Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.8
USERS' SCORE
Moderately Good
Based on 12 Reviews
7.8
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Proprietary Probiotic Blend
134 mg (1 Billion CFU§)
†
Lactobacillus rhamnosus (GR-1®)
Lactobacillus reuteri (RC-14®)
Top Medical Research Studies
9
We investigated the effects of Limosilactobacillus fermentum (L. fermentum) KBL674 on vaginal candidiasis in a mouse model. This strain inhibited the growth of Candida albicans and significantly decreased infection symptoms. Notably, the oral intake of L. fermentum KBL674 influenced both vaginal and gut microbiome health, promoting beneficial bacteria that seemed to correlate with reduced C. albicans levels. Thus, L. fermentum KBL674 shows promise for managing vaginal candidiasis by enhancing gut microbiome diversity and lowering fungal burden.
Read More
9
We conducted a rigorous study to investigate the impact of lactobacillus probiotics on pregnant women suffering from vaginal candidiasis. In this double-blind, placebo-controlled trial involving 78 participants, we administered a probiotic for eight weeks.
Our results highlighted significant benefits, with the probiotics maintaining microbiota stability in the vagina and gut, unlike the placebo group. Participants taking probiotics showed less variation in their microbiota, which is crucial for overall health. While the treatment showed promise in preserving microbiota composition, individual experiences may vary.
Our results highlighted significant benefits, with the probiotics maintaining microbiota stability in the vagina and gut, unlike the placebo group. Participants taking probiotics showed less variation in their microbiota, which is crucial for overall health. While the treatment showed promise in preserving microbiota composition, individual experiences may vary.
Read More
4
Lactobacillus shows promise for candidiasis
We assessed how well Lactobacillus plantarum P 17630 works against vaginal candidiasis compared to traditional antifungal treatments like miconazole. In a controlled trial, women with candidiasis took either Lactobacillus capsules or miconazole capsules for several days. Results showed that both treatments reduced vaginitis symptoms over time, with no significant differences. Importantly, Lactobacillus treatment did not lead to any adverse effects and may foster healthier vaginal flora in the long run, potentially decreasing recurring infections.
Read More
Most Useful Reviews
9
Relief after two weeks
6 people found this helpful
I struggled with recurrent candidiasis, and this product has been extremely helpful. I noticed an improvement in just two weeks after searching for an effective solution for over two years. The delivery to Brazil was swift as well, so I plan to buy it more often.
Read More
9
Candidiasis problem solved
4 people found this helpful
My friend recommended this as probiotics are known to help reduce Candida infections. This product resolved my candidiasis problem! I've been using it for three months now, and I'm pleased to say the issue is resolved.
Read More
0
Symptoms returned rapidly
3 people found this helpful
After taking antibiotics, I experienced mild candidiasis and started using this product. I took four capsules and everything disappeared. However, after I stopped taking it, the symptoms returned when I resumed. I won’t continue with it anymore.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.8
- All Researches
9.5
This study looked at Lactobacillus gasseri VHProbi E09, a strain shown to effectively inhibit harmful bacteria like Gardnerella vaginalis and Candida albicans, key players in vaginitis. We found that this strain could cut the growth of both pathogens by an impressive 99%, while also preventing their attachment to vaginal cells.
What’s exciting is the potential of L. gasseri VHProbi E09 as a probiotic for improving vaginal health, either taken orally or applied directly. However, more research is needed to fully explore its effects and effectiveness in restoring balance in the vaginal ecosystem.
What’s exciting is the potential of L. gasseri VHProbi E09 as a probiotic for improving vaginal health, either taken orally or applied directly. However, more research is needed to fully explore its effects and effectiveness in restoring balance in the vaginal ecosystem.
Read More
9
Identified lactobacillus metabolites inhibit Candida
Through innovative techniques like genome-scale metabolic modeling and metagenomic sequencing, we discovered the role of specific lactobacillus strains in combating vulvovaginal candidiasis (VVC).
Our analysis of 159 strains showed that many have inhibitory effects on Candida, altering its metabolism through key metabolites like L-lactate and formate. Interestingly, we found a positive link between the presence of these beneficial strains and lower Candida levels in vaginal samples.
