We investigated the effects of Limosilactobacillus fermentum (L. fermentum) KBL674 on vaginal candidiasis in a mouse model. This strain inhibited the growth of Candida albicans and significantly decreased infection symptoms. Notably, the oral intake of L. fermentum KBL674 influenced both vaginal and gut microbiome health, promoting beneficial bacteria that seemed to correlate with reduced C. albicans levels. Thus, L. fermentum KBL674 shows promise for managing vaginal candidiasis by enhancing gut microbiome diversity and lowering fungal burden.
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9
Lactobacillus aids microbiota stability
Lactobacillus probiotics restore vaginal and gut microbiota of pregnant women with vaginal candidiasis.
We conducted a rigorous study to investigate the impact of lactobacillus probiotics on pregnant women suffering from vaginal candidiasis. In this double-blind, placebo-controlled trial involving 78 participants, we administered a probiotic for eight weeks.
Our results highlighted significant benefits, with the probiotics maintaining microbiota stability in the vagina and gut, unlike the placebo group. Participants taking probiotics showed less variation in their microbiota, which is crucial for overall health. While the treatment showed promise in preserving microbiota composition, individual experiences may vary.
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4
Lactobacillus shows promise for candidiasis
Efficacy and safety of Lactobacillus plantarum P 17630 strain soft vaginal capsule in vaginal candidiasis: a randomized non-inferiority clinical trial.
We assessed how well Lactobacillus plantarum P 17630 works against vaginal candidiasis compared to traditional antifungal treatments like miconazole. In a controlled trial, women with candidiasis took either Lactobacillus capsules or miconazole capsules for several days. Results showed that both treatments reduced vaginitis symptoms over time, with no significant differences. Importantly, Lactobacillus treatment did not lead to any adverse effects and may foster healthier vaginal flora in the long run, potentially decreasing recurring infections.
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Most Useful Reviews
10
Symptoms gone
Relief within 2 days! After suffering from Candidiasis-related issues for six months, I took four Jarrow Formulas, Jarro-Dophilus daily. Within two days, I felt better, and after about ten days, all my symptoms vanished, allowing me to enjoy a broader diet.
Read More
9.5
No Candidiasis issues
One of the best products I’ve used! I am on extended antibiotics for Lyme disease and have had no Candidiasis issues, all thanks to this supplement.
Read More
10
Best for IBS
Much better than any other products! This is perfect for Candidiasis issues and IBS. It has been the only product that relieved my constant diarrhoea since childhood, over 20 years ago! I highly recommend it to anyone facing similar digestive problems. Be patient, as it takes time to adjust your gut flora, but the relief from persistent belly pain is worth it.
This study looked at Lactobacillus gasseri VHProbi E09, a strain shown to effectively inhibit harmful bacteria like Gardnerella vaginalis and Candida albicans, key players in vaginitis. We found that this strain could cut the growth of both pathogens by an impressive 99%, while also preventing their attachment to vaginal cells.
What’s exciting is the potential of L. gasseri VHProbi E09 as a probiotic for improving vaginal health, either taken orally or applied directly. However, more research is needed to fully explore its effects and effectiveness in restoring balance in the vaginal ecosystem.
Through innovative techniques like genome-scale metabolic modeling and metagenomic sequencing, we discovered the role of specific lactobacillus strains in combating vulvovaginal candidiasis (VVC).
Our analysis of 159 strains showed that many have inhibitory effects on Candida, altering its metabolism through key metabolites like L-lactate and formate. Interestingly, we found a positive link between the presence of these beneficial strains and lower Candida levels in vaginal samples.
This research informs future strategies focused on enhancing vaginal health by utilizing these powerful strains and their metabolites to hinder candidiasis.
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9
AJCR4 displays antifungal promise
AJCR4: A Potential Probiotic in the Fight Against Oral spp. Biofilms.
We investigated the potential of a newly isolated probiotic, AJCR4, to combat oral candidiasis, a common infection, particularly among immunocompromised individuals. AJCR4 showed strong antifungal effects against both free and biofilm forms of Candida, with impressive results in reducing viable cells in lab tests. In specific biofilms, we observed over 2-log reductions in cell counts. This promising performance suggests that AJCR4 could serve as an effective alternative strategy for treating difficult oral candidiasis cases, especially recurrent infections.
Read More
9
Potential alternative for VVC treatment
Dual Mechanisms of Action: Anti-Candida and Anti-Inflammatory Potential of Fermentation Broth in Treating Vulvovaginal Candidiasis.
