We investigated how a new blend of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001, along with vitamin B6, impacts bloating in patients with irritable bowel syndrome (IBS).
In a study involving 25 IBS patients, we found that those receiving this treatment experienced a significant reduction in bloating, with a 36.35% improvement compared to those on placebo, who actually experienced more bloating.
Overall, this formulation not only alleviated bloating but also eased abdominal pain and improved gut health, showcasing promising results for IBS symptom management.
Read More
8
Probiotic improves gastrointestinal symptoms
Validity and safety of ID-JPL934 in lower gastrointestinal symptom improvement.
We explored how the probiotic ID-JPL934, which includes Lactobacillus johnsonii and Bifidobacterium lactis, can relieve lower gastrointestinal symptoms, particularly bloating.
In a study with 112 participants, we compared those taking the probiotic against a placebo group. Results showed significant improvements in abdominal pain and bloating among those using ID-JPL934.
Moreover, we noted an increase in beneficial bacteria levels after treatment, suggesting that this probiotic might significantly enhance gut health and comfort.
Read More
8
Probiotics reduce bloating post-surgery
Effects of Probiotics Supplementation on Gastrointestinal Symptoms and SIBO after Roux-en-Y Gastric Bypass: a Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.
We explored the impact of probiotic supplementation on gastrointestinal issues following Roux-en-Y gastric bypass. In a well-structured trial, participants were divided into a group receiving Lactobacillus acidophilus and Bifidobacterium lactis and another receiving a placebo.
While both groups showed similar rates of small intestine bacterial overgrowth, those taking the probiotics reported significantly less bloating. They experienced some additional gastrointestinal symptoms but overall felt better in terms of bloating.
Ultimately, the probiotics were effective for managing bloating without affecting SIBO development.
Read More
Most Useful Reviews
7.5
Bloating relief
20 people found this helpful
I’ve used this product several times, and it truly works, regardless of age. At 55, I’ve noticed marked improvement in my gut health—my intestines feel at ease, bloating has disappeared, and my stool has normalised. The capsules are easy to take; I have one at night. I recommend this for anyone with gastrointestinal issues or who wants to boost their immunity.
Read More
9
Eliminated bloating
9 people found this helpful
I didn’t know that specific lactic acid bacteria existed for women until I started taking this as a pre-menopausal measure. The small, easy-to-swallow capsules really work, helping to eliminate bloating. After taking one tablet daily after dinner, I noticed natural regularity and significantly reduced odour and volume, which was surprising.
Read More
9
No more bloating
6 people found this helpful
These are the best women’s prebiotics! I've struggled with yeast infections, itching, and uncomfortable bloating, but after just two weeks of this supplement, I’ve had a positive response—no more itching, discharge, or yeast infections. It also alleviates bloating. It’s a bit pricey, and I need to refrigerate it, but I manage by using an ice pack during travel.
We investigated how cefixime and probiotics impact bloating in patients suffering from functional abdominal bloating (FAB). In a study involving 122 diagnosed patients, we compared three treatment groups: one receiving conventional treatment, a second with cefixime, and a third with probiotics.
Those treated with probiotics and cefixime saw notable improvements in their bloating sensations and abdominal distension compared to conventional methods. Interestingly, while symptoms like abdominal pain and bowel changes improved across all groups, the addition of probiotics and cefixime showed enhanced benefits.
Overall, these findings suggest that incorporating probiotics and cefixime may offer significant support for individuals struggling with bloating.
Read More
9
Lactobacillus reduces IBS bloating symptoms
Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients.
We investigated how a new blend of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001, along with vitamin B6, impacts bloating in patients with irritable bowel syndrome (IBS).
In a study involving 25 IBS patients, we found that those receiving this treatment experienced a significant reduction in bloating, with a 36.35% improvement compared to those on placebo, who actually experienced more bloating.
Overall, this formulation not only alleviated bloating but also eased abdominal pain and improved gut health, showcasing promising results for IBS symptom management.
Read More
9
Probiotics reduce pediatric AAD risk
Probiotics for the Prevention of Pediatric Antibiotic-Associated Diarrhea.
We analyzed data from 23 studies involving nearly 4,000 children to assess how probiotics help prevent antibiotic-associated diarrhea (AAD).
The results showed that those taking probiotics had an 8% incidence of AAD, compared to 19% in the control group, indicating a significant protective effect.
