Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 29 Researches
8.1
USERS' SCORE
Good
Based on 3 Reviews
8.2
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Mood Probiotic BlendLactobacillus acidophilusLactobacillus plantarumLactobacillus helveticus R0052Lactobacillus paracaseiLactobacillus caseiLactobacillus brevisLactobacillus rhamnosusLactobacillus bulgaricusLactobacillus gasseriLactobacillus salivariusTotal Lacto Cultures (45 Billion CFU)Bifidobacterium lactisBifidobacterium longum R0175Bifidobacterium bifidumBifidobacterium breveBifidobacterium infantisBifidobacterium longumTotal Bifido Cultures (5 Billion CFU)
200 mg
+
Total Probiotic Cultures
50 Billion CFU¹
Stress Support BlendOrganic Ashwagandha (root), Blueberry (fruit)
350 mg
+
Organic Prebiotic Fiber BlendOrganic Potato [Resistant Starch] (tuber), Organic Acacia Fiber (A. senegal)
675 mg
+
Top Medical Research Studies
9
We explored how Lactobacillus rhamnosus BFE5264 affects cholesterol levels using a mouse model on a high-cholesterol diet. This study revealed that this strain significantly reduced serum cholesterol levels while also altering the gut microbiome and increasing beneficial short-chain fatty acids. The findings suggest that L. rhamnosus could regulate cholesterol metabolism in the liver, showing effects similar to those of statin medications. These results highlight the potential of probiotics as a novel approach for managing cholesterol levels.
Read More
9
DHA lowers cholesterol; boosts metabolism
We aimed to investigate how docosahexaenoic acid (DHA) impacts cholesterol levels and brain glucose metabolism. In our study, we focused on aged SAMP8 mice, dividing them into two groups: a control group and one receiving DHA supplementation.
Our results revealed encouraging changes; the group that received DHA showed a decrease in total cholesterol and low-density lipoprotein cholesterol, while high-density lipoprotein cholesterol levels increased. More importantly, we observed improvements in glucose metabolism in various brain regions, including the cortex and hippocampus.
These findings suggest that DHA may help lower harmful cholesterol levels and enhance brain function by regulating specific cholesterol compounds like 27-hydroxycholesterol, which are linked to glucose metabolism. Overall, our study highlights DHA's potential in supporting heart and brain health through cholesterol management.
Our results revealed encouraging changes; the group that received DHA showed a decrease in total cholesterol and low-density lipoprotein cholesterol, while high-density lipoprotein cholesterol levels increased. More importantly, we observed improvements in glucose metabolism in various brain regions, including the cortex and hippocampus.
These findings suggest that DHA may help lower harmful cholesterol levels and enhance brain function by regulating specific cholesterol compounds like 27-hydroxycholesterol, which are linked to glucose metabolism. Overall, our study highlights DHA's potential in supporting heart and brain health through cholesterol management.
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7
We investigated the impact of two probiotic strains, Lactobacillus rhamnosus BFE5264 and Lactiplantibacillus plantarum NR74, on high cholesterol levels in a murine model. The results indicated that these probiotics help reduce cholesterol absorption in the intestines and support liver metabolism.
Specifically, L. rhamnosus was particularly effective in boosting cholesterol processing in the liver. However, as this study focused on animal models, more research is needed to confirm these findings in humans.
Overall, these probiotics show promise for managing diet-related hypercholesterolemia.
Specifically, L. rhamnosus was particularly effective in boosting cholesterol processing in the liver. However, as this study focused on animal models, more research is needed to confirm these findings in humans.
Overall, these probiotics show promise for managing diet-related hypercholesterolemia.
Read More
Most Useful Reviews
9
Resolved gut issues
This is a great product; my gut issues were resolved after about two weeks of use. I would highly recommend these probiotics.
Read More
6
Improved digestion
1 people found this helpful
The quality and ingredients are commendable. I've noticed a benefit, especially in digestion during the first week, which was quite impressive. There was no constipation, but the packaging is small, and the price feels high.
Read More
7.5
Convenient probiotics
These probiotics are of very high quality, better than others I’ve tried. They don’t need refrigeration, and I noticed a significant improvement in my digestion shortly after starting them. I take them in the morning before meals to ensure they work effectively in my intestines.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 29 Researches
8.1
- All Researches
9
We investigated the effects of Lactobacillus rhamnosus on high cholesterol and blood sugar levels in diabetic rats.
By using yogurt fermented with this probiotic, we noticed significant reductions in blood glucose and an increase in healthy cholesterol levels.
Within just four days of consuming the yogurt, notable changes in liver and kidney enzymes were observed, alongside improvements in lipid profiles.
While promising, further research is needed to confirm these benefits in humans.
