Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.6
USERS' SCORE
Good
Based on 5 Reviews
8.6
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Turmeric ExtractCurcuma longa (Rhizome)(95% [475 mg] Total Curcuminoids)
500 mg
†
Top Medical Research Studies
8
We explored the potential of curcumin, a natural compound derived from turmeric, as a treatment for psoriasis. Known for its anti-inflammatory properties, curcumin has been used in traditional medicine for centuries and is now being recognized for its role in modern therapeutic approaches. Psoriasis, a chronic skin condition marked by red, scaly patches, can be challenging to manage, making the search for effective treatments crucial.
The study highlighted curcumin's ability to inhibit specific enzymes and proteins that contribute to the inflammation and proliferation of skin cells associated with psoriasis. Interestingly, curcumin is being formulated into nanogels—small, crosslinked hydrogels that enhance the delivery of the compound. This nanogel preparation not only boosts the solubility and stability of curcumin but also increases its bioavailability, meaning we may need lower doses to achieve the desired results.
Ultimately, we found that curcumin nanogels present a promising alternative to traditional psoriasis treatments. They offer a potential pathway to more effective and safer treatment options. However, it's essential to emphasize that more research is necessary to fully understand how well these curcumin nanogels work in humans before they become a standard part of psoriasis care.
The study highlighted curcumin's ability to inhibit specific enzymes and proteins that contribute to the inflammation and proliferation of skin cells associated with psoriasis. Interestingly, curcumin is being formulated into nanogels—small, crosslinked hydrogels that enhance the delivery of the compound. This nanogel preparation not only boosts the solubility and stability of curcumin but also increases its bioavailability, meaning we may need lower doses to achieve the desired results.
Ultimately, we found that curcumin nanogels present a promising alternative to traditional psoriasis treatments. They offer a potential pathway to more effective and safer treatment options. However, it's essential to emphasize that more research is necessary to fully understand how well these curcumin nanogels work in humans before they become a standard part of psoriasis care.
Read More
8
We identified 18 studies that investigated the use of turmeric, particularly its active ingredient curcumin, for treating several skin conditions, including psoriasis. These studies were all randomized controlled trials, which is the gold standard in clinical research.
Our focus was primarily on psoriasis, and we found that curcumin was assigned a grade of recommendation B. This suggests that there is moderate evidence supporting its effectiveness in helping to manage psoriasis symptoms. Furthermore, the studies consistently reported an excellent safety profile for curcumin, making it a viable option for many patients.
However, we also recognized the need for more extensive research to refine dosing and treatment parameters. Understanding the optimal use of curcumin could lead to even better outcomes for individuals living with psoriasis. Overall, the findings are encouraging, showing that turmeric has potential as a natural treatment for this common skin condition.
Our focus was primarily on psoriasis, and we found that curcumin was assigned a grade of recommendation B. This suggests that there is moderate evidence supporting its effectiveness in helping to manage psoriasis symptoms. Furthermore, the studies consistently reported an excellent safety profile for curcumin, making it a viable option for many patients.
However, we also recognized the need for more extensive research to refine dosing and treatment parameters. Understanding the optimal use of curcumin could lead to even better outcomes for individuals living with psoriasis. Overall, the findings are encouraging, showing that turmeric has potential as a natural treatment for this common skin condition.
Read More
9
We investigated the potential benefits of curcumin, a compound found in turmeric, for treating psoriasis using a well-structured study on mice. By administering curcumin daily at a dose of 100 mg/kg, we observed significant improvements in psoriasis-like symptoms, such as reduced skin lesions and lower scores on severity measures.
Our findings showed that curcumin effectively decreased pro-inflammatory substances like IL-6, IL-17A, and TNF-α while promoting the production of the anti-inflammatory IL-10. Importantly, this study also explored how curcumin affects gut health, revealing it positively influences specific gut bacteria linked to inflammation.
In summary, we found that curcumin can alleviate psoriasis symptoms by modulating inflammatory responses and possibly enhancing gut microbiota. This positions turmeric as a promising natural option for psoriasis management worth considering for future treatments.