None of the trials documented serious adverse events from the probiotics, but some participants reported mild side effects like gas or bloating. Overall, probiotics such as Lactobacillus rhamnosus seem helpful in reducing AAD in children after antibiotic use.
Read More
9
Probiotics show promise for IBS
Effect of multispecies probiotics on irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial.
We explored the effects of multispecies probiotics, including Lactobacillus rhamnosus, on irritable bowel syndrome (IBS) symptoms like bloating. In a well-structured trial with 49 participants, those taking probiotics saw a significant reduction in IBS symptoms after 4 weeks compared to those on a placebo. Notably, 68% of the probiotics group reported substantial relief, showing promising results in reducing bloating and abdominal discomfort.
These findings suggest that taking multispecies probiotics could be beneficial for those struggling with IBS-related bloating and other symptoms.
Read More
9
APT036 outperforms simethicone in bloating
Efficacy and safety of APT036 versus simethicone in the treatment of functional bloating: a multicentre, randomised, double-blind, parallel group, clinical study.
We conducted a double-blind, randomized study to compare the effectiveness and safety of APT036, a combination treatment, and simethicone for functional bloating.
Over 20 days, participants took these treatments three times daily, with evaluations of their symptoms and abdominal girth at multiple points.
The results showed that APT036 significantly improved bloating symptoms, such as abdominal distension and flatulence, compared to simethicone, with both treatments being well tolerated and safe.
I’ve used this product several times, and it truly works, regardless of age. At 55, I’ve noticed marked improvement in my gut health—my intestines feel at ease, bloating has disappeared, and my stool has normalised. The capsules are easy to take; I have one at night. I recommend this for anyone with gastrointestinal issues or who wants to boost their immunity.
Read More
9
Eliminated bloating
9 people found this helpful
I didn’t know that specific lactic acid bacteria existed for women until I started taking this as a pre-menopausal measure. The small, easy-to-swallow capsules really work, helping to eliminate bloating. After taking one tablet daily after dinner, I noticed natural regularity and significantly reduced odour and volume, which was surprising.
Read More
9
No more bloating
6 people found this helpful
These are the best women’s prebiotics! I've struggled with yeast infections, itching, and uncomfortable bloating, but after just two weeks of this supplement, I’ve had a positive response—no more itching, discharge, or yeast infections. It also alleviates bloating. It’s a bit pricey, and I need to refrigerate it, but I manage by using an ice pack during travel.
Read More
9
Gas and bloating gone
6 people found this helpful
Great probiotic! The packaging holds plenty of small capsules. After just two weeks, I noticed a significant reduction in gas and bloating—no more embarrassing stomach noises. I’m very pleased with Fem Dophilus and have no regrets about my choice.
Read More
9
Feeling light
6 people found this helpful
Probiotic for women. This is one of the best probiotics I've taken! No taste at all and leaves you feeling light with no bloating. It's best taken before bed!
Bloating is a common gastrointestinal condition characterized by a sensation of fullness, tightness, or swelling in the abdomen. It often occurs after eating and can be accompanied by visible distension of the belly. This discomfort may be caused by various factors, including excessive gas production, food intolerances, overeating, or certain medical conditions affecting the digestive system. Many people experience bloating occasionally, but when it becomes chronic, it can significantly impact one's quality of life.
Managing bloating typically involves dietary adjustments, such as identifying and avoiding trigger foods, eating smaller meals, and incorporating more fiber into your diet. Staying hydrated and engaging in regular physical activity can also help alleviate symptoms. If bloating is persistent or accompanied by other troubling symptoms like severe pain or changes in bowel habits, it is advisable to consult a healthcare professional for proper evaluation and guidance.
Lactobacillus is a genus of bacteria that plays a crucial role in the fermentation of various foods and is found naturally in the human gut. Known for their probiotic properties, strains of Lactobacillus are commonly utilized in the production of yogurt, sauerkraut, and other fermented products. They are characterized by their rod-shaped structure and ability to convert sugars into lactic acid, which not only helps preserve food but also contributes to the tangy flavor of fermented foods.
In addition to their culinary uses, Lactobacillus bacteria can offer several health benefits. They are known to support gut health by enhancing the balance of beneficial bacteria in the microbiome, potentially aiding in digestion and alleviating symptoms of issues like irritable bowel syndrome (IBS). Regular consumption of Lactobacillus-containing foods or supplements may also bolster the immune system and improve overall digestive health. With a growing interest in gut health, Lactobacillus remains a key player in both dietary and therapeutic contexts.