We investigated the effects of a novel fermentation broth called VAGINNE on vulvovaginal candidiasis (VVC), a common condition affecting many women. Using a mouse model, we found that VAGINNE not only boosted beneficial bacteria but also suppressed the growth of Candida, promoting a healthier vaginal environment.
Additionally, VAGINNE significantly decreased inflammation markers, which is essential for tissue health. This promising approach suggests VAGINNE could be a valuable alternative to traditional antifungals, especially for women facing drug resistance or side effects from standard treatments.
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9
Probiotics enhance candidiasis treatment
Role of Probiotic in Vulvovaginal Candidiasis: A Randomised Controlled Non-blinded Trial from India.
We explored how combining oral probiotics with standard antifungal treatment affects vulvovaginal candidiasis (VVC). In a randomized controlled trial involving 60 patients, we compared results between those receiving antifungal medication alone and those receiving it alongside probiotics.
The results were promising! Participants who took probiotics showed better clinical and mycological outcomes, along with a reduced rate of relapse compared to those on antifungal treatment alone. This suggests that probiotics may be a valuable addition to VVC management.
Relief within 2 days! After suffering from Candidiasis-related issues for six months, I took four Jarrow Formulas, Jarro-Dophilus daily. Within two days, I felt better, and after about ten days, all my symptoms vanished, allowing me to enjoy a broader diet.
Read More
9.5
No Candidiasis issues
One of the best products I’ve used! I am on extended antibiotics for Lyme disease and have had no Candidiasis issues, all thanks to this supplement.
Read More
10
Best for IBS
Much better than any other products! This is perfect for Candidiasis issues and IBS. It has been the only product that relieved my constant diarrhoea since childhood, over 20 years ago! I highly recommend it to anyone facing similar digestive problems. Be patient, as it takes time to adjust your gut flora, but the relief from persistent belly pain is worth it.
Read More
9.5
Fighting candida
Great job! This product is excellent for battling Candidiasis and enhancing digestion. Its affordability is also a significant factor.
Read More
10
Thrush relief
For a very long time, I struggled with thrush and tried nearly all suppositories and tablets. Thanks to this product, my issues are resolved, and my gastrointestinal tract is functioning normally! I highly recommend it.
Candidiasis, commonly known as a yeast infection, is an infection caused by the overgrowth of Candida, a type of fungus that naturally occurs in various locations in the body, including the mouth, gut, and vagina. Under normal circumstances, Candida exists in balance with other microorganisms, but factors such as antibiotic use, high sugar diets, and compromised immune systems can disrupt this balance, leading to an overgrowth. This can manifest in various forms, including oral thrush (affecting the mouth), vaginal yeast infections, and invasive candidiasis (which can affect the bloodstream and internal organs).
Symptoms of candidiasis vary depending on the area affected; for example, a vaginal yeast infection can cause itching, burning, and unusual discharge, while oral thrush may lead to white patches in the mouth, soreness, and difficulty swallowing. Treatment typically involves antifungal medications, which can be prescribed or obtained over-the-counter, depending on the severity and type of the infection. To prevent recurrence, it's essential to maintain a healthy diet, manage stress, and practice good hygiene. If you suspect you have candidiasis, particularly in more severe cases, consulting a healthcare provider is recommended for appropriate diagnosis and treatment options.
Lactobacillus is a genus of bacteria that plays a crucial role in the fermentation of various foods and is found naturally in the human gut. Known for their probiotic properties, strains of Lactobacillus are commonly utilized in the production of yogurt, sauerkraut, and other fermented products. They are characterized by their rod-shaped structure and ability to convert sugars into lactic acid, which not only helps preserve food but also contributes to the tangy flavor of fermented foods.
In addition to their culinary uses, Lactobacillus bacteria can offer several health benefits. They are known to support gut health by enhancing the balance of beneficial bacteria in the microbiome, potentially aiding in digestion and alleviating symptoms of issues like irritable bowel syndrome (IBS). Regular consumption of Lactobacillus-containing foods or supplements may also bolster the immune system and improve overall digestive health. With a growing interest in gut health, Lactobacillus remains a key player in both dietary and therapeutic contexts.
Research suggests that Lactobacillus, a genus of probiotic bacteria, may play a beneficial role in managing Candidiasis, a fungal infection caused by an overgrowth of Candida species, particularly Candida albicans. Probiotics like Lactobacillus can help maintain a healthy balance of vaginal flora, potentially inhibiting the growth of harmful organisms, including yeast. Studies have indicated that supplementation with Lactobacillus can help restore the natural microbiome, which may reduce the frequency and severity of candidiasis symptoms.