Our findings showed that curcumin effectively decreased pro-inflammatory substances like IL-6, IL-17A, and TNF-α while promoting the production of the anti-inflammatory IL-10. Importantly, this study also explored how curcumin affects gut health, revealing it positively influences specific gut bacteria linked to inflammation.
In summary, we found that curcumin can alleviate psoriasis symptoms by modulating inflammatory responses and possibly enhancing gut microbiota. This positions turmeric as a promising natural option for psoriasis management worth considering for future treatments.
Read More
Most Useful Reviews
9
Milk Thistle clears psoriasis
481 people found this helpful
After struggling with tiredness and skin issues like psoriasis, I started taking Milk Thistle. I suspected my liver was affected due to years of pain medication. Within a month of use, my psoriasis cleared, and I’ve gained more energy. I've completely changed my diet by eliminating sugars, which has further improved my skin and overall health. I will keep taking it to maintain these benefits.
Read More
9
Good for psoriasis
Curcumin is essential in one’s diet for its antiseptic qualities and ability to relieve inflammation. It speeds up healing, manages arthritis, and effectively addresses psoriasis, eczema, and other skin conditions. It also enhances metabolism, detoxifies the body, and helps combat depression and chronic fatigue.
Read More
7.5
Effective for psoriasis
In the complex treatment of psoriasis, my doctor prescribed this dietary supplement. I followed the recommended scheme and did not experience any side effects. I have also read that it is beneficial to take during COVID or other viral infections.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.6
- All Researches
9
We investigated how Curcumin, a compound found in turmeric, may help manage psoriasis, a chronic inflammatory skin condition. Our research focused on the effects of Curcumin-based nanoparticles combined with alpha-linolenic acid (a type of omega-3 fatty acid) in an in vitro model. This model included macrophages and keratinocytes, allowing us to simulate the inflammatory responses typical of psoriasis.
In our experiments, we found that these nanoparticles significantly reduced the expression of key inflammatory proteins in macrophages and improved the health of keratinocytes. Specifically, we saw a notable decrease in the cytokines IL-23, IL-8, and IL-6, which are often elevated in psoriasis. In keratinocytes, the treatment decreased cell death and repressed markers of ferroptosis, a recently identified process involved in psoriasis.
These promising results suggest that Curcumin-based nanoparticles could serve as a new strategy in treating psoriasis. However, more research is needed to explore their effectiveness in real-world applications before they can be recommended as a topical treatment.
In our experiments, we found that these nanoparticles significantly reduced the expression of key inflammatory proteins in macrophages and improved the health of keratinocytes. Specifically, we saw a notable decrease in the cytokines IL-23, IL-8, and IL-6, which are often elevated in psoriasis. In keratinocytes, the treatment decreased cell death and repressed markers of ferroptosis, a recently identified process involved in psoriasis.
These promising results suggest that Curcumin-based nanoparticles could serve as a new strategy in treating psoriasis. However, more research is needed to explore their effectiveness in real-world applications before they can be recommended as a topical treatment.
Read More
9
We investigated how a specially formulated curcumin-based ionic liquid hydrogel, designed to deliver therapeutic compounds for psoriasis, affects skin health. The study employed a psoriasis model induced by imiquimod to observe the effects of the hydrogel on skin lesions in mice.
Our findings showed that the local application of this hydrogel could lead to significant improvements in skin conditions. We noted a marked reduction in inflammatory factors and key proteins associated with skin health, such as matrix metalloproteinase 8 and collagen-I.
Additionally, treatment with the hydrogel resulted in lower levels of certain proteins related to iron metabolism, indicating further benefits. The hydrogel also appeared to positively influence gut bacteria profiles in the affected mice, suggesting a broader impact on their overall health.
Overall, this curcumin-infused hydrogel emerges as a promising multifunctional option for addressing psoriasis, providing a nonirritating and effective transdermal treatment.
Our findings showed that the local application of this hydrogel could lead to significant improvements in skin conditions. We noted a marked reduction in inflammatory factors and key proteins associated with skin health, such as matrix metalloproteinase 8 and collagen-I.
