'
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.8
USERS' SCORE
Good
Based on 14 Reviews
8.7
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B₁₂ (as Methylcobalamin)
1,000 mcg
41,667%

Top Medical Research Studies

8
Vitamin B12 may reduce anxiety
Therapeutic intervention of vitamin B12 in mitigating chronic alcoholism induced alterations in adult zebrafish (): a holistic approach.
Directly addresses anxiety treatment.
We investigated the potential of vitamin B12 to mitigate anxiety in adult zebrafish subjected to chronic alcohol exposure. Our study involved exposing zebrafish to alcohol and then providing them with vitamin B12 to see if it would help reduce anxiety-related behaviors. By using a geotaxis test, we could observe how the fish responded in terms of anxiety in a controlled environment.

The effects were examined alongside oxidative stress and brain health, letting us delve into the biological changes that might occur due to both alcohol and vitamin treatment. The results indicated that chronic alcohol exposure did indeed affect brain function and behavior in the zebrafish. However, we found promising evidence that vitamin B12 operations as a neuroprotective agent, possibly offering relief from the anxiety associated with long-term alcohol use.

Our findings suggest that there may be valuable implications for using vitamin B12 in addressing anxiety related to chronic alcoholism, albeit further studies would be instrumental to fully understand its capabilities and mechanisms.
Read More
8
Vitamin B12 alleviates anxiety symptoms
Effect of vitamin B12 on the symptom severity and psychological profile of fibromyalgia patients; a prospective pre-post study.
Directly addresses anxiety impact
We aimed to understand how vitamin B12 might influence anxiety levels in individuals with fibromyalgia (FM), a condition often characterized by widespread pain and psychological distress.

During our study, we followed FM patients who were given 1000 mcg of vitamin B12 daily for 50 days. To gauge the effects, we compared various measurements taken before and after the treatment, including levels of anxiety and overall health.

The results were promising! We observed significant improvements in anxiety scores among participants after completing the vitamin B12 regimen. This suggests that vitamin B12 could be an effective addition to the treatment plan for those struggling with FM and anxiety.

Given these findings, we believe vitamin B12 holds strong potential as a complementary therapy for FM patients. Enhancing mood and reducing anxiety symptoms could greatly improve their quality of life.
Read More
7
Potential link of vitamin B12 to anxiety
Exploring the Association between Serum B Vitamins, Homocysteine and Mental Disorders: Insights from Mendelian Randomization.
Focus on vitamin B12's effect
We set out to explore the role of serum vitamin B12 levels in relation to anxiety disorders, using a robust methodology that involved genetic data analysis. By pulling information from large-scale genome-wide association studies, we focused on identifying potential causal relationships between vitamin B12 and anxiety symptoms.

Our findings suggest that higher levels of vitamin B12 might be associated with an increased risk of anxiety disorders. Specifically, the analysis revealed that for every unit increase in serum vitamin B12, there's an odds ratio of 1.34 for anxiety disorders. This means that individuals with elevated vitamin B12 levels could be more likely to experience anxiety.

However, it’s essential to note that while there is a suggestive link, the relationship isn't fully straightforward. Other factors could be influencing this association, and we cannot eliminate the possibility that genetic variation might play a role in these findings. Thus, further studies are necessary to validate these results in broader and more diverse populations.

In conclusion, while our study highlights a potential connection between serum vitamin B12 levels and anxiety, it's crucial to approach these observations with caution until more research can provide clearer insights.
Read More

Most Useful Reviews

9.5
Improves anxiety response
With both ADHD and anxiety, I previously relied on meditation and meditation techniques. Upon reading about natural treatments for anxiety, I incorporated Methylcobalamin and Folinic Acid into my routine. The results have been remarkable; I haven't needed Xanax during the day, and my anxiety has significantly decreased. My husband, unaware of the supplements, has also noticed improved handling of daily stresses, which confirms their effectiveness.
Read More
9.5
Significant relief for anxiety
I have dealt with Rheumatoid Arthritis for 45 years and was recently diagnosed with severe anaemia and a B12 deficiency. Following three months of taking 9,000 mcg of Methyl B12 daily, I’ve seen drastic improvements—my neuralgia pain has vanished, and my balance and speech have improved dramatically. Understanding the difference between Methyl B12 and Cyanocobalamin has changed my health for the better.
Read More
8.8
Improved sleep quality
After being a raw foodist and vegan for three years, my B12 levels were critically low at 99 units. I started taking a bioavailable B12 supplement, and after a month, my levels rose to nearly 600 units. I noticed a significant improvement in my sleep and a reduction in my anxiety. I highly recommend this.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.8
8
Vitamin B12 may reduce anxiety
Therapeutic intervention of vitamin B12 in mitigating chronic alcoholism induced alterations in adult zebrafish (): a holistic approach.
Directly addresses anxiety treatment.
We investigated the potential of vitamin B12 to mitigate anxiety in adult zebrafish subjected to chronic alcohol exposure. Our study involved exposing zebrafish to alcohol and then providing them with vitamin B12 to see if it would help reduce anxiety-related behaviors. By using a geotaxis test, we could observe how the fish responded in terms of anxiety in a controlled environment.

