' 
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.6
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 4 Capsules
Serving Per Container: 30
Amount Per Serving
%DV
Vitamin C (from culture of S. cerevisiae)
50 mg
56%
Vitamin D (as D3 from culture of S. cerevisiae)
40 mcg (1,600 IU)
200%
Vitamin K (from culture of S. cerevisiae)
120 mcg
100%
Calcium (naturally occurring from Algae)
1,100 mg
85%
Magnesium (from Algae and Dead Sea minerals)
357 mg
85%
Vitamin K (as K2 MK-7)
50 mcg
+
Strontium (naturally occurring from Algae)
3.8 mg
+
Boron (from Brown Rice Chelate)
3 mg
+
Silica (naturally occurring from Algae)
2.2 mg
+
Vanadium (naturally occurring from Algae)
25 mcg
+
Raw Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, [Lactobacillus bulgaricus, Lactobacillus plantarum] (500 Million CFU).
64 mg
+
Top Medical Research Studies
8
Magnesium alloy inhibits cancer growth
Biodegradable Mg-1%Ca alloy inhibits the growth of cervical cancer.
Significant effects on cervical cancer
We explored how magnesium alloy, particularly a variant containing 1% calcium, impacts cervical cancer cells. Our investigation revealed that this alloy has promising antitumor properties which could pave the way for new treatments.
In our experiments, we tested the effects of the Mg-1%Ca alloy both in laboratory settings and in living organisms. This alloy was found to release magnesium ions and hydroxide ions more slowly than expected. We observed that it effectively inhibited the growth of cervical cancer cells, specifically SiHa and HeLa cell lines.
Additionally, the presence of the alloy induced apoptosis, or programmed cell death, in the cancer cells, disrupted their structural integrity, and hindered their ability to migrate and invade other tissues. Importantly, the Mg-1%Ca alloy was seen to influence key molecular pathways, specifically the MAPK/ERK signaling pathway, which plays a role in cancer cell proliferation.
With these results, it's evident that magnesium alloy could serve as a useful adjunct to current cervical cancer therapies, potentially helping to prevent both cancer growth and metastasis.
In our experiments, we tested the effects of the Mg-1%Ca alloy both in laboratory settings and in living organisms. This alloy was found to release magnesium ions and hydroxide ions more slowly than expected. We observed that it effectively inhibited the growth of cervical cancer cells, specifically SiHa and HeLa cell lines.
Additionally, the presence of the alloy induced apoptosis, or programmed cell death, in the cancer cells, disrupted their structural integrity, and hindered their ability to migrate and invade other tissues. Importantly, the Mg-1%Ca alloy was seen to influence key molecular pathways, specifically the MAPK/ERK signaling pathway, which plays a role in cancer cell proliferation.
With these results, it's evident that magnesium alloy could serve as a useful adjunct to current cervical cancer therapies, potentially helping to prevent both cancer growth and metastasis.
Read More
8
Magnesium's potential in cancer therapy
Elevated serum magnesium levels prompt favourable outcomes in cancer patients treated with immune checkpoint blockers.
Moderate relevance to cancer research
We observed intriguing connections between magnesium levels and cancer treatment outcomes. Our focus was on how elevated serum magnesium might influence the effectiveness of immune checkpoint blockers, a promising class of cancer therapy.
While our findings suggest a potential benefit of higher magnesium levels in conjunction with these treatments, it’s important to note that isolating the effects of magnesium alone was challenging. We found that patients who had elevated magnesium levels experienced more favorable outcomes, yet we must remain cautious in interpreting these results as definitive proof of magnesium's standalone effectiveness.
Overall, the investigation into magnesium's impact on cancer treatment highlights an interesting avenue for future research. Understanding how our bodies' minerals interact with innovative therapies like immune checkpoint blockers could open new doors in the fight against cancer.
