Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8.3
USERS' SCORE
Good
Based on 13 Reviews
8.2
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Proprietary Probiotic Blend
134 mg (1 Billion CFU§)
†
Lactobacillus rhamnosus (GR-1®)
Lactobacillus reuteri (RC-14®)
Top Medical Research Studies
9
Lactobacillus reduces atherosclerosis risk
We aimed to explore whether Lactobacillus rhamnosus GG (LGG) could help combat atherosclerosis (AS) in mice. In a controlled study, we administered LGG to ApoE mice and compared their outcomes to control groups.
After 15 weeks, we discovered that LGG significantly reduced AS by lowering oxidative stress and inflammation, likely through activating specific pathways.
Additionally, LGG improved the gut microbiota, aligning it more closely with healthier control mice, which may enhance its heart protection benefits further.
After 15 weeks, we discovered that LGG significantly reduced AS by lowering oxidative stress and inflammation, likely through activating specific pathways.
Additionally, LGG improved the gut microbiota, aligning it more closely with healthier control mice, which may enhance its heart protection benefits further.
Read More
9
We focused on the potential benefits of Lactobacillus supplementation in helping mitigate damage from ischemic stroke. Our study involved testing two specific strains, G89 and G133, in mice with induced strokes.
Notably, we observed that both strains helped reduce brain injury and improve recovery. They maintained gut barrier integrity and lowered inflammation. These findings suggest that probiotics could play a significant role in stroke treatment by influencing gut-brain-spleen communication.
Notably, we observed that both strains helped reduce brain injury and improve recovery. They maintained gut barrier integrity and lowered inflammation. These findings suggest that probiotics could play a significant role in stroke treatment by influencing gut-brain-spleen communication.
Read More
8
We investigated how Aucubin, a natural compound from Eucommia ulmoides, impacts atherosclerosis (AS) by influencing gut microbiota. Through detailed studies in ApoE mice and fecal microbiota transplants, we found that Aucubin reduced dyslipidemia and endothelial dysfunction in a dose-dependent manner.
Significantly, we noted an increase in Lactobacillus and its metabolite, indole-3-acrylic acid (IAA), which played a vital role in easing AS. While the findings highlight Aucubin’s promising anti-atherosclerotic effects, it remains essential to explore further implications for cardiovascular health.
Significantly, we noted an increase in Lactobacillus and its metabolite, indole-3-acrylic acid (IAA), which played a vital role in easing AS. While the findings highlight Aucubin’s promising anti-atherosclerotic effects, it remains essential to explore further implications for cardiovascular health.
Read More
Most Useful Reviews
9
Long-lasting relief
15 people found this helpful
Thrush winner! I read in one of the books in the "Elements" series of the "Dynasty" project about the bacterium Lactobacillus rhamnosus, which helps women manage gynecological diseases. After oncology and surgery, my microflora was disturbed, causing discomfort and thrush. I found "Fem Dophilus" on IHerb, which contains Lactobacillus rhamnosus and Lactobacillus reuteri. I took two courses with a month's break, and within two weeks I noticed improvement. Several years later, none of my problems have returned, and I recommended it to friends and family, who have all benefited.
Read More
9
Candida-free
4 people found this helpful
Very good! I've repurchased many times! It has an absolute effect on Candida! I face fewer body issues, and I'm now free from the disease. I take three capsules of Jarrow Formulas Fem Dophilus each night. With 60 vegetarian capsules and an additional California Gold Nutrition LactoBif Probiotic, I experience no discomfort. I've made multiple purchases from Hong Kong—if you find my comment useful, please give me a like. Thanks!
Read More
9
Life-changing product
This nutrient has become an essential part of my health routine! A friend recommended it years ago after she suffered from female issues like cystitis, which caused me considerable trouble at times. I have had to visit the emergency room early due to cystitis, but I was amazed at how quickly my symptoms improved with Jarrow Pamdophilus and cranberry supplements. The small pill size makes it easy to swallow and carry when travelling. I’ve also noticed benefits to my digestive health due to the lactic acid bacteria—very effective!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8.3
- All Researches
9
We investigated how nonsurgical periodontal treatment (NSPT) affects levels of trimethylamine n-oxide (TMAO), a factor linked to cardiovascular disease, in Apoe mice diagnosed with periodontitis.
In our study, NSPT significantly lowered TMAO levels compared to untreated mice. We observed shifts in gut bacteria communities post-treatment, including changes in Lactobacillus and other species linked to TMAO metabolism.
Overall, our findings suggest that NSPT can help mitigate periodontitis' negative effects on cardiovascular health by improving TMAO metabolism and gut microbiota.
