Phosphatidylserine (PS) from Lecithin (Sunflower) (Helianthus annuus) Seed Oil
100 mg
†
Top Medical Research Studies
8
Phosphatidylserine improves ADHD symptoms
The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial.
We examined the effects of soy-derived phosphatidylserine (PS) on attention-deficit hyperactivity disorder (ADHD) in children aged 4-14. In this randomized, double-blind study, 36 children either received 200 mg of PS or a placebo for 2 months.
The results were promising, as PS showed significant improvements in ADHD symptoms and short-term auditory memory. However, not all measurements indicated benefits, and the placebo group didn't show notable changes. Overall, PS appears to be a well-tolerated option for enhancing mental performance in children with ADHD.
Read More
8
Phosphatidylserine shows ADHD potential
The effect of phosphatidylserine containing Omega3 fatty-acids on attention-deficit hyperactivity disorder symptoms in children: a double-blind placebo-controlled trial, followed by an open-label extension.
We examined how phosphatidylserine enriched with Omega-3 fatty acids might help reduce symptoms of ADHD in children. In a 30-week study, 200 children participated in a double-blind trial followed by an open-label phase.
The results indicated a notable decrease in hyperactive and impulsive behaviors among those receiving the treatment. Children with specific behavioral challenges showed the most improvement.
Overall, phosphatidylserine Omega-3 appears to be a promising option for managing ADHD symptoms, especially in those with higher hyperactivity levels.
Read More
8
Omega-3 PS shows potential for ADHD
Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings and structural-functional synergies with cell membrane phospholipids.
We examined how phosphatidylserine, especially when combined with omega-3 fatty acids DHA and EPA, could help reduce symptoms of ADHD. Previous studies have suggested that these compounds can benefit cognitive function, behavior, and mood. In double-blind, randomized trials, we observed promising effects on ADHD symptoms with this combination. However, despite these findings, the overall effectiveness of phosphatidylserine treatment on ADHD remains inconclusive, and further research is needed to firmly establish its benefits.
Read More
Most Useful Reviews
9
Increased motivation
33 people found this helpful
The softgel was more effective than capsules for me. With ADHD and depression, I used to be stressed and unmotivated, but after taking it, I felt a calming effect. It's like a lie how my frustration lessened, and now I feel positive at work. I can't do without it!
Read More
9
Focus enhancement
25 people found this helpful
This supplement helps eliminate past flashbacks and increases my present focus. It also quickens information processing. I come from an ADHD family, so it's surprisingly effective and has markedly improved my quality of life, inspiring me to remain productive during weekends.
Read More
9
Managing ADHD better
14 people found this helpful
I rely on this as a saviour for my ADHD despite the rising cost. I used to struggle with a noisy mind and distractions, but I can't believe how much it alleviates my issues. It's tasteless and easy to take; however, I'm concerned about the price!
The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial.
We examined the effects of soy-derived phosphatidylserine (PS) on attention-deficit hyperactivity disorder (ADHD) in children aged 4-14. In this randomized, double-blind study, 36 children either received 200 mg of PS or a placebo for 2 months.
The results were promising, as PS showed significant improvements in ADHD symptoms and short-term auditory memory. However, not all measurements indicated benefits, and the placebo group didn't show notable changes. Overall, PS appears to be a well-tolerated option for enhancing mental performance in children with ADHD.
Read More
8
Phosphatidylserine shows ADHD potential
The effect of phosphatidylserine containing Omega3 fatty-acids on attention-deficit hyperactivity disorder symptoms in children: a double-blind placebo-controlled trial, followed by an open-label extension.
We examined how phosphatidylserine enriched with Omega-3 fatty acids might help reduce symptoms of ADHD in children. In a 30-week study, 200 children participated in a double-blind trial followed by an open-label phase.
The results indicated a notable decrease in hyperactive and impulsive behaviors among those receiving the treatment. Children with specific behavioral challenges showed the most improvement.
Overall, phosphatidylserine Omega-3 appears to be a promising option for managing ADHD symptoms, especially in those with higher hyperactivity levels.
Read More
8
Omega-3 PS shows potential for ADHD
Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings and structural-functional synergies with cell membrane phospholipids.