By using yogurt fermented with this probiotic, we noticed significant reductions in blood glucose and an increase in healthy cholesterol levels.
Within just four days of consuming the yogurt, notable changes in liver and kidney enzymes were observed, alongside improvements in lipid profiles.
While promising, further research is needed to confirm these benefits in humans.
Read More
9
We investigated the cholesterol-lowering effects of two specific probiotic strains, FM9 and Y57, using a high-fat diet model in male Wistar rats. Over 30 days, these strains demonstrated a significant ability to improve blood lipid profiles.
Notably, FM9 and Y57 reduced serum cholesterol levels by 9% and 8%, respectively, while also improving "good" HDL cholesterol levels more than the statin treatment.
These results suggest that probiotics like FM9 and Y57 may offer a natural alternative to conventional medications for managing cholesterol, with the potential for anti-obesity benefits too, though clinical trials are needed to confirm these effects in humans.
Notably, FM9 and Y57 reduced serum cholesterol levels by 9% and 8%, respectively, while also improving "good" HDL cholesterol levels more than the statin treatment.
These results suggest that probiotics like FM9 and Y57 may offer a natural alternative to conventional medications for managing cholesterol, with the potential for anti-obesity benefits too, though clinical trials are needed to confirm these effects in humans.
Read More
9
We explored how two specific probiotic strains, Lactobacillus johnsonni 3121 and Lactobacillus rhamnosus 86, impact high cholesterol conditions linked to obesity. In our study using obese mice on a high-fat diet, we observed that daily doses of these probiotics over 12 weeks led to significant improvements in cholesterol levels.
Notably, both strains reduced lipid accumulation and influenced the genes involved in fat cell development. Additionally, they helped restore the balance of gut bacteria affected by obesity. These findings suggest that these probiotics could be valuable in managing high cholesterol and obesity-related health issues.
Notably, both strains reduced lipid accumulation and influenced the genes involved in fat cell development. Additionally, they helped restore the balance of gut bacteria affected by obesity. These findings suggest that these probiotics could be valuable in managing high cholesterol and obesity-related health issues.
Read More
9
Lactobacillus rhamnosus shows cholesterol-lowering effects
We examined the potential of Lactobacillus rhamnosus and other strains to lower cholesterol levels. Through in vitro testing, we observed impressive cholesterol reduction rates, achieving up to 91% decrease after 120 hours. When we moved to in vivo studies using rats fed fermented milk, we noted reductions in overall cholesterol, LDL, and triglycerides, while also enhancing HDL levels. Importantly, these probiotic strains demonstrated safety and effectiveness in their role as natural options for managing high cholesterol.
Read More
9
We explored how Lactobacillus rhamnosus BFE5264 affects cholesterol levels using a mouse model on a high-cholesterol diet. This study revealed that this strain significantly reduced serum cholesterol levels while also altering the gut microbiome and increasing beneficial short-chain fatty acids. The findings suggest that L. rhamnosus could regulate cholesterol metabolism in the liver, showing effects similar to those of statin medications. These results highlight the potential of probiotics as a novel approach for managing cholesterol levels.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Resolved gut issues
This is a great product; my gut issues were resolved after about two weeks of use. I would highly recommend these probiotics.
Read More
6
Improved digestion
1 people found this helpful
The quality and ingredients are commendable. I've noticed a benefit, especially in digestion during the first week, which was quite impressive. There was no constipation, but the packaging is small, and the price feels high.
Read More
7.5
Convenient probiotics
These probiotics are of very high quality, better than others I’ve tried. They don’t need refrigeration, and I noticed a significant improvement in my digestion shortly after starting them. I take them in the morning before meals to ensure they work effectively in my intestines.
Read More
Frequently Asked Questions
9
Resolved gut issues
This is a great product; my gut issues were resolved after about two weeks of use. I would highly recommend these probiotics.
6
Improved digestion
1 people found this helpful
The quality and ingredients are commendable. I've noticed a benefit, especially in digestion during the first week, which was quite impressive. There was no constipation, but the packaging is small, and the price feels high.
7.5
Convenient probiotics
These probiotics are of very high quality, better than others I’ve tried. They don’t need refrigeration, and I noticed a significant improvement in my digestion shortly after starting them. I take them in the morning before meals to ensure they work effectively in my intestines.
7
We explored how a new combination of Lactobacillus rhamnosus and xylo-oligosaccharides could help lower cholesterol levels. The study tested this synbiotic approach by simulating cholesterol-lowering effects in a lab setting.
Results suggested that it may work by down-regulating certain genes involved in cholesterol absorption and promoting a healthier gut microbiome. While promising, further research is needed to confirm its effectiveness in real-world conditions among people.