Additionally, treatment with the hydrogel resulted in lower levels of certain proteins related to iron metabolism, indicating further benefits. The hydrogel also appeared to positively influence gut bacteria profiles in the affected mice, suggesting a broader impact on their overall health.
Overall, this curcumin-infused hydrogel emerges as a promising multifunctional option for addressing psoriasis, providing a nonirritating and effective transdermal treatment.
Read More
9
We explored the potential of curcumin, derived from turmeric, as a natural remedy for psoriasis and examined how combining it with tea tree oil can enhance its effectiveness. Psoriasis is a chronic skin condition that leads to distressing symptoms like inflamed, scaly patches on the skin, and the search for effective treatments is ongoing.
Our approach involved creating a bi-phasic emulgel combining curcumin and tea tree oil to deliver these natural compounds effectively. We discovered that our emulgel formulation had a higher drug content and better spreadability compared to a standard gel formulation.
The emulgel not only released more of its active ingredients but also demonstrated superior performance in healing psoriasis symptoms in biological testing. The results suggest that the synergy between curcumin and tea tree oil offers a promising new treatment avenue for those suffering from psoriasis, showcasing a natural alternative to conventional medications.
Our approach involved creating a bi-phasic emulgel combining curcumin and tea tree oil to deliver these natural compounds effectively. We discovered that our emulgel formulation had a higher drug content and better spreadability compared to a standard gel formulation.
The emulgel not only released more of its active ingredients but also demonstrated superior performance in healing psoriasis symptoms in biological testing. The results suggest that the synergy between curcumin and tea tree oil offers a promising new treatment avenue for those suffering from psoriasis, showcasing a natural alternative to conventional medications.
Read More
9
We investigated how curcumin—a compound found in turmeric—impacts psoriasis-like dermatitis in mice. Sixteen mice were divided into four groups to observe varying effects of curcumin compared to a control group. The mice in the model and curcumin groups received a topical treatment of 5% imiquimod daily for six days, a method used to induce skin lesions similar to psoriasis.
Throughout the study, we applied different dosages of curcumin orally while some mice received saline. Our findings showed that curcumin significantly alleviated the symptoms induced by imiquimod. We specifically measured proteins and genetic markers related to inflammation, like TNF-α and IL-6, and noted that curcumin effectively reduced their levels in the skin tissues.
Additionally, the study highlighted that curcumin interfered with the activation of the STAT3 signaling pathway, which is often implicated in psoriasis development. This suggests a pathway where curcumin could contribute to healing from psoriasis-like conditions. Overall, our results indicate that curcumin is not only beneficial but may serve as a therapeutic candidate due to its influence on crucial inflammatory markers involved in psoriasis.
Throughout the study, we applied different dosages of curcumin orally while some mice received saline. Our findings showed that curcumin significantly alleviated the symptoms induced by imiquimod. We specifically measured proteins and genetic markers related to inflammation, like TNF-α and IL-6, and noted that curcumin effectively reduced their levels in the skin tissues.
Additionally, the study highlighted that curcumin interfered with the activation of the STAT3 signaling pathway, which is often implicated in psoriasis development. This suggests a pathway where curcumin could contribute to healing from psoriasis-like conditions. Overall, our results indicate that curcumin is not only beneficial but may serve as a therapeutic candidate due to its influence on crucial inflammatory markers involved in psoriasis.
Read More
9
We investigated the potential benefits of curcumin, a compound found in turmeric, for treating psoriasis using a well-structured study on mice. By administering curcumin daily at a dose of 100 mg/kg, we observed significant improvements in psoriasis-like symptoms, such as reduced skin lesions and lower scores on severity measures.
Our findings showed that curcumin effectively decreased pro-inflammatory substances like IL-6, IL-17A, and TNF-α while promoting the production of the anti-inflammatory IL-10. Importantly, this study also explored how curcumin affects gut health, revealing it positively influences specific gut bacteria linked to inflammation.
In summary, we found that curcumin can alleviate psoriasis symptoms by modulating inflammatory responses and possibly enhancing gut microbiota. This positions turmeric as a promising natural option for psoriasis management worth considering for future treatments.
