Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 41 Researches
7.8
USERS' SCORE
Moderately Good
Based on 29 Reviews
7.2
Supplement Facts
Serving Size:  2 Capsules
Amount Per Serving
%DV
Mood Probiotic BlendLactobacillus acidophilusLactobacillus plantarumLactobacillus helveticus R0052Lactobacillus paracaseiLactobacillus caseiLactobacillus brevisLactobacillus rhamnosusLactobacillus bulgaricusLactobacillus gasseriLactobacillus salivariusTotal Lacto Cultures (45 Billion CFU)Bifidobacterium lactisBifidobacterium longum R0175Bifidobacterium bifidumBifidobacterium breveBifidobacterium infantisBifidobacterium longumTotal Bifido Cultures (5 Billion CFU)
200 mg
+
Total Probiotic Cultures
50 Billion CFU¹
 
Stress Support BlendOrganic Ashwagandha (root), Blueberry (fruit)
350 mg
+
Organic Prebiotic Fiber BlendOrganic Potato [Resistant Starch] (tuber), Organic Acacia Fiber (A. senegal)
675 mg
+

Top Medical Research Studies

9
Bifidobacterium lactis alleviates bloating
We conducted a study to see if a fermented dairy product with Bifidobacterium lactis DN-173 010 could help reduce bloating in patients with irritable bowel syndrome (IBS) and constipation. In a controlled trial with 34 participants over four weeks, we found that this probiotic significantly decreased abdominal girth and improved gastrointestinal transit times.

Patients reported feeling less bloated, and symptom severity also decreased. These findings suggest that fostering faster transit times may be an effective method to combat abdominal distension.
Read More
9
Lactobacillus improves bloating symptoms
We conducted a double-blind, placebo-controlled trial to assess how Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 affect bloating in patients with functional bowel disorders.

Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.

Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
Read More
9
Lactobacillus acidophilus reduces bloating
We examined how Lactobacillus acidophilus can help treat bloating in patients with dyspepsia due to imbalances in gut bacteria. In a study involving 30 participants, symptoms such as pain, pressure, and bloating were self-reported while objective measures like bowel movements and weight changes were also tracked.

Those affected by antibiotic-induced dysbiosis experienced rapid relief within days. Improvements were noted in symptoms of maldigestion over a week, and remarkable results were observed in patients with radiation enterocolitis. Overall, this probiotic showed promise for alleviating digestive discomfort without notable side effects.
Read More

Most Useful Reviews

2
Caused constipation
6 people found this helpful
I had high hopes for this product, believing its ingredients could help with anxiety and depression. Unfortunately, I experienced severe constipation and bloating. After stopping the product, relief came within 24 hours. Perhaps it just didn't suit my individual system, but I hope it works better for others.
Read More
0
Prolonged bloating
6 people found this helpful
After taking just one tablet, I have been bloated for five days. Every meal has become torturous. I attempted to take another tablet, but it didn’t alleviate the issue. It seems best to stop taking it altogether and allow my microbiome to recover. I was surprised, given its positive reviews, to have such adverse effects.
Read More
9
Removes bloating
2 people found this helpful
This product excels in addressing digestion problems, effectively removes bloating, is easily absorbed, and does not lead to constipation. The taste is also acceptable.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 41 Researches
7.8
  • All Researches
9
Lactobacillus improves bloating symptoms
We conducted a double-blind, placebo-controlled trial to assess how Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 affect bloating in patients with functional bowel disorders.

Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.

Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
Read More
9
SCM-III improves IBS symptoms
We conducted a study examining the effects of a novel symbiotic treatment, SCM-III, on patients with irritable bowel syndrome (IBS). Sixty-eight adults were divided into two groups—one received SCM-III and the other a heat-inactivated version, both for 12 weeks.

Our findings showed that most patients reported significant improvements in bloating and abdominal pain compared to a control group. Over 80% felt the treatment was effective, while less than 5% labelled it ineffective.

