Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 61 Researches
8.2
USERS' SCORE
Good
Based on 17 Reviews
8.2
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Proprietary Probiotic BlendLacticaseibacillus rhamnosus R0011Lactobacillus helvetius R0052Pediococcus acidilactici R1001Lacticaseibacillus casei R0215Bifidobacterium longum BB536Lactiplantibacillus plantarum R1012Bifidobacterium breve R0070Lactococcus lactis subsp. lactis R1058
131 mg (10 Billion CFU)
†
Top Medical Research Studies
9
We investigated the effectiveness of a combined probiotic treatment for young children suffering from food allergies that affected their skin and digestive systems. In a randomized controlled study involving 92 children, those taking the probiotics saw a notable decrease in allergy symptoms and a significant drop in immunoglobulin E levels—an antibody linked with allergic reactions.
After 21 days of treatment, skin issues improved, while gastrointestinal symptoms like bloating and discomfort were also reduced. Although some symptoms returned over the next five months, the overall health of the group remained significantly better compared to those who didn’t receive the treatment.
After 21 days of treatment, skin issues improved, while gastrointestinal symptoms like bloating and discomfort were also reduced. Although some symptoms returned over the next five months, the overall health of the group remained significantly better compared to those who didn’t receive the treatment.
Read More
8
We investigated the impact of a probiotic ice cream containing engineered bacteria on pollen allergies in mice. After sensitizing the mice, we treated them with this unique ice cream for four weeks. The results were promising! The ice cream significantly lowered serum IgE levels, which are linked to allergic reactions. Additionally, beneficial cytokines increased while the levels of a harmful cytokine decreased. Overall, our findings suggest that this probiotic ice cream could improve allergy responses, particularly with Th1 and Treg involvement.
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9
We investigated how Probio-M9, a probiotic found in human milk, affects food allergies in mice sensitized to ovalbumin (OVA). Our study showed that administering live Probio-M9 significantly lowered levels of allergy markers like specific IgE and histamine, which are key in allergic reactions.
Importantly, Probio-M9 also shifted immune responses towards a more balanced state, reducing allergy-related inflammation. The analysis revealed beneficial changes in gut bacteria and an increase in short-chain fatty acids, which play a role in maintaining health.
Overall, our results suggest that Probio-M9 could be a promising approach to prevent food allergies.
Importantly, Probio-M9 also shifted immune responses towards a more balanced state, reducing allergy-related inflammation. The analysis revealed beneficial changes in gut bacteria and an increase in short-chain fatty acids, which play a role in maintaining health.
Overall, our results suggest that Probio-M9 could be a promising approach to prevent food allergies.
Read More
Most Useful Reviews
9
Gluten tolerance
18 people found this helpful
I had a gluten intolerance that caused severe sickness when eating wheat. After using this product, I experience nearly no symptoms when I consume wheat. It's truly transformative—this product has practically saved my life!
Read More
9
Allergy relief
5 people found this helpful
A family member suffered from severe hay fever for decades. After using this product for six months, their symptoms almost disappeared. They remarked, "It's like a miracle." Food allergies have lessened, and they have regular bowel movements. It has become an essential item in our home.
Read More
9
Skin allergies help
1 people found this helpful
I've taken Jarrow Formulas EPS for over ten years. It significantly aids bowel function and I take two capsules on an empty stomach each morning. This product not only improves bowel movements but also helps with skin allergies. I’ve used it long-term for its beneficial effects.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 61 Researches
8.2
- All Researches
9.5
We sought to understand if Bifiform Kids, a probiotic, could help prevent respiratory infections in children with recurrent infections and gastrointestinal allergy symptoms. In our controlled trial with 92 children aged 4 to 5, those taking the probiotic showed a significant 3-fold reduction in respiratory infections compared to the control group.
After 21 days, there were notable immune system improvements, including an increase in protective IgA levels and a decrease in allergic IgE. These findings suggest that Bifiform Kids is effective for preventing respiratory infections in children facing allergic issues.
