Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 110 Researches
7.9
USERS' SCORE
Good
Based on 7 Reviews
8.7
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Replenish BlendBifidobacterium lactis BL818, Lactobacillus acidophilus (SD-5221),Lactobacillus paracasei (SD-5218), Bifidobacterium lactis (SD-5220),Raw Whole Food Probiotic Blend: Bulgarian Yogurt (milk)Concentrate, ^Eastern European Wild Kefir Culture containingBifidobacterium lactis, Bifidobacterium longum, Lactobacillusacidophilus, Lactobacillus brevis, Lactobacillus bulgaricus,Lactobacillus casei, Lactobacillus fermentum, Lactobacillushelveticus, Lactobacillus kefiranofaciens, Lactobacillus kefirgranum,Lactobacillus rhamnosus, Lactococcus lactis, Lactococcus cremoris,Streptococcus thermophilus, Lactobacillus kefir, Lactobacillusparakefir, Lactobacillus plantarum, Lactococcus lactis biovardiacetylactis, Leuconostoc lactis, Leuconostoc mesenteroides,Leuconostoc cremoris, Leuconostoc dextranicum, Kluyveromycesmarxianus, Brettanomyces anomalus, Debaryomyces hansenii,Saccharomyces unisporus, Saccharomyces turicensis,Saccharomyces cerevisiae, Saccharomyces exiguus,Torulaspora delbrueckii
100 Billion CFU¹
+
Protein-Digesting Enzyme BlendProtease, Acid Protease, Protease S
50 mg
+
Eastern European Raw Fruit and Veggie BlendRed Bell Pepper (Fruit), Green Pea (Seed), Carrot (Root), Plum (Fruit), Cherry (Fruit), Strawberry (Fruit), Raspberry (Fruit)
45 mg
+
Top Medical Research Studies
9.5
Bifidobacterium lactis reduced diarrhea duration
We explored the impact of Bifidobacterium animalis subsp. lactis BLa80 on diarrhea in young children through a well-structured, randomized, double-blinded, placebo-controlled study.
Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.
Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.
This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.
Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.
This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
Read More
9.5
We explored the effectiveness of a live recombinant Lactococcus lactis vaccine designed to combat enterotoxigenic Escherichia coli, a major cause of diarrhea. The study involved administering the vaccine to mice, who then showed strong immune responses, such as increased antibody production and T cell activation.
After being challenged with ETEC, these mice exhibited complete protection from the disease. This suggests that the Lactococcus lactis vaccine could be a promising oral vaccine candidate against E. coli-related diarrhea.
After being challenged with ETEC, these mice exhibited complete protection from the disease. This suggests that the Lactococcus lactis vaccine could be a promising oral vaccine candidate against E. coli-related diarrhea.
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9
We evaluated the effectiveness of Bifidobacterium lactis XLTG11 in treating acute watery diarrhea in children through a rigorous randomized, double-blind, placebo-controlled trial.
Children who received the probiotic alongside their conventional treatment had significantly shorter diarrhea durations and hospital stays compared to those who only got standard care. Additionally, those taking Bifidobacterium showed better improvement rates and healthier gut microbiomes after treatment.
Overall, this study suggests that Bifidobacterium lactis can be a beneficial adjunct therapy for children suffering from diarrhea.
Children who received the probiotic alongside their conventional treatment had significantly shorter diarrhea durations and hospital stays compared to those who only got standard care. Additionally, those taking Bifidobacterium showed better improvement rates and healthier gut microbiomes after treatment.
Overall, this study suggests that Bifidobacterium lactis can be a beneficial adjunct therapy for children suffering from diarrhea.
Read More
Most Useful Reviews
10
Life-changing product
This product has transformed my life. For a year, digestive issues plagued me, and my food intolerances kept escalating. I lost over 10 lbs and was apprehensive about eating anything. Previous probiotics exacerbated my issues. After starting Garden of Life Raw Probiotics, my stomach problems vanished in two days; I even managed to eat trigger foods without any issue. I now feel like a different person and never want to be without it.
