a difference. I highly recommend this probiotic for enhancing gut health and overall wellness; it's been a game changer for me.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 41 Researches
7.8
- All Researches
9
Lactobacillus improves bloating symptoms
We conducted a double-blind, placebo-controlled trial to assess how Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 affect bloating in patients with functional bowel disorders.
Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.
Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.
Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
Read More
9
We conducted a study examining the effects of a novel symbiotic treatment, SCM-III, on patients with irritable bowel syndrome (IBS). Sixty-eight adults were divided into two groups—one received SCM-III and the other a heat-inactivated version, both for 12 weeks.
Our findings showed that most patients reported significant improvements in bloating and abdominal pain compared to a control group. Over 80% felt the treatment was effective, while less than 5% labelled it ineffective.
Overall, this suggests that certain IBS patients could greatly benefit from symbiotic treatments like SCM-III, though it may require a cyclic use for best results.
Our findings showed that most patients reported significant improvements in bloating and abdominal pain compared to a control group. Over 80% felt the treatment was effective, while less than 5% labelled it ineffective.
Overall, this suggests that certain IBS patients could greatly benefit from symbiotic treatments like SCM-III, though it may require a cyclic use for best results.
Read More
9
Lactobacillus acidophilus reduces bloating
We examined how Lactobacillus acidophilus can help treat bloating in patients with dyspepsia due to imbalances in gut bacteria. In a study involving 30 participants, symptoms such as pain, pressure, and bloating were self-reported while objective measures like bowel movements and weight changes were also tracked.
Those affected by antibiotic-induced dysbiosis experienced rapid relief within days. Improvements were noted in symptoms of maldigestion over a week, and remarkable results were observed in patients with radiation enterocolitis. Overall, this probiotic showed promise for alleviating digestive discomfort without notable side effects.
Those affected by antibiotic-induced dysbiosis experienced rapid relief within days. Improvements were noted in symptoms of maldigestion over a week, and remarkable results were observed in patients with radiation enterocolitis. Overall, this probiotic showed promise for alleviating digestive discomfort without notable side effects.
Read More
9
We evaluated the effects of a combined probiotic treatment on food allergies in children aged 4 to 5. In our study, 92 children participated, where one group took probiotics containing Lactobacillus rhamnosus GG for 21 days, while the other group did not.
The children on probiotics experienced significant improvements in skin and gastrointestinal symptoms, including a decrease in bloating. Their IgE levels also dropped notably, suggesting an overall healthier immune response. The control group showed no significant changes.
Overall, lactobacillus rhamnosus proved beneficial for reducing allergy symptoms and improving gut health.
The children on probiotics experienced significant improvements in skin and gastrointestinal symptoms, including a decrease in bloating. Their IgE levels also dropped notably, suggesting an overall healthier immune response. The control group showed no significant changes.
Overall, lactobacillus rhamnosus proved beneficial for reducing allergy symptoms and improving gut health.
Read More
9
We investigated how a combination of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001, along with vitamin B6, affects bloating in patients with irritable bowel syndrome (IBS). In a well-structured crossover trial involving 25 IBS patients, we found that this formula significantly reduced bloating by about 36% compared to a placebo. Additionally, patients experienced reduced abdominal pain and improved gut health. Overall, this treatment shows promise for alleviating IBS symptoms and enhancing gut health.
Read More
User Reviews
USERS' SCORE
Good
Based on 34 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Stomach improvement
27 people found this helpful
I bought these probiotics on the advice of my gastroenterologist. The cost is considerable, but it's worth it! They help to improve stomach functioning and eliminate unpleasant symptoms of bloating. I noticed the effect on the first day! One capsule a day is convenient; no refrigeration is needed, so it’s easy to take on trips. This is truly a unique product!
Read More
9
Bloating relief
18 people found this helpful
Super brand! My husband's bloating is gone. I will definitely order again from time to time.
Read More
9
Improves gut health
10 people found this helpful
I was sceptical about probiotics but became a firm believer after trying this one. Since starting it, my gut health has significantly improved; bloating has decreased. These tiny organisms truly make a difference. I highly recommend this probiotic for enhancing gut health and overall wellness; it's been a game changer for me.
Read More
9
Regular bowel movements
4 people found this helpful
I order these for my husband and father who both had digestive issues that have improved within two to three weeks. I use the female version myself occasionally. Initially, it caused some bloating, but that subsided, and I've noticed significant improvements: no bloating, more regularity, and no acid reflux. Well-packaged with no delivery issues.