While incorporating Lactobacillus through dietary sources like yogurt, fermented foods, or probiotic supplements can support overall gut and vaginal health, it is essential to consult with a healthcare professional for personalized advice. Probiotics may not replace traditional antifungal treatments, but they may complement them and promote a more resilient microbiome. If you’re experiencing recurrent candidiasis, discussing the potential benefits of Lactobacillus with your healthcare provider can help you determine the best course of action.
Based on user reviews, the timeline for seeing results from this supplement for Candidiasis can vary. Some users report experiencing relief quite quickly; for example, one individual felt notable improvement within just two days of starting the Jarrow Formulas, Jarro-Dophilus, with symptoms completely vanishing after ten days (Read Review). Others, however, have noted that it might take longer to fully adjust and see the best results, with recommendations for patience as the gut flora stabilizes (Read Review).
Additionally, users highlight that while many find benefits soon after starting the supplement, consistent use over time typically enhances overall gut health and may lead to ongoing improvements in managing Candidiasis (Read Review). For instance, one user mentioned a noticeable enhancement in their condition after 1.5 months of use (Read Review). Overall, while some may find immediate benefits, others recommend allowing several weeks for optimal results.
The use of probiotics, particularly specific strains of Lactobacillus, is becoming an area of interest in the scientific community for managing candidiasis, particularly vulvovaginal candidiasis (VVC). Research indicates that various strains of Lactobacillus can inhibit the growth of Candida, promote a healthier vaginal microbiome, and reduce infection symptoms. For example, a study highlighted that Lactobacillus plantarum P 17630 showed effectiveness similar to traditional antifungal treatments without adverse effects, potentially preventing recurring infections [15]. Another study in a clinical trial context indicated that combining probiotics with standard antifungal treatments led to improved clinical outcomes and reduced relapse rates, further supporting the integration of probiotics into candidiasis management strategies [5].
Additionally, certain probiotic formulations, such as AJCR4, have demonstrated promising antifungal effects against oral candidiasis, indicating that these beneficial microorganisms may have applications beyond just VVC [3]. While some studies have shown mixed results in terms of overall effectiveness, particularly in preventing recurrence rates rather than outright eliminating infections, they do suggest that probiotics could be a valuable tool in managing Candida-related conditions [13]. Overall, the accumulating evidence suggests that when used appropriately, probiotics have a supporting role in the management of candidiasis, making them worth considering for those affected.
Users have reported a range of improvements in their symptoms after using the Jarrow Formulas, Jarro-Dophilus probiotics. Many testimonials highlight rapid relief from Candidiasis-related issues, with some individuals experiencing significant symptom reduction within days of starting the supplement. One user noted feeling better within just two days, with symptoms completely vanishing in ten days (Read Review). Others have shared their success stories of long-term management; for example, a user successfully managed their Candidiasis for five years while consistently using the product (Read Review).
In addition to alleviating symptoms, users have also reported improvements in their overall digestive health, with many finding relief from chronic issues such as IBS and persistent nausea or bloating. One user, who had struggled for over 20 years, stated that this probiotic was the only product that relieved their constant diarrhea (Read Review). Another mentioned feeling an immediate improvement when first taking the supplement (Read Review). Collectively, these anecdotal experiences suggest that while individual results can vary, many users have found significant benefits in managing Candidiasis and enhancing their digestive health.
Users have reported positive experiences when combining Jarrow Formulas, Jarro-Dophilus with other supplements or treatments for managing Candidiasis. For instance, one user mentioned that while on extended antibiotics for Lyme disease, they did not encounter any Candidiasis issues, attributing this success to the probiotics in their regimen, which helped balance their gut during antibiotic treatment (Read Review). Additionally, another user cited that they have been integrating these probiotics into a more complex treatment plan for Candidiasis, leading to noticeable improvements in their condition (Read Review).
Moreover, users frequently suggest patience and adherence to dosages when combining these probiotics with other treatments. One user noted that they had to increase their dosage from one to three capsules to experience substantial relief from Candidiasis symptoms, underlining the importance of adjusting intake based on individual response (Read Review). Overall, anecdotal evidence points toward the effectiveness of this probiotic in conjunction with other treatments, facilitating better management of Candidiasis and overall digestive health.
Based on user reviews, there appears to be a range of dosing strategies that individuals have successfully employed for treating Candidiasis with Lactobacillus probiotics. Many users reported effective results with around 4 capsules daily, as one user noted feeling improved within two days of taking four Jarrow Formulas, Jarro-Dophilus capsules daily, leading to complete symptom relief after ten days (Read Review). Others found success with a regimen of 2 capsules taken twice daily while recovering from IBS and Candidiasis overgrowth (Read Review).