While our findings suggest a potential benefit of higher magnesium levels in conjunction with these treatments, it’s important to note that isolating the effects of magnesium alone was challenging. We found that patients who had elevated magnesium levels experienced more favorable outcomes, yet we must remain cautious in interpreting these results as definitive proof of magnesium's standalone effectiveness.
Overall, the investigation into magnesium's impact on cancer treatment highlights an interesting avenue for future research. Understanding how our bodies' minerals interact with innovative therapies like immune checkpoint blockers could open new doors in the fight against cancer.
Read More
5
Vitamin D's role in breast disease
Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study.
Study shows potential vitamin D impact
We conducted an observational study to examine the levels of vitamin D in female patients with benign and malignant breast diseases. The research aimed to determine if there is a significant difference in vitamin D levels between those with non-cancerous conditions and those diagnosed with breast cancer.
During the study, we analyzed adult female patients admitted to a surgical department. Importantly, we excluded those who had taken vitamin D supplements recently or who had prior vitamin D deficiencies. By measuring serum vitamin D levels through a specific testing method, we were able to gather meaningful data about their relationship to breast health.
Our findings indicated a notable difference in average vitamin D levels when comparing the two groups. This suggests that inadequate vitamin D could be linked to an increased risk of developing breast cancer. Therefore, we explored the potential benefits of vitamin D supplementation as a preventive measure against breast cancer—though we acknowledge that larger and more controlled studies are essential to draw firm conclusions.
At the same time, we recognize that vitamin D has effects beyond bone health, and it is crucial to consider these broader impacts when discussing its role in cancer risk.
During the study, we analyzed adult female patients admitted to a surgical department. Importantly, we excluded those who had taken vitamin D supplements recently or who had prior vitamin D deficiencies. By measuring serum vitamin D levels through a specific testing method, we were able to gather meaningful data about their relationship to breast health.
Our findings indicated a notable difference in average vitamin D levels when comparing the two groups. This suggests that inadequate vitamin D could be linked to an increased risk of developing breast cancer. Therefore, we explored the potential benefits of vitamin D supplementation as a preventive measure against breast cancer—though we acknowledge that larger and more controlled studies are essential to draw firm conclusions.
At the same time, we recognize that vitamin D has effects beyond bone health, and it is crucial to consider these broader impacts when discussing its role in cancer risk.
Read More
Most Useful Reviews
9.5
Enhanced anti-cancer immunity
I have been taking this for five years to enhance my anti-cancer immunity, and it exhibits the highest efficacy among calcium products.
Read More
8.8
Improved calcium levels
As a cancer patient, this product significantly boosted my calcium levels. The packaging was neatly done, and I noticed considerable improvement in my bones. God bless. 🙌🏽
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.6
- All Researches
9
Vitamin D enhances chemotherapy delivery
Enzyme-responsive vitamin D-based micelles for paclitaxel-controlled delivery and synergistic pancreatic cancer therapy.
Vitamin D's role in synergy
We explored the potential of vitamin D-based micelles designed to deliver paclitaxel, a key chemotherapy drug, specifically for pancreatic cancer treatment. This study focuses on developing enzyme-responsive micelles that not only carry paclitaxel but also utilize vitamin D as an integral part of the delivery system.
The micelles are made by combining vitamin D with polyethylene glycol, resulting in tiny structures that can release their drug load when interacting with enzymes typically found in pancreatic cancer cells. We observed that these micelles showed promising results in laboratory settings, enhancing the effectiveness of paclitaxel against aggressive pancreatic cancer cells compared to using paclitaxel alone.
Moreover, we noted that the vitamin D in the micelles may play a dual role: serving as both a hydrophobic core for drug delivery and a contributor to synergetic therapeutic effects. Our findings suggest that leveraging vitamin D in this way could increase the efficacy of existing treatment options for pancreatic cancer patients, which is particularly significant given the challenges currently faced in treating this disease.