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9
Gut health improvement
3 people found this helpful
These probiotics (50 billion CFU) work well. I gave them to a friend, who says his stomach and intestinal function has improved. After recovering from COVID, he reports that the bloating has gone.
Read More
Frequently Asked Questions
9
Quick relief from bloating
11 people found this helpful
A very good combination of prebiotics and probiotics. They increase beneficial lactic acid bacteria in the gut and inhibit harmful flora, restoring intestinal balance. This brand produces excellent products, and these symbiotics are no exception. They worked faster than others for me, alleviating stomach issues and bloating by the first day. Suitable for antibiotic use as well, taken an hour after.
9
Immediate relief
It saved me from flatulence! After trying many probiotics, this one significantly relieved my intestinal discomfort and bloating within just three to four days of use. It worked almost immediately. I felt relieved when I restocked it after being out of stock for a long time.
9
Regular bowel movements
4 people found this helpful
I order these for my husband and father who both had digestive issues that have improved within two to three weeks. I use the female version myself occasionally. Initially, it caused some bloating, but that subsided, and I've noticed significant improvements: no bloating, more regularity, and no acid reflux. Well-packaged with no delivery issues.
9
Stomach improvement
27 people found this helpful
I bought these probiotics on the advice of my gastroenterologist. The cost is considerable, but it's worth it! They help to improve stomach functioning and eliminate unpleasant symptoms of bloating. I noticed the effect on the first day! One capsule a day is convenient; no refrigeration is needed, so it’s easy to take on trips. This is truly a unique product!
9
Bloating eliminated
1 people found this helpful
My husband has consistently provided good feedback! Probiotics are friendly bacteria that help protect against infections. He takes one capsule daily, and the bloating has subsided. His bowel movements are now normal, and gas production has ceased.
9
Enhanced digestion
1 people found this helpful
I ordered these probiotics for my boyfriend. After much consideration and numerous positive reviews, I was hopeful. His stomach used to swell after meals, but since taking these, digestion has improved, his stomach no longer bloats, and his intestines seem to process food better. I’m quite pleased with the value!
9
Overall health improved
2 people found this helpful
Life-changing! After trying numerous brands and strains of probiotics, I can happily say I’ve finally found one that helps with my bloating due to food sensitivities like gluten, beans, and cabbage. My overall digestive health has improved significantly in about a month. I'm over the moon!
9
Relieved symptoms
1 people found this helpful
Excellent! This is very useful for the digestive system, effectively alleviating symptoms of Irritable Bowel Syndrome, such as bloating, gas, and stomachache.
7
We explored the effectiveness of various probiotic strains and combinations in treating bloating related to irritable bowel syndrome (IBS). This comprehensive analysis included data from 9,253 participants across 81 studies.
While some probiotics showed promise in alleviating abdominal bloating, the results indicated that only specific strains were effective. Among them, noteworthy probiotics included MTCC 5856 and CNCM I-3856.
Overall, the findings highlight that while probiotics can help some IBS symptoms, not all are effective for bloating, calling for more research to better understand these treatments.
While some probiotics showed promise in alleviating abdominal bloating, the results indicated that only specific strains were effective. Among them, noteworthy probiotics included MTCC 5856 and CNCM I-3856.
Overall, the findings highlight that while probiotics can help some IBS symptoms, not all are effective for bloating, calling for more research to better understand these treatments.
8
Lactobacillus reduces bloating effectively
We investigated how Lactobacillus acidophilus affects bloating in patients following Roux-en-Y gastric bypass surgery. In a randomized, double-blind, placebo-controlled trial, patients received either probiotic supplements or placebo for 90 days. While both groups experienced similar rates of small intestine bacterial overgrowth (SIBO), those in the probiotic group reported significantly less bloating. They also noted increased abdominal pain initially, but that decreased over time, along with more episodes of soft stools and nausea. Hence, probiotics effectively reduce bloating without impacting SIBO levels.
8
We examined how multispecies probiotics, including Lactobacillus acidophilus, affect bloating in individuals with irritable bowel syndrome (IBS). In a randomized, double-blind trial, 49 IBS patients were split into two groups: one received probiotics and the other a placebo for four weeks.
By the end of the study, we found that 68% of the probiotics group reported significant relief from IBS symptoms, including reduced bloating. Fecal analysis indicated beneficial changes in gut bacteria from the probiotics, highlighting their potential role in improving IBS symptoms.
