Last update
3/17/2026

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.3
USERS' SCORE
Good
Based on 12 Reviews
8.1
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Thiamin (B1 from culture of S.cerevisiae)
5 mg
417%
Riboflavin (B2 from culture of S. cerevisiae)
10 mg 
769%
Niacin (as Niacinamide from culture of S. cerevisiae)
45 mg 
281%
Vitamin B6 (from culture of S. cerevisiae)
10 mg 
588%
Folate (from culture of S. cerevisiae)
450 mcg DFE
113%
Vitamin B12 (as Methylcobalamin from culture of S. cerevisiae)
133 mcg 
5542%
Biotin (from culture of S. cerevisiae)
325 mcg 
1083%
Pantothenic Acid (from culture of S. cerevisiae)
45 mg
900%
RAW Organic Fruit & Vegetable Blend
360 mg
+
RAW Probiotic & Enzyme Blend
60 mg
+
📅 Last updated:

Top Medical Research Studies

8
Niacin helps alleviate anxiety symptoms
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.

Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Read More
8
We explored how vitamin B could help fight anxiety and depression linked to nicotine withdrawal in young male rats.

The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.

The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
Read More
7
Vitamin B may alleviate anxiety symptoms
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.

The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
Read More

Most Useful Reviews

9
Enhanced stress handling
23 people found this helpful
I felt a noticeable difference with these vitamins. They provided me with energy and alleviated my stress and anxiety. I initially bought them due to articles indicating that stress can arise from a vitamin B deficiency. With these, I managed stress much better, even after a promotion that brought increased pressure. They proved to be miraculous pills, also positively affecting my acne. Although a bit pricey, they are worth it.
Read More
9
Reduced work stress
16 people found this helpful
I feel good, and I knew that I would! I'm so glad I decided to take this. I noticed a difference from day one; the anxiety and stress I felt at work has disappeared. My hair is falling out less, looks healthier, and I have more energy. There’s also a reduction in my appetite—no more mindless eating, all with just one pill since I was already using a multivitamin. I’ve recommended this to my mum and sister, hoping it works for them too!
Read More
9
Promotes calmness
9 people found this helpful
Vitamin B has a positive impact on nerves, reducing anxiety and restoring mood. Garden of Life offers excellent complexes without synthetic additives. Their natural approach means their products are more costly, but they are worth the investment for health and well-being.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.3
  • All Researches
8
Niacin helps alleviate anxiety symptoms
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.

Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Read More
8
We explored how vitamin B could help fight anxiety and depression linked to nicotine withdrawal in young male rats.

The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.

The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
Read More
7
Vitamin B may alleviate anxiety symptoms
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.

The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
Read More
7
Vitamin B aids anxiety recovery
We explored the effects of vitamin B supplementation on anxiety and cognitive function in male Swiss albino mice following traumatic brain injury (TBI). Our research found that vitamin B appears to improve neurological impairments, enhance memory, and reduce anxiety-like behaviors.

Additionally, we saw a reduction in oxidative stress markers, indicating better neuronal health. This suggests that vitamin B not only helps with anxiety but also plays a role in recovery from cognitive dysfunctions associated with TBI.
Read More
7
No significant anxiety improvement
We explored the effectiveness of vitamin B complex in treating anxiety among patients with Post-COVID-19 syndrome (PC19S) through the PreVitaCOV trial. This study involved 240 participants who were given either prednisolone, vitamin B1, B6, and B12, a combination of these treatments, or a placebo. While the trial showed high feasibility and safety, it ultimately did not demonstrate significant benefits in symptom change over placebo in anxiety or other evaluated symptoms.
Read More

User Reviews

USERS' SCORE
Good
Based on 12 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Enhanced stress handling
23 people found this helpful
I felt a noticeable difference with these vitamins. They provided me with energy and alleviated my stress and anxiety. I initially bought them due to articles indicating that stress can arise from a vitamin B deficiency. With these, I managed stress much better, even after a promotion that brought increased pressure. They proved to be miraculous pills, also positively affecting my acne. Although a bit pricey, they are worth it.
Read More
9
Reduced work stress
16 people found this helpful
I feel good, and I knew that I would! I'm so glad I decided to take this. I noticed a difference from day one; the anxiety and stress I felt at work has disappeared. My hair is falling out less, looks healthier, and I have more energy. There’s also a reduction in my appetite—no more mindless eating, all with just one pill since I was already using a multivitamin. I’ve recommended this to my mum and sister, hoping it works for them too!
Read More
9
Promotes calmness
9 people found this helpful
Vitamin B has a positive impact on nerves, reducing anxiety and restoring mood. Garden of Life offers excellent complexes without synthetic additives. Their natural approach means their products are more costly, but they are worth the investment for health and well-being.
Read More
0
Worsened anxiety symptoms
2 people found this helpful
Disappointing! I love Garden of Life vitamins, but these caused a reaction. I developed a rash, and my moods worsened instead of improving. I was hopeful they would help with my anxiety, but now I’m stuck with an almost full bottle.
Read More
9
Effective anxiety relief
I began taking these vitamins to manage my anxiety, and they have worked wonders, significantly stabilising my mood swings.
Read More