Results suggested that it may work by down-regulating certain genes involved in cholesterol absorption and promoting a healthier gut microbiome. While promising, further research is needed to confirm its effectiveness in real-world conditions among people.
8
We dove into how lactobacillus rhamnosus, along with other lactic acid bacteria, can help reduce cholesterol levels. Our research showed that these probiotics not only lowered cholesterol in a lab setting but also did so effectively in living organisms.
Specifically, lactobacillus rhamnosus cut cholesterol levels by up to 40%. Importantly, these strains were safe and non-toxic, making them promising candidates for managing high cholesterol. Overall, this study suggests a potential natural approach to tackle hypercholesterolemia.
Specifically, lactobacillus rhamnosus cut cholesterol levels by up to 40%. Importantly, these strains were safe and non-toxic, making them promising candidates for managing high cholesterol. Overall, this study suggests a potential natural approach to tackle hypercholesterolemia.
8
We explored the effects of docosahexaenoic acid (DHA) on cholesterol levels, based on a systematic review of randomized controlled trials. This research focused on the potential cardiovascular benefits of DHA, particularly its impact on high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol levels.
According to the findings, DHA is effective in raising HDL cholesterol, which is considered protective against heart disease. In fact, DHA appears to have a greater impact, compared to its counterpart, eicosapentaenoic acid (EPA). Interestingly, while DHA may also elevate LDL cholesterol levels, it simultaneously increases the size of LDL particles, making them less harmful.
Furthermore, DHA was found to contribute to lowering heart rate and blood pressure, which are key factors for cardiovascular health. The research highlighted that both EPA and DHA positively influence platelet function and reduce oxidative stress and inflammation, further supporting heart health.
Although the results show that DHA has a series of beneficial effects, the information on its role in cholesterol management needed to be more definitive. More high-quality research is warranted to establish the comprehensive impact of DHA on cholesterol and other cardiovascular risk factors.
According to the findings, DHA is effective in raising HDL cholesterol, which is considered protective against heart disease. In fact, DHA appears to have a greater impact, compared to its counterpart, eicosapentaenoic acid (EPA). Interestingly, while DHA may also elevate LDL cholesterol levels, it simultaneously increases the size of LDL particles, making them less harmful.
Furthermore, DHA was found to contribute to lowering heart rate and blood pressure, which are key factors for cardiovascular health. The research highlighted that both EPA and DHA positively influence platelet function and reduce oxidative stress and inflammation, further supporting heart health.
Although the results show that DHA has a series of beneficial effects, the information on its role in cholesterol management needed to be more definitive. More high-quality research is warranted to establish the comprehensive impact of DHA on cholesterol and other cardiovascular risk factors.
7
Dietary Fish Oil and Cholesterol
We explored the potential benefits of incorporating a diet high in docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) from locally sourced fish waste into the diets of adult Beagle dogs. Through a crossover study involving two diets—one made primarily of imported shrimp hydrolysate and salmon oil (control) and another consisting of locally produced fish hydrolysate and oil (experimental)—we aimed to evaluate how these diets impact cholesterol levels, inflammation markers, and even the health of gut bacteria.
Our findings revealed that the experimental diet led to a decrease in plasmatic triglycerides and hinted at a reduction in total cholesterol, which could suggest an improvement in cholesterol management. However, while we observed changes in triglyceride levels, we found no significant effects on systemic inflammatory markers or on the overall serum cholesterol levels in the dogs. Moreover, the diets did not show a notable impact on blood pressure or heart rate.
Despite the promising nutrient profile of the experimental diet, the lack of significant changes in some key health markers indicates that simply increasing DHA and EPA through this dietary approach might not yield immediate or profound improvements in high cholesterol. This underscores the complexity of dietary impacts on health, which deserve further investigation, especially in terms of long-term effectiveness and changes in gut microbiome health.
Overall, our study suggests that while locally sourced fish products may replace traditional sources without negative effects, the benefits on cholesterol management remain to be fully understood.
Our findings revealed that the experimental diet led to a decrease in plasmatic triglycerides and hinted at a reduction in total cholesterol, which could suggest an improvement in cholesterol management. However, while we observed changes in triglyceride levels, we found no significant effects on systemic inflammatory markers or on the overall serum cholesterol levels in the dogs. Moreover, the diets did not show a notable impact on blood pressure or heart rate.
Despite the promising nutrient profile of the experimental diet, the lack of significant changes in some key health markers indicates that simply increasing DHA and EPA through this dietary approach might not yield immediate or profound improvements in high cholesterol. This underscores the complexity of dietary impacts on health, which deserve further investigation, especially in terms of long-term effectiveness and changes in gut microbiome health.
Overall, our study suggests that while locally sourced fish products may replace traditional sources without negative effects, the benefits on cholesterol management remain to be fully understood.
References
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