After 21 days, there were notable immune system improvements, including an increase in protective IgA levels and a decrease in allergic IgE. These findings suggest that Bifiform Kids is effective for preventing respiratory infections in children facing allergic issues.
Read More
9
We investigated how Probio-M9, a probiotic found in human milk, affects food allergies in mice sensitized to ovalbumin (OVA). Our study showed that administering live Probio-M9 significantly lowered levels of allergy markers like specific IgE and histamine, which are key in allergic reactions.
Importantly, Probio-M9 also shifted immune responses towards a more balanced state, reducing allergy-related inflammation. The analysis revealed beneficial changes in gut bacteria and an increase in short-chain fatty acids, which play a role in maintaining health.
Overall, our results suggest that Probio-M9 could be a promising approach to prevent food allergies.
Importantly, Probio-M9 also shifted immune responses towards a more balanced state, reducing allergy-related inflammation. The analysis revealed beneficial changes in gut bacteria and an increase in short-chain fatty acids, which play a role in maintaining health.
Overall, our results suggest that Probio-M9 could be a promising approach to prevent food allergies.
Read More
9
We investigated the effectiveness of a combined probiotic treatment for young children suffering from food allergies that affected their skin and digestive systems. In a randomized controlled study involving 92 children, those taking the probiotics saw a notable decrease in allergy symptoms and a significant drop in immunoglobulin E levels—an antibody linked with allergic reactions.
After 21 days of treatment, skin issues improved, while gastrointestinal symptoms like bloating and discomfort were also reduced. Although some symptoms returned over the next five months, the overall health of the group remained significantly better compared to those who didn’t receive the treatment.
After 21 days of treatment, skin issues improved, while gastrointestinal symptoms like bloating and discomfort were also reduced. Although some symptoms returned over the next five months, the overall health of the group remained significantly better compared to those who didn’t receive the treatment.
Read More
9
We explored how Lactobacillus rhamnosus DNA might affect allergic responses linked to Th2 polarization. Using a specific protocol in mice, we administered LR-DNA daily for five days and observed its impact on intestinal cells. The results showed that LR-DNA increased PD-L1 expression in these cells, which then helped trigger the death of Th2 cells.
Importantly, while we found promising effects, the study suggests that just the DNA from the probiotic—not the live bacteria—was effective in reducing allergic responses.
Importantly, while we found promising effects, the study suggests that just the DNA from the probiotic—not the live bacteria—was effective in reducing allergic responses.
Read More
9
We examined how probiotics, especially Lactobacillus rhamnosus, can improve treatments for food allergies through allergen-specific immunotherapy (FA-AIT). These helpful bacteria promote better immune responses, leading to increased tolerance. Clinical trials revealed that combining Lactobacillus rhamnosus with peanut immunotherapy led to better desensitization rates and positive immune changes.
While FA-AIT remains under study, integrating probiotics into these treatments appears promising for achieving lasting relief from allergies and improving patient well-being.
While FA-AIT remains under study, integrating probiotics into these treatments appears promising for achieving lasting relief from allergies and improving patient well-being.
Read More
User Reviews
USERS' SCORE
Good
Based on 17 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Gluten tolerance
18 people found this helpful
I had a gluten intolerance that caused severe sickness when eating wheat. After using this product, I experience nearly no symptoms when I consume wheat. It's truly transformative—this product has practically saved my life!
Read More
9
Allergy relief
5 people found this helpful
A family member suffered from severe hay fever for decades. After using this product for six months, their symptoms almost disappeared. They remarked, "It's like a miracle." Food allergies have lessened, and they have regular bowel movements. It has become an essential item in our home.
Read More
9
Skin allergies help
1 people found this helpful
I've taken Jarrow Formulas EPS for over ten years. It significantly aids bowel function and I take two capsules on an empty stomach each morning. This product not only improves bowel movements but also helps with skin allergies. I’ve used it long-term for its beneficial effects.