Overall, this suggests that certain IBS patients could greatly benefit from symbiotic treatments like SCM-III, though it may require a cyclic use for best results.
Read More
9
Lactobacillus acidophilus reduces bloating
We examined how Lactobacillus acidophilus can help treat bloating in patients with dyspepsia due to imbalances in gut bacteria. In a study involving 30 participants, symptoms such as pain, pressure, and bloating were self-reported while objective measures like bowel movements and weight changes were also tracked.

Those affected by antibiotic-induced dysbiosis experienced rapid relief within days. Improvements were noted in symptoms of maldigestion over a week, and remarkable results were observed in patients with radiation enterocolitis. Overall, this probiotic showed promise for alleviating digestive discomfort without notable side effects.
Read More
9
Probiotics improve allergy symptoms
We evaluated the effects of a combined probiotic treatment on food allergies in children aged 4 to 5. In our study, 92 children participated, where one group took probiotics containing Lactobacillus rhamnosus GG for 21 days, while the other group did not.

The children on probiotics experienced significant improvements in skin and gastrointestinal symptoms, including a decrease in bloating. Their IgE levels also dropped notably, suggesting an overall healthier immune response. The control group showed no significant changes.

Overall, lactobacillus rhamnosus proved beneficial for reducing allergy symptoms and improving gut health.
Read More
We investigated how a combination of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001, along with vitamin B6, affects bloating in patients with irritable bowel syndrome (IBS). In a well-structured crossover trial involving 25 IBS patients, we found that this formula significantly reduced bloating by about 36% compared to a placebo. Additionally, patients experienced reduced abdominal pain and improved gut health. Overall, this treatment shows promise for alleviating IBS symptoms and enhancing gut health.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 29 Reviews
7.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
2
Caused constipation
6 people found this helpful
I had high hopes for this product, believing its ingredients could help with anxiety and depression. Unfortunately, I experienced severe constipation and bloating. After stopping the product, relief came within 24 hours. Perhaps it just didn't suit my individual system, but I hope it works better for others.
Read More
0
Prolonged bloating
6 people found this helpful
After taking just one tablet, I have been bloated for five days. Every meal has become torturous. I attempted to take another tablet, but it didn’t alleviate the issue. It seems best to stop taking it altogether and allow my microbiome to recover. I was surprised, given its positive reviews, to have such adverse effects.
Read More
9
Removes bloating
2 people found this helpful
This product excels in addressing digestion problems, effectively removes bloating, is easily absorbed, and does not lead to constipation. The taste is also acceptable.
Read More
9
Healthy gut effects
1 people found this helpful
Realising that a healthy gut supports a healthy brain, I began taking this probiotic over a year ago. The frequent bloating and constipation I used to have have vanished, replaced by a more balanced microbiome. I believe my system is now better at absorbing nutrients.
Read More
9
Digestive improvement
1 people found this helpful
The advantage of the Garden of Life Dr. Formulated Mood+ probiotics is the blend of 16 clinically studied strains along with Ashwagandha and Blueberry, designed to balance digestion. I take 2 capsules each night, and within a week, I've noticed a marked improvement; my digestion has enhanced, with no bloating or constipation, and my sleep has also improved. A great supplement, though not inexpensive! I recommend it.
Read More