We examined how phosphatidylserine, especially when combined with omega-3 fatty acids DHA and EPA, could help reduce symptoms of ADHD. Previous studies have suggested that these compounds can benefit cognitive function, behavior, and mood. In double-blind, randomized trials, we observed promising effects on ADHD symptoms with this combination. However, despite these findings, the overall effectiveness of phosphatidylserine treatment on ADHD remains inconclusive, and further research is needed to firmly establish its benefits.
Read More
7
Phosphatidylserine shows moderate promise
Safety and efficacy of antioxidant therapy in children and adolescents with attention deficit hyperactivity disorder: A systematic review and network meta-analysis.
We evaluated the safety and effectiveness of antioxidant therapies, including phosphatidylserine, for children and adolescents with ADHD. After analyzing data from 48 studies featuring 3,650 participants, we found that while phosphatidylserine showed promise in improving attention and hyperactivity scores, its results were among many factors influenced by other antioxidants. It’s essential to note that the overall quality of the studies was quite low, casting doubt on the findings and suggesting that further high-quality research is needed.
Read More
7
Omega-3 fats show attention benefits
Correlation between changes in blood fatty acid composition and visual sustained attention performance in children with inattention: effect of dietary n-3 fatty acids containing phospholipids.
We examined how omega-3 fatty acids, specifically EPA and DHA, affect attention in children with attention challenges. By giving kids aged 8-13 either a placebo, phosphatidylserine (derived from phospholipids), or fish oil for three months, we could track their performance through attention tests.
Our results revealed that those receiving the phosphatidylserine had a greater improvement in their attention scores compared to the other groups. While the omega-3s positively influenced fatty acid levels in the blood, it was mainly the phosphatidylserine that linked to better attention performance.
The softgel was more effective than capsules for me. With ADHD and depression, I used to be stressed and unmotivated, but after taking it, I felt a calming effect. It's like a lie how my frustration lessened, and now I feel positive at work. I can't do without it!
Read More
9
Focus enhancement
25 people found this helpful
This supplement helps eliminate past flashbacks and increases my present focus. It also quickens information processing. I come from an ADHD family, so it's surprisingly effective and has markedly improved my quality of life, inspiring me to remain productive during weekends.
Read More
9
Managing ADHD better
14 people found this helpful
I rely on this as a saviour for my ADHD despite the rising cost. I used to struggle with a noisy mind and distractions, but I can't believe how much it alleviates my issues. It's tasteless and easy to take; however, I'm concerned about the price!
Read More
9
Tantrums eliminated
8 people found this helpful
The nighttime tantrums associated with my child's ADHD are now gone entirely. After a year of taking DHAEPA and vitamin D without any clear effect, we started phosphatidylserine, and by the second week, it had a marked impact. There have been no tantrums at night for a week now, allowing my child to sleep peacefully until morning. This has made childcare significantly easier, although daytime tantrums still persist. I take it once daily after dinner, but I am uncertain if I should increase the dosage to twice a day.
Read More
9
Reduced tantrums
6 people found this helpful
I tried phosphatidylserine for my 5-year-old with ADHD and ASD after reading it was helpful. The effect was immediate; the violent night rampages stopped within a week. Though daytime frustrations persist, they have considerably decreased, confirming its effectiveness for tantrums.
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental condition characterized by a persistent pattern of inattention and/or hyperactivity-impulsivity that interferes with functioning or development. The symptoms typically present in early childhood and can continue into adolescence and adulthood. Individuals with ADHD may find it challenging to focus, organize tasks, follow through on instructions, and regulate their emotions. Hyperactivity can manifest as excessive fidgeting or an inability to remain seated in structured environments, while impulsivity may lead to hasty actions without considering the consequences.
Diagnosis of ADHD involves comprehensive assessments, often including behavioral evaluations and standardized rating scales, to determine how symptoms impact the individual’s daily life. Treatment can vary widely and may include behavioral therapy, psychoeducation, and medications such as stimulants or non-stimulants, aimed at improving attention span and impulse control. Understanding ADHD is crucial, not only for effective management but also for reducing stigma and promoting awareness. As our understanding of neurodiversity expands, more resources and support systems are becoming available to help those with ADHD thrive in both academic and social settings.