The micelles are made by combining vitamin D with polyethylene glycol, resulting in tiny structures that can release their drug load when interacting with enzymes typically found in pancreatic cancer cells. We observed that these micelles showed promising results in laboratory settings, enhancing the effectiveness of paclitaxel against aggressive pancreatic cancer cells compared to using paclitaxel alone.
Moreover, we noted that the vitamin D in the micelles may play a dual role: serving as both a hydrophobic core for drug delivery and a contributor to synergetic therapeutic effects. Our findings suggest that leveraging vitamin D in this way could increase the efficacy of existing treatment options for pancreatic cancer patients, which is particularly significant given the challenges currently faced in treating this disease.
Read More
9
Magnesium and Cancer Treatment Outcomes
Letter Re: Elevated serum magnesium levels prompt favourable outcomes in cancer patients treated with immune checkpoint blockers.
Magnesium correlation, not causation
We looked into the question of how magnesium levels might affect cancer treatment outcomes, especially for patients receiving immune checkpoint blockers. The study pointed out that elevated serum magnesium levels corresponded with more favorable results in these patients, suggesting that magnesium could play a positive role in their treatment journey.
However, the findings did not specifically isolate the effects of magnesium from those of other treatments. This means that while we observed a correlation between high magnesium levels and improved outcomes, we can't definitively say that magnesium alone caused these results. It’s important to note that further research is needed to clarify this relationship and understand how magnesium interacts with cancer therapies.
Overall, while the presence of sufficient magnesium appears to be beneficial, the intricate connection between magnesium levels and cancer treatment success is still not fully understood.
However, the findings did not specifically isolate the effects of magnesium from those of other treatments. This means that while we observed a correlation between high magnesium levels and improved outcomes, we can't definitively say that magnesium alone caused these results. It’s important to note that further research is needed to clarify this relationship and understand how magnesium interacts with cancer therapies.
Overall, while the presence of sufficient magnesium appears to be beneficial, the intricate connection between magnesium levels and cancer treatment success is still not fully understood.
Read More
9
Magnesium enhances cancer immunotherapy
Magnesium peroxide-based biomimetic nanoigniter degrades extracellular matrix to awake T cell-mediated cancer immunotherapy.
Magnesium's effect not fully isolated
We examined how magnesium plays a role in enhancing T cell-mediated cancer immunotherapy. The study focused on a unique magnesium peroxide-based nanoigniter designed to disrupt the tumors' defenses. By combating the challenging immunosuppressive environment surrounding tumors, this innovative treatment aims to allow T cells to attack more effectively.
The nanoigniter is loaded with doxorubicin and metformin, and it works doubly by breaking down the tough extracellular matrix (ECM) that makes it difficult for T cells to infiltrate tumors. We observed that this approach not only promotes stronger responses from CD8 T cells — a critical type of immune cell in our bodies — but also boosts their effectiveness and prevents their fatigue under harsh conditions.
While the study highlights magnesium's supportive role in improving immunotherapy outcomes, it does not isolate the mineral's direct impact on cancer. Therefore, while we see promising interactions, determining magnesium's specific effects remains complex and linked to the overall treatment plan.
The nanoigniter is loaded with doxorubicin and metformin, and it works doubly by breaking down the tough extracellular matrix (ECM) that makes it difficult for T cells to infiltrate tumors. We observed that this approach not only promotes stronger responses from CD8 T cells — a critical type of immune cell in our bodies — but also boosts their effectiveness and prevents their fatigue under harsh conditions.
While the study highlights magnesium's supportive role in improving immunotherapy outcomes, it does not isolate the mineral's direct impact on cancer. Therefore, while we see promising interactions, determining magnesium's specific effects remains complex and linked to the overall treatment plan.
Read More
9
Magnesium enhances glioblastoma treatment
Magnesium-Phenolic Nanoeditor Refining Gliomatous T Cells for Metalloimmunotherapy.