Read More
10
Daily normalcy
Over the years, I've been plagued with persistent diarrhea, trying numerous diets and medications. At my wits' end, I started taking this product daily, and it has changed my life! Now, I only go to the toilet 1 to 2 times a day and, importantly, there's no diarrhoea. I can't believe the difference it has made; I’ll definitely buy it again and recommend it!
Read More
10
Normal bowel function
After being on IV antibiotics due to a dog bite, I continued experiencing terrible diarrhea despite taking multiple probiotics and kefir daily. My doctor suggested this brand. Within two days of switching, my situation normalised. My husband also suffered from severe diarrhea but after taking my probiotic, he has returned to normal as well. It's effective but quite expensive.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 110 Researches
7.9
- All Researches
9.5
We explored the impact of Lactobacillus acidophilus and L. plantarum on patients suffering from diarrhea-predominant irritable bowel syndrome (IBS-D). In a randomized, single-blinded clinical trial of 100 patients, some received standard IBS treatment alone while others added probiotics to their therapy.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
Read More
9.5
We explored the impact of Lactobacillus acidophilus and L. plantarum on patients suffering from diarrhea-predominant irritable bowel syndrome (IBS-D). In a randomized, single-blinded clinical trial of 100 patients, some received standard IBS treatment alone while others added probiotics to their therapy.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
Read More
9.5
Lactobacillus shows promise for diarrhea
We aimed to explore how Lactobacillus acidophilus can help relieve diarrhea symptoms associated with irritable bowel syndrome (IBS) and antibiotic-associated diarrhea (AAD).
In a study with 54 patients, those taking the probiotic Neobiotic Lactobalance® for 21 days saw significant reductions in diarrhea severity and abdominal pain, with scores dropping impressively on the Gastrointestinal Symptom Rating Scale.
Fecal analysis indicated improved intestinal health, highlighting Lactobacillus's potential benefits for those struggling with these conditions.
In a study with 54 patients, those taking the probiotic Neobiotic Lactobalance® for 21 days saw significant reductions in diarrhea severity and abdominal pain, with scores dropping impressively on the Gastrointestinal Symptom Rating Scale.
Fecal analysis indicated improved intestinal health, highlighting Lactobacillus's potential benefits for those struggling with these conditions.
Read More
9.5
Probiotics improve H. pylori treatments
We analyzed various studies on incorporating probiotics into treatments for Helicobacter pylori (H. pylori) infection. Our findings revealed that adding probiotics like Bifidobacterium longum improved the eradication rate significantly.
Specifically, we noted that the probiotic group experienced fewer side effects, including diarrhea, nausea, and abdominal pain. This suggests that probiotics could not only enhance the effectiveness of H. pylori treatment but also make it more comfortable for patients. Overall, these results support the use of probiotics in gastric therapies.
Specifically, we noted that the probiotic group experienced fewer side effects, including diarrhea, nausea, and abdominal pain. This suggests that probiotics could not only enhance the effectiveness of H. pylori treatment but also make it more comfortable for patients. Overall, these results support the use of probiotics in gastric therapies.
Read More
9.5
We conducted a randomized double-blind, placebo-controlled trial with 200 participants to see how well the probiotic CECT 7347 (ES1) and its heat-treated version (HT-ES1) could help those suffering from diarrhea-predominant irritable bowel syndrome (IBS-D). After 12 weeks of treatment, both ES1 and HT-ES1 showed significant improvements in symptom severity, with marked reductions in IBS-SSS scores compared to the placebo.
Secondary benefits included better stool consistency and quality of life, making these treatments promising options for managing IBS-D symptoms. These findings reflect meaningful advancements in probiotic and postbiotic solutions.
Secondary benefits included better stool consistency and quality of life, making these treatments promising options for managing IBS-D symptoms. These findings reflect meaningful advancements in probiotic and postbiotic solutions.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
10
Life-changing product
This product has transformed my life. For a year, digestive issues plagued me, and my food intolerances kept escalating. I lost over 10 lbs and was apprehensive about eating anything. Previous probiotics exacerbated my issues. After starting Garden of Life Raw Probiotics, my stomach problems vanished in two days; I even managed to eat trigger foods without any issue. I now feel like a different person and never want to be without it.