Read More
9
Erased allergies
I love it! After one month of using these probiotics, my allergies have significantly decreased, and I recovered from norovirus quickly. The only downside is taking four pills daily on an empty stomach, which requires a commitment, but I'd definitely buy it again.
Read More
7.5
Digestive improvement
26 people found this helpful
After taking Jarro-Dophilus EPS, I no longer need digestive aids. A friend with numerous allergies and digestive issues claims to eat things she couldn’t before. I tried it and now recommend it widely. I’ve stopped taking Absorb-Aid capsules after meals; just one Jarro-Dophilus EPS in the morning and at bedtime is sufficient.
Read More
Frequently Asked Questions
9
No allergic reactions
Great product! The quality is excellent, and the ingredients are well-selected. I experienced no allergies or negative reactions. The large package size lasts a long time, and the average capsule size is easy to take. After a week, I noticed improvements in bowel function and metabolism, and my nervous system felt better.
9
Allergy relief
5 people found this helpful
A family member suffered from severe hay fever for decades. After using this product for six months, their symptoms almost disappeared. They remarked, "It's like a miracle." Food allergies have lessened, and they have regular bowel movements. It has become an essential item in our home.
7.5
Sensitive bowels
1 people found this helpful
A friend recommended this for her husband with bowel movement sensitivity. After about two weeks of taking three tablets daily, he noticed considerable improvement in his allergies and digestion.
9
Gluten tolerance
18 people found this helpful
I had a gluten intolerance that caused severe sickness when eating wheat. After using this product, I experience nearly no symptoms when I consume wheat. It's truly transformative—this product has practically saved my life!
7.5
Better digestion
6 people found this helpful
I've noticed significant improvement in my digestion. When I take this with nettle, I experience fewer problems with allergies related to food.
7.5
Digestive improvement
26 people found this helpful
After taking Jarro-Dophilus EPS, I no longer need digestive aids. A friend with numerous allergies and digestive issues claims to eat things she couldn’t before. I tried it and now recommend it widely. I’ve stopped taking Absorb-Aid capsules after meals; just one Jarro-Dophilus EPS in the morning and at bedtime is sufficient.
9
Erased allergies
I love it! After one month of using these probiotics, my allergies have significantly decreased, and I recovered from norovirus quickly. The only downside is taking four pills daily on an empty stomach, which requires a commitment, but I'd definitely buy it again.
7.5
Digestive support
3 people found this helpful
I have food allergies and can’t consume wheat. This product helps repair my digestive tract without causing any stomach issues. I recommend taking it on an empty stomach for optimal results.
7.5
Improved digestion
3 people found this helpful
This product is fantastic for those with food allergies, as it aids in digestion. It’s crucial to take on an empty stomach, and I have not experienced any stomach issues, such as gas or loose stools.
8
Life improvement
Due to allergies, I’ve had to give up dairy. I constantly take this probiotic, which undeniably regulates my digestive system, alleviates constipation and flatulence, greatly enhancing my quality of life. One package of 120 capsules lasts me a month.
7.5
Smooth defecation
Highly recommended! This product is very good, and I've repurchased it multiple times. My defecation has been smooth, and it has greatly helped improve my allergies.
8
We evaluated the impact of a specific blend of probiotics on allergic rhinitis symptoms through a carefully structured study involving a control group. Over a period of eight weeks, participants receiving probiotics reported notable improvements in their allergy-related quality of life.
Additionally, we observed beneficial changes in gut bacteria linked to reduced allergic responses. However, while the results were promising during treatment and shortly thereafter, the placebo group exhibited a worsening trend after the follow-up period, underscoring the probiotics’ potential role in managing allergic rhinitis effectively.
Additionally, we observed beneficial changes in gut bacteria linked to reduced allergic responses. However, while the results were promising during treatment and shortly thereafter, the placebo group exhibited a worsening trend after the follow-up period, underscoring the probiotics’ potential role in managing allergic rhinitis effectively.
