Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.6
USERS' SCORE
Good
Based on 7 Reviews
8.1
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Turmeric ExtractCurcuma longa (Rhizome)(95% [475 mg] Total Curcuminoids)
500 mg
†
Top Medical Research Studies
9
Curcumin shows promise for anxiety
We explored the potential of curcumin, a natural compound found in turmeric, as a treatment for anxiety. Through a thorough analysis of eight randomized controlled trials that included 567 participants, we aimed to determine whether curcumin could effectively alleviate anxiety symptoms.
The results were promising. The analysis indicated a significant improvement in anxiety symptoms among those who took curcumin, with a standardized mean difference of -1.56. This suggests that curcumin may lead to a noticeable reduction in anxiety levels. However, it’s important to note that the studies included were limited in number, and the variety in their designs contributed to considerable variation in outcomes.
While we found indications that curcumin may offer benefits for individuals dealing with anxiety, we also recognize the need for further high-quality research to solidify these findings. Until more comprehensive studies are conducted, it's crucial to approach curcumin as a potential supplementary treatment, rather than a standalone solution for anxiety disorders.
The results were promising. The analysis indicated a significant improvement in anxiety symptoms among those who took curcumin, with a standardized mean difference of -1.56. This suggests that curcumin may lead to a noticeable reduction in anxiety levels. However, it’s important to note that the studies included were limited in number, and the variety in their designs contributed to considerable variation in outcomes.
While we found indications that curcumin may offer benefits for individuals dealing with anxiety, we also recognize the need for further high-quality research to solidify these findings. Until more comprehensive studies are conducted, it's crucial to approach curcumin as a potential supplementary treatment, rather than a standalone solution for anxiety disorders.
Read More
8
Curcumin shows promise for anxiety
We aimed to understand how curcumin, a compound derived from turmeric, impacts anxiety and depression in animals with a sustained infection. Our experimentation involved five groups of mice, including a control group, a model group subjected to long-term infection, and three groups treated with different dosages of curcumin.
Over a four-week period of infection, we then administered curcumin and monitored the mice for changes in behavior over two weeks. The results were enlightening! We observed that mice with chronic infections exhibited notable symptoms of anxiety and depression. However, those treated with curcumin showcased significant improvements in these behaviors.
Our findings suggest that curcumin may alleviate anxiety symptoms by influencing oxidative stress and inflammatory responses in the brain. This means curcumin could potentially be beneficial for individuals struggling with anxiety triggered by long-term infections. Overall, curcumin appears to be a promising natural option for tackling anxiety and depressive disorders linked to chronic infections.
Over a four-week period of infection, we then administered curcumin and monitored the mice for changes in behavior over two weeks. The results were enlightening! We observed that mice with chronic infections exhibited notable symptoms of anxiety and depression. However, those treated with curcumin showcased significant improvements in these behaviors.
Our findings suggest that curcumin may alleviate anxiety symptoms by influencing oxidative stress and inflammatory responses in the brain. This means curcumin could potentially be beneficial for individuals struggling with anxiety triggered by long-term infections. Overall, curcumin appears to be a promising natural option for tackling anxiety and depressive disorders linked to chronic infections.
Read More
8
Curcumin shows potential for anxiety relief
We evaluated whether curcumin, a compound found in turmeric, can help reduce anxiety and improve immune system responses. In this study, 81 individuals were divided into two groups: a control group without anxiety and a group experiencing moderate anxiety. The anxious participants took curcumin supplements for 15 days, receiving 1800 mg per day.
Our findings showed that those with anxiety had elevated levels of certain inflammatory markers and cortisol, a stress hormone. After curcumin treatment, the levels of these markers, particularly MCP-1 and sCD14, decreased significantly. This was promising, as it suggests that curcumin not only helps lower anxiety symptoms but also reduces inflammation and oxidative stress in the body.
Overall, we observed that curcumin may have protective effects against anxiety by balancing various bodily responses. However, it's important to note that while the results are encouraging, more extensive studies are needed to fully understand how curcumin impacts anxiety and inflammation.