Read More
10
Daily normalcy
Over the years, I've been plagued with persistent diarrhea, trying numerous diets and medications. At my wits' end, I started taking this product daily, and it has changed my life! Now, I only go to the toilet 1 to 2 times a day and, importantly, there's no diarrhoea. I can't believe the difference it has made; I’ll definitely buy it again and recommend it!
Read More
10
Normal bowel function
After being on IV antibiotics due to a dog bite, I continued experiencing terrible diarrhea despite taking multiple probiotics and kefir daily. My doctor suggested this brand. Within two days of switching, my situation normalised. My husband also suffered from severe diarrhea but after taking my probiotic, he has returned to normal as well. It's effective but quite expensive.
Read More
1
No relief experienced
Did not work. After a heavy course of antibiotics, I needed a good probiotic blend to repopulate my system. The antibiotics had triggered severe IBS. This product looked promising from its advertising but did absolutely nothing for me. After two weeks of taking them, I was still battling terrible diarrhea. I suspect that this product contained dead probiotics. I switched to a different brand and noticed results after just one day. Beware! You cannot know how these items are stored in the warehouse, and I believe they were kept at improper temperatures. A big waste of money. I will not purchase probiotics from Amazon again.
Read More
8.8
Minimised side effects
This product has been extremely effective in maintaining gut health. During a two-month antibiotic therapy, I faced none of the typical side effects like diarrhea or nausea, which I usually experience. I take these probiotics daily. They have no flavour and are easy to swallow. I recommend them to friends and family.
Read More
Frequently Asked Questions
Diarrhea is a condition characterized by the frequent passage of loose or watery stools, which can occur due to various factors, including infections, dietary choices, and underlying health conditions. It often results from the body's response to an irritation of the gastrointestinal tract, which can be caused by viruses, bacteria, parasites, or certain medications. While most cases tend to be short-lived and resolve on their own, diarrhea can lead to dehydration, especially in vulnerable populations such as young children and the elderly.
Managing diarrhea typically involves staying hydrated by drinking clear fluids and, when necessary, replenishing lost electrolytes. In some cases, over-the-counter medications may provide relief, although it’s essential to consult a healthcare professional for persistent or severe symptoms. A focus on bland, easy-to-digest foods can also help during recovery. Remember, if diarrhea persists for more than a couple of days or is accompanied by other concerning symptoms—like high fever, severe abdominal pain, or blood in stools—seeking medical attention is crucial.
Probiotics are live microorganisms, primarily bacteria, that are intended to provide health benefits when consumed in adequate amounts. These beneficial bacteria are often referred to as "good" or "friendly" bacteria because they help maintain a balanced gut microbiome, which plays a vital role in digestion, immune function, and overall health. Probiotics can be found in various foods such as yogurt, kefir, sauerkraut, and kombucha, as well as in dietary supplements. The most common strains include Lactobacillus and Bifidobacterium, which have been studied for their positive effects on gastrointestinal health, including the alleviation of symptoms related to irritable bowel syndrome (IBS) and diarrhea.
Incorporating probiotics into your diet may help support a healthy gut by competing with harmful bacteria and promoting a more diverse microbiome. However, it's important to note that the specific effects of probiotics can vary widely depending on the strain, dosage, and individual health conditions. While many people may benefit from including probiotics in their diet, it's advisable to consult a healthcare professional before starting any new supplement regimen, especially if you have underlying health issues or concerns. For those looking to explore the world of probiotics, it’s worth experimenting with various sources to find what works best for your body.
Probiotics have been shown to be effective in managing and reducing the duration of diarrhea, particularly in cases such as antibiotic-associated diarrhea and infectious diarrhea caused by viruses or bacteria. These beneficial bacteria help restore the natural balance of gut flora that can be disrupted due to illness or medication, thereby enhancing intestinal health. While not all strains of probiotics are equally effective, certain varieties, like Lactobacillus rhamnosus and Saccharomyces boulardii, have garnered support from clinical studies for their efficacy in alleviating diarrhea symptoms.
