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SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.5
USERS' SCORE
Good
Based on 3 Reviews
8.6
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Vitamin D (as D3 from culture of Saccharomyces cerevisiae)
125 mcg (5,000 IU)
625%
High Omega-9 Cracked-Wall Chlorella
250 mg
+
RAW Organic Fruit & Vegetable BlendOrganic Apple (fruit), Organic Beet (root), Organic Broccoli (stalk & flower), Organic Carrot (root), Organic Spinach (leaf), Organic Tomato (fruit), Organic Strawberry (fruit), Organic Tart Cherry (fruit), Organic Green Bell Pepper (fruit), Organic Blackberry (fruit), Organic Brussels Sprout (leaf), Organic Ginger (root), Organic Garlic (bulb), Organic Green Onion (bulb), Organic Blueberry (fruit), Organic Parsley (leaf), Organic Cauliflower (flower & stem), Organic Raspberry (fruit), Organic Red Cabbage (leaf), Organic Kale (leaf), Organic Cucumber (gourd), Organic Celery (stalk), Organic Asparagus (flower & stem)
150 mg
+
RAW Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, [Lactobacillus bulgaricus, Lactobacillus plantarum] (500 Million CFU)
60 mg
+
Top Medical Research Studies
8
High-dose vitamin D reduces anxiety
Effects of an 8-week high-dose vitamin D supplementation on fatigue and neuropsychiatric manifestations in post-COVID syndrome: A randomized controlled trial.
Directly assesses vitamin D's impact
We conducted a study to understand how high-dose vitamin D supplementation might impact anxiety levels, particularly in patients experiencing post-COVID symptoms. In our double-blind, randomized controlled trial, we enrolled 80 individuals dealing with fatigue or neuropsychiatric issues after COVID-19.
Participants were split into two groups: one received a weekly dose of 60,000 IU of vitamin D, while the other group received a placebo. Over eight weeks, we evaluated various outcomes, including anxiety levels using the Depression, Anxiety, and Stress Scale (DASS-21).
The results were encouraging for the vitamin D group. We observed significant improvements in anxiety levels, with a notable reduction reported by participants. However, other measures related to sleep quality, depression, cognitive function, and inflammatory markers did not show similar significant changes.
Importantly, we found that the vitamin D group reported no serious adverse effects, indicating that this supplementation is generally safe. These findings suggest that high-dose vitamin D may offer substantial benefits for anxiety relief in patients recovering from COVID-19, albeit with limited effects on other symptoms.
Participants were split into two groups: one received a weekly dose of 60,000 IU of vitamin D, while the other group received a placebo. Over eight weeks, we evaluated various outcomes, including anxiety levels using the Depression, Anxiety, and Stress Scale (DASS-21).
The results were encouraging for the vitamin D group. We observed significant improvements in anxiety levels, with a notable reduction reported by participants. However, other measures related to sleep quality, depression, cognitive function, and inflammatory markers did not show similar significant changes.
Importantly, we found that the vitamin D group reported no serious adverse effects, indicating that this supplementation is generally safe. These findings suggest that high-dose vitamin D may offer substantial benefits for anxiety relief in patients recovering from COVID-19, albeit with limited effects on other symptoms.
Read More
8
Link between Vitamin D and anxiety
Association of serum vitamin D with anxiety in US adults: a cross-sectional study.
High relevance for vitamin D research
We examined if there is a connection between vitamin D levels and anxiety among US adults, utilizing data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2007 and 2012. The study included over 12,000 participants and employed sophisticated statistical methods to determine the relationship between serum vitamin D and anxiety.
Our analyses revealed that higher levels of serum vitamin D were associated with a lower risk of experiencing anxiety. Specifically, we found a significant inverse relationship; as vitamin D levels increased, the likelihood of anxiety decreased. This connection remained strong even after adjusting for various factors that could influence the results.
Furthermore, smooth curve fitting techniques confirmed a negative association between vitamin D and anxiety risk. Nonetheless, while these findings are promising, we emphasize the need for further prospective studies to validate these results and fully understand the implications of vitamin D on mental health.
Our analyses revealed that higher levels of serum vitamin D were associated with a lower risk of experiencing anxiety. Specifically, we found a significant inverse relationship; as vitamin D levels increased, the likelihood of anxiety decreased. This connection remained strong even after adjusting for various factors that could influence the results.
Furthermore, smooth curve fitting techniques confirmed a negative association between vitamin D and anxiety risk. Nonetheless, while these findings are promising, we emphasize the need for further prospective studies to validate these results and fully understand the implications of vitamin D on mental health.