Phosphatidylserine is a phospholipid that is a vital component of cell membranes, particularly within the brain. It plays a crucial role in cellular function, including cell signaling, apoptosis (programmed cell death), and maintaining the structure of neuronal membranes. As a dietary supplement, phosphatidylserine is often marketed for its potential cognitive benefits, including improving memory, attention, and overall mental clarity, particularly in aging populations. While some studies have suggested that it may help reduce symptoms of cognitive decline and stress, more research is needed to fully understand its effectiveness and the mechanisms behind its action.
Phosphatidylserine can be obtained from dietary sources, such as soybeans, white beans, and egg yolks, though supplementation is common for those looking for higher doses. When considering a phosphatidylserine supplement, it's important to look for high-quality, reputable brands and consult with a healthcare professional, especially if you’re pregnant, nursing, or taking other medications. The safety profile of phosphatidylserine is generally good, although some may experience gastrointestinal discomfort as a side effect.
Phosphatidylserine is a phospholipid that plays a crucial role in maintaining cellular function, especially in the brain. Some studies suggest that phosphatidylserine may have a positive impact on attention and cognitive function, which is particularly relevant for individuals with ADHD. The mechanism is thought to involve enhancing communication between neurons and reducing stress-related hormones, which can contribute to improved focus and reduced impulsivity.
However, while there is some preliminary evidence pointing towards its potential benefits for ADHD symptoms, further research is needed to establish its efficacy definitively. It's essential to consult with a healthcare provider before starting any supplement, including phosphatidylserine, especially for managing conditions like ADHD. They can provide personalized advice and ensure that it fits within a broader treatment plan.
Based on user reviews, the time it takes to see results from this supplement for ADHD can vary. Some users reported immediate effects, noting significant improvements in focus and cognitive clarity within the first week of use. For instance, one reviewer indicated that their child's violent night rampages stopped within a week of starting phosphatidylserine Read Review. Similarly, another user claimed sharp mental clarity was noticeable almost immediately with the effects reported the following day Read Review.
On the other hand, some users took a couple of weeks before noticing significant changes, with one observation highlighting marked improvements in just the second week Read Review. Additionally, a user noted that while the impact on concentration after beginning use wasn't drastic, it was encouraging enough to continue the regimen Read Review. Thus, while some see quick results, others may need to remain patient for a few weeks to assess the full benefits of the supplement.
Phosphatidylserine has shown some potential in improving symptoms of ADHD, particularly in areas of inattention and hyperactivity, based on several studies. One systematic review found that a dosage of 200-300 mg per day resulted in significant improvements in inattention symptoms among children with ADHD, although the overall effects on hyperactivity and impulsivity were not statistically significant. Notably, the quality of the evidence is considered low, indicating a need for more robust research in this area [2].
Various studies, including those combining phosphatidylserine with omega-3 fatty acids, have also suggested benefits for managing ADHD symptoms, especially in children displaying higher levels of hyperactivity. While some results indicated improvements in attention and behavioral measures, these studies collectively highlighted the limitations of their findings due to low-quality data and inconsistent results. Overall, phosphatidylserine appears to be a well-tolerated option, but conclusive evidence regarding its effectiveness in treating ADHD symptoms remains elusive, warranting further exploration and high-quality trials [1][5].
Based on user reviews, many individuals report a range of significant improvements in their symptoms associated with ADHD after incorporating this supplement into their routine. For instance, one user mentioned that they felt a notable calming effect, leading to a decrease in frustration and an overall positive mood at work Read Review. Other users have noted enhancements in focus and information processing, claiming that the supplement helped them stay productive throughout their weekends Read Review.
Moreover, parents reported that their children's nighttime tantrums associated with ADHD diminished entirely after just a couple of weeks of use, which considerably eased nighttime routines Read Review. Some users found that their concentration improved, allowing them to complete tasks without procrastination, while others remarked on a clearer mind and reduced careless mistakes Read Review. Overall, while responses can vary from person to person, many users express satisfaction with the positive effects on focus, clarity, and emotional stability attributed to the supplement.