Additionally, some users advocated for increases in dosage if initial results were not satisfactory. For example, one reviewer experienced no benefits from taking one capsule three times a day but noted significant improvement after upping their intake to three capsules three times a day (Read Review). Overall, users suggested that the right dose may vary, so experimenting within a reasonable range of 4 to 9 capsules daily could be beneficial, depending on individual responses.
10
Symptoms gone
Relief within 2 days! After suffering from Candidiasis-related issues for six months, I took four Jarrow Formulas, Jarro-Dophilus daily. Within two days, I felt better, and after about ten days, all my symptoms vanished, allowing me to enjoy a broader diet.
10
Best for IBS
Much better than any other products! This is perfect for Candidiasis issues and IBS. It has been the only product that relieved my constant diarrhoea since childhood, over 20 years ago! I highly recommend it to anyone facing similar digestive problems. Be patient, as it takes time to adjust your gut flora, but the relief from persistent belly pain is worth it.
9.5
Very helpful product
Jarrow Formulas, Jarro-Dophilus EPS, with 5 billion CFUs, has been extremely beneficial in managing my Candidiasis for five years.
8.8
Candidiasis improvement
Best Dophilus! Wonderful! I've been using these probiotics for 1.5 months, and they work fantastically. They keep me regular and have significantly reduced gas and bloating. I’ll certainly continue using them and recommending them to friends. I also noticed an improvement with my Candidiasis after taking EPS, which has outperformed Now GR-8.
8.8
Immediate relief
Dealing with Candidiasis overgrowth, this product makes me feel better immediately when I take it.
9.5
No Candidiasis issues
One of the best products I’ve used! I am on extended antibiotics for Lyme disease and have had no Candidiasis issues, all thanks to this supplement.
8.8
Improved indicators
Very good probiotics; I take them as part of a complex treatment for Candidiasis. I open the capsules, as my child cannot swallow them yet. However, after the first regimen, my indicators improved. The ingredients are of high quality, and these excellent bacteria support digestion.
8.8
Dramatic improvement
Really good probiotic! Initially, I took one capsule three times a day and felt no difference. After increasing to three capsules three times daily, I experienced a significant improvement in bowel movements. While I still have some symptoms, this probiotic is among the best I’ve tried. I plan to keep using it and recommend it to anyone suffering from IBS or Candidiasis.
8
Supports recovery
It seems to work! I'm using two capsules twice daily as I recover from IBS and Candidiasis overgrowth. I find that it works well.
4
Lactobacillus shows promise for candidiasis
Efficacy and safety of Lactobacillus plantarum P 17630 strain soft vaginal capsule in vaginal candidiasis: a randomized non-inferiority clinical trial.
We assessed how well Lactobacillus plantarum P 17630 works against vaginal candidiasis compared to traditional antifungal treatments like miconazole. In a controlled trial, women with candidiasis took either Lactobacillus capsules or miconazole capsules for several days. Results showed that both treatments reduced vaginitis symptoms over time, with no significant differences. Importantly, Lactobacillus treatment did not lead to any adverse effects and may foster healthier vaginal flora in the long run, potentially decreasing recurring infections.
9
Probiotics enhance candidiasis treatment
Role of Probiotic in Vulvovaginal Candidiasis: A Randomised Controlled Non-blinded Trial from India.
We explored how combining oral probiotics with standard antifungal treatment affects vulvovaginal candidiasis (VVC). In a randomized controlled trial involving 60 patients, we compared results between those receiving antifungal medication alone and those receiving it alongside probiotics.
The results were promising! Participants who took probiotics showed better clinical and mycological outcomes, along with a reduced rate of relapse compared to those on antifungal treatment alone. This suggests that probiotics may be a valuable addition to VVC management.
9
AJCR4 displays antifungal promise
AJCR4: A Potential Probiotic in the Fight Against Oral spp. Biofilms.
We investigated the potential of a newly isolated probiotic, AJCR4, to combat oral candidiasis, a common infection, particularly among immunocompromised individuals. AJCR4 showed strong antifungal effects against both free and biofilm forms of Candida, with impressive results in reducing viable cells in lab tests. In specific biofilms, we observed over 2-log reductions in cell counts. This promising performance suggests that AJCR4 could serve as an effective alternative strategy for treating difficult oral candidiasis cases, especially recurrent infections.
7
Probiotics reduce recurrence rates
The Role of Probiotics in the Treatment of Vulvovaginal Candidiasis: A Systematic Review and Meta-Analysis.
We examined how effective probiotics are for treating vulvovaginal candidiasis, a common vaginal infection. By analyzing six randomized control trials, we compared the effects of probiotics to placebo treatments.