Our findings showed that those with anxiety had elevated levels of certain inflammatory markers and cortisol, a stress hormone. After curcumin treatment, the levels of these markers, particularly MCP-1 and sCD14, decreased significantly. This was promising, as it suggests that curcumin not only helps lower anxiety symptoms but also reduces inflammation and oxidative stress in the body.
Overall, we observed that curcumin may have protective effects against anxiety by balancing various bodily responses. However, it's important to note that while the results are encouraging, more extensive studies are needed to fully understand how curcumin impacts anxiety and inflammation.
Read More
Most Useful Reviews
9
Reduces anxiety effectively
27 people found this helpful
If you suffer from inflammation or pain, this supplement is essential. Curcumin, shown to be as effective as ibuprofen, is a key addition for my joint pain and headaches. It may also alleviate anxiety if linked to inflammation. I double my dose when feeling unwell, and it noticeably speeds up recovery from infections.
Read More
7.5
Improves anxiety symptoms
417 people found this helpful
Curcumin is a remarkable supplement for those reluctant to take multiple additives. Research indicates its anti-cancer, anti-inflammatory and antioxidant properties, along with benefits for osteoarthritis and rheumatoid arthritis. I noticed improved mood and decreased anxiety while taking it, especially when combined with phospholipids and piperine for better absorption. However, ordinary turmeric lacks the required bioavailability.
Read More
7.5
Alleviates anxiety issues
1 people found this helpful
Curcumin is a powerful antioxidant and known for its anti-inflammatory effects. It has been scientifically validated to support those with rheumatoid arthritis and offers mood-lifting benefits, helping with stress and anxiety. Regular use can alleviate various health issues.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.6
- All Researches
9
Curcumin shows promise for anxiety
We explored the potential of curcumin, a natural compound found in turmeric, as a treatment for anxiety. Through a thorough analysis of eight randomized controlled trials that included 567 participants, we aimed to determine whether curcumin could effectively alleviate anxiety symptoms.
The results were promising. The analysis indicated a significant improvement in anxiety symptoms among those who took curcumin, with a standardized mean difference of -1.56. This suggests that curcumin may lead to a noticeable reduction in anxiety levels. However, it’s important to note that the studies included were limited in number, and the variety in their designs contributed to considerable variation in outcomes.
While we found indications that curcumin may offer benefits for individuals dealing with anxiety, we also recognize the need for further high-quality research to solidify these findings. Until more comprehensive studies are conducted, it's crucial to approach curcumin as a potential supplementary treatment, rather than a standalone solution for anxiety disorders.
The results were promising. The analysis indicated a significant improvement in anxiety symptoms among those who took curcumin, with a standardized mean difference of -1.56. This suggests that curcumin may lead to a noticeable reduction in anxiety levels. However, it’s important to note that the studies included were limited in number, and the variety in their designs contributed to considerable variation in outcomes.
While we found indications that curcumin may offer benefits for individuals dealing with anxiety, we also recognize the need for further high-quality research to solidify these findings. Until more comprehensive studies are conducted, it's crucial to approach curcumin as a potential supplementary treatment, rather than a standalone solution for anxiety disorders.
Read More
8
Curcumin shows potential for anxiety relief
We evaluated whether curcumin, a compound found in turmeric, can help reduce anxiety and improve immune system responses. In this study, 81 individuals were divided into two groups: a control group without anxiety and a group experiencing moderate anxiety. The anxious participants took curcumin supplements for 15 days, receiving 1800 mg per day.
Our findings showed that those with anxiety had elevated levels of certain inflammatory markers and cortisol, a stress hormone. After curcumin treatment, the levels of these markers, particularly MCP-1 and sCD14, decreased significantly. This was promising, as it suggests that curcumin not only helps lower anxiety symptoms but also reduces inflammation and oxidative stress in the body.
Overall, we observed that curcumin may have protective effects against anxiety by balancing various bodily responses. However, it's important to note that while the results are encouraging, more extensive studies are needed to fully understand how curcumin impacts anxiety and inflammation.