In our study, NSPT significantly lowered TMAO levels compared to untreated mice. We observed shifts in gut bacteria communities post-treatment, including changes in Lactobacillus and other species linked to TMAO metabolism.
Overall, our findings suggest that NSPT can help mitigate periodontitis' negative effects on cardiovascular health by improving TMAO metabolism and gut microbiota.
Read More
9
Lactobacillus reduces atherosclerosis risk
We aimed to explore whether Lactobacillus rhamnosus GG (LGG) could help combat atherosclerosis (AS) in mice. In a controlled study, we administered LGG to ApoE mice and compared their outcomes to control groups.
After 15 weeks, we discovered that LGG significantly reduced AS by lowering oxidative stress and inflammation, likely through activating specific pathways.
Additionally, LGG improved the gut microbiota, aligning it more closely with healthier control mice, which may enhance its heart protection benefits further.
After 15 weeks, we discovered that LGG significantly reduced AS by lowering oxidative stress and inflammation, likely through activating specific pathways.
Additionally, LGG improved the gut microbiota, aligning it more closely with healthier control mice, which may enhance its heart protection benefits further.
Read More
9
We investigated how bear bile powder (BBP) works within Shexiang Tongxin dropping pills (STDP) to treat acute myocardial infarction (AMI) in rats. Using various advanced techniques, we found that combining BBP with other components significantly reduced heart damage and improved gut health.
The treatment not only changed gene expression but also helped increase beneficial Lactobacillus bacteria. Overall, our findings highlight BBP's potential in enhancing cardiovascular therapy, although its effects alone were not as remarkable.
The treatment not only changed gene expression but also helped increase beneficial Lactobacillus bacteria. Overall, our findings highlight BBP's potential in enhancing cardiovascular therapy, although its effects alone were not as remarkable.
Read More
9
We looked into how the gut microbiome influences atrial fibrillation (AF) caused by the cancer drug ibrutinib. By examining various biological techniques, we discovered that the administration of ibrutinib increases the risk of AF in rats, particularly by decreasing levels of Lactobacillus gasseri.
However, we found that supplementing with L. gasseri or its metabolite butyrate can effectively prevent this condition. This suggests that modifying the gut microbiota could be a valuable strategy in managing drug-induced AF.
However, we found that supplementing with L. gasseri or its metabolite butyrate can effectively prevent this condition. This suggests that modifying the gut microbiota could be a valuable strategy in managing drug-induced AF.
Read More
9
We focused on the potential benefits of Lactobacillus supplementation in helping mitigate damage from ischemic stroke. Our study involved testing two specific strains, G89 and G133, in mice with induced strokes.
Notably, we observed that both strains helped reduce brain injury and improve recovery. They maintained gut barrier integrity and lowered inflammation. These findings suggest that probiotics could play a significant role in stroke treatment by influencing gut-brain-spleen communication.
Notably, we observed that both strains helped reduce brain injury and improve recovery. They maintained gut barrier integrity and lowered inflammation. These findings suggest that probiotics could play a significant role in stroke treatment by influencing gut-brain-spleen communication.
Read More
User Reviews
USERS' SCORE
Good
Based on 13 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Long-lasting relief
15 people found this helpful
Thrush winner! I read in one of the books in the "Elements" series of the "Dynasty" project about the bacterium Lactobacillus rhamnosus, which helps women manage gynecological diseases. After oncology and surgery, my microflora was disturbed, causing discomfort and thrush. I found "Fem Dophilus" on IHerb, which contains Lactobacillus rhamnosus and Lactobacillus reuteri. I took two courses with a month's break, and within two weeks I noticed improvement. Several years later, none of my problems have returned, and I recommended it to friends and family, who have all benefited.
Read More
9
Candida-free
4 people found this helpful
Very good! I've repurchased many times! It has an absolute effect on Candida! I face fewer body issues, and I'm now free from the disease. I take three capsules of Jarrow Formulas Fem Dophilus each night. With 60 vegetarian capsules and an additional California Gold Nutrition LactoBif Probiotic, I experience no discomfort. I've made multiple purchases from Hong Kong—if you find my comment useful, please give me a like. Thanks!
Read More
9
Life-changing product
This nutrient has become an essential part of my health routine! A friend recommended it years ago after she suffered from female issues like cystitis, which caused me considerable trouble at times. I have had to visit the emergency room early due to cystitis, but I was amazed at how quickly my symptoms improved with Jarrow Pamdophilus and cranberry supplements. The small pill size makes it easy to swallow and carry when travelling. I’ve also noticed benefits to my digestive health due to the lactic acid bacteria—very effective!