Our findings showed that curcumin effectively decreased pro-inflammatory substances like IL-6, IL-17A, and TNF-α while promoting the production of the anti-inflammatory IL-10. Importantly, this study also explored how curcumin affects gut health, revealing it positively influences specific gut bacteria linked to inflammation.
In summary, we found that curcumin can alleviate psoriasis symptoms by modulating inflammatory responses and possibly enhancing gut microbiota. This positions turmeric as a promising natural option for psoriasis management worth considering for future treatments.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Milk Thistle clears psoriasis
481 people found this helpful
After struggling with tiredness and skin issues like psoriasis, I started taking Milk Thistle. I suspected my liver was affected due to years of pain medication. Within a month of use, my psoriasis cleared, and I’ve gained more energy. I've completely changed my diet by eliminating sugars, which has further improved my skin and overall health. I will keep taking it to maintain these benefits.
Read More
9
Good for psoriasis
Curcumin is essential in one’s diet for its antiseptic qualities and ability to relieve inflammation. It speeds up healing, manages arthritis, and effectively addresses psoriasis, eczema, and other skin conditions. It also enhances metabolism, detoxifies the body, and helps combat depression and chronic fatigue.
Read More
7.5
Effective for psoriasis
In the complex treatment of psoriasis, my doctor prescribed this dietary supplement. I followed the recommended scheme and did not experience any side effects. I have also read that it is beneficial to take during COVID or other viral infections.
Read More
7.5
Helpful for psoriasis
Curcumin is a remarkable healer with antibacterial properties that alleviate pain and inflammation. It reduces the risk of diabetes and helps with liver issues, including fatty liver and hepatitis. Curcumin has proven effective in treating inflammatory skin conditions like acne and psoriasis while promoting metabolism and aiding weight management.
Read More
6
Helps treat psoriasis
1 people found this helpful
The benefits of curcumin include reducing chronic inflammation, which can lead to various health issues, including cardiovascular diseases. It is particularly effective for arthritis, as it alleviates joint swelling. I find that regular use of curcumin diminishes the risk of liver diseases and eases symptoms of conditions like hepatitis. Additionally, it may slow the progression or lessen the symptoms of psoriasis, among other ailments.
Read More
Frequently Asked Questions
7.5
Effective for psoriasis
In the complex treatment of psoriasis, my doctor prescribed this dietary supplement. I followed the recommended scheme and did not experience any side effects. I have also read that it is beneficial to take during COVID or other viral infections.
6
Helps treat psoriasis
1 people found this helpful
The benefits of curcumin include reducing chronic inflammation, which can lead to various health issues, including cardiovascular diseases. It is particularly effective for arthritis, as it alleviates joint swelling. I find that regular use of curcumin diminishes the risk of liver diseases and eases symptoms of conditions like hepatitis. Additionally, it may slow the progression or lessen the symptoms of psoriasis, among other ailments.
7.5
Helpful for psoriasis
Curcumin is a remarkable healer with antibacterial properties that alleviate pain and inflammation. It reduces the risk of diabetes and helps with liver issues, including fatty liver and hepatitis. Curcumin has proven effective in treating inflammatory skin conditions like acne and psoriasis while promoting metabolism and aiding weight management.
9
Good for psoriasis
Curcumin is essential in one’s diet for its antiseptic qualities and ability to relieve inflammation. It speeds up healing, manages arthritis, and effectively addresses psoriasis, eczema, and other skin conditions. It also enhances metabolism, detoxifies the body, and helps combat depression and chronic fatigue.
9
We investigated how Curcumin, a compound found in turmeric, may help manage psoriasis, a chronic inflammatory skin condition. Our research focused on the effects of Curcumin-based nanoparticles combined with alpha-linolenic acid (a type of omega-3 fatty acid) in an in vitro model. This model included macrophages and keratinocytes, allowing us to simulate the inflammatory responses typical of psoriasis.
In our experiments, we found that these nanoparticles significantly reduced the expression of key inflammatory proteins in macrophages and improved the health of keratinocytes. Specifically, we saw a notable decrease in the cytokines IL-23, IL-8, and IL-6, which are often elevated in psoriasis. In keratinocytes, the treatment decreased cell death and repressed markers of ferroptosis, a recently identified process involved in psoriasis.
