Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.4
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Men's Daily Probiotic BlendLactobacillus acidophilusLactobacillus caseiLactobacillus gasseriLactobacillus plantarumLactobacillus paracaseiLactobacillus brevisLactobacillus bulgaricusLactobacillus rhamnosusLactobacillus salivariusLactobacillus fermentumTotal Lacto Cultures (35 Billion CFU)Bifidobacterium lactisBifidobacterium bifidumBifidobacterium breveBifidobacterium infantisBifidobacterium longumTotal Bifido Cultures (15 Billion CFU)
218 mg
+
Total Probiotic Cultures
50 Billion CFU¹
Organic Prebiotic Fiber BlendOrganic Potato [Resistant Starch] (tuber), Organic Acacia Fiber (A. senegal)
365 mg
+
Top Medical Research Studies
9
We examined a promising new probiotic preparation designed to break down gluten and assist people with celiac disease. Our study included a randomized double-blind placebo-controlled trial with 70 volunteers over a 42-day period, where participants consumed increasing amounts of gluten following a gluten-free diet.
Those who took the probiotics showed significantly lower levels of residual gluten in their feces compared to the placebo group. Additionally, the probiotics appeared to enhance gut microbiota health, promoting beneficial microbial communities. However, despite these findings, we must proceed cautiously, as the overall impact on celiac disease management remains to be fully determined.
Those who took the probiotics showed significantly lower levels of residual gluten in their feces compared to the placebo group. Additionally, the probiotics appeared to enhance gut microbiota health, promoting beneficial microbial communities. However, despite these findings, we must proceed cautiously, as the overall impact on celiac disease management remains to be fully determined.
Read More
9
We explored the effects of Bacillus subtilis LZU-GM, a probiotic isolated from traditional Pakistani sourdough, on gluten-related issues in celiac disease. Remarkably, this strain degraded 73.7% of gluten in lab tests and showed threefold more gluten breakdown in mice models compared to untreated groups.
However, while it improved gut health by promoting beneficial bacteria, and reducing inflammatory markers, it didn't eliminate the formation of antibodies associated with gluten sensitivity. Thus, we found that although LZU-GM has potential, it may not be a complete solution for managing celiac disease.
However, while it improved gut health by promoting beneficial bacteria, and reducing inflammatory markers, it didn't eliminate the formation of antibodies associated with gluten sensitivity. Thus, we found that although LZU-GM has potential, it may not be a complete solution for managing celiac disease.
Read More
8
Probiotic shows potential in celiac
We explored whether Acetobacter ghanensis could reduce gliadin-induced toxicity in intestinal cells from celiac disease patients. Using a cell culture model, we found that gliadin disrupts the intestinal barrier and raises inflammatory markers like IL-6 and TNFα. However, when A. ghanensis was introduced, it showed potential in restoring barrier function and digesting gluten peptides. This study highlights A. ghanensis as a promising candidate for improving gut health in those affected by celiac disease, although more research is needed to confirm these findings.
Read More
Most Useful Reviews
9
Exceptional digestion support
Perfect! My husband began taking Dr. Formulated Probiotics for Men by Garden of Life, and the outcomes have been outstanding. He struggled with constipation and bloating, but after using this probiotic, he experienced a significant improvement. His digestion is much smoother, and he feels less discomfort from gas. The high CFU count (50 billion per serving) and diverse probiotic strains tailored for men's gut health really make this supplement stand out. It’s also gluten-free, dairy-free, and soy-free, making it suitable for those with dietary restrictions. Overall, if you're searching for a high-quality probiotic to enhance digestion and reduce bloating, I highly recommend this one!
Read More
7.5
Convenient travel solution
Perfect for travel! It needs no refrigeration, making it ideal for trips. My husband is gluten sensitive, and dining out can lead to unforeseen challenges. This product aids his digestion remarkably.
Read More
7.5
Improved digestive health
2 people found this helpful
Life changing! I have tested numerous brands and various strains of probiotics over the years. I'm pleased to say I've finally discovered something that alleviates my bloating from food sensitivities, including gluten, beans, cabbage, broccoli, and other gassy foods. My overall digestive health has enhanced notably within a month. I'm so happy!!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.4
- All Researches
9
We examined a promising new probiotic preparation designed to break down gluten and assist people with celiac disease. Our study included a randomized double-blind placebo-controlled trial with 70 volunteers over a 42-day period, where participants consumed increasing amounts of gluten following a gluten-free diet.