Our findings showed that those with anxiety had elevated levels of certain inflammatory markers and cortisol, a stress hormone. After curcumin treatment, the levels of these markers, particularly MCP-1 and sCD14, decreased significantly. This was promising, as it suggests that curcumin not only helps lower anxiety symptoms but also reduces inflammation and oxidative stress in the body.
Overall, we observed that curcumin may have protective effects against anxiety by balancing various bodily responses. However, it's important to note that while the results are encouraging, more extensive studies are needed to fully understand how curcumin impacts anxiety and inflammation.
Read More
8
We examined the effects of curcumin, a natural compound derived from turmeric, on anxiety-related behaviors in a mouse model of tuberous sclerosis complex (TSC). This study specifically focused on how curcumin might mitigate anxiety and improve social behaviors.
Our findings indicated that the abnormal social behaviors observed in TSC mice were alleviated with dietary curcumin treatment. By employing advanced imaging techniques, we assessed changes in brain connectivity and discovered that curcumin also improved indicators of brain structure, suggesting a beneficial effect on neural pathways associated with anxiety and social interaction.
Additionally, we noted changes in gut microbiota composition, revealing a relationship between gut health and brain function. Specifically, particular types of bacteria were significantly linked to improvements in brain connectivity metrics after curcumin treatment. Overall, we found promising results that highlight turmeric’s potential as a supportive therapy for anxiety, particularly in conditions like TSC.
Our findings indicated that the abnormal social behaviors observed in TSC mice were alleviated with dietary curcumin treatment. By employing advanced imaging techniques, we assessed changes in brain connectivity and discovered that curcumin also improved indicators of brain structure, suggesting a beneficial effect on neural pathways associated with anxiety and social interaction.
Additionally, we noted changes in gut microbiota composition, revealing a relationship between gut health and brain function. Specifically, particular types of bacteria were significantly linked to improvements in brain connectivity metrics after curcumin treatment. Overall, we found promising results that highlight turmeric’s potential as a supportive therapy for anxiety, particularly in conditions like TSC.
Read More
8
Curcumin shows promise for anxiety
We aimed to understand how curcumin, a compound derived from turmeric, impacts anxiety and depression in animals with a sustained infection. Our experimentation involved five groups of mice, including a control group, a model group subjected to long-term infection, and three groups treated with different dosages of curcumin.
Over a four-week period of infection, we then administered curcumin and monitored the mice for changes in behavior over two weeks. The results were enlightening! We observed that mice with chronic infections exhibited notable symptoms of anxiety and depression. However, those treated with curcumin showcased significant improvements in these behaviors.
Our findings suggest that curcumin may alleviate anxiety symptoms by influencing oxidative stress and inflammatory responses in the brain. This means curcumin could potentially be beneficial for individuals struggling with anxiety triggered by long-term infections. Overall, curcumin appears to be a promising natural option for tackling anxiety and depressive disorders linked to chronic infections.
Over a four-week period of infection, we then administered curcumin and monitored the mice for changes in behavior over two weeks. The results were enlightening! We observed that mice with chronic infections exhibited notable symptoms of anxiety and depression. However, those treated with curcumin showcased significant improvements in these behaviors.
Our findings suggest that curcumin may alleviate anxiety symptoms by influencing oxidative stress and inflammatory responses in the brain. This means curcumin could potentially be beneficial for individuals struggling with anxiety triggered by long-term infections. Overall, curcumin appears to be a promising natural option for tackling anxiety and depressive disorders linked to chronic infections.
Read More
8
We focused on understanding how curcumin, a compound found in turmeric, affects anxiety and neurotoxicity caused by doxorubicin (DOX). In our study, we carefully divided rats into three groups: a control group, a DOX group, and a DOX group that received curcumin.
After three weeks of treatment, we conducted several behavior tests to evaluate anxiety- and depression-like behaviors among the rats. Remarkably, we discovered that curcumin could effectively reverse the depressive-like symptoms associated with DOX treatment.