Lactobacillus, a genus of beneficial bacteria found in many probiotic supplements and fermented foods, has been studied for its potential to alleviate bloating and promote digestive health. Research indicates that certain strains of Lactobacillus can help balance gut microbiota, which may lead to a reduction in bloating and other gastrointestinal discomfort. By improving the digestion of lactose and other foods, these probiotics can enhance nutrient absorption, potentially minimizing gas production and bloating in susceptible individuals.
While individual responses to probiotics can vary, many users report positive effects after incorporating Lactobacillus strains into their diets. Options like yogurt, kefir, and over-the-counter probiotic supplements are popular choices for those looking to harness the power of these helpful bacteria. However, it’s essential to choose the right strain; for example, Lactobacillus rhamnosus and Lactobacillus plantarum have shown promise in various studies. As with any supplement regimen, it’s advisable to consult with a healthcare provider to determine the best approach tailored to your digestive health needs.
Based on user reviews, individuals typically report noticing results for bloating relief within a range of a few days to several weeks after starting to take the supplement. For instance, one user mentioned significant improvement in their bloating after just a few days of use Read Review. Another noted a substantial reduction in gas and bloating after two weeks Read Review. Additionally, some users indicated that improvements in gut health became pronounced around the second week of use, highlighting the efficacy they experienced Read Review.
Overall, while results can vary from person to person, the consensus seems to suggest that consistent use over a period of one to two weeks is where many people begin to experience noticeable relief from bloating. For those who struggle with gastrointestinal discomfort, regular intake and patience might yield positive outcomes Read Review.
When it comes to managing bloating, scientific research suggests that certain probiotics can provide notable relief. For instance, a study involving patients with functional abdominal bloating demonstrated significant improvements in bloating sensations for those who took probiotics along with cefixime compared to conventional treatment methods [1]. Additionally, Lactobacillus plantarum, commonly used in probiotic supplements, has also been linked to reduced bloating in patients undergoing iron therapy, indicating its potential effectiveness in various contexts [2].
Moreover, other specific probiotic strains have shown promise in mitigating bloating symptoms. Research focused on IBS patients found that certain Lactobacillus and Bifidobacterium strains can improve bloating and intestinal comfort [4]. Specifically, Lactobacillus reuteri and Lactobacillus rhamnosus have been indicated in trials to significantly reduce bloating and related discomfort, with one study revealing a 36% improvement in bloating among IBS patients after treatment with these probiotics [12]. Overall, there is substantial support for the use of certain probiotics in alleviating bloating, making them a worthwhile consideration for those seeking relief.
Users have reported considerable improvements in digestive symptoms after using this probiotic supplement. Many individuals noted a marked reduction in bloating, with one user mentioning that their bloating, which persisted for three months, finally subsided after starting the product Read Review. Another user, who had experienced discomfort after meals, observed significant relief, stating that the product has been a "lifesaver" for their gut health Read Review. These positive experiences resonate across various demographics, as mentioned by a 55-year-old user who felt their gut health improved significantly after using the product Read Review.
Several reviews highlighted improvements in regularity and overall digestive comfort. For example, a user with previous issues of constipation reported having more frequent bowel movements and a cessation of painful sensations after just a few days Read Review. Additionally, individuals reported enhanced energy levels and fewer embarrassing stomach noises, contributing to an overall sense of well-being and balance Read Review. While individual results can vary, the consensus among users suggests that this probiotic may effectively help manage digestive concerns, offering hope for others facing similar issues.
Users have reported positive interactions when combining this probiotic supplement with other dietary supplements for managing bloating. One review noted that taking this product alongside NOW Foods Candida Support significantly improved gut health, reducing bloating and discomfort Read Review. Another reviewer shared their experience using peppermint oil in conjunction with the probiotic for several months, noting some improvement in bloating, although they ultimately found dietary adjustments more effective Read Review.
Several users have emphasized the importance of consistency in using these supplements to achieve optimal results. It appears from reviews that while combining supplements like peppermint oil or specifically targeting products such as Candida support may enhance the effectiveness against bloating, individual results can vary. Some users also pointed out that adjusting their overall diet was a crucial factor in addressing their bloating issues, alongside taking these probiotics Read Review.
