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SCIENTIFIC SCORE
Possibly Effective
Based on 54 Researches
7.4
USERS' SCORE
Good
Based on 7 Reviews
8.8
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Proprietary Probiotic BlendLacticaseibacillus rhamnosus R0011Lactobacillus helvetius R0052Pediococcus acidilactici R1001Lacticaseibacillus casei R0215Bifidobacterium longum BB536Lactiplantibacillus plantarum R1012Bifidobacterium breve R0070Lactococcus lactis subsp. lactis R1058
131 mg (10 Billion CFU)
†
Top Medical Research Studies
8
Lactobacillus JB-1 reduces anxiety
Continuous Ingestion of JB-1 during Chronic Stress Ensures Neurometabolic and Behavioural Stability in Rats.
Study indicates probiotic benefits
We explored how the treatment with JB-1—a type of probiotic bacteria—affects anxiety during chronic stress in rats. In our study, half of the twenty rats received JB-1 while the other half got a placebo over eight weeks of stress exposure.
The results were telling! Rats on JB-1 showed less anxiety and were more willing to explore their environment compared to the placebo group, which largely avoided exploration. Additionally, measurements of brain metabolites indicated that JB-1 helped maintain stability in brain chemistry, even in stressful conditions.
This suggests that lactobacillus rhamnosus might play a beneficial role in reducing anxiety during prolonged stress.
The results were telling! Rats on JB-1 showed less anxiety and were more willing to explore their environment compared to the placebo group, which largely avoided exploration. Additionally, measurements of brain metabolites indicated that JB-1 helped maintain stability in brain chemistry, even in stressful conditions.
This suggests that lactobacillus rhamnosus might play a beneficial role in reducing anxiety during prolonged stress.
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8
Lactococcus lactis may reduce anxiety
In Vitro Probiotic and Antioxidant Potential of subsp. LL95 and Its Effect in Mice Behaviour.
Highly relevant findings on anxiety
We aimed to investigate how Lactococcus lactis subsp. LL95 affects anxiety and depression-like behaviors in mice. After administering LL95 orally for 28 days, we observed notable improvements in behavior. Mice showed less immobility in tests designed to measure depression and preferred open spaces, suggesting decreased anxiety levels. These findings highlight LL95's potential as a therapeutic probiotic, extending its benefits beyond gut health and showcasing its effects on mental well-being.
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9
Probiotic improves anxiety in mice
5-HT attenuates chronic stress-induced cognitive impairment in mice through intestinal flora disruption.
Moderate significance in findings
We examined how Lactococcus lactis E001-B-8 impacts anxiety in female mice under chronic stress conditions. Through a series of behavioral tests, we found that this probiotic not only helped improve cognitive function but also reduced anxiety-like behaviors.
Unlike traditional treatments like FLX, L. lactis was linked to better serotonin metabolism and healthier gut microbiome composition. This suggests that enhancing gut health could be a promising approach for anxiety management.
Unlike traditional treatments like FLX, L. lactis was linked to better serotonin metabolism and healthier gut microbiome composition. This suggests that enhancing gut health could be a promising approach for anxiety management.
Read More
Most Useful Reviews
9.5
Improved mood
Excellent! I suffered from mild depression and anxiety for a long time but struggled to find the right antidepressants until I started taking this. Initially, I wanted it for an energy and immunity boost, but now on my third bottle, my mood has significantly improved!
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8.8
Reduces tension
This product relieves stress and tension, reduces anxiety, and normalises the nervous system while improving blood circulation. It's been beneficial for me overall.
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7
Anxiety reduction
This product effectively reduces my anxiety.
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Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 54 Researches
7.4
9
Probiotics impact anxiety in AD
Ameliorative effects of probiotics in AlCl-induced mouse model of Alzheimer's disease.
High relevance in neurodegeneration
We investigated how probiotics, specifically Lactobacillus rhamnosus and Bifidobacterium BB-12, can affect anxiety in a mouse model of Alzheimer’s disease. In our study, we found that mice treated with these probiotics exhibited significantly reduced anxiety-like behaviors compared to those exposed to aluminum chloride alone.
Through various behavioral tests, it was evident that this probiotic combination also improved memory functions. Our results suggest that leveraging the gut-brain axis through these probiotics could offer a promising approach for alleviating anxiety and cognitive deficits in neurodegenerative conditions like Alzheimer's.
Through various behavioral tests, it was evident that this probiotic combination also improved memory functions. Our results suggest that leveraging the gut-brain axis through these probiotics could offer a promising approach for alleviating anxiety and cognitive deficits in neurodegenerative conditions like Alzheimer's.