9
We investigated how bifidobacterium lactis could help with food allergies in children by observing changes in specific immune cells. In our study, 256 children with food allergies were split into two groups: one received the treatment and the other a placebo, both for three months.
We noted a significant reduction in allergic symptoms and related markers in the treatment group compared to the placebo group. Additionally, results in a mouse model mirrored these findings, showing improved immune responses linked to beneficial cells. Overall, bifidobacterium lactis appears promising for managing food allergies.
We noted a significant reduction in allergic symptoms and related markers in the treatment group compared to the placebo group. Additionally, results in a mouse model mirrored these findings, showing improved immune responses linked to beneficial cells. Overall, bifidobacterium lactis appears promising for managing food allergies.
8
We investigated how Lactobacillus strains combined with oligosaccharides might combat food allergies. Through careful lab tests, we examined the growth and effectiveness of these combinations. The Lactiplantibacillus plantarum strain showed promise, surviving harsh stomach conditions and enhancing beneficial compounds.
Notably, when paired with fructo-oligosaccharides, it helped guide immune responses in a way that can reduce inflammation. Ultimately, the findings suggest this synbiotic mix could play a role in allergy management as a dietary supplement.
Notably, when paired with fructo-oligosaccharides, it helped guide immune responses in a way that can reduce inflammation. Ultimately, the findings suggest this synbiotic mix could play a role in allergy management as a dietary supplement.
References
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- Lungaro L, Malfa P, Manza F, Costanzini A, Valentini G, et al. Clinical Efficacy of Probiotics for Allergic Rhinitis: Results of an Exploratory Randomized Controlled Trial. Nutrients. 2024;16. doi:10.3390/nu16234173
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- Li L, Wen X, Gong Y, Chen Y, Xu J, et al. HMGN2 and Histone H1.2: potential targets of a novel probiotic mixture for seasonal allergic rhinitis. Front Microbiol. 2023;14:1202858. doi:10.3389/fmicb.2023.1202858
- Vasconcelos JA, Mota AS, Olímpio F, Rosa PC, Damaceno-Rodrigues N, et al. Lactobacillus rhamnosus Modulates Lung Inflammation and Mitigates Gut Dysbiosis in a Murine Model of Asthma-COPD Overlap Syndrome. Probiotics Antimicrob Proteins. 2025;17:588. doi:10.1007/s12602-023-10167-2
- Tan Lim CSC, Sajo MEJV, Orteza KEMP, Fernandez PBA, Vila MJC. Next-Gen biotherapeutics: A systematic review and network meta-analysis on postbiotics as treatment for pediatric atopic dermatitis. Pediatr Allergy Immunol. 2023;34:e14022. doi:10.1111/pai.14022
- Komulainen M, Saros L, Vahlberg T, Nermes M, Jartti T, et al. Maternal fish oil and/or probiotics intervention: Allergic diseases in children up to two years old. Pediatr Allergy Immunol. 2023;34:e14004. doi:10.1111/pai.14004
- Hou Y, Zheng S, Zou F, Wang D, Da H, et al. Lactobacillus rhamnosus 76 alleviates airway inflammation in ovalbumin-allergic mice and improves mucus secretion by down-regulating STAT6/SPDEF pathway. Immunobiology. 2023;228:152712. doi:10.1016/j.imbio.2023.152712