These promising results suggest that Curcumin-based nanoparticles could serve as a new strategy in treating psoriasis. However, more research is needed to explore their effectiveness in real-world applications before they can be recommended as a topical treatment.
In our experiments, we found that these nanoparticles significantly reduced the expression of key inflammatory proteins in macrophages and improved the health of keratinocytes. Specifically, we saw a notable decrease in the cytokines IL-23, IL-8, and IL-6, which are often elevated in psoriasis. In keratinocytes, the treatment decreased cell death and repressed markers of ferroptosis, a recently identified process involved in psoriasis.
These promising results suggest that Curcumin-based nanoparticles could serve as a new strategy in treating psoriasis. However, more research is needed to explore their effectiveness in real-world applications before they can be recommended as a topical treatment.
8
We focused on enhancing the topical delivery of curcumin, a compound derived from turmeric, to treat psoriasis effectively. Our approach involved an oligopeptide hydrogel that incorporated curcumin-loaded nanoemulsions, designed to penetrate the skin better.
The treatment utilized cell-penetrating peptides to help the curcumin nanoemulsions reach deeper layers of the skin, overcoming the barrier posed by the outermost skin layer, known as the stratum corneum.
When we applied this innovative treatment to psoriatic mice, we observed that it remained effective on the skin for an extended period, leading to notable relief from psoriasis symptoms. This method demonstrated promise for improving the delivery and effectiveness of turmeric-based treatments, making it a potential game-changer for topical psoriasis therapies.
The treatment utilized cell-penetrating peptides to help the curcumin nanoemulsions reach deeper layers of the skin, overcoming the barrier posed by the outermost skin layer, known as the stratum corneum.
When we applied this innovative treatment to psoriatic mice, we observed that it remained effective on the skin for an extended period, leading to notable relief from psoriasis symptoms. This method demonstrated promise for improving the delivery and effectiveness of turmeric-based treatments, making it a potential game-changer for topical psoriasis therapies.
8
We identified 18 studies that investigated the use of turmeric, particularly its active ingredient curcumin, for treating several skin conditions, including psoriasis. These studies were all randomized controlled trials, which is the gold standard in clinical research.
Our focus was primarily on psoriasis, and we found that curcumin was assigned a grade of recommendation B. This suggests that there is moderate evidence supporting its effectiveness in helping to manage psoriasis symptoms. Furthermore, the studies consistently reported an excellent safety profile for curcumin, making it a viable option for many patients.
However, we also recognized the need for more extensive research to refine dosing and treatment parameters. Understanding the optimal use of curcumin could lead to even better outcomes for individuals living with psoriasis. Overall, the findings are encouraging, showing that turmeric has potential as a natural treatment for this common skin condition.
Our focus was primarily on psoriasis, and we found that curcumin was assigned a grade of recommendation B. This suggests that there is moderate evidence supporting its effectiveness in helping to manage psoriasis symptoms. Furthermore, the studies consistently reported an excellent safety profile for curcumin, making it a viable option for many patients.
However, we also recognized the need for more extensive research to refine dosing and treatment parameters. Understanding the optimal use of curcumin could lead to even better outcomes for individuals living with psoriasis. Overall, the findings are encouraging, showing that turmeric has potential as a natural treatment for this common skin condition.
