Research Authors

Overview

SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.6
USERS' SCORE
Good
Based on 42 Reviews
8.1
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Phosphatidylserine (PS) from Lecithin (Sunflower) (Helianthus annuus) Seed Oil
100 mg

Top Medical Research Studies

8
Phosphatidylserine improves ADHD symptoms
We examined the effects of soy-derived phosphatidylserine (PS) on attention-deficit hyperactivity disorder (ADHD) in children aged 4-14. In this randomized, double-blind study, 36 children either received 200 mg of PS or a placebo for 2 months.

The results were promising, as PS showed significant improvements in ADHD symptoms and short-term auditory memory. However, not all measurements indicated benefits, and the placebo group didn't show notable changes. Overall, PS appears to be a well-tolerated option for enhancing mental performance in children with ADHD.
Read More
8
Phosphatidylserine shows ADHD potential
We examined how phosphatidylserine enriched with Omega-3 fatty acids might help reduce symptoms of ADHD in children. In a 30-week study, 200 children participated in a double-blind trial followed by an open-label phase.

The results indicated a notable decrease in hyperactive and impulsive behaviors among those receiving the treatment. Children with specific behavioral challenges showed the most improvement.

Overall, phosphatidylserine Omega-3 appears to be a promising option for managing ADHD symptoms, especially in those with higher hyperactivity levels.
Read More
8
Omega-3 PS shows potential for ADHD
We examined how phosphatidylserine, especially when combined with omega-3 fatty acids DHA and EPA, could help reduce symptoms of ADHD. Previous studies have suggested that these compounds can benefit cognitive function, behavior, and mood. In double-blind, randomized trials, we observed promising effects on ADHD symptoms with this combination. However, despite these findings, the overall effectiveness of phosphatidylserine treatment on ADHD remains inconclusive, and further research is needed to firmly establish its benefits.
Read More

Most Useful Reviews

9
Increased motivation
33 people found this helpful
The softgel was more effective than capsules for me. With ADHD and depression, I used to be stressed and unmotivated, but after taking it, I felt a calming effect. It's like a lie how my frustration lessened, and now I feel positive at work. I can't do without it!
Read More
9
Focus enhancement
25 people found this helpful
This supplement helps eliminate past flashbacks and increases my present focus. It also quickens information processing. I come from an ADHD family, so it's surprisingly effective and has markedly improved my quality of life, inspiring me to remain productive during weekends.
Read More
9
Managing ADHD better
14 people found this helpful
I rely on this as a saviour for my ADHD despite the rising cost. I used to struggle with a noisy mind and distractions, but I can't believe how much it alleviates my issues. It's tasteless and easy to take; however, I'm concerned about the price!
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.6
  • All Researches
8
Phosphatidylserine improves ADHD symptoms
We examined the effects of soy-derived phosphatidylserine (PS) on attention-deficit hyperactivity disorder (ADHD) in children aged 4-14. In this randomized, double-blind study, 36 children either received 200 mg of PS or a placebo for 2 months.

The results were promising, as PS showed significant improvements in ADHD symptoms and short-term auditory memory. However, not all measurements indicated benefits, and the placebo group didn't show notable changes. Overall, PS appears to be a well-tolerated option for enhancing mental performance in children with ADHD.
Read More
8
Phosphatidylserine shows ADHD potential
We examined how phosphatidylserine enriched with Omega-3 fatty acids might help reduce symptoms of ADHD in children. In a 30-week study, 200 children participated in a double-blind trial followed by an open-label phase.

The results indicated a notable decrease in hyperactive and impulsive behaviors among those receiving the treatment. Children with specific behavioral challenges showed the most improvement.

Overall, phosphatidylserine Omega-3 appears to be a promising option for managing ADHD symptoms, especially in those with higher hyperactivity levels.
Read More
8
Omega-3 PS shows potential for ADHD
We examined how phosphatidylserine, especially when combined with omega-3 fatty acids DHA and EPA, could help reduce symptoms of ADHD. Previous studies have suggested that these compounds can benefit cognitive function, behavior, and mood. In double-blind, randomized trials, we observed promising effects on ADHD symptoms with this combination. However, despite these findings, the overall effectiveness of phosphatidylserine treatment on ADHD remains inconclusive, and further research is needed to firmly establish its benefits.
Read More
7
Phosphatidylserine shows moderate promise
We evaluated the safety and effectiveness of antioxidant therapies, including phosphatidylserine, for children and adolescents with ADHD. After analyzing data from 48 studies featuring 3,650 participants, we found that while phosphatidylserine showed promise in improving attention and hyperactivity scores, its results were among many factors influenced by other antioxidants. It’s essential to note that the overall quality of the studies was quite low, casting doubt on the findings and suggesting that further high-quality research is needed.
Read More
7
Omega-3 fats show attention benefits
We examined how omega-3 fatty acids, specifically EPA and DHA, affect attention in children with attention challenges. By giving kids aged 8-13 either a placebo, phosphatidylserine (derived from phospholipids), or fish oil for three months, we could track their performance through attention tests.