This research informs future strategies focused on enhancing vaginal health by utilizing these powerful strains and their metabolites to hinder candidiasis.
Our analysis of 159 strains showed that many have inhibitory effects on Candida, altering its metabolism through key metabolites like L-lactate and formate. Interestingly, we found a positive link between the presence of these beneficial strains and lower Candida levels in vaginal samples.
This research informs future strategies focused on enhancing vaginal health by utilizing these powerful strains and their metabolites to hinder candidiasis.
Read More
9
We investigated the potential of a newly isolated probiotic, AJCR4, to combat oral candidiasis, a common infection, particularly among immunocompromised individuals. AJCR4 showed strong antifungal effects against both free and biofilm forms of Candida, with impressive results in reducing viable cells in lab tests. In specific biofilms, we observed over 2-log reductions in cell counts. This promising performance suggests that AJCR4 could serve as an effective alternative strategy for treating difficult oral candidiasis cases, especially recurrent infections.
Read More
9
We investigated the effects of a novel fermentation broth called VAGINNE on vulvovaginal candidiasis (VVC), a common condition affecting many women. Using a mouse model, we found that VAGINNE not only boosted beneficial bacteria but also suppressed the growth of Candida, promoting a healthier vaginal environment.
Additionally, VAGINNE significantly decreased inflammation markers, which is essential for tissue health. This promising approach suggests VAGINNE could be a valuable alternative to traditional antifungals, especially for women facing drug resistance or side effects from standard treatments.
Additionally, VAGINNE significantly decreased inflammation markers, which is essential for tissue health. This promising approach suggests VAGINNE could be a valuable alternative to traditional antifungals, especially for women facing drug resistance or side effects from standard treatments.
Read More
9
We explored how combining oral probiotics with standard antifungal treatment affects vulvovaginal candidiasis (VVC). In a randomized controlled trial involving 60 patients, we compared results between those receiving antifungal medication alone and those receiving it alongside probiotics.
The results were promising! Participants who took probiotics showed better clinical and mycological outcomes, along with a reduced rate of relapse compared to those on antifungal treatment alone. This suggests that probiotics may be a valuable addition to VVC management.
The results were promising! Participants who took probiotics showed better clinical and mycological outcomes, along with a reduced rate of relapse compared to those on antifungal treatment alone. This suggests that probiotics may be a valuable addition to VVC management.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 12 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Relief after two weeks
6 people found this helpful
I struggled with recurrent candidiasis, and this product has been extremely helpful. I noticed an improvement in just two weeks after searching for an effective solution for over two years. The delivery to Brazil was swift as well, so I plan to buy it more often.
Read More
9
Candidiasis problem solved
4 people found this helpful
My friend recommended this as probiotics are known to help reduce Candida infections. This product resolved my candidiasis problem! I've been using it for three months now, and I'm pleased to say the issue is resolved.
Read More
0
Symptoms returned rapidly
3 people found this helpful
After taking antibiotics, I experienced mild candidiasis and started using this product. I took four capsules and everything disappeared. However, after I stopped taking it, the symptoms returned when I resumed. I won’t continue with it anymore.
Read More
10
Eliminated itching
Very good! It helped me feel no itchiness, and I am clear of candidiasis now.
Read More
10
Restored condition
This definitely works; after taking antibiotics for ten days, my condition is restored and the microflora stabilises, resulting in complete disappearance of candidiasis. It's an excellent drug.
Read More
Frequently Asked Questions
9
Relief after two weeks
6 people found this helpful
I struggled with recurrent candidiasis, and this product has been extremely helpful. I noticed an improvement in just two weeks after searching for an effective solution for over two years. The delivery to Brazil was swift as well, so I plan to buy it more often.
9
Candidiasis problem solved
4 people found this helpful
My friend recommended this as probiotics are known to help reduce Candida infections. This product resolved my candidiasis problem! I've been using it for three months now, and I'm pleased to say the issue is resolved.
0
Symptoms returned rapidly
3 people found this helpful
After taking antibiotics, I experienced mild candidiasis and started using this product. I took four capsules and everything disappeared. However, after I stopped taking it, the symptoms returned when I resumed. I won’t continue with it anymore.