The results showed that DOX treatment heightened oxidative stress and activated autophagy, contributing to anxiety. However, curcumin administration significantly reduced these effects. Importantly, this research revealed that the Keap1-Nrf2-ARE signaling pathway played a key role in regulating the oxidative stress linked to DOX-induced neurotoxicity.
Overall, our findings suggest that curcumin could be a valuable ally in mitigating anxiety symptoms influenced by oxidative stress and neurotoxicity, potentially offering a therapeutic approach for individuals undergoing treatment with doxorubicin.
After three weeks of treatment, we conducted several behavior tests to evaluate anxiety- and depression-like behaviors among the rats. Remarkably, we discovered that curcumin could effectively reverse the depressive-like symptoms associated with DOX treatment.
The results showed that DOX treatment heightened oxidative stress and activated autophagy, contributing to anxiety. However, curcumin administration significantly reduced these effects. Importantly, this research revealed that the Keap1-Nrf2-ARE signaling pathway played a key role in regulating the oxidative stress linked to DOX-induced neurotoxicity.
Overall, our findings suggest that curcumin could be a valuable ally in mitigating anxiety symptoms influenced by oxidative stress and neurotoxicity, potentially offering a therapeutic approach for individuals undergoing treatment with doxorubicin.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reduces anxiety effectively
27 people found this helpful
If you suffer from inflammation or pain, this supplement is essential. Curcumin, shown to be as effective as ibuprofen, is a key addition for my joint pain and headaches. It may also alleviate anxiety if linked to inflammation. I double my dose when feeling unwell, and it noticeably speeds up recovery from infections.
Read More
7.5
Improves anxiety symptoms
417 people found this helpful
Curcumin is a remarkable supplement for those reluctant to take multiple additives. Research indicates its anti-cancer, anti-inflammatory and antioxidant properties, along with benefits for osteoarthritis and rheumatoid arthritis. I noticed improved mood and decreased anxiety while taking it, especially when combined with phospholipids and piperine for better absorption. However, ordinary turmeric lacks the required bioavailability.
Read More
7.5
Alleviates anxiety issues
1 people found this helpful
Curcumin is a powerful antioxidant and known for its anti-inflammatory effects. It has been scientifically validated to support those with rheumatoid arthritis and offers mood-lifting benefits, helping with stress and anxiety. Regular use can alleviate various health issues.
Read More
9
Mitigates anxiety effects
Curcumin offers strong anti-inflammatory properties that protect brain health. It effectively reduces anxiety and promotes neuroplasticity. This reinforces its role in supporting mental health and cognitive function.
Read More
7.5
Supports anxiety relief
Research indicates that curcumin may aid in managing oxidative and inflammatory conditions, including anxiety and arthritis. Additionally, it can help with recovery from exercise-induced soreness, benefiting overall performance for active individuals.
Read More
Frequently Asked Questions
7.5
Improves anxiety symptoms
417 people found this helpful
Curcumin is a remarkable supplement for those reluctant to take multiple additives. Research indicates its anti-cancer, anti-inflammatory and antioxidant properties, along with benefits for osteoarthritis and rheumatoid arthritis. I noticed improved mood and decreased anxiety while taking it, especially when combined with phospholipids and piperine for better absorption. However, ordinary turmeric lacks the required bioavailability.
9
Mitigates anxiety effects
Curcumin offers strong anti-inflammatory properties that protect brain health. It effectively reduces anxiety and promotes neuroplasticity. This reinforces its role in supporting mental health and cognitive function.
9
Reduces anxiety effectively
27 people found this helpful
If you suffer from inflammation or pain, this supplement is essential. Curcumin, shown to be as effective as ibuprofen, is a key addition for my joint pain and headaches. It may also alleviate anxiety if linked to inflammation. I double my dose when feeling unwell, and it noticeably speeds up recovery from infections.
7.5
Enhances mood stability
This supplement has positively influenced my mood, reducing the likelihood of anxiety and depression. It's particularly beneficial for anyone dealing with mood disorders, helping to maintain mental health through diet.