Incorporating probiotics into your diet can be as simple as consuming yogurt with live cultures, kefir, or specialized probiotic supplements. However, it’s essential to consult with a healthcare professional to determine the most appropriate strain and dosage for your specific situation. While probiotics may aid in recovery, they should not be seen as a sole treatment for serious diarrhea, and seeking medical advice is recommended if symptoms persist.
When taking probiotics for diarrhea, many users may start to notice improvements within 24 to 48 hours. However, the timeframe can vary significantly based on individual factors such as the specific probiotic strain used, the severity of the diarrhea, and the underlying cause of the issue. In some cases, it may take up to a week or more for people to experience the full benefits, especially for those dealing with chronic digestive issues.
It’s important to adhere to the recommended dosage and to give the probiotics time to work. For individuals dealing with acute diarrhea, such as that caused by antibiotic use or a mild gastrointestinal infection, you might find relief quicker. However, if symptoms persist beyond a few days or worsen, it’s advisable to consult a healthcare professional to ensure there are no underlying health concerns that need to be addressed.
Research supports that certain probiotics, particularly Lactobacillus acidophilus and Bifidobacterium lactis, have beneficial effects in reducing diarrhea symptoms in various populations. A study involving 94 children with rotavirus enteritis revealed that those receiving Lactobacillus acidophilus experienced quicker relief from diarrhea and associated symptoms compared to the control group (see research id='39586286'). Similarly, Bifidobacterium lactis has shown promise in treating acute diarrhea in children, leading to shorter durations and milder symptoms (see research id='37801459'). Multiple reviews indicate probiotics can effectively reduce the severity and duration of diarrhea, particularly in cases such as antibiotic-associated diarrhea (AAD) and gastrointestinal infections.
Moreover, additional research indicates that combinations of probiotics can enhance treatment efficacy. For instance, a probiotic blend demonstrated significant improvements in stool consistency and microbiota balance for infants suffering from gastrointestinal distress (see research id='36039996'). While not all studies uniformly show strong benefits, the cumulative data suggests that specific probiotics can be a valuable adjunct in managing diarrhea across different age groups and conditions.
The recommended dosage of probiotics for treating diarrhea can vary based on the specific strain of probiotics being used, as well as the age and health condition of the individual. Generally, studies suggest that doses ranging from 5 billion to 100 billion colony-forming units (CFUs) per day can be effective in managing diarrhea, including antibiotic-associated diarrhea and infectious diarrhea. It is important to choose a product that specifies the probiotic strains known to be beneficial, such as Lactobacillus rhamnosus GG or Saccharomyces boulardii, which have shown efficacy in clinical trials.
When considering probiotics for diarrhea treatment, it’s also wise to consult with a healthcare professional to determine the appropriate type and dosage based on individual health needs. Some formulations may be more effective for specific types of diarrhea, and personalized recommendations can help ensure optimal results. Remember to pay attention to product labeling for CFU counts and strain specifications to ensure you’re getting a high-quality product that can support gut health effectively.
References
- Li S, Lu T, Lin Z, Zhang Y, Zhou X, et al. Supplementation with probiotics co-cultivation improves the reproductive performance in a sow-piglet model by mother-infant microbiota transmission and placental mTOR signaling. World J Microbiol Biotechnol. 2024;41:13. doi:10.1007/s11274-024-04222-5
- Hashem B, Gaston M, Carlisle JD, Van Wick P. COMPARISON OF HAND-REARED PRONGHORN () MILK REPLACER COMPOSITIONS AND GROWTH RATES. J Zoo Wildl Med. 2024;55:1056. doi:10.1638/2023-0112
- Wei Q, Song LY, Rao R, Yang HW, Wen YP, et al. The Impact of Combined Therapy with Lactobacillus acidophilus and Montmorillonite Powder on the Inflammatory Response in Pediatric Rotavirus Enteritis. Int Arch Allergy Immunol. 2024. doi:10.1159/000542593
- Jeong JJ, Jin YJ, Ganesan R, Park HJ, Min BH, et al. Multistrain Probiotics Alleviate Diarrhea by Modulating Microbiome-Derived Metabolites and Serotonin Pathway. Probiotics Antimicrob Proteins. 2024. doi:10.1007/s12602-024-10232-4
- Alharbi BF, Alateek AA. Investigating the influence of probiotics in preventing Traveler's diarrhea: Meta-analysis based systematic review. Travel Med Infect Dis. 2024;59:102703. doi:10.1016/j.tmaid.2024.102703
- Miranda-Yuquilema J, Taboada J, Once V, Coyago M, Briñez W. Effect of Agroindustrial Waste Substrate Fermented with Lactic Acid Bacteria and Yeast on Changes in the Gut Microbiota of Guinea Pigs. Microorganisms. 2024;12. doi:10.3390/microorganisms12010133
- Shanshal SA, Alsaaty MH, Al-Qazaz H, Al-Zidan RN. Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial. Ceska Slov Farm. 2024;72:233.