Those who took the probiotics showed significantly lower levels of residual gluten in their feces compared to the placebo group. Additionally, the probiotics appeared to enhance gut microbiota health, promoting beneficial microbial communities. However, despite these findings, we must proceed cautiously, as the overall impact on celiac disease management remains to be fully determined.
Those who took the probiotics showed significantly lower levels of residual gluten in their feces compared to the placebo group. Additionally, the probiotics appeared to enhance gut microbiota health, promoting beneficial microbial communities. However, despite these findings, we must proceed cautiously, as the overall impact on celiac disease management remains to be fully determined.
Read More
9
We explored the effects of Bacillus subtilis LZU-GM, a probiotic isolated from traditional Pakistani sourdough, on gluten-related issues in celiac disease. Remarkably, this strain degraded 73.7% of gluten in lab tests and showed threefold more gluten breakdown in mice models compared to untreated groups.
However, while it improved gut health by promoting beneficial bacteria, and reducing inflammatory markers, it didn't eliminate the formation of antibodies associated with gluten sensitivity. Thus, we found that although LZU-GM has potential, it may not be a complete solution for managing celiac disease.
However, while it improved gut health by promoting beneficial bacteria, and reducing inflammatory markers, it didn't eliminate the formation of antibodies associated with gluten sensitivity. Thus, we found that although LZU-GM has potential, it may not be a complete solution for managing celiac disease.
Read More
8
Brazilian cassava cultivars enhance probiotics
We examined the prebiotic effects of Brazilian cassava cultivars on celiac individuals. Focusing on two selected varieties, OUR and UPI, we observed their ability to promote growth in beneficial probiotic strains. This was evident in the increased population of helpful bacteria compared to established prebiotics like fructooligosaccharides. Our findings indicate that these cassava cultivars can positively influence the gut microbiota in celiacs, suggesting their potential use as prebiotic ingredients in functional foods and supplements.
Read More
8
Probiotic shows potential in celiac
We explored whether Acetobacter ghanensis could reduce gliadin-induced toxicity in intestinal cells from celiac disease patients. Using a cell culture model, we found that gliadin disrupts the intestinal barrier and raises inflammatory markers like IL-6 and TNFα. However, when A. ghanensis was introduced, it showed potential in restoring barrier function and digesting gluten peptides. This study highlights A. ghanensis as a promising candidate for improving gut health in those affected by celiac disease, although more research is needed to confirm these findings.
Read More
8
We investigated the effectiveness of the NLS super strain (NLS-SS) probiotic on alleviating gastrointestinal symptoms in patients with celiac disease (CD) who have been on a gluten-free diet for at least two years. Through a carefully designed randomized, double-blind, placebo-controlled trial, we found that those with severe symptoms experienced improved relief from their CD symptoms after taking NLS-SS.
This probiotic also influenced gut microbiota diversity in these patients without significant side effects. While promising, more extensive studies are necessary to fully validate these results.
This probiotic also influenced gut microbiota diversity in these patients without significant side effects. While promising, more extensive studies are necessary to fully validate these results.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Exceptional digestion support
Perfect! My husband began taking Dr. Formulated Probiotics for Men by Garden of Life, and the outcomes have been outstanding. He struggled with constipation and bloating, but after using this probiotic, he experienced a significant improvement. His digestion is much smoother, and he feels less discomfort from gas. The high CFU count (50 billion per serving) and diverse probiotic strains tailored for men's gut health really make this supplement stand out. It’s also gluten-free, dairy-free, and soy-free, making it suitable for those with dietary restrictions. Overall, if you're searching for a high-quality probiotic to enhance digestion and reduce bloating, I highly recommend this one!
Read More
7.5
Convenient travel solution
Perfect for travel! It needs no refrigeration, making it ideal for trips. My husband is gluten sensitive, and dining out can lead to unforeseen challenges. This product aids his digestion remarkably.