The effects were examined alongside oxidative stress and brain health, letting us delve into the biological changes that might occur due to both alcohol and vitamin treatment. The results indicated that chronic alcohol exposure did indeed affect brain function and behavior in the zebrafish. However, we found promising evidence that vitamin B12 operations as a neuroprotective agent, possibly offering relief from the anxiety associated with long-term alcohol use.

Our findings suggest that there may be valuable implications for using vitamin B12 in addressing anxiety related to chronic alcoholism, albeit further studies would be instrumental to fully understand its capabilities and mechanisms.
Read More
8
Vitamin B12 alleviates anxiety symptoms
Effect of vitamin B12 on the symptom severity and psychological profile of fibromyalgia patients; a prospective pre-post study.
Directly addresses anxiety impact
We aimed to understand how vitamin B12 might influence anxiety levels in individuals with fibromyalgia (FM), a condition often characterized by widespread pain and psychological distress.

During our study, we followed FM patients who were given 1000 mcg of vitamin B12 daily for 50 days. To gauge the effects, we compared various measurements taken before and after the treatment, including levels of anxiety and overall health.

The results were promising! We observed significant improvements in anxiety scores among participants after completing the vitamin B12 regimen. This suggests that vitamin B12 could be an effective addition to the treatment plan for those struggling with FM and anxiety.

Given these findings, we believe vitamin B12 holds strong potential as a complementary therapy for FM patients. Enhancing mood and reducing anxiety symptoms could greatly improve their quality of life.
Read More
7
Potential link of vitamin B12 to anxiety
Exploring the Association between Serum B Vitamins, Homocysteine and Mental Disorders: Insights from Mendelian Randomization.
Focus on vitamin B12's effect
We set out to explore the role of serum vitamin B12 levels in relation to anxiety disorders, using a robust methodology that involved genetic data analysis. By pulling information from large-scale genome-wide association studies, we focused on identifying potential causal relationships between vitamin B12 and anxiety symptoms.

Our findings suggest that higher levels of vitamin B12 might be associated with an increased risk of anxiety disorders. Specifically, the analysis revealed that for every unit increase in serum vitamin B12, there's an odds ratio of 1.34 for anxiety disorders. This means that individuals with elevated vitamin B12 levels could be more likely to experience anxiety.

However, it’s essential to note that while there is a suggestive link, the relationship isn't fully straightforward. Other factors could be influencing this association, and we cannot eliminate the possibility that genetic variation might play a role in these findings. Thus, further studies are necessary to validate these results in broader and more diverse populations.

In conclusion, while our study highlights a potential connection between serum vitamin B12 levels and anxiety, it's crucial to approach these observations with caution until more research can provide clearer insights.
Read More
4
Vitamin B12's role in anxiety
Vitamin B12, Folate, Homocysteine, Inflammatory Mediators (Interleukin-6, Tumor Necrosis Factor-α and C-Reactive Protein) Levels in Adolescents with Anxiety or Depressive Symptoms.
Study examines vitamin relationship
We explored the impact of vitamin B12 on anxiety symptoms in adolescents. In a study involving outpatients aged 12 to 18 with anxiety or depressive symptoms, we measured the severity of their conditions and checked various health markers, including serum vitamin B12 and folate levels.

Our findings indicated that lower levels of vitamin B12 were associated with a higher risk of experiencing severe anxiety and depressive symptoms. Interestingly, we also observed that vitamin B12, folate, and total homocysteine levels were interconnected, suggesting that deficiencies in these vitamins might be related.

However, while we found these associations, the correlations between vitamin levels and anxiety symptoms were generally weak.

In summary, while vitamin B12 might play a role in anxiety severity, the relationships are complex and influenced by other factors. Overall, this study underscores the importance of considering nutritional factors in mental health, but we should be cautious not to overstate the benefits of vitamin B12 alone.
Read More

User Reviews

USERS' SCORE
Good
Based on 14 Reviews
8.7
9.5
Anxiety symptom relief
Vitamin B12 (methylcobalamin) offers neuroprotective and immunomodulatory benefits. This chewable form works quickly and significantly alleviated my symptoms of anxiety, breathlessness, and fatigue.
9.5
Fatigue vanquished
After taking this for a month, I experienced massive improvements. The numbness in my arms and legs subsided, and my anxiety completely disappeared.
9.5
Anxiety management success
This is undoubtedly one of the best B12 vitamins available. My levels were critically low, but after supplementing with methylcobalamin, my anxiety is now under control.
9.5
Improves anxiety response
With both ADHD and anxiety, I previously relied on meditation and meditation techniques. Upon reading about natural treatments for anxiety, I incorporated Methylcobalamin and Folinic Acid into my routine. The results have been remarkable; I haven't needed Xanax during the day, and my anxiety has significantly decreased. My husband, unaware of the supplements, has also noticed improved handling of daily stresses, which confirms their effectiveness.
Read More
9.5
Vitamin solution for anxiety
After battling social anxiety disorder my entire life, I discovered that my anxiety stemmed from B-6 and B-12 deficiencies. This revelation came after trying various medications. Thankfully, these inexpensive B vitamins have transformed my life; I now enjoy a more normal existence after years of expenditure on ineffective treatments. It is crucial to select the right type of B-12, avoiding those containing cyanide.
Read More
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