- Shanshal SA, Alsaaty MH, Al-Qazaz H, Al-Zidan RN. Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial. Ceska Slov Farm. 2024;73:233.
- Higuchi T, Furuichi M, Maeda N, Tsugawa T, Ito K. Effects of probiotics in children with acute gastroenteritis: A systematic review and meta-analysis focusing on probiotics utilized in Japan. J Infect Chemother. 2024;30:337. doi:10.1016/j.jiac.2023.11.005
- Drozdov VN, Shikh EV, Astapovskii AA, Khalaidzheva KN, Solovieva SA, et al. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea and antibiotic-associated diarrhea]. Vopr Pitan. 2023;92:92. doi:10.33029/0042-8833-2023-92-4-92-103
- Lukasik J, Dierikx T, Besseling-van der Vaart I, de Meij T, Szajewska H. Multispecies Probiotic for the Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Clinical Trial. JAMA Pediatr. 2022;176:860. doi:10.1001/jamapediatrics.2022.1973
- Huang R, Xing HY, Liu HJ, Chen ZF, Tang BB. Efficacy of probiotics in the treatment of acute diarrhea in children: a systematic review and meta-analysis of clinical trials. Transl Pediatr. 2021;10:3248. doi:10.21037/tp-21-511
- Gandhar JS, De UK, Kala A, Malik YS, Yadav S, et al. Efficacy of Microencapsulated Probiotic as Adjunct Therapy on Resolution of Diarrhea, Copper-Zinc Homeostasis, Immunoglobulins, and Inflammatory Markers in Serum of Spontaneous Rotavirus-Infected Diarrhoetic Calves. Probiotics Antimicrob Proteins. 2022;14:1054. doi:10.1007/s12602-021-09862-9
- Kumar M, Kala A, Chaudhary LC, Agarwal N, Kochewad SA. Microencapsulated and Lyophilized Lactobacillus acidophilus Improved Gut Health and Immune Status of Preruminant Calves. Probiotics Antimicrob Proteins. 2022;14:523. doi:10.1007/s12602-021-09821-4
- Chorawala MR, Chauhan S, Patel R, Shah G. Cell Wall Contents of Probiotics (Lactobacillus species) Protect Against Lipopolysaccharide (LPS)-Induced Murine Colitis by Limiting Immuno-inflammation and Oxidative Stress. Probiotics Antimicrob Proteins. 2021;13:1005. doi:10.1007/s12602-020-09738-4
- Gunaratnam S, Diarra C, Paquette PD, Ship N, Millette M, et al. The Acid-Dependent and Independent Effects of Lactobacillus acidophilus CL1285, Lacticaseibacillus casei LBC80R, and Lacticaseibacillus rhamnosus CLR2 on Clostridioides difficile R20291. Probiotics Antimicrob Proteins. 2021;13:949. doi:10.1007/s12602-020-09729-5
- Shin I, Kang Y, Ahn J, Kim Y, Nam J, et al. The potential probiotic role of Lacticaseibacillus rhamnosus on growth performance, gut health, and immune responses of weaned pigs. J Anim Sci. 2025. doi:10.1093/jas/skaf089
- Chen K, Zeng K, Jin S, Ma Y, Cai L, et al. LRa05 in the treatment of acute diarrhea in children: a randomized controlled trial. Front Nutr. 2024;11:1479186. doi:10.3389/fnut.2024.1479186
- Gwee KA, Lee WRW, Chua Q, Chiou FK, Aw MM, et al. The evidence for probiotics in the treatment of digestive disorders in the pediatric population. J Gastroenterol Hepatol. 2025;40:41. doi:10.1111/jgh.16809
- Shah J, Adnan SH, Yousaf MS, Din SJU, Haq MU, et al. A Multi-Hospital Comparative Study on the Efficacy of Probiotics Versus Placebo in Preventing Antibiotic-Associated Diarrhea in Adult Patients. Cureus. 2024;16:e70881. doi:10.7759/cureus.70881