Our results revealed that those receiving the phosphatidylserine had a greater improvement in their attention scores compared to the other groups. While the omega-3s positively influenced fatty acid levels in the blood, it was mainly the phosphatidylserine that linked to better attention performance.
Read More

User Reviews

USERS' SCORE
Good
Based on 42 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Increased motivation
33 people found this helpful
The softgel was more effective than capsules for me. With ADHD and depression, I used to be stressed and unmotivated, but after taking it, I felt a calming effect. It's like a lie how my frustration lessened, and now I feel positive at work. I can't do without it!
Read More
9
Focus enhancement
25 people found this helpful
This supplement helps eliminate past flashbacks and increases my present focus. It also quickens information processing. I come from an ADHD family, so it's surprisingly effective and has markedly improved my quality of life, inspiring me to remain productive during weekends.
Read More
9
Managing ADHD better
14 people found this helpful
I rely on this as a saviour for my ADHD despite the rising cost. I used to struggle with a noisy mind and distractions, but I can't believe how much it alleviates my issues. It's tasteless and easy to take; however, I'm concerned about the price!
Read More
9
Tantrums eliminated
8 people found this helpful
The nighttime tantrums associated with my child's ADHD are now gone entirely. After a year of taking DHAEPA and vitamin D without any clear effect, we started phosphatidylserine, and by the second week, it had a marked impact. There have been no tantrums at night for a week now, allowing my child to sleep peacefully until morning. This has made childcare significantly easier, although daytime tantrums still persist. I take it once daily after dinner, but I am uncertain if I should increase the dosage to twice a day.
Read More
9
Reduced tantrums
6 people found this helpful
I tried phosphatidylserine for my 5-year-old with ADHD and ASD after reading it was helpful. The effect was immediate; the violent night rampages stopped within a week. Though daytime frustrations persist, they have considerably decreased, confirming its effectiveness for tantrums.
Read More

Frequently Asked Questions

9
Instant clarity
As expected from PS, I feel sharper when taking it. I have ADHD, and it clears my mind almost immediately. The effects are noticeable the following day, and I’m not sleepy during the day. It is somewhat pricey, but the quality is worth it.
9
Tantrums eliminated
8 people found this helpful
The nighttime tantrums associated with my child's ADHD are now gone entirely. After a year of taking DHAEPA and vitamin D without any clear effect, we started phosphatidylserine, and by the second week, it had a marked impact. There have been no tantrums at night for a week now, allowing my child to sleep peacefully until morning. This has made childcare significantly easier, although daytime tantrums still persist. I take it once daily after dinner, but I am uncertain if I should increase the dosage to twice a day.
7.5
Better concentration
11 people found this helpful
My daughter's concentration has notably improved since we began using phosphatidylserine for her ADHD. I opted for this instead of Concerta based on a recommendation. After taking 2 tablets in the morning and 1 in the evening, she can now take notes and focus on her studies without forgetting anything. While the change isn't drastic, it is certainly encouraging, and I plan to continue this regimen.
9
Increased motivation
33 people found this helpful
The softgel was more effective than capsules for me. With ADHD and depression, I used to be stressed and unmotivated, but after taking it, I felt a calming effect. It's like a lie how my frustration lessened, and now I feel positive at work. I can't do without it!
9
Focus enhancement
25 people found this helpful
This supplement helps eliminate past flashbacks and increases my present focus. It also quickens information processing. I come from an ADHD family, so it's surprisingly effective and has markedly improved my quality of life, inspiring me to remain productive during weekends.
9
Fewer mistakes
It worked for my ADHD, leading to fewer careless mistakes, and my mind worked faster! However, it is expensive.
9
Work performance improved
2 people found this helpful
Using this supplement has significantly enhanced my work performance as I manage my ADHD. Combined with Tyrosine, I feel my overall quality of life has improved tremendously, enabling better focus and productivity.
9
Improved discipline
2 people found this helpful
I started this to enhance cognitive functions for managing ADHD, and it works best when paired with Ginkgo. The results have surpassed expectations. It has improved discipline, made habit formation easier, and heightened concentration during tasks. I take one capsule twice a day for a two-month course, and it has been quite effective.
4
Phosphatidylserine shows mixed ADHD effects
We examined the effects of phosphatidylserine on ADHD symptoms in children through a systematic review and meta-analysis.