By the end of the study, we found that 68% of the probiotics group reported significant relief from IBS symptoms, including reduced bloating. Fecal analysis indicated beneficial changes in gut bacteria from the probiotics, highlighting their potential role in improving IBS symptoms.
7
This randomized, double-blind study tested the effects of a synbiotic supplement featuring Lactobacillus acidophilus on gut health in 36 healthy adults. Over six weeks, participants taking the synbiotic reported improved gastrointestinal well-being and bowel habits compared to those who received a placebo.
While there were notable benefits in symptoms like bloating and digestive discomfort, immunological parameters did not show significant changes. This suggests that while the synbiotic could enhance gut comfort, its effects on inflammation levels appear limited.
While there were notable benefits in symptoms like bloating and digestive discomfort, immunological parameters did not show significant changes. This suggests that while the synbiotic could enhance gut comfort, its effects on inflammation levels appear limited.
9
Bifidobacterium lactis alleviates bloating
We conducted a study to see if a fermented dairy product with Bifidobacterium lactis DN-173 010 could help reduce bloating in patients with irritable bowel syndrome (IBS) and constipation. In a controlled trial with 34 participants over four weeks, we found that this probiotic significantly decreased abdominal girth and improved gastrointestinal transit times.
Patients reported feeling less bloated, and symptom severity also decreased. These findings suggest that fostering faster transit times may be an effective method to combat abdominal distension.
Patients reported feeling less bloated, and symptom severity also decreased. These findings suggest that fostering faster transit times may be an effective method to combat abdominal distension.
7
We assessed the effectiveness of a 2-strain mixture of Lactobacillus acidophilus in easing symptoms of irritable bowel syndrome (IBS), including bloating. In a well-structured trial involving 80 patients, we monitored their response to probiotic or placebo capsules over eight weeks. While abdominal pain and symptoms improved overall, it was noted that the probiotics significantly reduced flatus and composite scores. However, no major differences in bloating scores were observed between the groups. Thus, while there are benefits, they don’t specifically highlight improvements in bloating.
9
Lactobacillus improves bloating symptoms
We conducted a double-blind, placebo-controlled trial to assess how Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 affect bloating in patients with functional bowel disorders.
Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.
Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.
Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
References
- Xie P, Luo M, Deng X, Fan J, Xiong L. Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis. Nutrients. 2023;15. 10.3390/nu15173856
- Wagner NRF, Ramos MRZ, de Oliveira Carlos L, da Cruz MRR, Taconeli CA, et al. Effects of Probiotics Supplementation on Gastrointestinal Symptoms and SIBO after Roux-en-Y Gastric Bypass: a Prospective, Randomized, Double-Blind, Placebo-Controlled Trial. Obes Surg. 2021;31:143. 10.1007/s11695-020-04900-x
- Maixent JM, Pons O, Sennoune SR, Sadrin S. Clinical effects of Lactobacillus strains as probiotics in the treatment of irritable bowel syndrome. Results from the LAPIBSS trial: Future objectives. Cell Mol Biol (Noisy-le-grand). 2020;66:211.
- Sadrin S, Sennoune S, Gout B, Marque S, Moreau J, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis. 2020;52:534. 10.1016/j.dld.2019.12.009
- Wang MC, Zaydi AI, Lin WH, Lin JS, Liong MT, et al. Putative Probiotic Strains Isolated from Kefir Improve Gastrointestinal Health Parameters in Adults: a Randomized, Single-Blind, Placebo-Controlled Study. Probiotics Antimicrob Proteins. 2020;12:840. 10.1007/s12602-019-09615-9
- Airaksinen K, Yeung N, Lyra A, Lahtinen SJ, Huttunen T, et al. The effect of a probiotic blend on gastrointestinal symptoms in constipated patients: a double blind, randomised, placebo controlled 2-week trial. Benef Microbes. 2019;10:617. 10.3920/BM2018.0163
- Georgescu D, Ancusa OE, Georgescu LA, Ionita I, Reisz D. Nonmotor gastrointestinal disorders in older patients with Parkinson's disease: is there hope?. Clin Interv Aging. 2016;11:1601.