Frequently Asked Questions

9
Digestive improvement
1 people found this helpful
The advantage of the Garden of Life Dr. Formulated Mood+ probiotics is the blend of 16 clinically studied strains along with Ashwagandha and Blueberry, designed to balance digestion. I take 2 capsules each night, and within a week, I've noticed a marked improvement; my digestion has enhanced, with no bloating or constipation, and my sleep has also improved. A great supplement, though not inexpensive! I recommend it.
9
Eliminated bloating
The components of this probiotic are fantastic, although the packaging lasts only a month. After a week of use, my bloating and intestinal issues vanished, and I’ve stopped vomiting, which was a previous issue. I take two capsules with dinner. While I can’t comment on mood quite yet, I highly recommend it and plan to purchase more.
7.5
Effective but anxiety
2 people found this helpful
I took this daily for two weeks, which somewhat improved my gut health as I stopped bloating after meals and my mood brightened. However, this was marred by extreme bloating later on, accompanied by significant anxiety, including palpitations and insomnia. I have stopped the product, and the side effects are subsiding, suggesting it may have been too much probiotic for my system.
0
Prolonged bloating
6 people found this helpful
After taking just one tablet, I have been bloated for five days. Every meal has become torturous. I attempted to take another tablet, but it didn’t alleviate the issue. It seems best to stop taking it altogether and allow my microbiome to recover. I was surprised, given its positive reviews, to have such adverse effects.
9
Healthy gut effects
1 people found this helpful
Realising that a healthy gut supports a healthy brain, I began taking this probiotic over a year ago. The frequent bloating and constipation I used to have have vanished, replaced by a more balanced microbiome. I believe my system is now better at absorbing nutrients.
9
Removes bloating
2 people found this helpful
This product excels in addressing digestion problems, effectively removes bloating, is easily absorbed, and does not lead to constipation. The taste is also acceptable.
4
Lactobacillus acidophilus reduces flatus
We used a rigorous clinical trial to investigate the impact of Lactobacillus acidophilus on bloating and other IBS symptoms. Involving 80 patients diagnosed with IBS, we followed a double-blind, placebo-controlled approach over eight weeks.

While the treatment did not significantly relieve abdominal pain, we noted a marked decrease in flatus and overall symptom scores at eight weeks. This suggests that while lactobacillus acidophilus may not help with all IBS symptoms, it could be beneficial for reducing bloating-related discomfort.
We investigated how a combination of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001, along with vitamin B6, affects bloating in patients with irritable bowel syndrome (IBS). In a well-structured crossover trial involving 25 IBS patients, we found that this formula significantly reduced bloating by about 36% compared to a placebo. Additionally, patients experienced reduced abdominal pain and improved gut health. Overall, this treatment shows promise for alleviating IBS symptoms and enhancing gut health.
7
Probiotics show mixed efficacy
We explored the effectiveness of various probiotic strains and combinations in treating bloating related to irritable bowel syndrome (IBS). This comprehensive analysis included data from 9,253 participants across 81 studies.

While some probiotics showed promise in alleviating abdominal bloating, the results indicated that only specific strains were effective. Among them, noteworthy probiotics included MTCC 5856 and CNCM I-3856.

Overall, the findings highlight that while probiotics can help some IBS symptoms, not all are effective for bloating, calling for more research to better understand these treatments.
8
Probiotics alleviate bloating in IBS
We examined how multispecies probiotics, including Lactobacillus acidophilus, affect bloating in individuals with irritable bowel syndrome (IBS). In a randomized, double-blind trial, 49 IBS patients were split into two groups: one received probiotics and the other a placebo for four weeks.

By the end of the study, we found that 68% of the probiotics group reported significant relief from IBS symptoms, including reduced bloating. Fecal analysis indicated beneficial changes in gut bacteria from the probiotics, highlighting their potential role in improving IBS symptoms.
We examined how probiotics, specifically Bifidobacterium bifidum, can help ease bloating and other symptoms of irritable bowel syndrome (IBS). Our study reviewed 18 articles, indicating that one dose of Bifidobacterium bifidum (1 × 10 CFU/day) over four weeks showed the most promise in alleviating gut-related issues.

Combining Bifidobacterium with two Lactobacillus strains and one Streptococcus strain boosted effectiveness even further. However, further clinical trials are necessary to fully confirm these findings and understand the best treatment options.
9
Lactobacillus improves bloating symptoms
We conducted a double-blind, placebo-controlled trial to assess how Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 affect bloating in patients with functional bowel disorders.

Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.

Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
9
Bifidobacterium bifidum improves bloating
Our study focused on how Bifidobacterium bifidum MIMBb75 affects bloating in patients with irritable bowel syndrome (IBS). We conducted a double-blind trial with 122 participants, half receiving MIMBb75 and half a placebo over four weeks.

The results showed that MIMBb75 significantly reduced bloating and other IBS symptoms, improving overall quality of life. About 47% of participants taking MIMBb75 reported adequate relief, compared to only 11% in the placebo group.

This makes MIMBb75 a promising option for those struggling with IBS and bloating.

