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Results showed that while EpiCor did modify the gut microbiome, any improvements in constipation symptoms were modest. Interestingly, the treatment seemed to encourage a quicker transit time for digestion, possibly changing the balance of gut bacteria. Overall, EpiCor may have some benefits, but its effects were not as significant as anticipated.
The results were promising: probiotics reduced the incidence of AAD from 19% to 8%. While results were generally optimistic, with no serious side effects reported, moderate evidence suggests further studies are needed before fully endorsing probiotics for all pediatric patients.
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The results were promising: probiotics reduced the incidence of AAD from 19% to 8%. While results were generally optimistic, with no serious side effects reported, moderate evidence suggests further studies are needed before fully endorsing probiotics for all pediatric patients.
Results showed pain scores decreased dramatically, and all quality of life measures improved after treatment. This suggests that Saccharomyces cerevisiae could be an effective option for those looking to alleviate IBS symptoms.
After monitoring their bowel movements, colonic transit time (CTT), and bloating, we found that TRANSITECH significantly increased their bowel movements and improved transit times without causing discomfort.
Impressively, these benefits continued even after participants stopped using the supplement.
Most reported a reduction in stool frequency and alleviation of discomfort, such as flatulence and abdominal pain. In fact, 92.9% of the 141 patients in the main treatment group experienced a noticeable improvement after the treatment course.
Overall, the findings suggest that Saccharomyces boulardii can effectively enhance intestinal health in individuals affected by gastrointestinal disorders, including constipation.
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Frequently Asked Questions
Constipation is a common condition characterized by infrequent bowel movements or difficulty passing stools. It is typically defined as having fewer than three bowel movements per week, leading to hard, dry stools that are painful or difficult to expel. This condition can be caused by a variety of factors, including diet, dehydration, lack of physical activity, and certain medications. Stress and lifestyle changes can also contribute, making it essential for individuals to identify the root causes of their constipation for effective relief.
To alleviate constipation, it’s recommended to increase fiber intake by consuming more fruits, vegetables, whole grains, and legumes, as well as ensuring adequate hydration throughout the day. Regular exercise can also promote healthy bowel function. If over-the-counter solutions such as fiber supplements or laxatives aren't effective, it's advisable to consult a healthcare provider, as chronic constipation can lead to complications and indicate underlying health issues. Keeping a consistent eating and bathroom schedule can also help regulate bowel movements.
Saccharomyces boulardii is a beneficial yeast strain known for its probiotic properties. Originally isolated from lychee and mangosteen fruit in the 1920s by French microbiologist Henri Boulard, this yeast is widely recognized for its ability to support digestive health. It is commonly used to prevent and treat diarrhea, especially in cases related to antibiotic use or gastrointestinal infections. Saccharomyces boulardii works by helping to maintain the natural balance of good bacteria in the gut, promoting the growth of beneficial microorganisms, and producing substances that inhibit pathogen growth.
In addition to its anti-diarrheal benefits, research suggests that Saccharomyces boulardii may also contribute to other health benefits, including digestive recovery after gastrointestinal illness and potential support for conditions like irritable bowel syndrome (IBS). While it is generally regarded as safe for most individuals, those with compromised immune systems or central venous catheters should consult healthcare professionals prior to use. As always, it's best to choose high-quality supplements that clearly specify the strain and dosage of Saccharomyces boulardii to ensure efficacy.
Saccharomyces boulardii is a probiotic yeast that has gained recognition for its role in supporting digestive health. While it is primarily known for its efficacy in treating diarrhea, some evidence suggests that it may also have a soothing effect on constipation. Probiotics like Saccharomyces boulardii can help balance gut flora, which might contribute to improved bowel regularity. However, research specifically linking this probiotic to alleviation of constipation is limited.
If you're considering using Saccharomyces boulardii for constipation, it’s essential to consult with a healthcare professional first. Their guidance can help ensure it’s appropriate for your situation and prevent any potential interactions with other treatments you may be using. Overall, while it shows promise for various digestive issues, individual responses to probiotics can vary, and more research is needed to fully understand its effects on constipation.
When it comes to seeing results from this supplement for constipation, user reviews suggest a varied timeline. Some users report experiencing effective relief within a week of starting the supplement. For instance, one reviewer noted, "It alleviates constipation and excessive gas formation...after a week" (Read Review). Others, however, had a more protracted experience, with some stating that significant improvements came after several weeks or months of consistent use. One user shared their positive experience after three months of therapy, saying, "I’m feeling much better" (Read Review).
On the flip side, some users faced challenges. Several noted that, while the product worked well for many, they experienced constipation or other digestive issues that made their initial experience less than ideal. For example, one reviewer mentioned that they experienced constipation after taking the product for six months (Read Review). Therefore, while immediate benefits may occur for some, it's important to remember that each individual's experience can differ greatly.