- Shawky LM, Abo El Wafa SM, Behery M, Bahr MH, Abu Alnasr MT, et al. Lactobacillus rhamnosus GG and Tannic Acid Synergistically Promote the Gut Barrier Integrity in a Rat Model of Experimental Diarrhea via Selective Immunomodulatory Cytokine Targeting. Mol Nutr Food Res. 2024;68:e2400295. doi:10.1002/mnfr.202400295
- Anvarifard P, Anbari M, Ghalichi F, Ghoreishi Z, Zarezadeh M. The effectiveness of probiotics as an adjunct therapy in patients under mechanical ventilation: an umbrella systematic review and meta-analysis. Food Funct. 2024;15:5737. doi:10.1039/d3fo04653b
- Alharbi BF, Alateek AA. Investigating the influence of probiotics in preventing Traveler's diarrhea: Meta-analysis based systematic review. Travel Med Infect Dis. 2024;59:102703. doi:10.1016/j.tmaid.2024.102703
- Abdulah DM, Sulaiman SJ, Ahmed ZW. Effect of probiotics plus zinc supplementation on clinical outcomes of infants and children with acute infectious diarrhea: a randomized controlled trial. Clin Exp Pediatr. 2024;67:203. doi:10.3345/cep.2023.01340
- Waitzberg D, Guarner F, Hojsak I, Ianiro G, Polk DB, et al. Can the Evidence-Based Use of Probiotics (Notably Saccharomyces boulardii CNCM I-745 and Lactobacillus rhamnosus GG) Mitigate the Clinical Effects of Antibiotic-Associated Dysbiosis?. Adv Ther. 2024;41:901. doi:10.1007/s12325-024-02783-3
- Saviano A, Petruzziello C, Cancro C, Macerola N, Petti A, et al. The Efficacy of a Mix of Probiotics ( LMG P-27481 and GG ATCC 53103) in Preventing Antibiotic-Associated Diarrhea and Infection in Hospitalized Patients: Single-Center, Open-Label, Randomized Trial. Microorganisms. 2024;12. doi:10.3390/microorganisms12010198
- Poeta M, Cioffi V, Tarallo A, Damiano C, Lo Vecchio A, et al. Postbiotic Preparation of against Diarrhea and Oxidative Stress Induced by Spike Protein of SARS-CoV-2 in Human Enterocytes. Antioxidants (Basel). 2023;12. doi:10.3390/antiox12101878
- Drozdov VN, Shikh EV, Astapovskii AA, Khalaidzheva KN, Solovieva SA, et al. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea and antibiotic-associated diarrhea]. Vopr Pitan. 2023;92:92. doi:10.33029/0042-8833-2023-92-4-92-103
- Mego M, Danis R, Chovanec J, Jurisova S, Bystricky B, et al. Randomized double-blind, placebo-controlled multicenter phase III study of prevention of irinotecan-induced diarrhea by a probiotic mixture containing Bifidobacterium BB-12 LGG in colorectal cancer patients. Front Oncol. 2023;13:1168654. doi:10.3389/fonc.2023.1168654
- Yang Q, Hu Z, Lei Y, Li X, Xu C, et al. Overview of systematic reviews of probiotics in the prevention and treatment of antibiotic-associated diarrhea in children. Front Pharmacol. 2023;14:1153070. doi:10.3389/fphar.2023.1153070
- Niu H, Zhou X, Liu P, Wu Y, Lyu L, et al. Lactobacillus rhamnosus MN-431 Metabolic Tryptophan Alleviates Complementary Food-Induced Diarrhea through PXR-NF-κB Pathway and AHR-Th17 Cell Response Pathways. Mol Nutr Food Res. 2023;67:e2200530. doi:10.1002/mnfr.202200530