- Lee JY, Park JY, Jeong Y, Kang CH. Anti-Inflammatory Response in TNFα/IFNγ-Induced HaCaT Keratinocytes and Probiotic Properties of MG4644, MG4693, and MG5474. J Microbiol Biotechnol. 2023;33:1039. doi:10.4014/jmb.2301.01028
- Li D, Sorkhabi S, Cruz I, Foley PL, Bellanti JA. Studies of methylated CpG ODN from subsp. in a murine model: Implications for treatment of human allergic disease. Allergy Asthma Proc. 2025;46:e13. doi:10.2500/aap.2025.46.240100
- Jeong K, Jang SW, Jeon SA, Seo HJ, Kang SH, et al. Efficacy of and (NVP-1703) in Children With Allergic Rhinitis: A Randomized Controlled Trial. J Korean Med Sci. 2024;39:e266. doi:10.3346/jkms.2024.39.e266
- Niu X, Yin X, Wu X, Zhang Q, Jiang Y, et al. Heat-Killed BBMN68 in Pasteurized Yogurt Alleviates Mugwort Pollen-Induced Allergic Airway Responses through Gut Microbiota Modulation in a Murine Model. Foods. 2023;12. doi:10.3390/foods12102049
- Feíto-Rodríguez M, Ramírez-Boscà A, Vidal-Asensi S, Fernández-Nieto D, Ros-Cervera G, et al. Randomized double-blind placebo-controlled clinical trial to evaluate the effect of a mixture of probiotic strains on symptom severity and use of corticosteroids in children and adolescents with atopic dermatitis. Clin Exp Dermatol. 2023;48:495. doi:10.1093/ced/llad007
- Fang Z, Pan T, Li L, Wang H, Zhu J, et al. mediated tryptophan metabolism to improve atopic dermatitis via the gut-skin axis. Gut Microbes. 2022;14:2044723. doi:10.1080/19490976.2022.2044723
- Santos SS, Miranda VC, Trindade LM, Cardoso VN, Reis DC, et al. Bifidobacterium longum subsp. longum 5 Attenuates Signs of Inflammation in a Murine Model of Food Allergy. Probiotics Antimicrob Proteins. 2023;15:63. doi:10.1007/s12602-021-09846-9
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- Tan-Lim CSC, Esteban-Ipac NAR, Mantaring JBV, Chan Shih Yen E, Recto MST, et al. Comparative effectiveness of probiotic strains for the treatment of pediatric atopic dermatitis: A systematic review and network meta-analysis. Pediatr Allergy Immunol. 2021;32:124. doi:10.1111/pai.13305
- Wang H, He Y, Dang D, Feng L, Huang L, et al. subsp. CCFM1274 relieved allergic asthma symptoms by modifying intestinal tryptophan metabolism in mice. Food Funct. 2024;15:8810. doi:10.1039/d4fo01079e
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- Bezruk VV, Godovanets OS, Buriak OH, Voytkevich NI, Makarova OV, et al. The use of hydrolyzed formulas as a method of correction of feeding and clinical rehabilitation of infants with atopy signs. J Med Life. 2022;15:1536. doi:10.25122/jml-2022-0254
- Shikh EV, Drozdov VN, Vorobieva OA, Zhukova OV, Ermolaeva AS, et al. [The effectiveness of BIFIFORM KIDS in the prevention of the incidence of acute respiratory infections in children]. Vopr Pitan. 2022;91:97. doi:10.33029/0042-8833-2022-91-4-97-106
- Uwaezuoke SN, Ayuk AC, Eze JN, Odimegwu CL, Ndiokwelu CO, et al. Postnatal probiotic supplementation can prevent and optimize treatment of childhood asthma and atopic disorders: A systematic review of randomized controlled trials. Front Pediatr. 2022;10:956141. doi:10.3389/fped.2022.956141
- Anania C, Di Marino VP, Olivero F, De Canditiis D, Brindisi G, et al. Treatment with a Probiotic Mixture Containing Subsp. BB12 and L3 for the Prevention of Allergic Rhinitis Symptoms in Children: A Randomized Controlled Trial. Nutrients. 2021;13. doi:10.3390/nu13041315