The preliminary research suggests that supplements, particularly those containing Saccharomyces boulardii, may offer some support in managing constipation. For instance, a study involving 209 patients found significant improvements in gastrointestinal health for those taking Saccharomyces boulardii, although the results indicate it's not the primary recommended treatment for constipation due to mixed effectiveness compared to other therapies [4]. Another study noted that this probiotic reduced the incidence of constipation in patients undergoing Helicobacter pylori treatment, which suggests that while it may not be a standalone solution, it can mitigate constipation as a side effect of other treatments [6].
However, additional studies emphasize that while Saccharomyces boulardii can provide certain benefits, such as influencing bowel movement patterns and intestinal flora, the evidence is not overwhelmingly conclusive for it being a primary remedy for constipation. For instance, in children, a trial showed that saccharomyces boulardii's effectiveness did not surpass that of lactulose, and it had a higher rate of necessary medication changes [3]. Overall, while there's promise in specific contexts, more targeted research is necessary to fully establish the efficacy of this supplement for constipation relief.
Based on user reviews, many individuals have reported significant improvements in their digestive symptoms with this probiotic supplement. Users frequently mention relief from constipation, with one reporting that their constipation and excessive gas were alleviated, noting "excellent health improvements after a week" of daily use (Read Review). Another reviewer highlighted its effectiveness in managing chronic constipation, stating it provided "immediate relief" while also supporting overall digestive health (Read Review). Additionally, a user mentioned that they had struggled with severe diarrhoea and have since found their stools to be consistently regular since starting the supplement (Read Review).
Conversely, it's essential to note that individual experiences can vary widely. Some users reported adverse effects such as constipation and bloating, suggesting that the product may not suit everyone (Read Review). For example, one user experienced persistent constipation after six months of use, highlighting that while the product was helpful for some, it could lead to issues for others (Read Review). Therefore, while many have found relief and improvement in their digestive symptoms, it is critical for potential users to consider their unique digestive health when deciding to try this supplement.
Based on user reviews, many individuals have reported a positive experience when combining this supplement with other digestive health practices for managing constipation. Users noted enhanced relief from constipation, with one stating that the product effectively eliminated the issue and helped with bloating as well (Read Review). Several reviews also indicate that the supplement has worked favorably for conditions like diarrhoea and gastrointestinal discomfort, showcasing its versatility. For instance, one user found it beneficial not only for their own digestion but also for their children during episodes of diarrhoea, reporting superior effects compared to other treatments (Read Review).
However, not all users experienced the same results, as some reported adverse effects when combining the supplement with other treatments or dietary adjustments. Individuals with specific conditions, like bacterial overgrowth or SIBO, noted exacerbated symptoms including constipation and bloating due to the supplement (Read Review) (Read Review). Therefore, while many found success, others encountered challenges, highlighting the importance of tailoring supplement use to individual health needs and conditions.
Based on user reviews, the consensus on the appropriate dose of Saccharomyces Boulardii for treating constipation varies, but many users found success with a regimen of one capsule daily. For instance, one reviewer stated that after taking one capsule a day, they noticed significant health improvements within a week, alleviating both constipation and excessive gas ((Read Review)). Others echoed similar sentiments, with reports of the probiotic effectively managing constipation symptoms when taken consistently over time ((Read Review)).
However, it is essential to note that not all experiences were positive, as some users reported instances of increased constipation after prolonged use, indicating that individual responses can vary significantly. For example, one user mentioned experiencing constipation after taking the product for six months, leading to disappointment with their purchase ((Read Review)). Another individual noted that this probiotic could exacerbate existing conditions like bacterial overgrowth syndrome, leading to severe constipation ((Read Review)). Ultimately, while many found Saccharomyces Boulardii beneficial for managing constipation, it appears that dosing and personal health conditions play a crucial role in individual results.
Most reported a reduction in stool frequency and alleviation of discomfort, such as flatulence and abdominal pain. In fact, 92.9% of the 141 patients in the main treatment group experienced a noticeable improvement after the treatment course.
Overall, the findings suggest that Saccharomyces boulardii can effectively enhance intestinal health in individuals affected by gastrointestinal disorders, including constipation.
Our analysis included 18 trials with over 3,500 patients. The results showed that S. boulardii not only helped boost H. pylori eradication rates but also reduced the incidence of constipation.
Overall, S. boulardii appears beneficial as it increases treatment success while decreasing side effects, making it a promising option for those undergoing H. pylori therapy.
By week 12, the success rates for bowel movements were significantly higher in the lactulose and combination groups compared to the monotherapy group. However, we found that Saccharomyces boulardii's effectiveness did not exceed that of lactulose alone, as it had a higher rate of required medication changes.
Overall, the findings suggest that probiotics like Saccharomyces boulardii may not be the primary recommended treatment for this condition.