References

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  2. Wagner NRF, Ramos MRZ, de Oliveira Carlos L, da Cruz MRR, Taconeli CA, et al. Effects of Probiotics Supplementation on Gastrointestinal Symptoms and SIBO after Roux-en-Y Gastric Bypass: a Prospective, Randomized, Double-Blind, Placebo-Controlled Trial. Obes Surg. 2021;31:143. doi:10.1007/s11695-020-04900-x
  3. Maixent JM, Pons O, Sennoune SR, Sadrin S. Clinical effects of Lactobacillus strains as probiotics in the treatment of irritable bowel syndrome. Results from the LAPIBSS trial: Future objectives. Cell Mol Biol (Noisy-le-grand). 2020;66:211.
  4. Sadrin S, Sennoune S, Gout B, Marque S, Moreau J, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis. 2020;52:534. doi:10.1016/j.dld.2019.12.009
  5. Wang MC, Zaydi AI, Lin WH, Lin JS, Liong MT, et al. Putative Probiotic Strains Isolated from Kefir Improve Gastrointestinal Health Parameters in Adults: a Randomized, Single-Blind, Placebo-Controlled Study. Probiotics Antimicrob Proteins. 2020;12:840. doi:10.1007/s12602-019-09615-9
  6. Airaksinen K, Yeung N, Lyra A, Lahtinen SJ, Huttunen T, et al. The effect of a probiotic blend on gastrointestinal symptoms in constipated patients: a double blind, randomised, placebo controlled 2-week trial. Benef Microbes. 2019;10:617. doi:10.3920/BM2018.0163
  7. Georgescu D, Ancusa OE, Georgescu LA, Ionita I, Reisz D. Nonmotor gastrointestinal disorders in older patients with Parkinson's disease: is there hope?. Clin Interv Aging. 2016;11:1601.
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  9. Yoon JS, Sohn W, Lee OY, Lee SP, Lee KN, et al. Effect of multispecies probiotics on irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Gastroenterol Hepatol. 2014;29:52. doi:10.1111/jgh.12322
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  12. Nova E, Viadel B, Wärnberg J, Carreres JE, Marcos A. Beneficial effects of a synbiotic supplement on self-perceived gastrointestinal well-being and immunoinflammatory status of healthy adults. J Med Food. 2011;14:79. doi:10.1089/jmf.2008.0328
  13. Tsuchiya J, Barreto R, Okura R, Kawakita S, Fesce E, et al. Single-blind follow-up study on the effectiveness of a symbiotic preparation in irritable bowel syndrome. Chin J Dig Dis. 2004;5:169.
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  18. Vorobieva OA, Shih EV, Drozdov VN, Shikh NV. [The results of the use of a combined probiotic ( and spp. ВB-12) in children with gastrointestinal and skin manifestations of food allergy]. Vopr Pitan. 2023;92:79. doi:10.33029/0042-8833-2023-92-3-79-86
  19. Bonfrate L, Di Palo DM, Celano G, Albert A, Vitellio P, et al. Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients. Eur J Clin Invest. 2020;50:e13201. doi:10.1111/eci.13201
  20. Lai HH, Chiu CH, Kong MS, Chang CJ, Chen CC. Probiotic : Effective for Managing Childhood Diarrhea by Altering Gut Microbiota and Attenuating Fecal Inflammatory Markers. Nutrients. 2019;11. doi:10.3390/nu11051150
  21. Vitellio P, Celano G, Bonfrate L, Gobbetti M, Portincasa P, et al. Effects of and on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study. Nutrients. 2019;11. doi:10.3390/nu11040886
  22. Hayes SR, Vargas AJ. Probiotics for the Prevention of Pediatric Antibiotic-Associated Diarrhea. Explore (NY). 2016;12:463. doi:10.1016/j.explore.2016.08.015
  23. Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, et al. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev. 2015. doi:10.1002/14651858.CD004827.pub4
  24. Hauser G, Salkic N, Vukelic K, JajacKnez A, Stimac D. Probiotics for standard triple Helicobacter pylori eradication: a randomized, double-blind, placebo-controlled trial. Medicine (Baltimore). 2015;94:e685. doi:10.1097/MD.0000000000000685