- Ringel-Kulka T, Goldsmith JR, Carroll IM, Barros SP, Palsson O, et al. Lactobacillus acidophilus NCFM affects colonic mucosal opioid receptor expression in patients with functional abdominal pain - a randomised clinical study. Aliment Pharmacol Ther. 2014;40:200. 10.1111/apt.12800
- Yoon JS, Sohn W, Lee OY, Lee SP, Lee KN, et al. Effect of multispecies probiotics on irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Gastroenterol Hepatol. 2014;29:52. 10.1111/jgh.12322
- Andresen V, Layer P, Menge D, Keller J. [Efficacy of freeze-dried Lactobacilli in functional diarrhoe: a pilot study]. Dtsch Med Wochenschr. 2012;137:1792. 10.1055/s-0032-1305295
- Ringel-Kulka T, Palsson OS, Maier D, Carroll I, Galanko JA, et al. Probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 versus placebo for the symptoms of bloating in patients with functional bowel disorders: a double-blind study. J Clin Gastroenterol. 2011;45:518. 10.1097/MCG.0b013e31820ca4d6
- Nova E, Viadel B, Wärnberg J, Carreres JE, Marcos A. Beneficial effects of a synbiotic supplement on self-perceived gastrointestinal well-being and immunoinflammatory status of healthy adults. J Med Food. 2011;14:79. 10.1089/jmf.2008.0328
- Tsuchiya J, Barreto R, Okura R, Kawakita S, Fesce E, et al. Single-blind follow-up study on the effectiveness of a symbiotic preparation in irritable bowel syndrome. Chin J Dig Dis. 2004;5:169.
- Molin G. Probiotics in foods not containing milk or milk constituents, with special reference to Lactobacillus plantarum 299v. Am J Clin Nutr. 2001;73:380S. 10.1093/ajcn/73.2.380s
- Gaón D, Doweck Y, Gómez Zavaglia A, Ruiz Holgado A, Oliver G. [Lactose digestion by milk fermented with Lactobacillus acidophilus and Lactobacillus casei of human origin]. Medicina (B Aires). 1995;55:237.
- Kocián J. [Lactobacilli in the treatment of dyspepsia due to dysmicrobia of various causes]. Vnitr Lek. 1994;40:79.
- Kwon H, Nam EH, Kim H, Jo H, Bang WY, et al. Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial. Sci Rep. 2024;14:22384. 10.1038/s41598-024-72887-x
- Vorobieva OA, Shih EV, Drozdov VN, Shikh NV. [The results of the use of a combined probiotic ( and spp. ВB-12) in children with gastrointestinal and skin manifestations of food allergy]. Vopr Pitan. 2023;92:79. 10.33029/0042-8833-2023-92-3-79-86
- Bonfrate L, Di Palo DM, Celano G, Albert A, Vitellio P, et al. Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients. Eur J Clin Invest. 2020;50:e13201. 10.1111/eci.13201
- Lai HH, Chiu CH, Kong MS, Chang CJ, Chen CC. Probiotic : Effective for Managing Childhood Diarrhea by Altering Gut Microbiota and Attenuating Fecal Inflammatory Markers. Nutrients. 2019;11. 10.3390/nu11051150
- Vitellio P, Celano G, Bonfrate L, Gobbetti M, Portincasa P, et al. Effects of and on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study. Nutrients. 2019;11. 10.3390/nu11040886
- Hayes SR, Vargas AJ. Probiotics for the Prevention of Pediatric Antibiotic-Associated Diarrhea. Explore (NY). 2016;12:463. 10.1016/j.explore.2016.08.015
- Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, et al. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev. 2015. 10.1002/14651858.CD004827.pub4
- Hauser G, Salkic N, Vukelic K, JajacKnez A, Stimac D. Probiotics for standard triple Helicobacter pylori eradication: a randomized, double-blind, placebo-controlled trial. Medicine (Baltimore). 2015;94:e685. 10.1097/MD.0000000000000685
- Ruiz-Sánchez C, Escudero-López B, Fernández-Pachón MS. Evaluation of the efficacy of probiotics as treatment in irritable bowel syndrome. Endocrinol Diabetes Nutr (Engl Ed). 2024;71:19. 10.1016/j.endien.2024.01.003
- Guglielmetti S, Mora D, Gschwender M, Popp K. Randomised clinical trial: Bifidobacterium bifidum MIMBb75 significantly alleviates irritable bowel syndrome and improves quality of life--a double-blind, placebo-controlled study. Aliment Pharmacol Ther. 2011;33:1123. 10.1111/j.1365-2036.2011.04633.x
- Tanashat M, Abuelazm M, Abouzid M, Al-Ajlouni YA, Ramadan A, et al. Efficacy of probiotics regimens for Helicobacter pylori eradication: A systematic review, pairwise, and network meta-analysis of randomized controlled trials. Clin Nutr ESPEN. 2025;65:424. 10.1016/j.clnesp.2024.11.016
- Srivastava S, Basak U, Naghibi M, Vijayakumar V, Parihar R, et al. A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live CECT 7347 (ES1) and heat-treated CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome. Gut Microbes. 2024;16:2338322. 10.1080/19490976.2024.2338322
- Lenoir M, Wienke J, Fardao-Beyler F, Roese N. An 8-Week Course of Bifidobacterium longum 35624 Is Associated with a Reduction in the Symptoms of Irritable Bowel Syndrome. Probiotics Antimicrob Proteins. 2025;17:315. 10.1007/s12602-023-10151-w
- Miyoshi M, Kadoguchi H, Usami M, Hori Y. Synbiotics Improved Stool Form via Changes in the Microbiota and Short-Chain Fatty Acids in Hemodialysis Patients. Kobe J Med Sci. 2021;67:E112.