Our findings highlighted that a dosage of 200-300 mg per day showed a significant improvement in inattention symptoms compared to a placebo.

However, the overall effects on ADHD symptoms and hyperactivity-impulsivity were not statistically significant.

While there's some promise in using phosphatidylserine for inattention, the evidence quality is low, indicating that further research is needed.
8
Phosphatidylserine shows ADHD potential
We examined how phosphatidylserine enriched with Omega-3 fatty acids might help reduce symptoms of ADHD in children. In a 30-week study, 200 children participated in a double-blind trial followed by an open-label phase.

The results indicated a notable decrease in hyperactive and impulsive behaviors among those receiving the treatment. Children with specific behavioral challenges showed the most improvement.

Overall, phosphatidylserine Omega-3 appears to be a promising option for managing ADHD symptoms, especially in those with higher hyperactivity levels.
8
Phosphatidylserine improves ADHD symptoms
We examined the effects of soy-derived phosphatidylserine (PS) on attention-deficit hyperactivity disorder (ADHD) in children aged 4-14. In this randomized, double-blind study, 36 children either received 200 mg of PS or a placebo for 2 months.

The results were promising, as PS showed significant improvements in ADHD symptoms and short-term auditory memory. However, not all measurements indicated benefits, and the placebo group didn't show notable changes. Overall, PS appears to be a well-tolerated option for enhancing mental performance in children with ADHD.
7
Phosphatidylserine shows moderate promise
We evaluated the safety and effectiveness of antioxidant therapies, including phosphatidylserine, for children and adolescents with ADHD. After analyzing data from 48 studies featuring 3,650 participants, we found that while phosphatidylserine showed promise in improving attention and hyperactivity scores, its results were among many factors influenced by other antioxidants. It’s essential to note that the overall quality of the studies was quite low, casting doubt on the findings and suggesting that further high-quality research is needed.
8
Omega-3 PS shows potential for ADHD
We examined how phosphatidylserine, especially when combined with omega-3 fatty acids DHA and EPA, could help reduce symptoms of ADHD. Previous studies have suggested that these compounds can benefit cognitive function, behavior, and mood. In double-blind, randomized trials, we observed promising effects on ADHD symptoms with this combination. However, despite these findings, the overall effectiveness of phosphatidylserine treatment on ADHD remains inconclusive, and further research is needed to firmly establish its benefits.

References

  1. Zhou P, Yu X, Song T, Hou X. Safety and efficacy of antioxidant therapy in children and adolescents with attention deficit hyperactivity disorder: A systematic review and network meta-analysis. PLoS One. 2024;19:e0296926. 10.1371/journal.pone.0296926
  2. Bruton A, Nauman J, Hanes D, Gard M, Senders A. Phosphatidylserine for the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis. J Altern Complement Med. 2021;27:312. 10.1089/acm.2020.0432
  3. Hirayama S, Terasawa K, Rabeler R, Hirayama T, Inoue T, et al. The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial. J Hum Nutr Diet. 2014;27 Suppl 2:284. 10.1111/jhn.12090
  4. Manor I, Magen A, Keidar D, Rosen S, Tasker H, et al. Safety of phosphatidylserine containing omega3 fatty acids in ADHD children: a double-blind placebo-controlled trial followed by an open-label extension. Eur Psychiatry. 2013;28:386. 10.1016/j.eurpsy.2012.11.001
  5. Manor I, Magen A, Keidar D, Rosen S, Tasker H, et al. The effect of phosphatidylserine containing Omega3 fatty-acids on attention-deficit hyperactivity disorder symptoms in children: a double-blind placebo-controlled trial, followed by an open-label extension. Eur Psychiatry. 2012;27:335. 10.1016/j.eurpsy.2011.05.004
  6. Vaisman N, Kaysar N, Zaruk-Adasha Y, Pelled D, Brichon G, et al. Correlation between changes in blood fatty acid composition and visual sustained attention performance in children with inattention: effect of dietary n-3 fatty acids containing phospholipids. Am J Clin Nutr. 2008;87:1170.
  7. Kidd PM. Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings and structural-functional synergies with cell membrane phospholipids. Altern Med Rev. 2007;12:207.
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