Read More
7.5
Improved digestive health
2 people found this helpful
Life changing! I have tested numerous brands and various strains of probiotics over the years. I'm pleased to say I've finally discovered something that alleviates my bloating from food sensitivities, including gluten, beans, cabbage, broccoli, and other gassy foods. My overall digestive health has enhanced notably within a month. I'm so happy!!
Read More
Frequently Asked Questions
7.5
Improved digestive health
2 people found this helpful
Life changing! I have tested numerous brands and various strains of probiotics over the years. I'm pleased to say I've finally discovered something that alleviates my bloating from food sensitivities, including gluten, beans, cabbage, broccoli, and other gassy foods. My overall digestive health has enhanced notably within a month. I'm so happy!!
9
Exceptional digestion support
Perfect! My husband began taking Dr. Formulated Probiotics for Men by Garden of Life, and the outcomes have been outstanding. He struggled with constipation and bloating, but after using this probiotic, he experienced a significant improvement. His digestion is much smoother, and he feels less discomfort from gas. The high CFU count (50 billion per serving) and diverse probiotic strains tailored for men's gut health really make this supplement stand out. It’s also gluten-free, dairy-free, and soy-free, making it suitable for those with dietary restrictions. Overall, if you're searching for a high-quality probiotic to enhance digestion and reduce bloating, I highly recommend this one!
7.5
Convenient travel solution
Perfect for travel! It needs no refrigeration, making it ideal for trips. My husband is gluten sensitive, and dining out can lead to unforeseen challenges. This product aids his digestion remarkably.
9
We explored the effects of Bacillus subtilis LZU-GM, a probiotic isolated from traditional Pakistani sourdough, on gluten-related issues in celiac disease. Remarkably, this strain degraded 73.7% of gluten in lab tests and showed threefold more gluten breakdown in mice models compared to untreated groups.
However, while it improved gut health by promoting beneficial bacteria, and reducing inflammatory markers, it didn't eliminate the formation of antibodies associated with gluten sensitivity. Thus, we found that although LZU-GM has potential, it may not be a complete solution for managing celiac disease.
However, while it improved gut health by promoting beneficial bacteria, and reducing inflammatory markers, it didn't eliminate the formation of antibodies associated with gluten sensitivity. Thus, we found that although LZU-GM has potential, it may not be a complete solution for managing celiac disease.
9
We examined a promising new probiotic preparation designed to break down gluten and assist people with celiac disease. Our study included a randomized double-blind placebo-controlled trial with 70 volunteers over a 42-day period, where participants consumed increasing amounts of gluten following a gluten-free diet.
Those who took the probiotics showed significantly lower levels of residual gluten in their feces compared to the placebo group. Additionally, the probiotics appeared to enhance gut microbiota health, promoting beneficial microbial communities. However, despite these findings, we must proceed cautiously, as the overall impact on celiac disease management remains to be fully determined.
Those who took the probiotics showed significantly lower levels of residual gluten in their feces compared to the placebo group. Additionally, the probiotics appeared to enhance gut microbiota health, promoting beneficial microbial communities. However, despite these findings, we must proceed cautiously, as the overall impact on celiac disease management remains to be fully determined.
7
Probiotics show potential benefits
We assessed the potential benefits of probiotics for managing gastrointestinal symptoms in patients with celiac disease (CD). After analyzing data from 14 clinical trials, we found that probiotics may help reduce GI symptoms, especially in those with severe cases, and promote a better immune response.
The analysis also indicated that probiotics increased levels of beneficial gut bacteria, such as Bifidobacterium and Lactobacillus, without raising adverse effects compared to placebos.
However, the evidence remains inconclusive, highlighting the need for further quality studies to determine the best probiotic combinations.
The analysis also indicated that probiotics increased levels of beneficial gut bacteria, such as Bifidobacterium and Lactobacillus, without raising adverse effects compared to placebos.
However, the evidence remains inconclusive, highlighting the need for further quality studies to determine the best probiotic combinations.
7
We examined the impact of probiotics on patients with celiac disease, whose only established treatment is a strict gluten-free diet. Even with adherence, many struggle with gut microbiota restoration, which is vital for nutrient absorption. Some studies suggest probiotics might help by enhancing gut health and reducing inflammation caused by gluten. Other dietary aids, like prebiotics, also show promise in promoting beneficial bacteria. Nonetheless, evidence supporting routine use of these supplements remains insufficient for clinical practice.