- Tan-Lim CSC, Esteban-Ipac NAR, Recto MST, Castor MAR, Casis-Hao RJ, et al. Comparative effectiveness of probiotic strains on the prevention of pediatric atopic dermatitis: A systematic review and network meta-analysis. Pediatr Allergy Immunol. 2021;32:1255. doi:10.1111/pai.13514
- Bergmann KC, Krause L, Hiller J, Becker S, Kugler S, et al. First evaluation of a symbiotic food supplement in an allergen exposure chamber in birch pollen allergic patients. World Allergy Organ J. 2021;14:100494. doi:10.1016/j.waojou.2020.100494
- Schmidt RM, Pilmann Laursen R, Bruun S, Larnkjaer A, Mølgaard C, et al. Probiotics in late infancy reduce the incidence of eczema: A randomized controlled trial. Pediatr Allergy Immunol. 2019;30:335. doi:10.1111/pai.13018
- Liu Q, Jing W, Wang W. Ameliorates the Risk of Food Allergy in Chinese Children by Affecting Relative Percentage of Treg and Th17 Cells. Can J Infect Dis Med Microbiol. 2018;2018:4561038. doi:10.1155/2018/4561038
- Lee MF, Chen YH, Chiang CH, Wu CS, Li MH, et al. Oral Administration of Expressing Mite and Cockroach Major Allergens Alleviates Progression of Atopic March in a Mouse Model. Allergy Asthma Immunol Res. 2024;16:520. doi:10.4168/aair.2024.16.5.520
- Nakagawa R, Gu W, Mizobuchi H, Kodera S, Takano T, et al. subsp. YRC3780 modifies function of mesenteric lymph node dendritic cells to modulate the balance of T cell differentiation inducing regulatory T cells. Front Immunol. 2024;15:1395380. doi:10.3389/fimmu.2024.1395380
- Lee MF, Wang NM, Chen YH, Wu CS, Lee MH, et al. An atopic dermatitis-like murine model by skin-brushed cockroach Per a 2 and oral tolerance induction by Lactococcus lactis-derived Per a 2. PLoS One. 2023;18:e0291162. doi:10.1371/journal.pone.0291162
- Baek J, Kim JH, Kim W. Potential Anti-Allergy and Immunomodulatory Properties of LB 1022 Observed In Vitro and in an Atopic Dermatitis Mouse Model. J Microbiol Biotechnol. 2023;33:823. doi:10.4014/jmb.2301.01019
- Baars T, van Esch B, van Ooijen L, Zhang Z, Dekker P, et al. Raw milk kefir: microbiota, bioactive peptides, and immune modulation. Food Funct. 2023;14:1648. doi:10.1039/d2fo03248a
- Lee DH, Park HK, Lee HR, Sohn H, Sim S, et al. Immunoregulatory effects of Lactococcus lactis-derived extracellular vesicles in allergic asthma. Clin Transl Allergy. 2022;12:e12138. doi:10.1002/clt2.12138
- Lee MF, Chiang CH, Lin SJ, Wu CS, Chen YH. Effectiveness and safety of oral lactococci-based vaccine encoding triple common allergens to prevent airway allergy in mice. PLoS One. 2021;16:e0261333. doi:10.1371/journal.pone.0261333
- El Mecherfi KE, Lupi R, Cherkaoui M, Albuquerque MAC, Todorov SD, et al. Fermentation of Gluten by Lactococcus lactis LLGKC18 Reduces its Antigenicity and Allergenicity. Probiotics Antimicrob Proteins. 2022;14:779. doi:10.1007/s12602-021-09808-1
- Zhang K, Mirza WA, Ni P, Yu M, Wang C, et al. Recombination Lactococcus lactis expressing Helicobacter pylori neutrophil-activating protein A attenuates food allergy symptoms in mice. FEMS Microbiol Lett. 2021;368. doi:10.1093/femsle/fnab034
- Cervantes-García D, Jiménez M, Rivas-Santiago CE, Gallegos-Alcalá P, Hernández-Mercado A, et al. Lactococcus lactis NZ9000 Prevents Asthmatic Airway Inflammation and Remodelling in Rats through the Improvement of Intestinal Barrier Function and Systemic TGF-β Production. Int Arch Allergy Immunol. 2021;182:277. doi:10.1159/000511146
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