7.5
Maintains health
Fem-Dophilus contains two strains of lactobacilli that help populate the vagina with beneficial microflora, improving the urinary tract microbiome. Their primary role is to maintain an acidic environment, suppressing pathogenic flora. They are effective against vaginosis, candidiasis, and are beneficial during pregnancy when preparing the birth canal. For best results, take orally for at least a month. Excellent quality.
10
Eliminated itching
Very good! It helped me feel no itchiness, and I am clear of candidiasis now.
2
Ineffective treatment
Unfortunately, this product didn’t help me. I used it a couple of times, but candidiasis recurred every few days.
9
Immediate relief
The best female probiotic I've ever used! I often get vaginitis after my period, and candidiasis when I'm fatigued. Whenever I notice an odd odour or feel unwell, I take this and sleep, and it improves immediately! It's truly remarkable, especially when taken with vitamin C and inulin.
9
Probiotics worked well
This is an excellent probiotic; my relapses of candidiasis have ceased. The microflora has been perfectly restored, which has greatly improved my health.
8
Improvement noted
My candidiasis has significantly improved since I started consuming this product regularly.
9
We explored how combining oral probiotics with standard antifungal treatment affects vulvovaginal candidiasis (VVC). In a randomized controlled trial involving 60 patients, we compared results between those receiving antifungal medication alone and those receiving it alongside probiotics.
The results were promising! Participants who took probiotics showed better clinical and mycological outcomes, along with a reduced rate of relapse compared to those on antifungal treatment alone. This suggests that probiotics may be a valuable addition to VVC management.
The results were promising! Participants who took probiotics showed better clinical and mycological outcomes, along with a reduced rate of relapse compared to those on antifungal treatment alone. This suggests that probiotics may be a valuable addition to VVC management.
9
LM1215 shows promise for VVC prevention
We observed three specific strains of Lactobacillus, namely LM1203, LM1209, and LM1215, that displayed promising results in inhibiting vulvovaginal candidiasis (VVC). Isolated from healthy women, these strains significantly reduced the growth of harmful pathogens.
In addition, LM1215 showed remarkable ability to disrupt biofilms and induce cellular damage against these pathogens. Our findings suggest that LM1215 is not only effective but also safe, positioning it as a viable probiotic option for preventing VVC and bacterial vaginosis.
In addition, LM1215 showed remarkable ability to disrupt biofilms and induce cellular damage against these pathogens. Our findings suggest that LM1215 is not only effective but also safe, positioning it as a viable probiotic option for preventing VVC and bacterial vaginosis.
9
We investigated the effects of Limosilactobacillus fermentum (L. fermentum) KBL674 on vaginal candidiasis in a mouse model. This strain inhibited the growth of Candida albicans and significantly decreased infection symptoms. Notably, the oral intake of L. fermentum KBL674 influenced both vaginal and gut microbiome health, promoting beneficial bacteria that seemed to correlate with reduced C. albicans levels. Thus, L. fermentum KBL674 shows promise for managing vaginal candidiasis by enhancing gut microbiome diversity and lowering fungal burden.
2
We aimed to understand whether oral probiotics could help pregnant women prevent recurrent vulvovaginal infections (VVIs). In a well-structured multicenter trial, women who previously treated infections were divided into two groups: one received a probiotic formula while the other got a placebo.
After monitoring for nearly four months, we found no significant difference in VVI recurrence rates between the two groups. This indicates that the tested oral probiotics did not effectively reduce the occurrence of VVIs in pregnant women.
After monitoring for nearly four months, we found no significant difference in VVI recurrence rates between the two groups. This indicates that the tested oral probiotics did not effectively reduce the occurrence of VVIs in pregnant women.