Read More
8
Vitamin D mitigates anxiety symptoms
Placenta-specific CYP11A1 overexpression lead to autism-like symptom in offspring with altered steroid hormone biosynthesis in the placenta-brain axis and rescued by vitamin D intervention.
Strong relevance to vitamin D effects
We explored the impact of changing levels of a specific enzyme, CYP11A1, in the placenta and how it might influence anxiety and social behavior in offspring. Using a unique mouse model, we found that higher levels of this enzyme are associated with behaviors similar to those seen in autism spectrum disorders (ASD), such as reduced social interaction and increased anxiety.
Interestingly, we observed that these anxiety-related behaviors improved significantly after administering vitamin D3. Behavioral tests, including open field and elevated plus maze assessments, showed that the mice exhibited less anxiety when given this supplement.
Additionally, our study highlighted that vitamin D3 could help correct some of the hormonal imbalances linked to CYP11A1 overexpression. Higher progesterone levels and increased inflammation were noted in the affected mice, and these issues seemed to reverse with vitamin D3 treatment.
This research underscores not only the potential role of vitamin D in managing anxiety but also suggests that examining CYP11A1 levels could be important for understanding and perhaps preventing some neurodevelopmental disorders. Overall, it appears vitamin D3 may serve as a useful tool in mitigating anxiety linked to hormonal changes during development.
Interestingly, we observed that these anxiety-related behaviors improved significantly after administering vitamin D3. Behavioral tests, including open field and elevated plus maze assessments, showed that the mice exhibited less anxiety when given this supplement.
Additionally, our study highlighted that vitamin D3 could help correct some of the hormonal imbalances linked to CYP11A1 overexpression. Higher progesterone levels and increased inflammation were noted in the affected mice, and these issues seemed to reverse with vitamin D3 treatment.
This research underscores not only the potential role of vitamin D in managing anxiety but also suggests that examining CYP11A1 levels could be important for understanding and perhaps preventing some neurodevelopmental disorders. Overall, it appears vitamin D3 may serve as a useful tool in mitigating anxiety linked to hormonal changes during development.
Read More
Most Useful Reviews
9.5
Remarkable anxiety relief
A True Game-Changer. These vitamins have drastically improved my life! I suffered from severe anxiety, among other symptoms, but noticed a remarkable difference within 1-1.5 weeks of taking them. My energy level increased and all unpleasant symptoms seemed to fade, including my anxiety surrounding driving. I continue to take a higher dosage because I noticed a negative difference with lesser brands. I am so grateful to have discovered these vitamins and will ensure I never run out!
Read More
8.8
Improved sleep quality
Excellent, particularly for black men! I purchase these for my family along with Adam Now multis and Omegavia fish oil pills. Black men often have low Vitamin D levels unless they work in the sun. My brother struggled with insomnia and anxiety, but this, along with Calm Magnesium, significantly improved his sleep and daytime energy. He stopped once his D levels normalised and fell back into the same issues. A cheaper brand didn't help, making this a staple in our household. Most people are deficient, particularly the elderly and those with specific health issues, so I see no reason to stop using it. My ex, fit and healthy, was often tired and irritable with low testosterone but found these beneficial alongside his prescription.
Read More
9.5
Anxiety relief observed
Noticeable difference! I purchased this for my teenage daughter, who began experiencing panic and anxiety. After 30 days of use, there was a significant improvement. She expressed her gratitude, and we now have them on subscribe and save.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.5
8
High-dose vitamin D reduces anxiety
Effects of an 8-week high-dose vitamin D supplementation on fatigue and neuropsychiatric manifestations in post-COVID syndrome: A randomized controlled trial.
Directly assesses vitamin D's impact
We conducted a study to understand how high-dose vitamin D supplementation might impact anxiety levels, particularly in patients experiencing post-COVID symptoms. In our double-blind, randomized controlled trial, we enrolled 80 individuals dealing with fatigue or neuropsychiatric issues after COVID-19.
Participants were split into two groups: one received a weekly dose of 60,000 IU of vitamin D, while the other group received a placebo. Over eight weeks, we evaluated various outcomes, including anxiety levels using the Depression, Anxiety, and Stress Scale (DASS-21).
The results were encouraging for the vitamin D group. We observed significant improvements in anxiety levels, with a notable reduction reported by participants. However, other measures related to sleep quality, depression, cognitive function, and inflammatory markers did not show similar significant changes.