Read More
9
Healthy pregnancies
1 people found this helpful
Ladies, this is a must-have product for women! It combats issues "down there" effortlessly and has been instrumental in helping me stay healthy through three pregnancies when candida and other infections were a concern. This is the only women's probiotic brand I've used and seen real results with. Perhaps it offers better absorption? In any case, I wouldn't recommend any other brand.
Read More
7.5
Improved vaginitis
1 people found this helpful
I had a female-related disease, and after finding out about this product, I have been taking it for about 2 years. The changes before and after use have been significant; vaginitis has noticeably improved. It seems to be more effective after over 6 months of use. The small capsules are easy to take and store since they do not require refrigeration. I highly recommend it for anyone seeking exclusive lactic acid bacteria for female diseases.
Read More
Frequently Asked Questions
7.5
Improved vaginitis
1 people found this helpful
I had a female-related disease, and after finding out about this product, I have been taking it for about 2 years. The changes before and after use have been significant; vaginitis has noticeably improved. It seems to be more effective after over 6 months of use. The small capsules are easy to take and store since they do not require refrigeration. I highly recommend it for anyone seeking exclusive lactic acid bacteria for female diseases.
6
Slight improvement
I began taking it due to women's health concerns. While I noticed only minor changes, there is some improvement.
9
Long-lasting relief
15 people found this helpful
Thrush winner! I read in one of the books in the "Elements" series of the "Dynasty" project about the bacterium Lactobacillus rhamnosus, which helps women manage gynecological diseases. After oncology and surgery, my microflora was disturbed, causing discomfort and thrush. I found "Fem Dophilus" on IHerb, which contains Lactobacillus rhamnosus and Lactobacillus reuteri. I took two courses with a month's break, and within two weeks I noticed improvement. Several years later, none of my problems have returned, and I recommended it to friends and family, who have all benefited.
9
Life-changing product
This nutrient has become an essential part of my health routine! A friend recommended it years ago after she suffered from female issues like cystitis, which caused me considerable trouble at times. I have had to visit the emergency room early due to cystitis, but I was amazed at how quickly my symptoms improved with Jarrow Pamdophilus and cranberry supplements. The small pill size makes it easy to swallow and carry when travelling. I’ve also noticed benefits to my digestive health due to the lactic acid bacteria—very effective!
7.5
Alleviated symptoms
I think it’s a nutritional supplement for women. An acquaintance recommended it, and since using it, I’ve definitely noticed an improvement in alleviating female diseases like vaginitis. I am now on my third purchase. The price is on the higher side, but the benefits are worth it.
9
Candida-free
4 people found this helpful
Very good! I've repurchased many times! It has an absolute effect on Candida! I face fewer body issues, and I'm now free from the disease. I take three capsules of Jarrow Formulas Fem Dophilus each night. With 60 vegetarian capsules and an additional California Gold Nutrition LactoBif Probiotic, I experience no discomfort. I've made multiple purchases from Hong Kong—if you find my comment useful, please give me a like. Thanks!
9
Lactobacillus reduces atherosclerosis risk
We aimed to explore whether Lactobacillus rhamnosus GG (LGG) could help combat atherosclerosis (AS) in mice. In a controlled study, we administered LGG to ApoE mice and compared their outcomes to control groups.
After 15 weeks, we discovered that LGG significantly reduced AS by lowering oxidative stress and inflammation, likely through activating specific pathways.
Additionally, LGG improved the gut microbiota, aligning it more closely with healthier control mice, which may enhance its heart protection benefits further.
After 15 weeks, we discovered that LGG significantly reduced AS by lowering oxidative stress and inflammation, likely through activating specific pathways.
Additionally, LGG improved the gut microbiota, aligning it more closely with healthier control mice, which may enhance its heart protection benefits further.
8
We examined the role of Lactobacillus plantarum CCFM639 in managing high blood pressure. The study showcased that this specific strain can actually reduce blood pressure in people newly diagnosed with pre-hypertension or stage 1 hypertension.
Interestingly, we found that it might work by inhibiting the growth of another gut bacterium, Streptomyces aureofaciens Tü117, which is linked to vasodilation issues and high blood pressure. While the results are promising, they represent an exploratory look into how gut health could influence cardiovascular conditions.
Interestingly, we found that it might work by inhibiting the growth of another gut bacterium, Streptomyces aureofaciens Tü117, which is linked to vasodilation issues and high blood pressure. While the results are promising, they represent an exploratory look into how gut health could influence cardiovascular conditions.
8
Probiotics may help heart health
We investigated the role of probiotics in heart protection following a simulated heart attack in rats. Over 28 days, rats received daily doses of three probiotic strains, including Lactobacillus reuteri, before being induced with heart injury.
The results showed that these probiotics helped reduce the size of heart damage, lower inflammation, and decrease tissue scarring. However, while there were positive effects, more research is necessary to fully understand probiotics' potential benefits for heart health.