References
- Hu T, Meng Y, Zhao C, Sheng D, Yang S, et al. Genome-scale metabolic modeling reveals specific vaginal strains and their metabolites as key inhibitors of . Microbiol Spectr. 2025. doi:10.1128/spectrum.02984-24
- Nachum Z, Suleiman A, Colodner R, Battino S, Wattad M, et al. Oral Probiotics to Prevent Recurrent Vulvovaginal Infections During Pregnancy-Multicenter Double-Blind, Randomized, Placebo-Controlled Trial. Nutrients. 2025;17. doi:10.3390/nu17030460
- Rajão A, Silva JPN, Almeida-Nunes DL, Rompante P, Rodrigues CF, et al. AJCR4: A Potential Probiotic in the Fight Against Oral spp. Biofilms. Int J Mol Sci. 2025;26. doi:10.3390/ijms26020638
- Horng HC, Xu JW, Kuo YS, Chen YS, Chiu YH, et al. Dual Mechanisms of Action: Anti-Candida and Anti-Inflammatory Potential of Fermentation Broth in Treating Vulvovaginal Candidiasis. J Fungi (Basel). 2024;11. doi:10.3390/jof11010018
- Thekho AJ, Mendiratta V, Garg T, Kaur R, Yadav V. Role of Probiotic in Vulvovaginal Candidiasis: A Randomised Controlled Non-blinded Trial from India. Indian J Dermatol. 2024;69:422. doi:10.4103/ijd.ijd_193_24
- Bae WY, Lee YJ, Jo S, Shin SL, Kim TR, et al. Effects of LM1215 on and . Yonsei Med J. 2024;65:727. doi:10.3349/ymj.2023.0490
- Jang SJ, Jo EJ, Lee C, Cho BR, Shin YJ, et al. Limosilactobacillus fermentum KBL674 Alleviates Vaginal Candidiasis. Probiotics Antimicrob Proteins. 2024. doi:10.1007/s12602-024-10403-3
- Ferreira RLPS, Nova BGV, Carmo MS, Abreu AG. Mechanisms of action of Lactobacillus spp. in the treatment of oral candidiasis. Braz J Biol. 2024;84:e282609. doi:10.1590/1519-6984.282609
- Vazquez-Munoz R, Thompson A, Sobue T, Dongari-Bagtzoglou A. is a dominant in the murine oral mucosa and has chitinase activity that compromises fungal cell wall integrity. mBio. 2024;15:e0241624. doi:10.1128/mbio.02416-24
- Zuñiga Vinueza AM. Probiotics for the Prevention of Vaginal Infections: A Systematic Review. Cureus. 2024;16:e64473. doi:10.7759/cureus.64473
- Zhang J, Li K, Cao T, Duan Z. Characterization of a Lactobacillus gasseri strain as a probiotic for female vaginitis. Sci Rep. 2024;14:14426. doi:10.1038/s41598-024-65550-y
- Elsayes SA, El Attar MS, ElHadary A, Aboulela AG, Essawy MM, et al. Antimycotic prophylaxis with multispecies probiotics against oral candidiasis in new complete denture wearers: A randomized clinical trial. J Prosthet Dent. 2024. doi:10.1016/j.prosdent.2024.05.018
- Zahedifard T, Khadivzadeh T, Rakhshkhorshid M. The Role of Probiotics in the Treatment of Vulvovaginal Candidiasis: A Systematic Review and Meta-Analysis. Ethiop J Health Sci. 2023;33:881. doi:10.4314/ejhs.v33i5.18
- Ang XY, Roslan NS, Ahmad N, Yusof SM, Abdullah N, et al. Lactobacillus probiotics restore vaginal and gut microbiota of pregnant women with vaginal candidiasis. Benef Microbes. 2023;14:421. doi:10.1163/18762891-20220103
- Bertarello C, Savio D, Morelli L, Bouzalov S, Davidova D, et al. Efficacy and safety of Lactobacillus plantarum P 17630 strain soft vaginal capsule in vaginal candidiasis: a randomized non-inferiority clinical trial. Eur Rev Med Pharmacol Sci. 2024;28:384. doi:10.26355/eurrev_202401_34927
- Faustino M, Pereira JO, Pereira AM, Oliveira AS, Ferreira CMH, et al. Vaginal prevention of Candida albicans: synergistic effect of lactobacilli and mannan oligosaccharides (MOS). Appl Microbiol Biotechnol. 2024;108:73. doi:10.1007/s00253-023-12909-2