Importantly, we found that the vitamin D group reported no serious adverse effects, indicating that this supplementation is generally safe. These findings suggest that high-dose vitamin D may offer substantial benefits for anxiety relief in patients recovering from COVID-19, albeit with limited effects on other symptoms.
Participants were split into two groups: one received a weekly dose of 60,000 IU of vitamin D, while the other group received a placebo. Over eight weeks, we evaluated various outcomes, including anxiety levels using the Depression, Anxiety, and Stress Scale (DASS-21).
The results were encouraging for the vitamin D group. We observed significant improvements in anxiety levels, with a notable reduction reported by participants. However, other measures related to sleep quality, depression, cognitive function, and inflammatory markers did not show similar significant changes.
Importantly, we found that the vitamin D group reported no serious adverse effects, indicating that this supplementation is generally safe. These findings suggest that high-dose vitamin D may offer substantial benefits for anxiety relief in patients recovering from COVID-19, albeit with limited effects on other symptoms.
Read More
8
Vitamin D mitigates anxiety symptoms
Placenta-specific CYP11A1 overexpression lead to autism-like symptom in offspring with altered steroid hormone biosynthesis in the placenta-brain axis and rescued by vitamin D intervention.
Strong relevance to vitamin D effects
We explored the impact of changing levels of a specific enzyme, CYP11A1, in the placenta and how it might influence anxiety and social behavior in offspring. Using a unique mouse model, we found that higher levels of this enzyme are associated with behaviors similar to those seen in autism spectrum disorders (ASD), such as reduced social interaction and increased anxiety.
Interestingly, we observed that these anxiety-related behaviors improved significantly after administering vitamin D3. Behavioral tests, including open field and elevated plus maze assessments, showed that the mice exhibited less anxiety when given this supplement.
Additionally, our study highlighted that vitamin D3 could help correct some of the hormonal imbalances linked to CYP11A1 overexpression. Higher progesterone levels and increased inflammation were noted in the affected mice, and these issues seemed to reverse with vitamin D3 treatment.
This research underscores not only the potential role of vitamin D in managing anxiety but also suggests that examining CYP11A1 levels could be important for understanding and perhaps preventing some neurodevelopmental disorders. Overall, it appears vitamin D3 may serve as a useful tool in mitigating anxiety linked to hormonal changes during development.
Interestingly, we observed that these anxiety-related behaviors improved significantly after administering vitamin D3. Behavioral tests, including open field and elevated plus maze assessments, showed that the mice exhibited less anxiety when given this supplement.
Additionally, our study highlighted that vitamin D3 could help correct some of the hormonal imbalances linked to CYP11A1 overexpression. Higher progesterone levels and increased inflammation were noted in the affected mice, and these issues seemed to reverse with vitamin D3 treatment.
This research underscores not only the potential role of vitamin D in managing anxiety but also suggests that examining CYP11A1 levels could be important for understanding and perhaps preventing some neurodevelopmental disorders. Overall, it appears vitamin D3 may serve as a useful tool in mitigating anxiety linked to hormonal changes during development.
Read More
8
Link between Vitamin D and anxiety
Association of serum vitamin D with anxiety in US adults: a cross-sectional study.
High relevance for vitamin D research
We examined if there is a connection between vitamin D levels and anxiety among US adults, utilizing data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2007 and 2012. The study included over 12,000 participants and employed sophisticated statistical methods to determine the relationship between serum vitamin D and anxiety.
Our analyses revealed that higher levels of serum vitamin D were associated with a lower risk of experiencing anxiety. Specifically, we found a significant inverse relationship; as vitamin D levels increased, the likelihood of anxiety decreased. This connection remained strong even after adjusting for various factors that could influence the results.
Furthermore, smooth curve fitting techniques confirmed a negative association between vitamin D and anxiety risk. Nonetheless, while these findings are promising, we emphasize the need for further prospective studies to validate these results and fully understand the implications of vitamin D on mental health.
Our analyses revealed that higher levels of serum vitamin D were associated with a lower risk of experiencing anxiety. Specifically, we found a significant inverse relationship; as vitamin D levels increased, the likelihood of anxiety decreased. This connection remained strong even after adjusting for various factors that could influence the results.
Furthermore, smooth curve fitting techniques confirmed a negative association between vitamin D and anxiety risk. Nonetheless, while these findings are promising, we emphasize the need for further prospective studies to validate these results and fully understand the implications of vitamin D on mental health.