Based on user reviews, there is a notable interest in combining this supplement with other products to enhance its effectiveness for managing ADHD symptoms. For instance, one user reported that pairing it with Tyrosine led to significant improvements in focus and overall quality of life Read Review. Another user found that combining it with Ginkgo exceeded their expectations, particularly in improving discipline and habit formation Read Review. These combinations suggest that some users are actively exploring synergistic effects to optimize their ADHD management strategies.
Additionally, parents of children with ADHD have reported success in reducing tantrums and improving emotional stability by introducing this supplement alongside other routines Read Review. While many have found it effective on its own, these reviews indicate that there is potential for enhanced results when used in conjunction with other supplements or strategies. As always, it’s advisable for individuals considering combinations to consult healthcare professionals to ensure personalized and safe approaches to managing ADHD.
The optimal dosage of phosphatidylserine for managing ADHD symptoms in children appears to fall within the range of 200 to 300 mg per day. Research has shown that this dosage can lead to significant improvements in inattention symptoms compared to a placebo, indicating a potential benefit in addressing ADHD challenges [2]. Notably, in a randomized study involving children ages 4 to 14, a 200 mg dose of soy-derived phosphatidylserine displayed promising results in alleviating ADHD symptoms and enhancing short-term memory, although the benefits were not universally observed across all measured outcomes [3].
While phosphatidylserine may offer some hope for improving ADHD symptoms, it’s crucial to acknowledge that the overall quality of the evidence is low, and many studies suggest that further high-quality research is necessary to confirm these findings [1]. Consequently, while 200-300 mg daily is considered optimal based on current available research, parents and caregivers should consult healthcare professionals before starting any new supplementation for ADHD [7].
9
Instant clarity
As expected from PS, I feel sharper when taking it. I have ADHD, and it clears my mind almost immediately. The effects are noticeable the following day, and I’m not sleepy during the day. It is somewhat pricey, but the quality is worth it.
9
Tantrums eliminated
8 people found this helpful
The nighttime tantrums associated with my child's ADHD are now gone entirely. After a year of taking DHAEPA and vitamin D without any clear effect, we started phosphatidylserine, and by the second week, it had a marked impact. There have been no tantrums at night for a week now, allowing my child to sleep peacefully until morning. This has made childcare significantly easier, although daytime tantrums still persist. I take it once daily after dinner, but I am uncertain if I should increase the dosage to twice a day.
7.5
Better concentration
11 people found this helpful
My daughter's concentration has notably improved since we began using phosphatidylserine for her ADHD. I opted for this instead of Concerta based on a recommendation. After taking 2 tablets in the morning and 1 in the evening, she can now take notes and focus on her studies without forgetting anything. While the change isn't drastic, it is certainly encouraging, and I plan to continue this regimen.
9
Increased motivation
33 people found this helpful
The softgel was more effective than capsules for me. With ADHD and depression, I used to be stressed and unmotivated, but after taking it, I felt a calming effect. It's like a lie how my frustration lessened, and now I feel positive at work. I can't do without it!
9
Focus enhancement
25 people found this helpful
This supplement helps eliminate past flashbacks and increases my present focus. It also quickens information processing. I come from an ADHD family, so it's surprisingly effective and has markedly improved my quality of life, inspiring me to remain productive during weekends.
9
Fewer mistakes
It worked for my ADHD, leading to fewer careless mistakes, and my mind worked faster! However, it is expensive.
9
Work performance improved
2 people found this helpful
Using this supplement has significantly enhanced my work performance as I manage my ADHD. Combined with Tyrosine, I feel my overall quality of life has improved tremendously, enabling better focus and productivity.
9
Improved discipline
2 people found this helpful
I started this to enhance cognitive functions for managing ADHD, and it works best when paired with Ginkgo. The results have surpassed expectations. It has improved discipline, made habit formation easier, and heightened concentration during tasks. I take one capsule twice a day for a two-month course, and it has been quite effective.
4
Phosphatidylserine shows mixed ADHD effects
Phosphatidylserine for the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis.
We examined the effects of phosphatidylserine on ADHD symptoms in children through a systematic review and meta-analysis.
Our findings highlighted that a dosage of 200-300 mg per day showed a significant improvement in inattention symptoms compared to a placebo.
However, the overall effects on ADHD symptoms and hyperactivity-impulsivity were not statistically significant.
While there's some promise in using phosphatidylserine for inattention, the evidence quality is low, indicating that further research is needed.