References
- Tang S, Li J, Li Y, Du H, Zhu W, et al. Effects of Saccharomyces boulardii on microbiota composition and metabolite levels in the small intestine of constipated mice. BMC Microbiol. 2024;24:493. doi:10.1186/s12866-024-03647-0
- Chen Y, Teng T, Su Y, Chen WZ. The effect of supplementing with on bismuth quadruple therapy for eradicating : a systematic review and meta-analysis of randomized controlled trials. Front Med (Lausanne). 2024;11:1344702. doi:10.3389/fmed.2024.1344702
- Lee KJ, Ryoo E, Lee YM, Yoon JM, Jang HJ, et al. and Lactulose for Childhood Functional Constipation: A Multicenter Randomized Controlled Trial. J Neurogastroenterol Motil. 2022;28:454. doi:10.5056/jnm21130
- Kvit AD, Tutka MM, Laba OV, Kunovskiy VV. APPLICATION OF THE SACCHAROMYCES BOULARDII PROBIOTIC COMPLEX IN THE CORRECTION OF INTRAINTESTINAL HOMEOSTASIS IN PATIENTS WITH DYSBIOTIC DISORDERS DUE TO ANTIBIOTIC THERAPY. Wiad Lek. 2021;74:1655.
- García-Collinot G, Madrigal-Santillán EO, Martínez-Bencomo MA, Carranza-Muleiro RA, Jara LJ, et al. Effectiveness of Saccharomyces boulardii and Metronidazole for Small Intestinal Bacterial Overgrowth in Systemic Sclerosis. Dig Dis Sci. 2020;65:1134. doi:10.1007/s10620-019-05830-0
- Zhou BG, Chen LX, Li B, Wan LY, Ai YW. Saccharomyces boulardii as an adjuvant therapy for Helicobacter pylori eradication: A systematic review and meta-analysis with trial sequential analysis. Helicobacter. 2019;24:e12651. doi:10.1111/hel.12651
- Leventogiannis K, Gkolfakis P, Spithakis G, Tsatali A, Pistiki A, et al. Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial Overgrowth. Probiotics Antimicrob Proteins. 2019;11:627. doi:10.1007/s12602-018-9401-3
- Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, et al. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev. 2015. doi:10.1002/14651858.CD004827.pub4
- Zhao HM, Ou-Yang HJ, Duan BP, Xu B, Chen ZY, et al. [Clinical effect of triple therapy combined with Saccharomyces boulardii in the treatment of Helicobacter pylori infection in children]. Zhongguo Dang Dai Er Ke Za Zhi. 2014;16:230.
- Siyal M, Abbas Z, Amir MR, Qadeer MA. Saccharomyces cerevisiae for abdominal pain and discomfort in irritable bowel syndrome patients. Pak J Med Sci. 2024;40:492. doi:10.12669/pjms.40.3.8349
- Mourey F, Decherf A, Jeanne JF, Clément-Ziza M, Grisoni ML, et al. I-3856 in irritable bowel syndrome with predominant constipation. World J Gastroenterol. 2022;28:2509. doi:10.3748/wjg.v28.i22.2509
- Chen Z, Lin S, Jiang Y, Liu L, Jiang J, et al. Effects of Bread Yeast Cell Wall Beta-Glucans on Mice with Loperamide-Induced Constipation. J Med Food. 2019;22:1009. doi:10.1089/jmf.2019.4407
- Lim JM, Kim YD, Song CH, Park SJ, Park DC, et al. Laxative effects of triple fermented barley extracts (FBe) on loperamide (LP)-induced constipation in rats. BMC Complement Altern Med. 2019;19:143. doi:10.1186/s12906-019-2557-x
- Pinheiro I, Robinson L, Verhelst A, Marzorati M, Winkens B, et al. A yeast fermentate improves gastrointestinal discomfort and constipation by modulation of the gut microbiome: results from a randomized double-blind placebo-controlled pilot trial. BMC Complement Altern Med. 2017;17:441. doi:10.1186/s12906-017-1948-0
- Cayzeele-Decherf A, Pélerin F, Leuillet S, Douillard B, Housez B, et al. CNCM I-3856 in irritable bowel syndrome: An individual subject meta-analysis. World J Gastroenterol. 2017;23:336. doi:10.3748/wjg.v23.i2.336
- Spiller R, Pélerin F, Cayzeele Decherf A, Maudet C, Housez B, et al. Randomized double blind placebo-controlled trial of Saccharomyces cerevisiae CNCM I-3856 in irritable bowel syndrome: improvement in abdominal pain and bloating in those with predominant constipation. United European Gastroenterol J. 2016;4:353. doi:10.1177/2050640615602571
- Alexandre V, Bertin C, Boubaya M, Airinei G, Bouchoucha M, et al. Randomized clinical trial: efficacy of a food supplement, TRANSITECH, on healthy individuals with mild intermittent constipation. Eur J Gastroenterol Hepatol. 2016;28:1087. doi:10.1097/MEG.0000000000000672
- Nakamura T, Agata K, Mizutani M, Iino H. Effects of brewer's yeast cell wall on constipation and defecation in experimentally constipated rats. Biosci Biotechnol Biochem. 2001;65:774.