  25. Ruiz-Sánchez C, Escudero-López B, Fernández-Pachón MS. Evaluation of the efficacy of probiotics as treatment in irritable bowel syndrome. Endocrinol Diabetes Nutr (Engl Ed). 2024;71:19. doi:10.1016/j.endien.2024.01.003
  26. Guglielmetti S, Mora D, Gschwender M, Popp K. Randomised clinical trial: Bifidobacterium bifidum MIMBb75 significantly alleviates irritable bowel syndrome and improves quality of life--a double-blind, placebo-controlled study. Aliment Pharmacol Ther. 2011;33:1123. doi:10.1111/j.1365-2036.2011.04633.x
  27. Tanashat M, Abuelazm M, Abouzid M, Al-Ajlouni YA, Ramadan A, et al. Efficacy of probiotics regimens for Helicobacter pylori eradication: A systematic review, pairwise, and network meta-analysis of randomized controlled trials. Clin Nutr ESPEN. 2025;65:424. doi:10.1016/j.clnesp.2024.11.016
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  29. Lenoir M, Wienke J, Fardao-Beyler F, Roese N. An 8-Week Course of Bifidobacterium longum 35624 Is Associated with a Reduction in the Symptoms of Irritable Bowel Syndrome. Probiotics Antimicrob Proteins. 2025;17:315. doi:10.1007/s12602-023-10151-w
  30. Miyoshi M, Kadoguchi H, Usami M, Hori Y. Synbiotics Improved Stool Form via Changes in the Microbiota and Short-Chain Fatty Acids in Hemodialysis Patients. Kobe J Med Sci. 2021;67:E112.
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  34. Lan W, Yang H, Zhong Z, Luo C, Huang Q, et al. subsp. LPL-RH improves postoperative gastrointestinal symptoms and nutrition indexes by regulating the gut microbiota in patients with valvular heart disease: a randomized controlled trial. Food Funct. 2024;15:7605. doi:10.1039/d4fo01471e
  35. Şahin K, Şahintürk Y, Köker G, Özçelik Köker G, Bostan F, et al. Metformin with Versus without Concomitant Probiotic Therapy in Newly Diagnosed Patients with Type 2 Diabetes or Prediabetes: A Comparative Analysis in Relation to Glycemic Control, Gastrointestinal Side Effects, and Treatment Compliance. Turk J Gastroenterol. 2022;33:925. doi:10.5152/tjg.2022.211063
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  37. Marteau P, Le Nevé B, Quinquis L, Pichon C, Whorwell PJ, et al. Consumption of a Fermented Milk Product Containing CNCM I-2494 in Women Complaining of Minor Digestive Symptoms: Rapid Response Which Is Independent of Dietary Fibre Intake or Physical Activity. Nutrients. 2019;11. doi:10.3390/nu11010092
  38. Baştürk A, Artan R, Yılmaz A. Efficacy of synbiotic, probiotic, and prebiotic treatments for irritable bowel syndrome in children: A randomized controlled trial. Turk J Gastroenterol. 2016;27:439. doi:10.5152/tjg.2016.16301
  39. Del Piano M, Carmagnola S, Anderloni A, Andorno S, Ballarè M, et al. The use of probiotics in healthy volunteers with evacuation disorders and hard stools: a double-blind, randomized, placebo-controlled study. J Clin Gastroenterol. 2010;44 Suppl 1:S30. doi:10.1097/MCG.0b013e3181ee31c3
  40. Agrawal A, Houghton LA, Morris J, Reilly B, Guyonnet D, et al. Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173 010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation. Aliment Pharmacol Ther. 2009;29:104. doi:10.1111/j.1365-2036.2008.03853.x
  41. Guyonnet D, Chassany O, Ducrotte P, Picard C, Mouret M, et al. Effect of a fermented milk containing Bifidobacterium animalis DN-173 010 on the health-related quality of life and symptoms in irritable bowel syndrome in adults in primary care: a multicentre, randomized, double-blind, controlled trial. Aliment Pharmacol Ther. 2007;26:475.
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