- Li J, Li Q, Wu Q, Gao N, Wang Z, et al. Exopolysaccharides of Lactobacillus rhamnosus GG ameliorate Salmonella typhimurium-induced intestinal inflammation via the TLR4/NF-κB/MAPK pathway. J Anim Sci Biotechnol. 2023;14:23. doi:10.1186/s40104-023-00830-7
- Tanashat M, Abuelazm M, Abouzid M, Al-Ajlouni YA, Ramadan A, et al. Efficacy of probiotics regimens for Helicobacter pylori eradication: A systematic review, pairwise, and network meta-analysis of randomized controlled trials. Clin Nutr ESPEN. 2025;65:424. doi:10.1016/j.clnesp.2024.11.016
- Chen K, Zeng K, Jin S, Ma Y, Cai L, et al. LRa05 in the treatment of acute diarrhea in children: a randomized controlled trial. Front Nutr. 2024;11:1479186. doi:10.3389/fnut.2024.1479186
- Shah J, Adnan SH, Yousaf MS, Din SJU, Haq MU, et al. A Multi-Hospital Comparative Study on the Efficacy of Probiotics Versus Placebo in Preventing Antibiotic-Associated Diarrhea in Adult Patients. Cureus. 2024;16:e70881. doi:10.7759/cureus.70881
- Moreno-Muñoz JA, Ojeda JD, López JJ. A Probiotic Bacterium with Activity against the Most Frequent Bacteria and Viruses Causing Pediatric Diarrhea: subsp. CECT 7210 ( IM1). Microorganisms. 2024;12. doi:10.3390/microorganisms12061183
- Srivastava S, Basak U, Naghibi M, Vijayakumar V, Parihar R, et al. A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live CECT 7347 (ES1) and heat-treated CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome. Gut Microbes. 2024;16:2338322. doi:10.1080/19490976.2024.2338322
- Drozdov VN, Shikh EV, Astapovskii AA, Khalaidzheva KN, Solovieva SA, et al. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea and antibiotic-associated diarrhea]. Vopr Pitan. 2023;92:92. doi:10.33029/0042-8833-2023-92-4-92-103
- Lenoir M, Wienke J, Fardao-Beyler F, Roese N. An 8-Week Course of Bifidobacterium longum 35624 Is Associated with a Reduction in the Symptoms of Irritable Bowel Syndrome. Probiotics Antimicrob Proteins. 2025;17:315. doi:10.1007/s12602-023-10151-w
- Chen K, Jin S, Ma Y, Cai L, Xu P, et al. Adjunctive efficacy of Lactis XLTG11 for Acute diarrhea in children: A randomized, blinded, placebo-controlled study. Nutrition. 2023;111:112052. doi:10.1016/j.nut.2023.112052
- Li W, Zhang S, Wang Y, Bian H, Yu S, et al. Complex probiotics alleviate ampicillin-induced antibiotic-associated diarrhea in mice. Front Microbiol. 2023;14:1156058. doi:10.3389/fmicb.2023.1156058
- Mizutani Y, Kawamoto S, Takahashi M, Doi H, Wakida K, et al. Efficacy and Safety of Synbiotics in Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation: A Randomized, Double-blinded, Placebo-controlled Pilot Study. Intern Med. 2023;62:2949. doi:10.2169/internalmedicine.1314-22
- Yalcin G, Demirbas F, Bacalan F, Toy EB. Evaluation of treatment in acute gastroenteritis: A comparative study. J Pak Med Assoc. 2022;72:2019. doi:10.47391/JPMA.4438
- Li W, Kai L, Jiang Z, He H, Yang M, et al. , and Reversed ETEC-Inducing Intestinal Inflammation in Mice. Microorganisms. 2022;10. doi:10.3390/microorganisms10122350
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