6
Eases stress levels
Curcumin assists with numerous health issues including skin diseases and anxiety. It enhances mood, reduces stress and fatigue, and improves cognitive functions such as intelligence and attention. This supplement has significant benefits for mental well-being.
7.5
Alleviates anxiety issues
1 people found this helpful
Curcumin is a powerful antioxidant and known for its anti-inflammatory effects. It has been scientifically validated to support those with rheumatoid arthritis and offers mood-lifting benefits, helping with stress and anxiety. Regular use can alleviate various health issues.
7.5
Supports anxiety relief
Research indicates that curcumin may aid in managing oxidative and inflammatory conditions, including anxiety and arthritis. Additionally, it can help with recovery from exercise-induced soreness, benefiting overall performance for active individuals.
9
Curcumin shows promise for anxiety
We explored the potential of curcumin, a natural compound found in turmeric, as a treatment for anxiety. Through a thorough analysis of eight randomized controlled trials that included 567 participants, we aimed to determine whether curcumin could effectively alleviate anxiety symptoms.
The results were promising. The analysis indicated a significant improvement in anxiety symptoms among those who took curcumin, with a standardized mean difference of -1.56. This suggests that curcumin may lead to a noticeable reduction in anxiety levels. However, it’s important to note that the studies included were limited in number, and the variety in their designs contributed to considerable variation in outcomes.
While we found indications that curcumin may offer benefits for individuals dealing with anxiety, we also recognize the need for further high-quality research to solidify these findings. Until more comprehensive studies are conducted, it's crucial to approach curcumin as a potential supplementary treatment, rather than a standalone solution for anxiety disorders.
The results were promising. The analysis indicated a significant improvement in anxiety symptoms among those who took curcumin, with a standardized mean difference of -1.56. This suggests that curcumin may lead to a noticeable reduction in anxiety levels. However, it’s important to note that the studies included were limited in number, and the variety in their designs contributed to considerable variation in outcomes.
While we found indications that curcumin may offer benefits for individuals dealing with anxiety, we also recognize the need for further high-quality research to solidify these findings. Until more comprehensive studies are conducted, it's crucial to approach curcumin as a potential supplementary treatment, rather than a standalone solution for anxiety disorders.
8
Curcumin shows potential for anxiety relief
We evaluated whether curcumin, a compound found in turmeric, can help reduce anxiety and improve immune system responses. In this study, 81 individuals were divided into two groups: a control group without anxiety and a group experiencing moderate anxiety. The anxious participants took curcumin supplements for 15 days, receiving 1800 mg per day.
Our findings showed that those with anxiety had elevated levels of certain inflammatory markers and cortisol, a stress hormone. After curcumin treatment, the levels of these markers, particularly MCP-1 and sCD14, decreased significantly. This was promising, as it suggests that curcumin not only helps lower anxiety symptoms but also reduces inflammation and oxidative stress in the body.
Overall, we observed that curcumin may have protective effects against anxiety by balancing various bodily responses. However, it's important to note that while the results are encouraging, more extensive studies are needed to fully understand how curcumin impacts anxiety and inflammation.
Our findings showed that those with anxiety had elevated levels of certain inflammatory markers and cortisol, a stress hormone. After curcumin treatment, the levels of these markers, particularly MCP-1 and sCD14, decreased significantly. This was promising, as it suggests that curcumin not only helps lower anxiety symptoms but also reduces inflammation and oxidative stress in the body.
Overall, we observed that curcumin may have protective effects against anxiety by balancing various bodily responses. However, it's important to note that while the results are encouraging, more extensive studies are needed to fully understand how curcumin impacts anxiety and inflammation.
7
We investigated how curcumin, a component of turmeric, affects anxiety-like behaviors in rats. Our research focused on rat offspring exposed to an amorphous form of curcumin from their early development, and we observed some exciting outcomes. These young rats displayed reduced anxiety, improved fear extinction learning, and enhanced synaptic plasticity in a specific area of the brain known as the hippocampus.