Based on user reviews, finding the right dose of Lactobacillus for treating bloating typically involves taking one capsule daily, often after dinner. For instance, one user mentioned taking one tablet daily, which helped to significantly reduce bloating and improve regularity in her digestive health Read Review. Another reviewer also reported that taking one capsule daily for weeks resulted in improved digestion and reduced bloating, enhancing their overall feeling of comfort and energy Read Review.
Consumers noted consistently experiencing better gut health and alleviated bloating symptoms when adhering to this dosing regimen. Additionally, several reviews underscored that consistent use over a few weeks was vital for optimal results, suggesting that users may need to commit to this daily routine for best results Read Review. This information indicates that while individual results may vary, a common approach involves taking one Lactobacillus capsule per day to effectively manage and reduce bloating.
9
Bloating relieved
After a few days of use, my bloating issue has improved significantly, and my constipation problems have also been resolved.
9
Gas and bloating gone
6 people found this helpful
Great probiotic! The packaging holds plenty of small capsules. After just two weeks, I noticed a significant reduction in gas and bloating—no more embarrassing stomach noises. I’m very pleased with Fem Dophilus and have no regrets about my choice.
9
No more bloating
6 people found this helpful
These are the best women’s prebiotics! I've struggled with yeast infections, itching, and uncomfortable bloating, but after just two weeks of this supplement, I’ve had a positive response—no more itching, discharge, or yeast infections. It also alleviates bloating. It’s a bit pricey, and I need to refrigerate it, but I manage by using an ice pack during travel.
9
No more bloating
I chose this product from iHerb to change my lactic acid bacteria. It works well, and I no longer feel bloated. While I plan to take more, I've been satisfied after a month of use.
9
Bloating eliminated
1 people found this helpful
I recommend this; the bloating in my lower abdomen, which persisted for nearly three months, has finally subsided.
8
Effective probiotic
2 people found this helpful
This has been a lifesaver for my gut! Bloating and discomfort after meals have significantly reduced. After searching for an effective probiotic, I finally found one that works, and I highly recommend it.
7.5
Bloating relief
20 people found this helpful
I’ve used this product several times, and it truly works, regardless of age. At 55, I’ve noticed marked improvement in my gut health—my intestines feel at ease, bloating has disappeared, and my stool has normalised. The capsules are easy to take; I have one at night. I recommend this for anyone with gastrointestinal issues or who wants to boost their immunity.
9
Normalised bowel function
4 people found this helpful
This prebiotic is excellent! By the second week, I felt improvements by the third day. I previously faced issues with regularity but now, bowel movements occur 3-5 times a day. The burning sensation has stopped, bloating is gone, and there are no more instances of constipation, making me feel much better overall.
7.5
Reduced discomfort
1 people found this helpful
This is a good probiotic for women. I take it alongside NOW Foods Candida Support, and I have noticed a significant improvement in my gut health, with reduced bloating and discomfort. While my candida situation is better, it's not yet perfect. I believe consistent use for a couple of months will provide a clear effect.
6
No significant effect
I bought this due to severe bloating from gas. After taking it alongside peppermint oil for three to four months, I noticed some improvement. However, I won’t repurchase as adjusting my diet proved more effective, and it did not alleviate my constipation significantly.
6
Unsatisfactory results
I experienced severe bloating from gas and took this for four months. It had some effect but was not satisfactory. Adjusting my diet helped more, and it did little for constipation. Although the brand is reliable and the product is easy to consume, I recommend consistent use for better results.
9
Eliminated bloating
9 people found this helpful
I didn’t know that specific lactic acid bacteria existed for women until I started taking this as a pre-menopausal measure. The small, easy-to-swallow capsules really work, helping to eliminate bloating. After taking one tablet daily after dinner, I noticed natural regularity and significantly reduced odour and volume, which was surprising.
9
Less bloating
After taking one capsule daily for weeks, I feel my digestion has improved and bloating has decreased. My gut seems more efficient, making me feel lighter and more comfortable. I'm also more energetic. The vegan-friendly capsules are easy to swallow, with no unpleasant aftertaste.
9
Cefixime and probiotics enhance bloating relief
Impact of cefixime and probiotics on functional abdominal bloating: a pilot study.