8
Phosphatidylserine shows ADHD potential
The effect of phosphatidylserine containing Omega3 fatty-acids on attention-deficit hyperactivity disorder symptoms in children: a double-blind placebo-controlled trial, followed by an open-label extension.
We examined how phosphatidylserine enriched with Omega-3 fatty acids might help reduce symptoms of ADHD in children. In a 30-week study, 200 children participated in a double-blind trial followed by an open-label phase.
The results indicated a notable decrease in hyperactive and impulsive behaviors among those receiving the treatment. Children with specific behavioral challenges showed the most improvement.
Overall, phosphatidylserine Omega-3 appears to be a promising option for managing ADHD symptoms, especially in those with higher hyperactivity levels.
8
Phosphatidylserine improves ADHD symptoms
The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial.
We examined the effects of soy-derived phosphatidylserine (PS) on attention-deficit hyperactivity disorder (ADHD) in children aged 4-14. In this randomized, double-blind study, 36 children either received 200 mg of PS or a placebo for 2 months.
The results were promising, as PS showed significant improvements in ADHD symptoms and short-term auditory memory. However, not all measurements indicated benefits, and the placebo group didn't show notable changes. Overall, PS appears to be a well-tolerated option for enhancing mental performance in children with ADHD.
7
Phosphatidylserine shows moderate promise
Safety and efficacy of antioxidant therapy in children and adolescents with attention deficit hyperactivity disorder: A systematic review and network meta-analysis.
We evaluated the safety and effectiveness of antioxidant therapies, including phosphatidylserine, for children and adolescents with ADHD. After analyzing data from 48 studies featuring 3,650 participants, we found that while phosphatidylserine showed promise in improving attention and hyperactivity scores, its results were among many factors influenced by other antioxidants. It’s essential to note that the overall quality of the studies was quite low, casting doubt on the findings and suggesting that further high-quality research is needed.
8
Omega-3 PS shows potential for ADHD
Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings and structural-functional synergies with cell membrane phospholipids.
We examined how phosphatidylserine, especially when combined with omega-3 fatty acids DHA and EPA, could help reduce symptoms of ADHD. Previous studies have suggested that these compounds can benefit cognitive function, behavior, and mood. In double-blind, randomized trials, we observed promising effects on ADHD symptoms with this combination. However, despite these findings, the overall effectiveness of phosphatidylserine treatment on ADHD remains inconclusive, and further research is needed to firmly establish its benefits.
References
Zhou P, Yu X, Song T, Hou X. Safety and efficacy of antioxidant therapy in children and adolescents with attention deficit hyperactivity disorder: A systematic review and network meta-analysis. PLoS One. 2024;19:e0296926. 10.1371/journal.pone.0296926
Bruton A, Nauman J, Hanes D, Gard M, Senders A. Phosphatidylserine for the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis. J Altern Complement Med. 2021;27:312. 10.1089/acm.2020.0432
Hirayama S, Terasawa K, Rabeler R, Hirayama T, Inoue T, et al. The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial. J Hum Nutr Diet. 2014;27 Suppl 2:284. 10.1111/jhn.12090
Manor I, Magen A, Keidar D, Rosen S, Tasker H, et al. Safety of phosphatidylserine containing omega3 fatty acids in ADHD children: a double-blind placebo-controlled trial followed by an open-label extension. Eur Psychiatry. 2013;28:386. 10.1016/j.eurpsy.2012.11.001
Manor I, Magen A, Keidar D, Rosen S, Tasker H, et al. The effect of phosphatidylserine containing Omega3 fatty-acids on attention-deficit hyperactivity disorder symptoms in children: a double-blind placebo-controlled trial, followed by an open-label extension. Eur Psychiatry. 2012;27:335. 10.1016/j.eurpsy.2011.05.004
Vaisman N, Kaysar N, Zaruk-Adasha Y, Pelled D, Brichon G, et al. Correlation between changes in blood fatty acid composition and visual sustained attention performance in children with inattention: effect of dietary n-3 fatty acids containing phospholipids. Am J Clin Nutr. 2008;87:1170.
Kidd PM. Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings and structural-functional synergies with cell membrane phospholipids. Altern Med Rev. 2007;12:207.