Frequently Asked Questions

7.5
Reduced anxiety
1 people found this helpful
I decided to take a raw vitamin complex due to my deficiencies in B12 and B9. I take one tablet an hour after lunch and have noticed results within a week. I'm experiencing less anxiety and stress.
9
Effective anxiety relief
I began taking these vitamins to manage my anxiety, and they have worked wonders, significantly stabilising my mood swings.
9
Reduced anxiety issues
This excellent B complex, extracted from raw fruits and vegetables, along with probiotics, has significantly boosted my energy levels. I've noticed a marked reduction in anxiety, allowing me to remain calm in various situations.
7
Vitamin B may alleviate anxiety symptoms
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.

The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
8
Niacin helps alleviate anxiety symptoms
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.

Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
7
Vitamin B aids anxiety recovery
We explored the effects of vitamin B supplementation on anxiety and cognitive function in male Swiss albino mice following traumatic brain injury (TBI). Our research found that vitamin B appears to improve neurological impairments, enhance memory, and reduce anxiety-like behaviors.

Additionally, we saw a reduction in oxidative stress markers, indicating better neuronal health. This suggests that vitamin B not only helps with anxiety but also plays a role in recovery from cognitive dysfunctions associated with TBI.
7
No significant anxiety improvement
We explored the effectiveness of vitamin B complex in treating anxiety among patients with Post-COVID-19 syndrome (PC19S) through the PreVitaCOV trial. This study involved 240 participants who were given either prednisolone, vitamin B1, B6, and B12, a combination of these treatments, or a placebo. While the trial showed high feasibility and safety, it ultimately did not demonstrate significant benefits in symptom change over placebo in anxiety or other evaluated symptoms.
7
Diet impacts mood, not blood markers
We examined how the Swank and Wahls diets, along with vitamin B and folate supplements, influenced anxiety and mood in individuals with relapsing-remitting multiple sclerosis. Over 24 weeks, we observed notable improvements in mood from both dietary approaches evaluated with standard anxiety and depression scales.

However, these mood enhancements didn’t correlate with changes in serum levels of vitamin B, folate, or homocysteine. Simply put, while the diets helped improve mood, they did not do so by altering these blood markers.

References

  1. Chen J, Liu J, Zhang P, Zhang S. [Effects of Vitamin B on Behaviors, Brain Monoamine Neurotransmitters, and Brain-Derived Neurotrophic Factor in Depressive Rats]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2025;56:206. 10.12182/20250160608
  2. Samad N, Hameed A, Manzoor N, Shoukat S, Irfan A, et al. Antioxidant and neuro-modulatory effects of niacin prevent D-galactose-induced behavioral deficits and memory impairment. Exp Gerontol. 2024;198:112624. 10.1016/j.exger.2024.112624
  3. Yadav P, Nasir F, Sivanandam TM. Neuroprotective effect of vitamin B supplementation on cognitive functions and neuronal morphology at different time intervals after traumatic brain injury in male Swiss albino mice. Neurochem Int. 2024;180:105869. 10.1016/j.neuint.2024.105869
  4. Tengelmann C, Joos S, Kaußner Y, Malzahn U, Lunden L, et al. Feasibility, safety and effectiveness of prednisolone and vitamin B1, B6, and B12 in patients with post-COVID-19-syndrome (PreVitaCOV) - protocol of a randomised, double-blind, placebo-controlled multicentre trial in primary care (phase IIIb). BMC Infect Dis. 2024;24:56. 10.1186/s12879-023-08925-2
  5. Pahlavani H, Masoudi M, Khoshroo N, Kakhki S, Mahdi Rezavanimehr M, et al. Vitamin B reversed anxiety and depression induced by adolescent nicotine withdrawal through alteration the inflammatory, oxidative and serotoninergic profiles in male rats. Biochem Pharmacol. 2023;217:115832. 10.1016/j.bcp.2023.115832
  6. Kakhki S, Goodarzi M, Abbaszade-Cheragheali A, Rajabi M, Masoumipour AH, et al. Folic acid supplementation improved cognitive deficits associated with lithium administration during pregnancy in rat offspring. Int J Dev Neurosci. 2023;83:615. 10.1002/jdn.10289
  7. Shemirani F, Titcomb TJ, Saxby SM, Eyck PT, Rubenstein LM, et al. Association of serum homocysteine, folate, and vitamin B and mood following the Swank and Wahls elimination dietary interventions in relapsing-remitting multiple sclerosis: Secondary analysis of the WAVES trial. Mult Scler Relat Disord. 2023;75:104743. 10.1016/j.msard.2023.104743
Data last updated:
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