To understand what was happening at a molecular level, we looked at the genes within the brain's neurogenic niche that showed changes in their methylation status—essentially how these genes are turned on or off. After thorough analysis, we discovered that certain genes were hypermethylated and downregulated, including Gpr150 and Pcdh8, while others like Ppm1j and Opn3 were hypomethylated and upregulated. This balance in gene expression suggests that curcumin might play a vital role in brain function and emotional regulation.
Additionally, we observed changes in specific types of brain cells, such as a reduction in certain interneurons and an increase in others that are important for mood regulation. The changes indicated that curcumin could enhance synaptic connections, which is crucial for maintaining healthy brain functions. Overall, our findings suggest that curcumin exposure leads to significant changes in brain chemistry that may contribute to decreased anxiety and improved learning in these rats.
To understand what was happening at a molecular level, we looked at the genes within the brain's neurogenic niche that showed changes in their methylation status—essentially how these genes are turned on or off. After thorough analysis, we discovered that certain genes were hypermethylated and downregulated, including Gpr150 and Pcdh8, while others like Ppm1j and Opn3 were hypomethylated and upregulated. This balance in gene expression suggests that curcumin might play a vital role in brain function and emotional regulation.
Additionally, we observed changes in specific types of brain cells, such as a reduction in certain interneurons and an increase in others that are important for mood regulation. The changes indicated that curcumin could enhance synaptic connections, which is crucial for maintaining healthy brain functions. Overall, our findings suggest that curcumin exposure leads to significant changes in brain chemistry that may contribute to decreased anxiety and improved learning in these rats.
4
Curcumin's limited effect on anxiety
We conducted a randomized, double-blind clinical trial to explore the effects of curcumin, a compound found in turmeric, on anxiety levels in patients with severe major depressive disorder (MDD). A total of 45 participants received either sertraline along with curcumin or a placebo for eight weeks.
Throughout the study, we monitored changes in anxiety and depression using standardized surveys. Although we observed that both anxiety and depression scores decreased over the eight weeks, the results revealed no significant difference between the group that received curcumin and the placebo group.
Interestingly, while curcumin did not appear to enhance the effectiveness of sertraline for treating depression, the anxiety scores were slightly lower in the group taking curcumin. This suggests that curcumin might have a more positive effect on anxiety than on depression, but more research is necessary to confirm these findings.
Overall, while our study indicates that adding curcumin to standard depression treatment didn't show a significant benefit for depression or anxiety levels, there may still be a glimmer of hope for its potential impact on anxiety specifically.
Throughout the study, we monitored changes in anxiety and depression using standardized surveys. Although we observed that both anxiety and depression scores decreased over the eight weeks, the results revealed no significant difference between the group that received curcumin and the placebo group.
Interestingly, while curcumin did not appear to enhance the effectiveness of sertraline for treating depression, the anxiety scores were slightly lower in the group taking curcumin. This suggests that curcumin might have a more positive effect on anxiety than on depression, but more research is necessary to confirm these findings.
Overall, while our study indicates that adding curcumin to standard depression treatment didn't show a significant benefit for depression or anxiety levels, there may still be a glimmer of hope for its potential impact on anxiety specifically.
8
Curcumin shows promise for anxiety
We aimed to understand how curcumin, a compound derived from turmeric, impacts anxiety and depression in animals with a sustained infection. Our experimentation involved five groups of mice, including a control group, a model group subjected to long-term infection, and three groups treated with different dosages of curcumin.
Over a four-week period of infection, we then administered curcumin and monitored the mice for changes in behavior over two weeks. The results were enlightening! We observed that mice with chronic infections exhibited notable symptoms of anxiety and depression. However, those treated with curcumin showcased significant improvements in these behaviors.
Our findings suggest that curcumin may alleviate anxiety symptoms by influencing oxidative stress and inflammatory responses in the brain. This means curcumin could potentially be beneficial for individuals struggling with anxiety triggered by long-term infections. Overall, curcumin appears to be a promising natural option for tackling anxiety and depressive disorders linked to chronic infections.