We investigated how cefixime and probiotics impact bloating in patients suffering from functional abdominal bloating (FAB). In a study involving 122 diagnosed patients, we compared three treatment groups: one receiving conventional treatment, a second with cefixime, and a third with probiotics.
Those treated with probiotics and cefixime saw notable improvements in their bloating sensations and abdominal distension compared to conventional methods. Interestingly, while symptoms like abdominal pain and bowel changes improved across all groups, the addition of probiotics and cefixime showed enhanced benefits.
Overall, these findings suggest that incorporating probiotics and cefixime may offer significant support for individuals struggling with bloating.
8
Lactobacillus aids iron therapy tolerance
Improved gastrointestinal tolerance and iron status via probiotic use in iron deficiency anaemia patients initiating oral iron replacement: a randomised controlled trial.
We examined how Lactobacillus plantarum 299v impacts patients with iron deficiency anemia who were starting oral iron replacement therapy. In our research with 295 participants, those who took the probiotic alongside their iron therapy reported significantly less bloating and other gastrointestinal issues.
This led to better treatment adherence, with fewer individuals stopping their iron therapy early. Additionally, the probiotic users showed improved iron levels and hemoglobin readings after three months. Overall, Lactobacillus proved effective in easing bloating and supporting gastrointestinal comfort during iron treatment.
7
Probiotics offer selective benefits
Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis.
We explored the effectiveness of various probiotic strains and mixtures for treating bloating in individuals with irritable bowel syndrome (IBS). Our analysis comprised data from 81 randomized controlled trials, involving 9,253 participants.
While multiple probiotics proved beneficial for specific IBS symptoms, only three strains and two mixtures demonstrated effectiveness in alleviating abdominal bloating.
Notably, while some probiotics showed promise, results varied, indicating that not all strains are equally effective for every symptom. Further investigations are required to strengthen these findings.
9
Lactobacillus reduces IBS bloating symptoms
Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients.
We investigated how a new blend of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001, along with vitamin B6, impacts bloating in patients with irritable bowel syndrome (IBS).
In a study involving 25 IBS patients, we found that those receiving this treatment experienced a significant reduction in bloating, with a 36.35% improvement compared to those on placebo, who actually experienced more bloating.
Overall, this formulation not only alleviated bloating but also eased abdominal pain and improved gut health, showcasing promising results for IBS symptom management.
References
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Koker G, Sahinturk Y, Ozcelik Koker G, Coskuner MA, Eren Durmus M, et al. Improved gastrointestinal tolerance and iron status via probiotic use in iron deficiency anaemia patients initiating oral iron replacement: a randomised controlled trial. Br J Nutr. 2024;132:1308. doi:10.1017/S0007114524002757
Yang H, Lan W, Luo C, Huang Q, Zhong Z, et al. improves postoperative bloating and hard stools by modulating intestinal microbiota in patients with congenital heart disease: a randomized controlled trial. Food Funct. 2024;15:2090. doi:10.1039/d3fo05452g
Xie P, Luo M, Deng X, Fan J, Xiong L. Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis. Nutrients. 2023;15. doi:10.3390/nu15173856
Vorobieva OA, Shih EV, Drozdov VN, Shikh NV. [The results of the use of a combined probiotic ( and spp. ВB-12) in children with gastrointestinal and skin manifestations of food allergy]. Vopr Pitan. 2023;92:79. doi:10.33029/0042-8833-2023-92-3-79-86
Deleemans JM, Gajtani Z, Baydoun M, Reimer RA, Piedalue KA, et al. The Use of Prebiotic and Probiotic Interventions for Treating Gastrointestinal and Psychosocial Health Symptoms in Cancer Patients and Survivors: A Systematic Review. Integr Cancer Ther. 2021;20:15347354211061733. doi:10.1177/15347354211061733
Oh YJ, Nam K, Kim Y, Lee SY, Kim HS, et al. Effect of a Nutritionally Balanced Diet Comprising Whole Grains and Vegetables Alone or in Combination with Probiotic Supplementation on the Gut Microbiota. Prev Nutr Food Sci. 2021;26:121. doi:10.3746/pnf.2021.26.2.121
Shin CM, Choi YJ, Lee DH, Moon JS, Kim TY, et al. Validity and safety of ID-JPL934 in lower gastrointestinal symptom improvement. Sci Rep. 2021;11:13046. doi:10.1038/s41598-021-92007-3
Wagner NRF, Ramos MRZ, de Oliveira Carlos L, da Cruz MRR, Taconeli CA, et al. Effects of Probiotics Supplementation on Gastrointestinal Symptoms and SIBO after Roux-en-Y Gastric Bypass: a Prospective, Randomized, Double-Blind, Placebo-Controlled Trial. Obes Surg. 2021;31:143. doi:10.1007/s11695-020-04900-x
Fatani A, Vaher K, Rivero-Mendoza D, Alabasi K, Dahl WJ. Fermented soy supplementation improves indicators of quality of life: a randomized, placebo-controlled, double-blind trial in adults experiencing heartburn. BMC Res Notes. 2020;13:364. doi:10.1186/s13104-020-05205-z
Maixent JM, Pons O, Sennoune SR, Sadrin S. Clinical effects of Lactobacillus strains as probiotics in the treatment of irritable bowel syndrome. Results from the LAPIBSS trial: Future objectives. Cell Mol Biol (Noisy-le-grand). 2020;66:211.