- Zhang C, Jiang J, Tian F, Zhao J, Zhang H, et al. Meta-analysis of randomized controlled trials of the effects of probiotics on functional constipation in adults. Clin Nutr. 2020;39:2960. 10.1016/j.clnu.2020.01.005
- Chen JC, Lee WJ, Tsou JJ, Liu TP, Tsai PL. Effect of probiotics on postoperative quality of gastric bypass surgeries: a prospective randomized trial. Surg Obes Relat Dis. 2016;12:57. 10.1016/j.soard.2015.07.010
- Colecchia A, Vestito A, La Rocca A, Pasqui F, Nikiforaki A, et al. Effect of a symbiotic preparation on the clinical manifestations of irritable bowel syndrome, constipation-variant. Results of an open, uncontrolled multicenter study. Minerva Gastroenterol Dietol. 2006;52:349.
- Lan W, Yang H, Zhong Z, Luo C, Huang Q, et al. subsp. LPL-RH improves postoperative gastrointestinal symptoms and nutrition indexes by regulating the gut microbiota in patients with valvular heart disease: a randomized controlled trial. Food Funct. 2024;15:7605. 10.1039/d4fo01471e
- Şahin K, Şahintürk Y, Köker G, Özçelik Köker G, Bostan F, et al. Metformin with Versus without Concomitant Probiotic Therapy in Newly Diagnosed Patients with Type 2 Diabetes or Prediabetes: A Comparative Analysis in Relation to Glycemic Control, Gastrointestinal Side Effects, and Treatment Compliance. Turk J Gastroenterol. 2022;33:925. 10.5152/tjg.2022.211063
- Shin CM, Choi YJ, Lee DH, Moon JS, Kim TY, et al. Validity and safety of ID-JPL934 in lower gastrointestinal symptom improvement. Sci Rep. 2021;11:13046. 10.1038/s41598-021-92007-3
- Marteau P, Le Nevé B, Quinquis L, Pichon C, Whorwell PJ, et al. Consumption of a Fermented Milk Product Containing CNCM I-2494 in Women Complaining of Minor Digestive Symptoms: Rapid Response Which Is Independent of Dietary Fibre Intake or Physical Activity. Nutrients. 2019;11. 10.3390/nu11010092
- Baştürk A, Artan R, Yılmaz A. Efficacy of synbiotic, probiotic, and prebiotic treatments for irritable bowel syndrome in children: A randomized controlled trial. Turk J Gastroenterol. 2016;27:439. 10.5152/tjg.2016.16301
- Del Piano M, Carmagnola S, Anderloni A, Andorno S, Ballarè M, et al. The use of probiotics in healthy volunteers with evacuation disorders and hard stools: a double-blind, randomized, placebo-controlled study. J Clin Gastroenterol. 2010;44 Suppl 1:S30. 10.1097/MCG.0b013e3181ee31c3
- Agrawal A, Houghton LA, Morris J, Reilly B, Guyonnet D, et al. Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173 010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation. Aliment Pharmacol Ther. 2009;29:104. 10.1111/j.1365-2036.2008.03853.x
- Guyonnet D, Chassany O, Ducrotte P, Picard C, Mouret M, et al. Effect of a fermented milk containing Bifidobacterium animalis DN-173 010 on the health-related quality of life and symptoms in irritable bowel syndrome in adults in primary care: a multicentre, randomized, double-blind, controlled trial. Aliment Pharmacol Ther. 2007;26:475.