Moderate relevance due to combination
We investigated how magnesium might enhance the effectiveness of cytotoxic T lymphocytes (CTLs) in fighting glioblastoma, a particularly aggressive form of brain cancer. CTLs, although present in glioblastoma, often struggle to infiltrate tumors effectively and are hampered by various inhibitory markers, notably NK1.1.
This study introduced a novel method using a specially designed nanoeditor, named Mg@MK-8931@MPP. This editor combines magnesium with a specific drug that helps empower CTLs and encourages their infiltration into the tumor while addressing the challenges of delivering treatment safely in the brain.
We observed that once the magnesium-based nanoeditor localized within glioblastoma, it enabled the effective release of MK-8931. This release repolarized M2-like macrophages, promoting a more significant CTL presence within the tumor site. Furthermore, magnesium worked to amplify the immune response, boosting the production of crucial antitumor cytokines and proteins.
Additionally, we found that blocking the NK1.1 receptor on CTLs extended their cytotoxic activity, enhancing treatment outcomes. Research on both T-cell-deficient and standard mouse models validated the potential of this magnesium-driven metalloimmunotherapy approach in treating glioblastoma effectively.
Overall, this strategy not only broadens the application of metalloimmunotherapy to glioblastoma but also emphasizes the importance of ensuring the functionality of CTLs in the fight against cancer.
This study introduced a novel method using a specially designed nanoeditor, named Mg@MK-8931@MPP. This editor combines magnesium with a specific drug that helps empower CTLs and encourages their infiltration into the tumor while addressing the challenges of delivering treatment safely in the brain.
We observed that once the magnesium-based nanoeditor localized within glioblastoma, it enabled the effective release of MK-8931. This release repolarized M2-like macrophages, promoting a more significant CTL presence within the tumor site. Furthermore, magnesium worked to amplify the immune response, boosting the production of crucial antitumor cytokines and proteins.
Additionally, we found that blocking the NK1.1 receptor on CTLs extended their cytotoxic activity, enhancing treatment outcomes. Research on both T-cell-deficient and standard mouse models validated the potential of this magnesium-driven metalloimmunotherapy approach in treating glioblastoma effectively.
Overall, this strategy not only broadens the application of metalloimmunotherapy to glioblastoma but also emphasizes the importance of ensuring the functionality of CTLs in the fight against cancer.
Read More
8
Vitamin D analogs in prostate cancer
[New insights of vitamin D-based therapy for prostate cancer].
Examines vitamin D's cancer effects
We explored the potential benefits of a vitamin D analog in treating prostate cancer, which is a major cause of cancer-related deaths among men. Our work focused on understanding how this vitamin D form impacts cancer resistance and the tumor microenvironment. We used the Pten mouse model to observe the therapeutic effects of the vitamin D analog.
One significant finding was that combining this vitamin D analog with the chemotherapy drug docetaxel could overcome resistance seen in some prostate cancer cases. This combination showed promising results in primary cancer spheroids and xenografts from a patient whose cancer had resisted both docetaxel and androgen deprivation therapy.
These insights suggest that vitamin D analogs might offer new and effective strategies for managing advanced prostate cancer, particularly for those patients who have not responded well to standard treatments.
One significant finding was that combining this vitamin D analog with the chemotherapy drug docetaxel could overcome resistance seen in some prostate cancer cases. This combination showed promising results in primary cancer spheroids and xenografts from a patient whose cancer had resisted both docetaxel and androgen deprivation therapy.
These insights suggest that vitamin D analogs might offer new and effective strategies for managing advanced prostate cancer, particularly for those patients who have not responded well to standard treatments.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Enhanced anti-cancer immunity
I have been taking this for five years to enhance my anti-cancer immunity, and it exhibits the highest efficacy among calcium products.
8.8
Improved calcium levels
As a cancer patient, this product significantly boosted my calcium levels. The packaging was neatly done, and I noticed considerable improvement in my bones. God bless. 🙌🏽