Bonfrate L, Di Palo DM, Celano G, Albert A, Vitellio P, et al. Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients. Eur J Clin Invest. 2020;50:e13201. doi:10.1111/eci.13201
Sadrin S, Sennoune S, Gout B, Marque S, Moreau J, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis. 2020;52:534. doi:10.1016/j.dld.2019.12.009
Wang MC, Zaydi AI, Lin WH, Lin JS, Liong MT, et al. Putative Probiotic Strains Isolated from Kefir Improve Gastrointestinal Health Parameters in Adults: a Randomized, Single-Blind, Placebo-Controlled Study. Probiotics Antimicrob Proteins. 2020;12:840. doi:10.1007/s12602-019-09615-9
Lai HH, Chiu CH, Kong MS, Chang CJ, Chen CC. Probiotic : Effective for Managing Childhood Diarrhea by Altering Gut Microbiota and Attenuating Fecal Inflammatory Markers. Nutrients. 2019;11. doi:10.3390/nu11051150
Vitellio P, Celano G, Bonfrate L, Gobbetti M, Portincasa P, et al. Effects of and on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study. Nutrients. 2019;11. doi:10.3390/nu11040886
Kwon H, Nam EH, Kim H, Jo H, Bang WY, et al. Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial. Sci Rep. 2024;14:22384. doi:10.1038/s41598-024-72887-x
Hayes SR, Vargas AJ. Probiotics for the Prevention of Pediatric Antibiotic-Associated Diarrhea. Explore (NY). 2016;12:463. doi:10.1016/j.explore.2016.08.015
Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, et al. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev. 2015. doi:10.1002/14651858.CD004827.pub4
Hauser G, Salkic N, Vukelic K, JajacKnez A, Stimac D. Probiotics for standard triple Helicobacter pylori eradication: a randomized, double-blind, placebo-controlled trial. Medicine (Baltimore). 2015;94:e685. doi:10.1097/MD.0000000000000685
Yoon JS, Sohn W, Lee OY, Lee SP, Lee KN, et al. Effect of multispecies probiotics on irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Gastroenterol Hepatol. 2014;29:52. doi:10.1111/jgh.12322
Molin G. Probiotics in foods not containing milk or milk constituents, with special reference to Lactobacillus plantarum 299v. Am J Clin Nutr. 2001;73:380S. doi:10.1093/ajcn/73.2.380s
Burta O, Iacobescu C, Mateescu RB, Nicolaie T, Tiuca N, et al. Efficacy and safety of APT036 versus simethicone in the treatment of functional bloating: a multicentre, randomised, double-blind, parallel group, clinical study. Transl Gastroenterol Hepatol. 2018;3:72. doi:10.21037/tgh.2018.09.11
Riezzo G, Orlando A, D'Attoma B, Linsalata M, Martulli M, et al. Randomised double blind placebo controlled trial on Lactobacillus reuteri DSM 17938: improvement in symptoms and bowel habit in functional constipation. Benef Microbes. 2018;9:51. doi:10.3920/BM2017.0049
Weizman Z, Abu-Abed J, Binsztok M. Lactobacillus reuteri DSM 17938 for the Management of Functional Abdominal Pain in Childhood: A Randomized, Double-Blind, Placebo-Controlled Trial. J Pediatr. 2016;174:160. doi:10.1016/j.jpeds.2016.04.003