Read More
8
Probiotics and vitamin D treatment
Probiotics plus vitamin D in irritable bowel syndrome: a prospective multicentric non-interventional study.
Limited insight on vitamin D
We evaluated the effectiveness of a treatment combining probiotics and vitamin D on patients suffering from irritable bowel syndrome, particularly focusing on those who experience anxiety. The study involved adult participants diagnosed with diarrhea-predominant IBS or mixed bowel movements, who took a daily sachet containing specific probiotic strains and vitamin D for 42 days.
At the end of the treatment period, we saw that a significant percentage of patients reported relief from their symptoms. Specifically, many in the study reported a marked decrease in the severity of their IBS symptoms, which was linked to improved quality of life and reductions in both anxiety and depression scores.
However, while vitamin D was part of the treatment regimen, it was used alongside probiotics, making it challenging to pinpoint the individual effect of vitamin D alone on anxiety. Still, the findings suggest that the combination might beneficially impact gut-related anxiety among IBS patients.
At the end of the treatment period, we saw that a significant percentage of patients reported relief from their symptoms. Specifically, many in the study reported a marked decrease in the severity of their IBS symptoms, which was linked to improved quality of life and reductions in both anxiety and depression scores.
However, while vitamin D was part of the treatment regimen, it was used alongside probiotics, making it challenging to pinpoint the individual effect of vitamin D alone on anxiety. Still, the findings suggest that the combination might beneficially impact gut-related anxiety among IBS patients.
Read More
7
Vitamin D may reduce anxiety
Associations Between Early-Pregnancy Vitamin D Status and Postpartum Depressive and Anxiety Symptoms.
Relevant study on vitamin D
We investigated whether vitamin D levels during pregnancy could predict anxiety symptoms in new mothers. In a large cohort study involving over 2,400 participants, we measured maternal serum vitamin D and C-reactive protein (CRP) levels around the 13-week mark of gestation. After giving birth, we checked in on the mothers three months later to assess their levels of depression and anxiety using standardized questionnaires.
Our findings suggest that insufficient vitamin D, particularly in women who did not take supplements, is linked to increased anxiety symptoms post-delivery. Specifically, a deficiency in vitamin D was associated with a noticeable rise in these symptoms, hinting that proper vitamin D levels might play a protective role. However, we found that CRP did not seem to mediate this relationship.
Overall, our research indicates that ensuring adequate vitamin D levels during pregnancy may be beneficial for reducing anxiety, especially for those not using supplements. Still, further clinical trials are needed to confirm whether vitamin D supplementation can actively mitigate postpartum affective disorders.
Our findings suggest that insufficient vitamin D, particularly in women who did not take supplements, is linked to increased anxiety symptoms post-delivery. Specifically, a deficiency in vitamin D was associated with a noticeable rise in these symptoms, hinting that proper vitamin D levels might play a protective role. However, we found that CRP did not seem to mediate this relationship.
Overall, our research indicates that ensuring adequate vitamin D levels during pregnancy may be beneficial for reducing anxiety, especially for those not using supplements. Still, further clinical trials are needed to confirm whether vitamin D supplementation can actively mitigate postpartum affective disorders.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.6
9.5
Remarkable anxiety relief
A True Game-Changer. These vitamins have drastically improved my life! I suffered from severe anxiety, among other symptoms, but noticed a remarkable difference within 1-1.5 weeks of taking them. My energy level increased and all unpleasant symptoms seemed to fade, including my anxiety surrounding driving. I continue to take a higher dosage because I noticed a negative difference with lesser brands. I am so grateful to have discovered these vitamins and will ensure I never run out!
Read More
9.5
Anxiety relief observed
Noticeable difference! I purchased this for my teenage daughter, who began experiencing panic and anxiety. After 30 days of use, there was a significant improvement. She expressed her gratitude, and we now have them on subscribe and save.
8.8
Improved sleep quality
Excellent, particularly for black men! I purchase these for my family along with Adam Now multis and Omegavia fish oil pills. Black men often have low Vitamin D levels unless they work in the sun. My brother struggled with insomnia and anxiety, but this, along with Calm Magnesium, significantly improved his sleep and daytime energy. He stopped once his D levels normalised and fell back into the same issues. A cheaper brand didn't help, making this a staple in our household. Most people are deficient, particularly the elderly and those with specific health issues, so I see no reason to stop using it. My ex, fit and healthy, was often tired and irritable with low testosterone but found these beneficial alongside his prescription.
Read More
