Medical Researches
Moderately Effective
Based on 40 Researches
Probiotic-based cancer treatment strategyAnaerobic probiotics-in situ Se nanoradiosensitizers selectively anchor to tumor with immuno-regulations for robust cancer radio-immunotherapy.
High relevance to cancer therapies
We explored how a novel approach using bifidobacterium longum combined with selenium nanoparticles might improve cancer treatment. This method targets tumor cells in oxygen-poor environments to halt their growth, while simultaneously boosting the immune response against cancer.
The therapy not only damages tumor cells but also reduces the number of immunosuppressive cells in tumors. However, there is no significant mention of direct benefits in long-term cancer outcomes. This innovative strategy aims to enhance the efficacy of traditional radiotherapy, offering a promising avenue for future treatments.
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We explored the effects of probiotic bacteria and their metabolites on colorectal cancer (CRC) growth through a study comparing CRC patients with healthy individuals.
Our findings revealed that beneficial strains like Bifidobacterium longum were significantly less prevalent in CRC patients. We treated cancer organoid lines with metabolites from various bacteria, including Bifidobacterium longum, and observed a notable reduction in cancer growth.
This research emphasizes how the loss of beneficial bacteria and their metabolites could contribute to cancer development and showcases the potential of these metabolites in inhibiting CRC growth.
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Probiotics may enhance immunotherapyOral administration of Bifidobacterium longum and Bifidobacterium infantis ameliorates cefcapene pivoxil-induced attenuation of anti-programmed cell death protein-1 antibody action in mice.
Significant effect on treatment efficacy
We investigated how Bifidobacterium longum, alongside Bifidobacterium infantis, might enhance the effectiveness of cancer immunotherapy. In a mouse study, these probiotics were administered alongside an antibiotic known to undermine the action of cancer treatments.
Surprisingly, while the antibiotic alone led to increased tumor growth, the probiotics helped to improve the anti-tumor effects of the therapy. By altering gut bacteria and boosting certain immune responses, this suggests that probiotics could be a novel approach to enhance cancer treatment, especially for patients undergoing antimicrobial therapy.
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We examined the impact of probiotics on Helicobacter pylori eradication treatment. By analyzing data from 91 randomized controlled trials with nearly 13,700 participants, we found that adding probiotics significantly improved the eradication success rate.
Specifically, a strain called Bifidobacterium longum showed remarkable results, achieving an effectiveness rate of 81%. Beyond increasing effectiveness, probiotics also reduced common side effects such as nausea, diarrhea, and abdominal pain, making treatment more manageable.
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B. longum enhances liver recoveryBifidobacterium longum promotes postoperative liver function recovery in patients with hepatocellular carcinoma.
Significant relevance to cancer recovery
We explored how timely liver function recovery (LFR) impacts long-term survival in hepatocellular carcinoma (HCC) patients and discovered Bifidobacterium longum, which is linked to improved recovery. In our study, we found that transferring fecal microbiota from HCC patients with delayed recovery to mice affected their recovery. Remarkably, giving these mice B. longum sped up their liver repair. In a clinical trial, a probiotic cocktail with B. longum significantly lowered recovery delays and shortened hospital stays for HCC patients, ultimately boosting their one-year survival rates.
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User Reviews
Improved intestinal health
I am pleasantly surprised. After taking 2 or 3 tablets daily for ten days, I noticed positive changes. My usual morning stool now comes out around 2 pm. Previously, I experienced painful bloating after lunch, but that discomfort has disappeared, and my bowel movements are much smoother. After my mother died of colon cancer, I feared inheriting that issue, so I started this to improve my gut health. I look forward to continuing this and hope it will benefit both my intestinal and skin health over the next three months.
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Effective against constipation
I had high hopes for this probiotic after experiencing cancer previously. It effectively alleviates my severe constipation, and I noticed positive results within five years, even with just one a day. I will definitely repurchase!
Good effects of lactic acid bacteria. After taking it two hours post-meal, my constipation improved, which is a welcomed relief. I also heard that maintaining bowel health may reduce the recurrence of cancer.