Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 28 Reviews
8.1
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Calcium (from Calcium-Magnesium Inositol Hexaphosphate)
100 mg
8%
Inositol Hexaphosphate (from Calcium-Magnesium Inositol Hexaphosphate)
500 mg
†
Top Medical Research Studies
9
We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability.
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Read More
9
We investigated how isogarcinol (ISO) influences breast cancer cells and what mechanisms are at play. Through lab tests, we found that ISO at 13 μM effectively lowered cell growth and movement. In living subjects, doses of 5 to 15 mg/kg showed a significant reduction in tumor activity.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
Read More
7
Vitamin E Succinate enhances autophagy
We examined how vitamin E succinate (VES) affects autophagy in human gastric cancer cells by activating a calcium signaling pathway. Our study involved cultured gastric cancer cell lines treated with various doses of VES. We noted that VES significantly reduced cell proliferation and enhanced the formation of autophagosomes, indicating increased autophagy.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
Read More
Most Useful Reviews
9
Significant cancer support
48 people found this helpful
IP6 is an incredible supplement, significantly reducing the formation of harmful AGEs that damage our organs and contribute to diabetes complications. Its ability to lower these substances by a remarkable 40% is impressive. I recommend taking it before meals for optimal effects. IP6 is also a powerful anti-cancer agent. For those with diabetes and insulin resistance, I've found it synergistic with other supplements and providing substantial overall protection and energy boost.
Read More
9
Top anti-cancer choice
18 people found this helpful
IP6 is my top anti-cancer supplement. It’s crucial to take it with distilled water, well away from food or other supplements. I find it most effective when taken first thing in the morning.
Read More
9
Cat cancer recovery
10 people found this helpful
My two cats faced sudden health crises with bladder stones and kidney failure. I discovered inositol, which I added to their food. One cat has regained her appetite and is now comfortable at home, astonishing the vet with her recovery. Regular blood tests show normal results now, and I plan to continue using it. I also intend to take it myself, believing it's beneficial for anyone over 40.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
- All Researches
9
We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability.
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Read More
9
We investigated how isogarcinol (ISO) influences breast cancer cells and what mechanisms are at play. Through lab tests, we found that ISO at 13 μM effectively lowered cell growth and movement. In living subjects, doses of 5 to 15 mg/kg showed a significant reduction in tumor activity.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
Read More
7
Vitamin E Succinate enhances autophagy
We examined how vitamin E succinate (VES) affects autophagy in human gastric cancer cells by activating a calcium signaling pathway. Our study involved cultured gastric cancer cell lines treated with various doses of VES. We noted that VES significantly reduced cell proliferation and enhanced the formation of autophagosomes, indicating increased autophagy.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
Read More
User Reviews
USERS' SCORE
Good
Based on 28 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Significant cancer support
48 people found this helpful
IP6 is an incredible supplement, significantly reducing the formation of harmful AGEs that damage our organs and contribute to diabetes complications. Its ability to lower these substances by a remarkable 40% is impressive. I recommend taking it before meals for optimal effects. IP6 is also a powerful anti-cancer agent. For those with diabetes and insulin resistance, I've found it synergistic with other supplements and providing substantial overall protection and energy boost.
Read More
9
Top anti-cancer choice
18 people found this helpful
IP6 is my top anti-cancer supplement. It’s crucial to take it with distilled water, well away from food or other supplements. I find it most effective when taken first thing in the morning.
Read More
9
Cat cancer recovery
10 people found this helpful
My two cats faced sudden health crises with bladder stones and kidney failure. I discovered inositol, which I added to their food. One cat has regained her appetite and is now comfortable at home, astonishing the vet with her recovery. Regular blood tests show normal results now, and I plan to continue using it. I also intend to take it myself, believing it's beneficial for anyone over 40.
Read More
7.5
Slows cancer progression
9 people found this helpful
My husband uses this supplement to slow the progression of his prostate cancer, and it seems to be helping so far.
Read More
9
Effective cancer supplement
5 people found this helpful
IP6 is a great anti-cancer supplement!
Read More
Frequently Asked Questions
7.5
Cancer prevention aid
4 people found this helpful
I noticed positive effects from this product almost immediately. I take it primarily as a preventative against cancer and it has also helped with a rash I had.
7.5
Post-cancer precaution
7 people found this helpful
I've been taking IP6 for four years after my cancer surgery. While I’m unsure of its role, I’m still cancer-free and consider it a good preventive measure.
7.5
Strengthens immunity
Based on research, IP6 helps strengthen immunity, especially for those dealing with cancer. I believe this brand is a good choice.
7.5
Good for cancer
2 people found this helpful
The quality is excellent for my father, who has cancer. The ingredients are beneficial and the quantity is great for the price. He is 72 years old and the packaging is good.
9
Significant cancer support
48 people found this helpful
IP6 is an incredible supplement, significantly reducing the formation of harmful AGEs that damage our organs and contribute to diabetes complications. Its ability to lower these substances by a remarkable 40% is impressive. I recommend taking it before meals for optimal effects. IP6 is also a powerful anti-cancer agent. For those with diabetes and insulin resistance, I've found it synergistic with other supplements and providing substantial overall protection and energy boost.
7.5
Helps cancer prevention
2 people found this helpful
IP6 has been beneficial in addressing polycystic ovary syndrome (PCOS) and may also protect against cancer. After starting this treatment, my menstrual cycle normalised, and I believe it helps ovulation as well.
6
Iron detoxification
2 people found this helpful
I chose this product since IP-6 helps detoxify excess iron which cancer cells absorb, causing inflammation. I found that avoiding processed foods has improved intestinal health by reducing iron intake. It is reassuring to see that the product contains rice bran from Japan. I use it sparingly when consuming processed foods.
7.5
Fighting cancer
1 people found this helpful
Since it's good for cancer, I'm also planning to give it alongside beta-glucan to support my cat in her fight.
9
Top anti-cancer choice
18 people found this helpful
IP6 is my top anti-cancer supplement. It’s crucial to take it with distilled water, well away from food or other supplements. I find it most effective when taken first thing in the morning.
9
We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability.
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
7
Vitamin E Succinate enhances autophagy
We examined how vitamin E succinate (VES) affects autophagy in human gastric cancer cells by activating a calcium signaling pathway. Our study involved cultured gastric cancer cell lines treated with various doses of VES. We noted that VES significantly reduced cell proliferation and enhanced the formation of autophagosomes, indicating increased autophagy.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
9
We investigated how isogarcinol (ISO) influences breast cancer cells and what mechanisms are at play. Through lab tests, we found that ISO at 13 μM effectively lowered cell growth and movement. In living subjects, doses of 5 to 15 mg/kg showed a significant reduction in tumor activity.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
References
- Islam MJ, Muntaha S, Masum MM, Nowshin S, Salam S, et al. Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line. Asian Pac J Cancer Prev. 2024;25:4447. doi:10.31557/APJCP.2024.25.12.4447
- Wen XY, Cao MM, Zhang ZY, Xie N, Wei ZY, et al. [The role of endoplasmic reticulum IP(3)R calcium channel in vitamin E succinate induced autophagy of human gastric cancer cell]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2025;43:180. doi:10.3760/cma.j.cn121094-20240125-00037
- Zhang D, Chu Y, Li M, Du L. Isogarcinol Reduces MARS Levels and Deactivates the PI3K/AKT Pathway to Suppress the Malignant Properties of Breast Cancer Cells. Cell Biochem Biophys. 2025. doi:10.1007/s12013-025-01727-0