Read More
9
Probiotic alleviates IBS-D symptoms
A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live CECT 7347 (ES1) and heat-treated CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome.
Highly relevant clinical findings
We conducted a study to assess how well the probiotic CECT 7347 (ES1) and the heat-treated version (HT-ES1) helped alleviate diarrhea-predominant irritable bowel syndrome (IBS-D) symptoms in adults. Over 84 days, participants took either the probiotic, the postbiotic, or a placebo, reporting significant improvement in key measures like symptom severity, quality of life, and even anxiety levels. The results demonstrated a notable reduction in IBS symptoms, making it one of the first trials to show such effectiveness in this area.
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9
Bifidobacterium longum may ease anxiety
Interactions between symptoms and psychological status in irritable bowel syndrome: An exploratory study of the impact of a probiotic combination.
Study shows promising probiotic effects.
We examined the impact of a probiotic blend, Bifidobacterium longum strains 1714® and 35642®, on anxiety and irritable bowel syndrome (IBS) symptoms in patients. Over eight weeks, we observed that the treatment helped restore the stress response and improved IBS symptoms and psychometric scores for anxiety and depression.
Interestingly, the benefits continued after stopping treatment, suggesting a lasting positive effect. The findings indicate that managing stress can significantly influence IBS symptoms and associated mood disturbances.
Interestingly, the benefits continued after stopping treatment, suggesting a lasting positive effect. The findings indicate that managing stress can significantly influence IBS symptoms and associated mood disturbances.
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9
Probiotics reduce anxiety in mice
Ameliorative effects of probiotics in AlCl-induced mouse model of Alzheimer's disease.
Highly relevant to Alzheimer's research
We explored how a combination of two probiotics, Lactobacillus rhamnosus GG and Bifidobacterium BB-12, affects anxiety in a mouse model of Alzheimer's disease. By conducting behavioral tests, we observed that probiotics significantly reduced anxiety-like behavior after exposure to aluminum chloride.
Furthermore, the treatment enhanced both spatial and recognition memory compared to the untreated group. Our findings illustrate that these probiotics can potentially alleviate anxiety and cognitive deficits linked with Alzheimer's disease through their influence on the gut-brain axis.
Furthermore, the treatment enhanced both spatial and recognition memory compared to the untreated group. Our findings illustrate that these probiotics can potentially alleviate anxiety and cognitive deficits linked with Alzheimer's disease through their influence on the gut-brain axis.
Read More
9
Bifidobacterium lactis reduces anxiety significantly
Bifidobacterium lactis Probio-M8 Adjuvant Treatment Confers Added Benefits to Patients with Coronary Artery Disease via Target Modulation of the Gut-Heart/-Brain Axes.
Highly relevant to gut-brain health
We conducted a thorough investigation into the effects of Bifidobacterium lactis, known as Probio-M8, on anxiety and overall well-being in patients with coronary artery disease (CAD). Over six months, we compared a group receiving the probiotic with a placebo group.
Notably, those in the probiotic group reported significant improvements in anxiety levels and other markers of mental health. This suggests that enhancing gut health can also positively influence our mood and emotional states.
With ongoing research, it’s becoming clearer how beneficial our gut bacteria can be for our overall mental and physical wellness.
Notably, those in the probiotic group reported significant improvements in anxiety levels and other markers of mental health. This suggests that enhancing gut health can also positively influence our mood and emotional states.
With ongoing research, it’s becoming clearer how beneficial our gut bacteria can be for our overall mental and physical wellness.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.8
9.5
Improved mood
Excellent! I suffered from mild depression and anxiety for a long time but struggled to find the right antidepressants until I started taking this. Initially, I wanted it for an energy and immunity boost, but now on my third bottle, my mood has significantly improved!
9.5
Gut health restored
This probiotic, along with kefir, truly saved my gut. After multiple rounds of antibiotics, my gut suffered significantly. However, this combination completely transformed my gut biome, and both my heartburn and anxiety symptoms disappeared in a week, despite the initial discomfort.
8.8
Supports immunity
Beneficial bacteria are essential for everyone, especially during travel, as they strengthen immunity. I advise those suffering from anxiety, fear, or weak immunity to take them regularly. Improvement is noticeable after consistent use, and using them on an empty stomach is best.
8.8
Helps anxiety
I experienced anxiety and irritability due to a stress-related ulcer. Since using this product, I’ve noticed improved stool consistency and reduced anxiety. I recommend it for those suffering similar issues.
8.8
Reduces tension
This product relieves stress and tension, reduces anxiety, and normalises the nervous system while improving blood circulation. It's been beneficial for me overall.