While we found that probiotics did not significantly differ from placebos in the rate of positive cultures, they did show a marked reduction in recurrence rates. This suggests that while they may not eliminate the infection outright, probiotics could help lessen the chance of it coming back, offering a possible alternative treatment.
References
Hu T, Meng Y, Zhao C, Sheng D, Yang S, et al. Genome-scale metabolic modeling reveals specific vaginal strains and their metabolites as key inhibitors of . Microbiol Spectr. 2025. doi:10.1128/spectrum.02984-24
Nachum Z, Suleiman A, Colodner R, Battino S, Wattad M, et al. Oral Probiotics to Prevent Recurrent Vulvovaginal Infections During Pregnancy-Multicenter Double-Blind, Randomized, Placebo-Controlled Trial. Nutrients. 2025;17. doi:10.3390/nu17030460
Rajão A, Silva JPN, Almeida-Nunes DL, Rompante P, Rodrigues CF, et al. AJCR4: A Potential Probiotic in the Fight Against Oral spp. Biofilms. Int J Mol Sci. 2025;26. doi:10.3390/ijms26020638
Horng HC, Xu JW, Kuo YS, Chen YS, Chiu YH, et al. Dual Mechanisms of Action: Anti-Candida and Anti-Inflammatory Potential of Fermentation Broth in Treating Vulvovaginal Candidiasis. J Fungi (Basel). 2024;11. doi:10.3390/jof11010018
Thekho AJ, Mendiratta V, Garg T, Kaur R, Yadav V. Role of Probiotic in Vulvovaginal Candidiasis: A Randomised Controlled Non-blinded Trial from India. Indian J Dermatol. 2024;69:422. doi:10.4103/ijd.ijd_193_24
Bae WY, Lee YJ, Jo S, Shin SL, Kim TR, et al. Effects of LM1215 on and . Yonsei Med J. 2024;65:727. doi:10.3349/ymj.2023.0490
Jang SJ, Jo EJ, Lee C, Cho BR, Shin YJ, et al. Limosilactobacillus fermentum KBL674 Alleviates Vaginal Candidiasis. Probiotics Antimicrob Proteins. 2024. doi:10.1007/s12602-024-10403-3
Ferreira RLPS, Nova BGV, Carmo MS, Abreu AG. Mechanisms of action of Lactobacillus spp. in the treatment of oral candidiasis. Braz J Biol. 2024;84:e282609. doi:10.1590/1519-6984.282609
Vazquez-Munoz R, Thompson A, Sobue T, Dongari-Bagtzoglou A. is a dominant in the murine oral mucosa and has chitinase activity that compromises fungal cell wall integrity. mBio. 2024;15:e0241624. doi:10.1128/mbio.02416-24
Zuñiga Vinueza AM. Probiotics for the Prevention of Vaginal Infections: A Systematic Review. Cureus. 2024;16:e64473. doi:10.7759/cureus.64473
Zhang J, Li K, Cao T, Duan Z. Characterization of a Lactobacillus gasseri strain as a probiotic for female vaginitis. Sci Rep. 2024;14:14426. doi:10.1038/s41598-024-65550-y
Elsayes SA, El Attar MS, ElHadary A, Aboulela AG, Essawy MM, et al. Antimycotic prophylaxis with multispecies probiotics against oral candidiasis in new complete denture wearers: A randomized clinical trial. J Prosthet Dent. 2024. doi:10.1016/j.prosdent.2024.05.018
Zahedifard T, Khadivzadeh T, Rakhshkhorshid M. The Role of Probiotics in the Treatment of Vulvovaginal Candidiasis: A Systematic Review and Meta-Analysis. Ethiop J Health Sci. 2023;33:881. doi:10.4314/ejhs.v33i5.18
Ang XY, Roslan NS, Ahmad N, Yusof SM, Abdullah N, et al. Lactobacillus probiotics restore vaginal and gut microbiota of pregnant women with vaginal candidiasis. Benef Microbes. 2023;14:421. doi:10.1163/18762891-20220103
Bertarello C, Savio D, Morelli L, Bouzalov S, Davidova D, et al. Efficacy and safety of Lactobacillus plantarum P 17630 strain soft vaginal capsule in vaginal candidiasis: a randomized non-inferiority clinical trial. Eur Rev Med Pharmacol Sci. 2024;28:384. doi:10.26355/eurrev_202401_34927
Faustino M, Pereira JO, Pereira AM, Oliveira AS, Ferreira CMH, et al. Vaginal prevention of Candida albicans: synergistic effect of lactobacilli and mannan oligosaccharides (MOS). Appl Microbiol Biotechnol. 2024;108:73. doi:10.1007/s00253-023-12909-2