References
- Serini S, Trombino S, Cassano R, Marino M, Calviello G. Anti-Inflammatory Effects of Curcumin-Based Nanoparticles Containing α-Linolenic Acid in a Model of Psoriasis In Vitro. Nutrients. 2025;17. doi:10.3390/nu17040692
- Chen K, Yang H, Xu G, Hu Y, Tian X, et al. Enhanced skin penetration of curcumin by a nanoemulsion-embedded oligopeptide hydrogel for psoriasis topical therapy. RSC Med Chem. 2025. doi:10.1039/d4md00781f
- Ahmad A, Akhtar J, Ahmad M, Islam A, Khan MI, et al. Curcumin Nanogel Preparations: A Promising Alternative for Psoriasis Treatment. Curr Drug Metab. 2024;25:179. doi:10.2174/0113892002312605240508042634
- Lu B, Zhong Y, Zhang J, Zhang J. Curcumin-Based Ionic Liquid Hydrogel for Topical Transdermal Delivery of Curcumin To Improve Its Therapeutic Effect on the Psoriasis Mouse Model. ACS Appl Mater Interfaces. 2024;16:17080. doi:10.1021/acsami.3c17091
- Reena K, Mittal S, Faizan M, Jahan I, Rahman Y, et al. Enhancement of Curcumin's Anti-Psoriatic Efficacy via Formulation into Tea Tree Oil-Based Emulgel. Gels. 2023;9. doi:10.3390/gels9120973
- Patel P, Wang JY, Mineroff J, Jagdeo J. Evaluation of curcumin for dermatologic conditions: a systematic review. Arch Dermatol Res. 2023;316:37. doi:10.1007/s00403-023-02754-8
- Cai Z, Zeng Y, Liu Z, Zhu R, Wang W. Curcumin Alleviates Epidermal Psoriasis-Like Dermatitis and IL-6/STAT3 Pathway of Mice. Clin Cosmet Investig Dermatol. 2023;16:2399. doi:10.2147/CCID.S423922
- Cai Z, Wang W, Zhang Y, Zeng Y. Curcumin alleviates imiquimod-induced psoriasis-like inflammation and regulates gut microbiota of mice. Immun Inflamm Dis. 2023;11:e967. doi:10.1002/iid3.967
- Kumar B, Sahoo PK. Augmented Transdermal Delivery of Curcumin for the Effective Management of Plaque Psoriasis - Design, Formulation, Characterisation, and In Vivo Studies. AAPS PharmSciTech. 2023;24:134. doi:10.1208/s12249-023-02595-8
- Kolahdooz H, Khori V, Erfani-Moghadam V, Livani F, Mohammadi S, et al. Niosomal Curcumin Suppresses IL17/IL23 Immunopathogenic Axis in Skin Lesions of Psoriatic Patients: A Pilot Randomized Controlled Trial. Life (Basel). 2023;13. doi:10.3390/life13051076
- Yao Q, Zhai YY, He Z, Wang Q, Sun L, et al. Water-responsive gel extends drug retention and facilitates skin penetration for curcumin topical delivery against psoriasis. Asian J Pharm Sci. 2023;18:100782. doi:10.1016/j.ajps.2023.100782
- Jain H, Devabattula G, Bhat A, Dalvi H, Rangaraj N, et al. Topical delivery of Bruton's tyrosine kinase inhibitor and curcumin-loaded nanostructured lipid carrier gel: Repurposing strategy for the psoriasis management. Pharm Dev Technol. 2022;27:975. doi:10.1080/10837450.2022.2142610
- Jin N, Chen R, Li Y, Zhang Z, Zhang B, et al. Transcutaneous amorphous preparation co-delivering curcumin and modified aptamer as a synergistic approach for the amelioration of psoriasis-like skin inflammation. Eur J Pharm Sci. 2023;180:106314. doi:10.1016/j.ejps.2022.106314
- Zhang S, Wang J, Liu L, Sun X, Zhou Y, et al. Efficacy and safety of curcumin in psoriasis: preclinical and clinical evidence and possible mechanisms. Front Pharmacol. 2022;13:903160. doi:10.3389/fphar.2022.903160
- Ding YF, Wei J, Quan X, Gu W, Xi L, et al. Hyaluronic acid-based supramolecular medicine with polyamines sequestration capability for cooperative anti-psoriasis. Carbohydr Polym. 2022;296:119968. doi:10.1016/j.carbpol.2022.119968
- Zeng L, Yang T, Yang K, Yu G, Li J, et al. Curcumin and Curcuma longa Extract in the Treatment of 10 Types of Autoimmune Diseases: A Systematic Review and Meta-Analysis of 31 Randomized Controlled Trials. Front Immunol. 2022;13:896476. doi:10.3389/fimmu.2022.896476