Over a four-week period of infection, we then administered curcumin and monitored the mice for changes in behavior over two weeks. The results were enlightening! We observed that mice with chronic infections exhibited notable symptoms of anxiety and depression. However, those treated with curcumin showcased significant improvements in these behaviors.
Our findings suggest that curcumin may alleviate anxiety symptoms by influencing oxidative stress and inflammatory responses in the brain. This means curcumin could potentially be beneficial for individuals struggling with anxiety triggered by long-term infections. Overall, curcumin appears to be a promising natural option for tackling anxiety and depressive disorders linked to chronic infections.
References
- Merino JJ, Parmigiani-Cabaña JM, Parmigiani-Izquierdo JM, Fernández-García R, Cabaña-Muñoz ME. Decreased Systemic Monocyte Colony Protein-1 (MCP-1) Levels and Reduced sCD14 Levels in Curcumin-Treated Patients with Moderate Anxiety: A Pilot Study. Antioxidants (Basel). 2024;13. doi:10.3390/antiox13091052
- Fathi S, Agharloo S, Falahatzadeh M, Bahraminavid S, Homayooni A, et al. Effect of curcumin supplementation on symptoms of anxiety: A systematic review and meta-analysis of randomized controlled trials. Clin Nutr ESPEN. 2024;62:253. doi:10.1016/j.clnesp.2024.05.017
- Tang Q, Ojiro R, Ozawa S, Zou X, Nakahara J, et al. DNA methylation-altered genes in the rat hippocampal neurogenic niche after continuous exposure to amorphous curcumin. J Chem Neuroanat. 2024;137:102414. doi:10.1016/j.jchemneu.2024.102414
- Hsieh CC, Lo YC, Wang HH, Shen HY, Chen YY, et al. Amelioration of the brain structural connectivity is accompanied with changes of gut microbiota in a tuberous sclerosis complex mouse model. Transl Psychiatry. 2024;14:68. doi:10.1038/s41398-024-02752-y
- Talaei A, Noori R, Rezaei Ardani A, Mohammadpour AH, Azimipoor Z, et al. The Effect of Adding Curcumin to Sertraline in the Treatment of Severe Major Depressive Disorder: A Randomized, Double-Blind Clinical Trial. Clin Neuropharmacol. 2023. doi:10.1097/WNF.0000000000000553
- Moradi F, Dashti N, Farahvash A, Baghaei Naeini F, Zarebavani M. Curcumin ameliorates chronic infection-induced affective disorders through modulation of proinflammatory cytokines and oxidative stress. Iran J Basic Med Sci. 2023;26:461. doi:10.22038/IJBMS.2023.68487.14937
- Liao D, Shangguan D, Wu Y, Chen Y, Liu N, et al. Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways. Psychopharmacology (Berl). 2023;240:1179. doi:10.1007/s00213-023-06357-z
- Vastegani SM, Hajipour S, Sarkaki A, Basir Z, Farbood Y, et al. Curcumin Ameliorates Neurobehavioral Deficits in Ambient Dusty Particulate Matter-Exposure Rats: The Role of Oxidative Stress. Neurochem Res. 2023;48:1798. doi:10.1007/s11064-023-03877-0
- Faucher P, Dries A, Mousset PY, Leboyer M, Dore J, et al. Synergistic effects of GG, glutamine, and curcumin on chronic unpredictable mild stress-induced depression in a mouse model. Benef Microbes. 2022;13:253. doi:10.3920/BM2021.0188
- Moradi Vastegani S, Hajipour S, Sarkaki A, Basir Z, Parisa Navabi S, et al. Curcumin mitigates lipopolysaccharide-induced anxiety/depression-like behaviors, blood-brain barrier dysfunction and brain edema by decreasing cerebral oxidative stress in male rats. Neurosci Lett. 2022;782:136697. doi:10.1016/j.neulet.2022.136697