References
- Mafaldo ÍM, Araújo LM, Cabral L, Barão CE, Noronha MF, et al. Cassava (Manihot esculenta) Brazilian cultivars have different chemical compositions, present prebiotic potential, and beneficial effects on the colonic microbiota of celiac individuals. Food Res Int. 2024;195:114909. doi:10.1016/j.foodres.2024.114909
- Nikoloudaki O, Celano G, Polo A, Cappello C, Granehäll L, et al. Novel probiotic preparation with gluten-degrading activity and potential modulatory effects on the gut microbiota. Microbiol Spectr. 2024;12:e0352423. doi:10.1128/spectrum.03524-23
- Khan A, Li S, Han H, Jin WL, Ling Z, et al. A gluten degrading probiotic Bacillus subtilis LZU-GM relieve adverse effect of gluten additive food and balances gut microbiota in mice. Food Res Int. 2023;170:112960. doi:10.1016/j.foodres.2023.112960
- Mozafarybazargany M, Khonsari M, Sokoty L, Ejtahed HS, Qorbani M. The effects of probiotics on gastrointestinal symptoms and microbiota in patients with celiac disease: a systematic review and meta-analysis on clinical trials. Clin Exp Med. 2023;23:2773. doi:10.1007/s10238-022-00987-x
- Doguer C, Akalan H, Tokatlı Demirok N, Erdal B, Mete R, et al. Protective effects of Acetobacter ghanensis against gliadin toxicity in intestinal epithelial cells with immunoregulatory and gluten-digestive properties. Eur J Nutr. 2023;62:605. doi:10.1007/s00394-022-03015-6
- Andriulli A, Bevilacqua A, Palmieri O, Latiano A, Fontana R, et al. Healthy and pro-inflammatory gut ecology plays a crucial role in the digestion and tolerance of a novel Gluten Friendly™ bread in celiac subjects: a randomized, double blind, placebo control study. Food Funct. 2022;13:1299. doi:10.1039/d1fo00490e
- Jedwab CF, Roston BCMB, Toge ABFS, Echeverria IF, Tavares GOG, et al. The role of probiotics in the immune response and intestinal microbiota of children with celiac disease: a systematic review. Rev Paul Pediatr. 2021;40:e2020447. doi:10.1590/1984-0462/2022/40/2020447
- Wei G, Darwish G, Oppenheim FG, Schuppan D, Helmerhorst EJ. Commensal Bacterium Degrades and Detoxifies Gluten via a Highly Effective Subtilisin Enzyme. Nutrients. 2020;12. doi:10.3390/nu12123724
- Smecuol E, Constante M, Temprano MP, Costa AF, Moreno ML, et al. Effect of NLS super strain in symptomatic coeliac disease patients on long-term gluten-free diet - an exploratory study. Benef Microbes. 2020;11:527. doi:10.3920/BM2020.0016
- Marasco G, Cirota GG, Rossini B, Lungaro L, Di Biase AR, et al. Probiotics, Prebiotics and Other Dietary Supplements for Gut Microbiota Modulation in Celiac Disease Patients. Nutrients. 2020;12. doi:10.3390/nu12092674
- Seiler CL, Kiflen M, Stefanolo JP, Bai JC, Bercik P, et al. Probiotics for Celiac Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Am J Gastroenterol. 2020;115:1584. doi:10.14309/ajg.0000000000000749
- Pecora F, Persico F, Gismondi P, Fornaroli F, Iuliano S, et al. Gut Microbiota in Celiac Disease: Is There Any Role for Probiotics?. Front Immunol. 2020;11:957. doi:10.3389/fimmu.2020.00957
- de Almeida NEC, Esteves FG, Dos Santos-Pinto JRA, Peres de Paula C, da Cunha AF, et al. Digestion of Intact Gluten Proteins by Species: Reduction of Cytotoxicity and Proinflammatory Responses. J Agric Food Chem. 2020;68:4485. doi:10.1021/acs.jafc.0c01421