The results showed that these probiotics helped reduce the size of heart damage, lower inflammation, and decrease tissue scarring. However, while there were positive effects, more research is necessary to fully understand probiotics' potential benefits for heart health.
8
We investigated how Aucubin, a natural compound from Eucommia ulmoides, impacts atherosclerosis (AS) by influencing gut microbiota. Through detailed studies in ApoE mice and fecal microbiota transplants, we found that Aucubin reduced dyslipidemia and endothelial dysfunction in a dose-dependent manner.
Significantly, we noted an increase in Lactobacillus and its metabolite, indole-3-acrylic acid (IAA), which played a vital role in easing AS. While the findings highlight Aucubin’s promising anti-atherosclerotic effects, it remains essential to explore further implications for cardiovascular health.
Significantly, we noted an increase in Lactobacillus and its metabolite, indole-3-acrylic acid (IAA), which played a vital role in easing AS. While the findings highlight Aucubin’s promising anti-atherosclerotic effects, it remains essential to explore further implications for cardiovascular health.
References
- Zhang S, Xu L, Zhu C, Li J, Fu Y, et al. 166, Derived from Yak Yogurt from Tibetan Areas of Sichuan, Improves High-Fat-Diet-Induced Hyperlipidemia by Modulating Gut Microbiota and Liver- and Gut-Related Pathways. Foods. 2025;14. doi:10.3390/foods14050867
- Jena PK, Wakita D, Gomez AC, Carvalho TT, Atici AE, et al. Intestinal Microbiota Contributes to the Development of Cardiovascular Inflammation and Vasculitis in Mice. Circ Res. 2025;136:e53. doi:10.1161/CIRCRESAHA.124.325079
- Huang L, Huang L, Wang L, Wang Y, Xie W, et al. Nonsurgical periodontal treatment improved the abnormal trimethylamine n-oxide metabolism in Apoe mice with periodontitis. Biochim Biophys Acta Mol Basis Dis. 2025;1871:167752. doi:10.1016/j.bbadis.2025.167752
- Liu Y, Bai Z, Yan R, Ma J, Wang L, et al. Lactobacillus rhamnosus GG ameliorates atherosclerosis via suppression of oxidative stress and inflammation by reshaping the gut microbiota. Biochem Biophys Res Commun. 2025;751:151417. doi:10.1016/j.bbrc.2025.151417
- Zhou T, Wang Z, Lv X, Guo M, Zhang N, et al. Targeting gut S. aureofaciens Tü117 serves as a new potential therapeutic intervention for the prevention and treatment of hypertension. Cell Metab. 2025;37:496. doi:10.1016/j.cmet.2025.01.004
- Luo Y, Zhang F, Zhu L, Ye J, Pan HY, et al. Efficacy and compatibility mechanism of bear bile powder in Shexiang Tongxin dropping pills for acute myocardial infarction treatment. Chin Med. 2025;20:14. doi:10.1186/s13020-025-01060-x
- Shi L, Duan Y, Fang N, Zhang N, Yan S, et al. Lactobacillus gasseri prevents ibrutinib-associated atrial fibrillation through butyrate. Europace. 2025;27. doi:10.1093/europace/euaf018
- Ma C, Xu C, Zheng M, Zhang S, Liu Q, et al. Utilizing Lactic Acid Bacteria to Improve Hyperlipidemia: A Comprehensive Analysis from Gut Microbiota to Metabolic Pathways. Foods. 2024;13. doi:10.3390/foods13244058
- Wang R, Chen RL, Wu C, Zhang XC, Wu WY, et al. The gut microbiotas with metabolites regulate the protective role of miR-30a-5p in myocardial infarction. J Adv Res. 2024. doi:10.1016/j.jare.2024.10.017
- Wang YH, Liao JM, Jan MS, Wang M, Su HH, et al. Prophylactic use of probiotics as an adjunctive treatment for ischemic stroke via the gut-spleen-brain axis. Brain Behav Immun. 2025;123:784. doi:10.1016/j.bbi.2024.10.026
- Bonab SF, Tahmasebi S, Ghafouri-Fard S, Eslami S. Preventive impact of probiotic supplements on heart injury and inflammatory indices in a rat model of myocardial infarction: histopathological and gene expression evaluation. APMIS. 2025;133:e13479. doi:10.1111/apm.13479
- Luo Z, Yang L, Zhu T, Fan F, Wang X, et al. Aucubin ameliorates atherosclerosis by modulating tryptophan metabolism and inhibiting endothelial-mesenchymal transitions via gut microbiota regulation. Phytomedicine. 2024;135:156122. doi:10.1016/j.phymed.2024.156122
